{"database":"iProX","file_versions":[],"scores":null,"additional":{"omics_type":["Proteomics"],"submitter":["Xiang Wang"],"species":["Saccharomyces Cerevisiae"],"full_dataset_link":["http://www.iprox.org/page/project.html?id=IPX0011429000"],"submitter_email":["xiangwang@scu.edu.cn"],"submitter_affiliation":["West China Second University Hospital，Sichuan University"],"sample_protocol":[""],"repository":["iProX"],"data_protocol":[""],"additional_accession":[]},"is_claimable":false,"name":"Structural-guided identification of two novel modulators of β-1,3-glucan synthase FKS1","description":"FKS1 is a β-1,3-glucan synthase that plays a critical role in fungal cell wall formation and serves as a key target for antifungal drugs such as echinocandin and ibrexafungerp. However, the molecular mechanisms regulating FKS1 activity remain largely unknown. This study identifies its endogenous inhibitor and stabilizing factor","dates":{"publication":"Thu Mar 20 00:00:00 GMT 2025"},"accession":"PXD062062","cross_references":{"TAXONOMY":["4932"]}}