iProXProteomicsJing HongHomo Sapienshttp://www.iprox.org/page/project.html?id=IPX0017989000hongjing196401@163.comPeking University Third HospitaliProXfalseMechanical Pressure-Induced Proteome Remodeling in Corneal Epithelial CellsMechanical pressure can substantially alter the mechano-microenvironment of corneal epithelial cells and activate the mechanosensitive channel Piezo1 as well as its downstream interacting proteins. In this study, we will perform immunoprecipitation using an anti-Piezo1 antibody, coupled with mass spectrometry analysis (IP-MS), to systematically identify the differential interactome of Piezo1 in corneal epithelial cells under pressure stimulation, with the aim of revealing the key molecular mechanisms underlying mechanotransduction.Sat Jun 27 00:00:00 BST 2026PXD0802979606