iProXProteomicsLuping RenMus Musculushttp://www.iprox.org/page/project.html?id=IPX0018124000renluping1122@163.comHebei General HospitaliProXfalseDual GIP/GLP-1 receptor agonist tirzepatide ameliorates adipose tissue inflammation in high-fat, high-fructose diet-induced obese mice via the IL-17A/IL-17RA axisThis study aimed to investigate the effects of the glucose-dependent insulinotropic polypeptide/glucagon-like peptide-1 dual-receptor agonist tirzepatide (TZP) on epididymal white adipose tissue (eWAT) inflammation in high-fat/high-fructose (HFHFr) diet–induced obese mice and to elucidate the underlying mechanisms. In addition, the anti-inflammatory effects of TZP were compared with those of the GLP-1 receptor agonist semaglutide (Sema).Thu Jul 02 00:00:00 BST 2026PXD08046210090