iProXProteomicsXiang WangSaccharomyces Cerevisiaehttp://www.iprox.org/page/project.html?id=IPX0011429000xiangwang@scu.edu.cnWest China Second University Hospital，Sichuan UniversityiProXfalseStructural-guided identification of two novel modulators of β-1,3-glucan synthase FKS1FKS1 is a β-1,3-glucan synthase that plays a critical role in fungal cell wall formation and serves as a key target for antifungal drugs such as echinocandin and ibrexafungerp. However, the molecular mechanisms regulating FKS1 activity remain largely unknown. This study identifies its endogenous inhibitor and stabilizing factorThu Mar 20 00:00:00 GMT 2025PXD0620624932