{"database":"JPOST Repository","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Csv":["https://storage.jpostdb.org/JPST000567/files/2-08.csv","https://storage.jpostdb.org/JPST000567/files/1-08.csv","https://storage.jpostdb.org/JPST000567/files/2-10.csv","https://storage.jpostdb.org/JPST000567/files/1-04.csv","https://storage.jpostdb.org/JPST000567/files/2-04.csv","https://storage.jpostdb.org/JPST000567/files/1-10.csv","https://storage.jpostdb.org/JPST000567/files/2-02.csv","https://storage.jpostdb.org/JPST000567/files/1-02.csv","https://storage.jpostdb.org/JPST000567/files/1-05.csv","https://storage.jpostdb.org/JPST000567/files/1-07.csv","https://storage.jpostdb.org/JPST000567/files/2-07.csv","https://storage.jpostdb.org/JPST000567/files/2-09.csv","https://storage.jpostdb.org/JPST000567/files/2-05.csv","https://storage.jpostdb.org/JPST000567/files/1-03.csv","https://storage.jpostdb.org/JPST000567/files/1-09.csv","https://storage.jpostdb.org/JPST000567/files/2-01.csv","https://storage.jpostdb.org/JPST000567/files/1-01.csv","https://storage.jpostdb.org/JPST000567/files/2-03.csv","https://storage.jpostdb.org/JPST000567/files/2-06.csv","https://storage.jpostdb.org/JPST000567/files/1-06.csv"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Proteomics"],"submitter":["Tadashi Yamamoto"],"species":["Homo Sapiens (human)"],"full_dataset_link":["https://repository.jpostdb.org/entry/JPST000567"],"submitter_affiliation":["Niigata University"],"sample_protocol":[""],"repository":["jPOST"],"data_protocol":[""],"pubmed_abstract":["Conventional sauna bathing may have some health benefits as it facilitates relaxing, detoxing and promoting metabolism. However, conventional sauna bathing at a high temperature may be harmful for the body by increasing the risk of heart failure. The nano-mist sauna has been developed to provide nano-size water particles at a lower temperature. Hence, nano-mist sauna bathing is expected to be useful for health without the risks that arise at high temperatures. In this study, we performed a comprehensive proteomics analysis of urine samples obtained from healthy volunteers before and after they had taken a sauna bath with nano-mist (<i>n</i> = 10) or with conventional mist (<i>n</i> = 10) daily for two weeks (4 groups). The average numbers of urine proteins identified by liquid chromatography-linked mass chromatography in each group varied from 678 to 753. Interestingly, the protein number was increased after sauna bathing both with nano-mist or with conventional mist. Quantitative analysis indicated that considerable numbers of proteins were obviously up-regulated, with more than two-folds in urine samples after the nano-mist sauna bathing. The KEGG pathway analysis showed significant stimulation of the lysosome pathway (<i>p</i> = 5.89E-6) after the nano-mist bathing, which may indicate the nano-mist sauna bathing promotes metabolism related to the lysosome pathway more efficiently than conventional mist sauna bathing and may provide more health benefits."],"pubmed_title":["Proteomics Analysis of Urine to Examine Physical Effects of Warm Nano Mist Sauna Bathing."],"pubmed_authors":["Hirao Yoshitoshi Y, Kinoshita Naohiko N, Xu Bo B, Saito Suguru S, Quadery Ali F AF, Elguoshy Amr A, Yamamoto Keiko K, Yamamoto Tadashi T"],"additional_accession":[]},"is_claimable":false,"name":"NGT6","description":"Conventional sauna bathing may have some benefits for health such as relaxing, detoxing and promoting metabolism. However, conventional sauna bathing at a high temperature may be harmful for the body to increase a risk for heart failure. Nano-mist sauna has been developed to provide nano-size water particles at a lower temperature. Hence, the nano-mist sauna bathing is expected to be useful for health without risks at high temperature. In this study, we performed a comprehensive proteomics analysis of urine samples obtained from healthy volunteers before and after they had taken sauna bath with nano-mist (n=10) or with conventional mist (n=10) daily for two weeks (4 groups). The average numbers of urine proteins identified by liquid chromatography-linked mass chromatography in each group were from 678 to 753. Interestingly, the protein number was increased after sauna bathing both with nano-mist or with conventional mist. By a quantitative analysis considerable numbers of proteins were obviously up-regulated with more than two-folds in urine samples after the nano-mist sauna bathing. The KEGG pathway analysis showed significant stimulation of lysosome pathway (p= 5.89E-6) after the nano-mist bathing, which may indicate the nano-mist sauna bathing promote metabolism related to the lysosome pathway more efficiently than conventional mist sauna bathing and may be more beneficial for the health.","dates":{"publication":"Tue Jul 16 00:00:00 BST 2019"},"accession":"PXD013155","cross_references":{"TAXONOMY":["9606"],"pubmed":["31109144"]}}