MassIVEapplication/xmlftp://massive.ucsd.edu/v02/MSV000083585/primaryOK2000000ProteomicsStephanie ColognaAgilent 6550 QTOFQExactive ClassicHomo Sapiens (ncbitaxon:9606)Mus Musculus (ncbitaxon:10090)https://massive.ucsd.edu/ProteoSAFe/dataset.jsp?task=add7dc09125f42f5bda2c77cab3f6655University of Illinois at Chicagocologna@uic.eduMassIVE9,933UNIMOD:4 - "Iodoacetamide derivative."UNIMOD:259 - "13C(6) 15N(2) Silac label."UNIMOD:730 - "Representative mass and accurate mass for 113, 114, 116 & 117."UNIMOD:267 - "13C(6) 15N(4) Silac label."malignant ovary neoplasm, human being, determination, ovarian neoplasm, tumor of the ovary, cancer of the ovary, cancer of ovary, somatic, supernumerary, Concept, malignant tumour of ovary, ovarian cancer, carcinoma of ovary, Role Concept, ovarian carcinoma, ovarian malignant tumour, epithelial, Roles, malignant tumor of the ovary, malignant Ovarian tumor, chemical analysis, malignant ovarian tumor, malignant ovarian tumour, Role, ovary carcinoma, Concepts, ovary cancer, increased, carcinoma of the ovary, Tumor., malignant tumor of ovary, increased number, ovarian epithelial cancer, OC, man, epithelial ovarian cancer, malignant neoplasm of the ovary, human, primary ovarian cancer, ovary neoplasm, present in greater numbers in organism, malignant neoplasm of ovary, malignant ovarian neoplasm, Pax-8, EOS, tumor of the Ovary, ovarian malignant tumor, Role Concepts, assay, tumour of the ovary, accessory, malignant tumour of the ovarygrade 3/4, grade IV, tumor cell migration, Micelle, G3, G4, neoplasm metastasis, grade 3, grade 4, high grade, cancer metastasis, Thiactin, Concept, Bryamycin., undifferentiated, Role Concept, Pax-8, Roles, Role Concepts, poorly differentiated, grade III, proteomic analysis, Role, Concepts, Thiostrepton, Gargon, tumor metastasis0trueProteomic analysis reveals a role for PAX8 in high grade serous ovarian cancer metastasis that can be targeted with micelle encapsulated thiostreptonWe used proteomic and transcriptomic analysis to examine the role of PAX8 leading to increased migratory capabilities in a human ovarian cancer model as well as in tumor models derived from the OSE and FTE.Sun Mar 17 10:29:00 GMT 2019MSV000083585