Metabolites were extracted and profiled by LC-MS. Differential metabolites were identified using VIP > 1.0 and p < 0.05 and analyzed for pathway enrichment through the Suzhou Panomix Biomedical Technology Co., Ltd’s cloud-based platform.
"],"repository":["MetaboLights"],"study_status":["Public"],"ptm_modification":[""],"instrument_platform":["Liquid Chromatography MS - alternating"],"chromatography_protocol":["The LC analysis was performed on a Vanquish UHPLC System (Thermo Fisher Scientific, USA).
Chromatography was carried out with an ACQUITY UPLC HSS T3 Column (2.1 × 100 mm, 1.8 μm)
(Waters, Milford, MA, USA). The column maintained at 40 ℃. The flow rate and injection volume
were set at 0.3 mL/min and 5 μL, respectively.
"],"publication":["Spatiotemporal iron-hijacking hydrogel reprograms host-pathogen iron homeostasis for fungal keratitis therapy."],"submitter_affiliation":["Zhejiang university"],"submitter_name":["Jian He"],"organism_part":["Candida albicans"],"technology_type":["mass spectrometry assay"],"disease":[""],"extraction_protocol":["1. Accurately weigh an appropriate amount of sample into a 2 mL centrifuge tube,add 10 0 mg
glass bead;
2. Add 1000 µL 50% methanol water, vortex for 30 s;
3. Put the centrifuge tube containing the sample into the 2 mL adapter matched with the
instrument, immerse it in liquid nitrogen for rapid freezing for 5 min, take out the centrifuge tube
and thaw at room temperature, put the centrifuge tube into the 2 mL adapter again, install it into
the tissue grinder and grind it at 55 Hz for 2 min;
4. Repeat step 3 twice;
5. Take out the centrifuge tube, centrifuge for 10 min at 12,000 rpm and 4 ℃℃, take all the
s upernatant, transfer it to a new 2 mL centrifuge tube, concentrate and dry it;
6. Accurately add 300 µL of 2 Amino 3 --(2 chloro phenyl) propionic acid (4 ppm) solution
prepared with 50% methanol water to redissolve the sample, filter the supernatant by 0.22 μ m
membrane and transfer into the detection bottle for LC MS detection.
"],"organism":["Candida albicans"],"full_dataset_link":["https://www.ebi.ac.uk/metabolights/MTBLS13715"],"author":["Zhou Min. Zhejiang university. zhoum@zju.edu.cn.","He Jian. hejianhj@zju.edu.cn."],"data_transformation_protocol":["Metabolites were extracted and profiled by LC-MS. Differential metabolites were identified using VIP > 1.0 and p < 0.05 and analyzed for pathway enrichment through the Suzhou Panomix Biomedical Technology Co., Ltd’s cloud-based platform.
"],"study_factor":["Group"],"submitter_email":["hejianhj@zju.edu.cn"],"sample_collection_protocol":["Candida albican treated with PGaDH were collected, immediately frozen in liquid nitrogen, and stored at −80 °C until analysis.Untargeted metabolomics analysis was performed on Candida albican samples.
