MassIVEapplication/xmlftp://massive-ftp.ucsd.edu/v07/MSV000096255/primaryOK200Anthony ODonoghuehttps://massive.ucsd.edu/ProteoSAFe/dataset.jsp?task=024b9e1a0cba4b56b3f4507363a9f1c2ajodonoghue@ucsd.eduMassIVE80MS:1002864 - No post-translational-modifications are included in the identified peptides of this datasetProteomicsQ ExactiveSchistosoma Mansoni (ncbitaxon:6183)University of California San DiegoDimethyl, Methane, PSP-94, PS, PR171, PSP94, MSPL, dnf15s2, artificial sequence, Effects, Peptide Library, PS-341, MSPS, postnatal development, NF15S2, d3f15s2, Synthetic Peptide, dimethylsulfoxyde, Rimso 100, growth and development, Spectrum Analyses, bortezomib, prevention, Long Term, (2S)-N-((1S)-1-benzyl-2-(((1S)-3-methyl-1-(((2R)-2-methyloxiran-2-yl)carbonyl)butyl)amino)-2-oxoethyl)-4-methyl-2-(((2S)-2-((morpholin-4-ylacetyl)amino)-4-phenylbutanoyl)amino)pentanamide, Multicatalytic Proteinase, HGFL, Sulphoxide, Multicatalytic Endopeptidase Complex, Phage Display Library, Mass, hgfl, Random Peptide Library, Analysis, Hepatocyte growth factor-like protein alpha chain, synthetic genetic interaction (sensu inequality), prevention and control, Effect, MSPB, Rheumabene, Mass Spectroscopy, S(O)Me2, Mass Spectrum Analysis, sulfinylbis(methane), Synthetic, GP63, reference sample, Analyses, Macropain, Longterm, Random Peptide Libraries, Complex, Hepatocyte growth factor-like protein beta chain, dimethyl sulphoxide, inhibiteur, synthetic genetic interaction defined by inequality, Long-Term, Synthetic Peptide Library, Proteasome Endopeptidase, 20S Proteasome, SP, Rimso-50, preventive measures, dimetil sulfoxido, Rimso, Dimethylsulphinyl, Multicatalytic Endopeptidase, inhibidor, Dimethylsulfoxide, Multicatalytic, MSP, TMPRSS11, DNF15S2, Macroxyproteinase, LDP 341, 26S proteasome, Long-Term Effect, PS 341, Long-Term Effects, Dimethylsulfoxid, Controlled, PS341, PSP57, inhibitors, sulfinylbis-, Controlling, DMSO, Proteinase, HPC13, preventive therapy, Endopeptidase Complex, dimethyli sulfoxidum, dmso, mSP, msp, LDP341, Velcade, methylsulfinylmethane, nf15s2, Longterm Effect, inhibitor, Random, artificial gene, synthetic DNA, Libraries, Spectrum Analysis, PR-171, Peptide, Proteasome, PRPS, Spectroscopy, development, Ingensin, LDP-341, (CH3)2SO, MS, Dimexide, Macrophage-stimulating protein, PSP, Dimethylsulphoxide, Long Term Effects, IX14, synthetic, Synthetic Peptide Libraries, Kyprolis, Sulfoxide, Sulfinylbis(methane), D3F15S2, Library, Mass Spectrum Analyses, Synthetic Peptide Combinatorial Library, Rimso 50, IGBF, proteasome, Mass Spectrum, Peptide Libraries, Prosome, Macrophage stimulatory protein, Rimso50, prophylaxis, INV, postnatal growth, Spectrometry, dimethyl sulfoxide, Sclerosol, Dimethyl Sulphoxide, 20S, Peptide Phage Display Library, PN44, synthetic constructs, Random Peptide, Phage Display Peptide Library, Longterm Effects, SYNTHETIC CONSTRUCT sequences, control, 341, artificial, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, dimethyl sulfur oxide, multicatalytic endopeptidase, growth, Peptide., proteasome endopeptidase complexPSP57, PSP-94, Proteinase, HPC13, PSP94, MSPL, Endopeptidase Complex, dnf15s2, mSP, msp, MSPS, postnatal development, NF15S2, d3f15s2, nf15s2, growth and development, Proteasome, PRPS, development, Ingensin, Multicatalytic Proteinase, HGFL, Multicatalytic Endopeptidase Complex, Macrophage-stimulating protein, PSP, IX14, hgfl, Hepatocyte growth factor-like protein alpha chain, Bilharzias, D3F15S2, IGBF, proteasome, GP63, Macropain, Prosome, Macrophage stimulatory protein, Complex, INV, Hepatocyte growth factor-like protein beta chain, postnatal growth, 20S, Proteasome Endopeptidase, 20S Proteasome, Bilharzia, Schistosomas, PN44, SP, Multicatalytic Endopeptidase, Multicatalytic, MSP, TMPRSS11, DNF15S2, Macroxyproteinase, 26S proteasome, MSPB., species, multicatalytic endopeptidase, growth, proteasome endopeptidase complexPXD057369falseDevelopment of subunit-selective proteasome substrates for Schistosoma species by MSP-MSDevelopment of optimized subunit-specific substrates for S. mansoni proteasome (Sm20S) based on data generated by Multiplex Substrate Profiling by Mass Spectrometry (MSP-MS). MSP-MS was performed with a library of 228 synthetic tetradecapeptides. Sm20S was incubated for 1h and 3h with Bortezomib, Carfilzomib, DMSO (vehicle control), and the absence of inhibitor or vehicle control (time 0 samples). Assays were conducted in quadruplicate by incubating Sm20S with the peptide library.Wed Oct 30 13:52:00 GMT 2024MSV000096255