iProXProteomicsKun CaoHomo Sapienshttp://www.iprox.org/page/project.html?id=IPX0018260000caokun@gdmu.edu.cnThe First Dongguan Affiliated Hospital of Guangdong Medical UniversityiProXfalseProteomic profiling of LX-2 cells treated with TGF-beta and DOX versus TGF-beta aloneThis project aims to investigate whether doxycycline (DOX) can attenuate TGF-β1-induced fibrotic activation in human hepatic stellate LX-2 cells. We performed quantitative proteomic analysis using LC-MS/MS to compare protein expression profiles between TGF-β1-treated and TGF-β1 plus DOX-treated groups. The results will reveal potential anti-fibrotic mechanisms of DOX and identify key proteins and pathways involved in the regulation of hepatic fibrosis.Thu Jul 09 00:00:00 GMT+01:00 2026PXD0807849606