{"database":"iProX","file_versions":[],"scores":null,"additional":{"omics_type":["Proteomics"],"submitter":["Haitong Wan"],"species":["Rattus Norvegicus"],"full_dataset_link":["http://www.iprox.org/page/project.html?id=IPX0017764000"],"submitter_email":["whtong@126.com"],"submitter_affiliation":["Zhejiang Chinese Medical University"],"sample_protocol":[""],"repository":["iProX"],"data_protocol":[""],"additional_accession":[]},"is_claimable":false,"name":"Data-independent acquisition (DIA) proteomics sequencing of  tMCAO rat brain","description":"To investigate the role of the Jak2/Stat3 pathway in acute cerebral ischemia-reperfusion injury (CIRI), we employed AAV9-mediated gene silencing in a tMCAO rat model. Specifically, AAV9-shNC (control) or AAV9-shJak2 (knockdown) was administered, and analyses were performed at 2 days post-surgery. To further identify downstream targets of Jak2/Stat3 signaling under tMCAO conditions, we conducted DIA proteomics sequencing to compare protein expression profiles between tMCAO+shNC and tMCAO+shJak2 rats.","dates":{"publication":"Thu Jun 18 00:00:00 GMT+01:00 2026"},"accession":"PXD079863","cross_references":{"TAXONOMY":["10116"]}}