{"database":"iProX","file_versions":[],"scores":null,"additional":{"omics_type":["Proteomics"],"submitter":["Xiaodong Ma"],"species":["Homo Sapiens"],"full_dataset_link":["http://www.iprox.org/page/project.html?id=IPX0016332000"],"submitter_email":["maxiaodong@m.scnu.edu.cn"],"submitter_affiliation":["South China Normal University"],"sample_protocol":[""],"repository":["iProX"],"data_protocol":[""],"additional_accession":[]},"is_claimable":false,"name":"4D label-free quantitative proteomics of primary treatment-naive small cell lung cancer (SCLC) tumors and paired normal adjacent tissues","description":"Proteomic analysis was performed on 12 pairs of treatment-naive primary small cell lung cancer (SCLC) tumors and matched normal adjacent tissues (NATs) using 4D label-free quantitative HPLC-MS/MS. Briefly, proteins were extracted from frozen tissue samples, digested into peptides, and analyzed on a Q Exactive HF-X mass spectrometer coupled with an EASY-nLC 1200 system. Raw data were searched against the UniProt Human database using MaxQuant (v2.2.1.0), and differential proteins were identified using Perseus software with thresholds of |log2FC| > 1 and P < 0.05.","dates":{"publication":"Wed Mar 25 00:00:00 GMT 2026"},"accession":"PXD076134","cross_references":{"TAXONOMY":["9606"]}}