MassIVEapplication/xmlftp://massive-ftp.ucsd.edu/v06/MSV000093769/primaryOK200Christoph Kaetherhttps://massive.ucsd.edu/ProteoSAFe/dataset.jsp?task=b47168c2da4a4e2796cef41bead7b151Christoph.Kaether@leibniz-fli.deMassIVE28UNIMOD:4 - "Iodoacetamide derivative."UNIMOD:1 - "Acetylation."UNIMOD:35 - "Oxidation or Hydroxylation."ProteomicsOrbitrap Exploris 480Homo Sapiens (ncbitaxon:9606)Leibniz Institute on Aging, Fritz Lipmann Institute (FLI)PXD048259falseAlterations in the secretome composition arising from YIPF5 depletion or mutationSecretome analysis was conducted on MCF10A cells with various conditions, including wild-type (wt) cells, YIPF5-depleted cells, cells with mutated YIPF5, and cells with re-expression of wild-type YIPF5. The primary objective was to discern alterations in the secretome composition arising from YIPF5 depletion or mutation. This investigation aimed to shed light on the influence of YIPF5 on the secretory profile of MCF10A cells, providing insights into potential changes in extracellular signaling and cellular communication associated with YIPF5 status.Thu Jan 04 13:47:00 GMT 2024MSV000093769