{"database":"iProX","file_versions":[],"scores":null,"additional":{"omics_type":["Proteomics"],"submitter":["Bao Zhao"],"species":["Homo Sapiens"],"full_dataset_link":["http://www.iprox.org/page/project.html?id=IPX0016505000"],"submitter_email":["Zhaobao@ihm.ac.cn"],"submitter_affiliation":["Institute of Health and Medicine, Hefei Comprehensive National Science Center"],"sample_protocol":[""],"repository":["iProX"],"data_protocol":[""],"additional_accession":[]},"is_claimable":false,"name":"Mechanism of targeting mitochondrial calcium signaling to promote tumor ferroptosis and activate antitumor immune response","description":"Elucidate the precise mechanism by which MCU regulates ferroptosis in tumor cells through modulating the acetylation of GPX4 to affect its enzymatic activity.Clarify the molecular mechanism by which MCU-regulated ferroptosis in tumor cells activates the anti-tumor immune response of CD8+ T cells.","dates":{"publication":"Thu Apr 02 00:00:00 GMT+01:00 2026"},"accession":"PXD076544","cross_references":{"TAXONOMY":["9606"]}}