{"database":"MassIVE","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://massive-ftp.ucsd.edu/v04/MSV000090293/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":{"citationCount":0,"reanalysisCount":0,"viewCount":0,"searchCount":0},"additional":{"omics_type":["Proteomics"],"submitter":["Kathleen Rein"],"instrument_platform":["Orbitrap Fusion Lumos"],"species":["Homo Sapiens (ncbitaxon:9606)"],"full_dataset_link":["https://massive.ucsd.edu/ProteoSAFe/dataset.jsp?task=f04939a55d8841da92b6656437e77d39"],"submitter_email":["reink@fiu.edu"],"submitter_affiliation":["Florida International University"],"sample_protocol":[""],"repository":["MassIVE"],"file_size":["11"],"ptm_modification":["UNIMOD:1342 - \"Sixplex iodoacetyl Tandem Mass Tag.\""],"data_protocol":[""],"name_synonyms":["Ziken, Acrylic aldehyde, human being, Unfolded Protein Responses, 2 Mercaptoethanesulfonate, UCB 3983, Modern, lymphoblastic, Allyl, total expressed protein, Ethanesulfonic acid, MESNA cell, Protein Response, Cell, ASTA-D 7093, Mistabronco, Human, Uromitexan, Mitexan, Homo sapiens, Mesnex, UCB-3983, Responses, Sodium, Acrylic Aldehyde, Man, Acrylic, ASTA D 7093., Propenal, Mesnum, 2-Mercaptoethanesulfonate, Ethylene, Mistabron, Unfolded Protein, Man (Taxonomy), 2 Propenal, Coenzyme M, Aqualin, 2-Propenal, UCB3983, Unfolded, Mucofluid, Ethylene Aldehyde, human, monosodium salt, MESNA-cell, 2-Mercaptoethanesulphonate, Acraldehyde, Aldehyde, Modern Man, Response, 2-mercapto-, brevetoxin 1, Allyl Aldehyde, Sodium 2-Mercaptoethanesulphonate, Proteomes, humans, Acrylaldehyde, ASTAD 7093, Protein Responses"],"description_synonyms":["Dimethyl, Methane, GH05739, sulfinylbis-, Controlling, DMSO, preventive therapy, human being, LcpIII, dimethyli sulfoxidum, dmso, Modern, methylsulfinylmethane, lymphoblastic, e(Pc), dimethylsulfoxyde, Rimso 100, L[[3]]CP3, Cell, prevention, Human, Ion Level, Sodium-23, (CH3)2SO, Sulphoxide, sodio, III, Homo sapiens, GH14582, Dimexide, Dimethylsulphoxide, sodium, 3, Sodium, Sodium Ion, Sulfoxide, LCP3, Sulfinylbis(methane), Level, prevention and control, Man, natrium, Rheumabene, Sodium Ion Level, S(O)Me2, Rimso 50, DmelCG2043, Acid, sulfinylbis(methane), DmelCG7776, Man (Taxonomy), lcp3, DMLCP3, reference sample, l(2)28-28-12, Rimso50, prophylaxis, LCP-3, dimethyl sulphoxide, Na, dimethyl sulfoxide, Sclerosol, Natrium, anon-35Fa, Dimethyl Sulphoxide, human, sample population, Rimso-50, DmelCG5861, preventive measures, Sulfonic, dimetil sulfoxido, sample., 11Na, Rimso, Dimethylsulphinyl, CP3, Dimethylsulfoxide, anon-35Fc, control, DmelLcp3, E(PC), Modern Man, BG:DS02740.11, anon-48Ac, brevetoxin 1, Acids, CG7776, CG2043, dimethyl sulfur oxide, Sodium 23, Dimethylsulfoxid, humans, Controlled, Sulfonic Acid"],"citation_count":["0"],"additional_accession":[]},"is_claimable":false,"name":"Brevetoxin induces a shift in the redox state of the proteome and unfolded protein response in human lymphoblast cells that can be alleviated with the acrolein scavenger MESNA  ","description":"Human lymphoblast cells (GM05581) were treated with \n(i) brevetoxin-2 (5 uM) or \n(ii) a combination of brevetoxin-2 (5 uM) and sodium 2-mercaptoethyl sulfonic acid (500 uM) or \n(iii) equal volume of vehicle (DMSO, control) for 24 h.  \nEach sample is an iodoTMT6plex with 2 replicates of each of the above conditions.\n","dates":{},"accession":"MSV000090293","cross_references":{}}