{"database":"iProX","file_versions":[],"scores":null,"additional":{"omics_type":["Proteomics"],"submitter":["Shenhai Gong"],"species":["Escherichia Coli Nissle 1917"],"full_dataset_link":["http://www.iprox.org/page/project.html?id=IPX0018826000"],"submitter_email":["gsh0526@smu.edu.cn"],"submitter_affiliation":["Southern Medical University"],"sample_protocol":[""],"repository":["iProX"],"data_protocol":[""],"additional_accession":[]},"is_claimable":false,"name":"Intestinal β-galactosidase affects host health by regulating flavonoid metabolism","description":"Untargeted metabolomic analysis was performed to identify the principal aglycone generated by the engineered Escherichia coli Nissle 1917 strain expressing β-galactosidase (EcN-bgal). Culture supernatants from EcN-bgal and the vector control strain were collected and subjected to LC–MS-based metabolomic profiling. Comparative analysis revealed substantial alterations in the metabolite composition of the EcN-bgal supernatant, enabling the identification of β-galactosidase-dependent metabolites and the characterization of the major aglycone produced by the engineered strain.","dates":{"publication":"Wed Aug 05 00:00:00 GMT+01:00 2026"},"accession":"PXD082253","cross_references":{"TAXONOMY":["316435"]}}