"],"omics_type":["Metabolomics"],"study_design":["Iron homeostasis","Candida albicans","Iron Chelating Agents","untargeted metabolites"],"curator_keywords":["Iron homeostasis","Candida albicans","Iron Chelating Agents","untargeted metabolites"],"mass_spectrometry_protocol":["Mass spectrometric detection of metabolites was performed on Orbitrap Exploris 120 (Thermo
Fisher Scientific, USA) with ESI ion source. Simultaneous MS1 and MS/MS (Full MS-ddMS2 mode,
data-dependent MS/MS) acquisition was used. The parameters were as follows: sheath gas
pressure, 40 arb; aux gas flow, 10 arb; spray voltage, 3.50 kV and -2.50 kV for ESI(+) and ESI(-),
respectively; capillary temperature, 325 ℃ ; MS1 range, m/z 100-1000; MS1 resolving power,
60000 FWHM; number of data dependant scans per cycle, 4; MS/MS resolving power, 15000FWHM; normalized collision energy, 30%; dynamic exclusion time, automatic
"],"metabolite_name":["S-Adenosylmethioninamine","dGDP","Phenylpyruvate","Thymidine-5'-monophosphoric acid","Gentamicin","Anatabine","1,3-dihydroxy-N-methylacridone","14-apo-beta-carotenal","ACMC-20my24","Ectoine","1-Adgmi","L-Histidine","Inositol cyclic phosphate","2-Methyl-2-vinyloxirane","Citrulline","dapdiamide A","Flavin mononucleotide","Methyl indole-3-acetate","S-(2-Methylpropionyl)-dihydrolipoamide-E","N-Methylethanolaminium phosphate","Galegine","cis-p-Coumaric acid","Methylimidazole acetaldehyde","6,8-Dimethyl-6,7-didehydroergoline","Pantoate","dapdiamide C","4-Hydroxybenzaldehyde","Picolinamide","Roquefortine L","3,5-Dichloro-2-methylmuconolactone","Prostaglandin E1","Vermelone","Pinostilbene","4,4-Diaponeurosporen-4-al","N2-Succinyl-L-ornithine","3,4-Dihydroxymandelic acid","Dihydroneopterin phosphate","FA 18_3;O3","D-Xylulose-5-phosphate","Mevalonic acid","Frangulin B","Ricinine","Taurohyocholate","Abscisic alcohol","gamma-Butyrolactone","6-Deoxocastasterone","Glutathione","3-Vinylcatechol","Caffeic acid","(-)-Thebaine","Plastoquinol A","Oleamide","3-phosphoglycerate","Palmitaldehyde","6-deoxyerythronolide B","Lidocaine","Pluviatolide","(3E,7E)-4,8,12-Trimethyl-1,3,7,11-tridecatetraene","Pantothenic acid","2-Oxo-4-methylthiobutanoic acid","(22alpha)-Hydroxy-campest-4-en-3-one","Glycerol 3-phosphate","7,7',8,8'-Tetrahydrolycopene","6-Benzylaminopurine","cis-1,2-Dihydro-3-ethylcatechol","5-Carboxyuracil","D-Urobilin","Dibenzothiophene sulfone","19-epi-Cathenamine","(S)-3-Amino-3-phenylpropanoic acid","2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide","Piperideine","Vanillic acid","Canthaxanthin","Phthalic acid","alatolide","2-Thioxo-4-thiazolidinone","Deoxyribose 5-phosphate","Diethylthiophosphate","SCHEMBL16620138","10R-HpODE","Isopiperitenol","2-Cyclohexen-1-one","2,4-Quinolinediol","Oxidized glutathione","chrysoplenol D","Naringin","2-Pentanone","Formamidopyrimidine nucleoside triphosphate","tricoumaroyl spermidine","1,3-Benzenediol","Chenodeoxycholic acid","Androstenedione","Ornithine","Pyridoxate","4,6-Dichloro-3-methylcatechol","3-Hydroxybenzoic