iProXProteomicsYuan XieMus Musculushttp://www.iprox.org/page/project.html?id=IPX0015780000yuanxie@cpu.edu.cnChina Pharmaceutical UniversityiProXfalseIP-MS and proteomic analysis of GPR75-interacting proteins in the liver of CDAHFD-induced miceTo investigate the mechanism by which GPR75 promotes metabolic dysfunction-associated steatohepatitis (MASH), we performed proteomic analysis on liver tissues from CDAHFD-fed control and hepatocyte-specific Gpr75-knockdown mice. To identify GPR75-interacting proteins, immunoprecipitation coupled with mass spectrometry (IP-MS) was conducted.The SCIEX Triple TOF 5600+ mass spectrometer was used in an information-dependent mode (IDA) to automatically switch between MS and MS/MS spectra. Data were analyzed using ProteinPilot™ software (SCIEX, Concord, ON, Canada) and the UniProtKB database.Thu Feb 26 00:00:00 GMT 2026PXD07492710090