iProXProteomicsPinggang DingHomo Sapienshttp://www.iprox.org/page/project.html?id=IPX0017704000pearceding@gmail.comNanjing University of Chinese MedicineiProXfalseA circRNA-encoded protein, circNOP58-466aa, remodels the multiple myeloma microenvironment via liquid-liquid phase separationCircNOP58 was significantly upregulated in MM and was associated with inferior survival outcomes. CircNOP58 encodes a previously uncharacterized 466-amino-acid protein, circNOP58-466aa, that undergoes LLPS through intrinsically disordered regions. CircNOP58-466aa promoted MM progression and remodeled the bone marrow tumor microenvironment by enhancing osteoclast differentiationWed Jun 10 00:00:00 BST 2026PXD0795479606