iProXProteomicsQiying ZhuHomo Sapienshttp://www.iprox.org/page/project.html?id=IPX0016511000zhuqiying123451@163.comThe First Affiliated Hospital of Xinjiang Medical UniversityiProXfalseEpitranscriptomic m6A reader HNRNPC amplifies oxidative stress–autophagy dysregulation and aggravates placental dysfunction in preeclampsiaWe integrated transcriptomic, proteomic, and untargeted metabolomic profiling of placentas from PE patients and normotensive controls, followed by validation in an independent clinical cohort. Mechanistic roles were interrogated using hypoxia-treated HTR-8/SVneo trophoblasts and an L-NAME–induced PE-like mouse model. Autophagy dynamics were assessed using dual-fluorescent autophagic flux reporters, transmission electron microscopy, and molecular markers.Fri Apr 03 00:00:00 GMT+01:00 2026PXD0765499606