acid","2-Naphthyl beta-D-glucopyranoside","1,2-Dihydroxy-3-keto-5-methylthiopentene","Indole","Desethyl atrazine","Iron","Menatetrenone","Gentisate aldehyde","beta-Ionone","P-Hydroxyphenylethanolamine","2-Octaprenyl-6-methoxy-1,4-benzoquinone","Plumbagin","Tigloidine","Furanone A","8,8a-Deoxyoleandolide","3,5-Dibromo-4-hydroxybenzoate","Acetyl-N-formyl-5-methoxykynurenamine","Cyclopentolate","S-Formylmycothiol","PE(18_0_20_4(5Z,8Z,11Z,14Z))","Adenosine","Adenosine monophosphate","1-epi-Valienol 7-phosphate","2,4,5-Trihydroxytoluene","Millettone","L-Alloisoleucine","Bornyl_acetate","Uric acid","Indolepyruvate","Mexiletine","Pterostilbene","Linoleic acid","(S)-2-Acetolactate","Dibucaine","Homo-L-arginine","Ciliatocholic acid","2-Deoxy-D-gluconate","Benzoic acid","Melatonin","L-Phenylalanine","Dodecanamide","Oxaloacetate","4-Methylumbelliferyl acetate","4-Aminobutyraldehyde","Docosahexaenoic acid","Hydantoin-5-propionic acid","10-Deoxymethynolide","O-Acetylserine","4-(Glutamylamino) butanoate","beta-L-Fucose","adonirubin","Propanoyl phosphate","(R)-2,3-Dihydroxy-3-methylvalerate","Uridine diphosphate glucose","bornane-2,6-dione","3-Dehydrosphinganine","Biphenyl","Hallactone B","4-Fluorocatechol","Carbendazim","(S)-10,16-Dihydroxyhexadecanoic acid","Gibberellin A9","Terephthalic acid","Imidazole lactic acid","N-Malonyltryptophan","Zeatin","Tyrosine methylester","Xanthoxylol","L-Cystathionine","3-Hexaprenyl-4,5-Dihydroxybenzoic acid","10-Deoxymethymycin","FA 12_2;O","Pyruvatoxime","Geranyl acetate","2-(4-methylthio)butylmalate","Farnesyl pyrophosphate","pyrethrin I","Umbelliferone","[(1R)-1-hydroxy-2-(trimethylamino)ethyl]phosphonate","ST 28_1;O3","DIMBOA-Glc","2,6,7,4-Tetrahydroxyisoflavanone","N1-hydroxy-roquefortine C","Sterigmatocystin","(25S)-3-oxocholest-4-en-26-al","Phaseollidin","Citicoline","Amidinostreptamine","Xanthosine","Uridine 5'-monophosphate","Citric acid","4-Methoxy-2,2-bipyrrole-5-carboxaldehyde","ACMC-20m5rp","Hydroxymethylphosphonate","omega-Hydroxyphylloquinone","8-Methylnonenoate","Atrazine","Isopentyl acetate","3-Methyl-2-butenal","Retinyl palmitate","1-nitrosonaphthalene","2-Deoxystreptamine","N4-Acetylaminobutanal","5-methylthioadenosine (MTA)","Tauroursodeoxycholic acid","Inosine 5'-monophosphate (IMP)","brevianamide F","Pipecolic acid","O-Phospho-4-hydroxy-L-threonine","[(3S,4S,5S,6R)-3,4,5,6-tetrahydroxycyclohexen-1-yl]methyl dihydrogen phosphate","S-adenosylhomocysteine (SAH)","Diketopiperazine","Homovanillin","2-Deoxyinosose","(2R,3R)-Dihydroflavonol","7-Dehydrocholesterol","Indole-3-carboxaldehyde","Stearic acid","Flavin adenine dinucleotide","2-Oxazolidinone","2-Aminobiphenyl-2,3-diol","UDP-N-Acetyl-D-galactosamine","Cyclohexan","Nitrilotriacetic acid","2E-Dodecenedioic acid","1-deoxy-L-glycero-tetrulose 4-phosphate","Neurosporaxanthin","Tetracenomycin B1","FA 11_1","Glycolithocholate sulphate","Carnitine","Hydroquinone","Cirsimaritin","2-(beta-D-Glucosyl)-sn-glycerol 