iProXProteomicsHaitong WanRattus Norvegicushttp://www.iprox.org/page/project.html?id=IPX0017764000whtong@126.comZhejiang Chinese Medical UniversityiProXfalseData-independent acquisition (DIA) proteomics sequencing of tMCAO rat brainTo investigate the role of the Jak2/Stat3 pathway in acute cerebral ischemia-reperfusion injury (CIRI), we employed AAV9-mediated gene silencing in a tMCAO rat model. Specifically, AAV9-shNC (control) or AAV9-shJak2 (knockdown) was administered, and analyses were performed at 2 days post-surgery. To further identify downstream targets of Jak2/Stat3 signaling under tMCAO conditions, we conducted DIA proteomics sequencing to compare protein expression profiles between tMCAO+shNC and tMCAO+shJak2 rats.Thu Jun 18 00:00:00 GMT+01:00 2026PXD07986310116