{"database":"iProX","file_versions":[],"scores":null,"additional":{"omics_type":["Proteomics"],"submitter":["Lin Wang"],"species":["Homo Sapiens"],"full_dataset_link":["http://www.iprox.org/page/project.html?id=IPX0017193000"],"submitter_email":["248439206@qq.com"],"submitter_affiliation":["The Fourth Affiliated Hospital of Soochow University"],"sample_protocol":[""],"repository":["iProX"],"data_protocol":[""],"additional_accession":[]},"is_claimable":false,"name":"Proteomic Profiling of CSF and Serum in Recurrent High-Grade GBM Patients During CAR-T Therapy: Novel Biomarkers and Pathway Implications","description":"We prospectively collected 36 paired cerebrospinal fluid (CSF) and serum (SE) samples from 3 recurrent high-grade GBM patients (overall survival > 12 months) at baseline (Day 0) and on post-CAR-T treatment days 1-5. Comprehensive untargeted proteomic profiling was conducted using liquid chromatography-mass spectrometry (LC-MS). We characterized inter-sample proteomic variations through proteomic approaches, elucidated exploratory proteomic changes observed in patients receiving CAR-T therapy, and conducted systematic functional annotation.","dates":{"publication":"Tue May 19 00:00:00 BST 2026"},"accession":"PXD078594","cross_references":{"TAXONOMY":["9606"]}}