{"database":"iProX","file_versions":[],"scores":null,"additional":{"omics_type":["Proteomics"],"submitter":["Kun Cao"],"species":["Homo Sapiens"],"full_dataset_link":["http://www.iprox.org/page/project.html?id=IPX0018260000"],"submitter_email":["caokun@gdmu.edu.cn"],"submitter_affiliation":["The First Dongguan Affiliated Hospital of Guangdong Medical University"],"sample_protocol":[""],"repository":["iProX"],"data_protocol":[""],"additional_accession":[]},"is_claimable":false,"name":"Proteomic profiling of LX-2 cells treated with TGF-beta and DOX versus TGF-beta alone","description":"This project aims to investigate whether doxycycline (DOX) can attenuate TGF-β1-induced fibrotic activation in human hepatic stellate LX-2 cells. We performed quantitative proteomic analysis using LC-MS/MS to compare protein expression profiles between TGF-β1-treated and TGF-β1 plus DOX-treated groups. The results will reveal potential anti-fibrotic mechanisms of DOX and identify key proteins and pathways involved in the regulation of hepatic fibrosis.","dates":{"publication":"Thu Jul 09 00:00:00 GMT+01:00 2026"},"accession":"PXD080784","cross_references":{"TAXONOMY":["9606"]}}