{"database":"iProX","file_versions":[],"scores":null,"additional":{"omics_type":["Proteomics"],"submitter":["Jinlong Wang"],"species":["Streptomyces Microflavus"],"full_dataset_link":["http://www.iprox.org/page/project.html?id=IPX0017596000"],"submitter_email":["jinlongwang@ucas.ac.cn"],"submitter_affiliation":["Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences"],"sample_protocol":[""],"repository":["iProX"],"data_protocol":[""],"additional_accession":[]},"is_claimable":false,"name":"The profiling of bile acid-inducing proteins in Streptomyces microflavus","description":"To further investigate the potential functions of Streptomyces in the gut, the bile acid-induction experiment was conducted utilizing mass spectrometry for identification. Bile acids (BAs), crucial primary metabolites of cholesterol metabolism, play a vital role in lipid digestion and absorption, enterohepatic circulation, and metabolic regulation. Notably, elevated intestinal bile acid levels are observed during high-fat diet consumption. In the present study, Streptomyces microflavus was stimulated with four distinct bile acids: CA, DCA, CDCA, and UDCA. Subsequently, bacterial cells were harvested, proteins extracted, and data-independent acquisition (DIA)-based proteomic identification performed.","dates":{"publication":"Wed Jun 03 00:00:00 BST 2026"},"accession":"PXD079248","cross_references":{"TAXONOMY":["1919"]}}