{"database":"LINCS","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["http://lincsportal.ccs.miami.edu/dcic/api/download?path=LINCS_Data/HMS_LINCS&file=LDS-1487.tar.gz"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Multiomics"],"submitter":["Jinhua Wang"],"funding":["NIH U54HG005032-01; NIH U54HG006093-01"],"technology_type":["KINOMEscan","Fluorescence 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LINCS (Harvard Medical School)"],"sample_protocol":["The KINOMEscan assay platform is based on a competition binding assay that is run for a compound of interest against each of a panel of 317 to 456 kinases. The assay has three components: a kinase-tagged phage, a test compound, and an immobilized ligand that the compound competes with to displace the kinase. The amount of kinase bound to the immobilized ligand is determined using quantitative PCR of the DNA tag.  Results for each kinase are reported as \"Percent of control\", where the control is DMSO and where a 100% result means no inhibition of kinase binding to the ligand in the presence of the compound, and where low percent results mean strong inhibition."],"repository":["LINCS"],"data_protocol":[""],"additional_accession":[]},"is_claimable":false,"name":"Torkinib KINOMEscan","description":null,"dates":{"publication":"2017-09-29","updated":"2017-09-29"},"accession":"LDS-1487","cross_references":{}}