3-phosphate","3-Methoxy-4-hydroxyphenylglycolaldehyde","Orientin","Iodomethane","Caffeoylmalic acid","Ecgonine methyl ester","Leucodopachrome","(1S,3S,12S,14R,27S)-12-hydroxy-1,3-dimethyl-2,5,15,23,25-pentazaheptacyclo[12.10.2.12,5.06,11.015,24.017,22.012,27]heptacosa-6,8,10,17,19,21,23-heptaene-4,16,26-trione","D-1,5-Anhydrofructose","Epimelibiose","Haloperidol","Propylthiouracil","Pyrimethanil","androst-5-ene-3,17-dione","Tiagabine","3-Sulfopropanediol","(Z)-4',6-Dihydroxyaurone","SCHEMBL12391563","Protoanemonin","2,2,6,6-Tetranitro-4,4-azoxytoluene","Riboflavin (Vitamin B2)","Aconitate [cis or trans]","Acetoacetate","L-Oleandrosyl-oleandolide","Fluorouracil","5-Phosphoribosylamine","protoemetine","¦Ã-Aminobutyric acid","Thymine","1-Methyluric acid","Pelargonic acid","(1R,4S,5R)-4-Thujanol","Graveoline","1-Methyladenosine","D-Xylono-1,5-lactone","Fosinopril","Sorbitol","Taurine","4-Amino-1-piperidinecarboxylic acid","beta-Alanyl-L-lysine","Phenol sulfate","Coenzyme Q9","2-Hydroxybenzaldehyde","9alpha-Hydroxyandrosta-1,4-diene-3,17-dione","1-O-Caffeoyl-beta-D-glucose","Alpha-Cryptoxanthin","4-chloro-L-lysine","L-Threonine","FA 18_0;O","D-Alanyl-D-alanine","3-Methyl-1-(2,4,6-trihydroxyphenyl)-1-butanone","1-hydroxylimonen-2-one","Retronecine","Adenosine phosphosulfate","2-Hexaprenyl-6-methoxyphenol","8-Amino-7-oxononanoic acid","4-Aminophenol","L-Leucine","6,8a-Seco-6,8a-deoxy-5-oxoavermectin 2a aglycone","Dicumarol","Acetohexamide","FAL 8_1","Glycerol","Lycoctonine","3,4-Dehydrorhodopin","Catechol","6alpha-Glucuronosylhyodeoxycholate","Dichloromethane","S-(Indolylmethylthiohydroximoyl)-L-cysteine","(3Z)-Phycoerythrobilin","13-L-Hydroperoxylinoleic acid","6-(alpha-D-Glucosaminyl)-1D-myo-inositol","1-Chloro-2-nitrobenzene","6'-O-p-Coumaroyltrifolin","9-Fluorenone","2,3-dihydroxy-2,3-dihydrobenzoic acid","Calcitriol","62641-07-0","Fructose 1-phosphate","20,21-Diprenylterpendole C","quinolone","SCHEMBL2976928","Leukotriene C4","cis-1,2-Dihydroxycyclohexa-3,5-diene-1-carboxylate","L-Tryptophan","18-Hydroxyoleic acid","Monoethylhexyl phthalic acid","Triethanolamine","Secoisolariciresinol","Baccatin_III","6-Hydroxyparmomomycin","Pinitol","Dopamine","4-Guanidinobutanoic acid","Lycorine","N-Acetyl-beta-alanine","N-Norgramine","Dhurrin","Testosterone","Oleanolic aldehyde","L-Aspartate-semialdehyde","4-hydroxy-2-nonenal (4-HNE)","Glycyrrhetol","Parthenolide","(R)-demethyl-4-deoxygadusol","L-Valine","Uracil","Eicosapentaenoic acid","Iminoaspartic acid","2-Carboxyarabinitol 1-phosphate","Azatyrosine","Tryptamine","Cuminaldehyde","LysoPA(16_0_0_0)","D-Fructuronic acid","4-Methoxyflavanone","Creatine","2-Hydroxybenzyl alcohol","Ropinirole","Isoandrocymbine","2,4-DICHLOROTOLUENE","Racemomycin A","Valerate","Octopine","Cholesterol sulfate","Behenic acid","3-Hydroxy-5-oxohexanoate","Fenbendazole","Aminoundecanoic acid","Tricrocin","2-Hexenal","PROPAMOCARB","Neurosporene","4-Acetamido-2-amino-6-nitrotoluene","1-Benzylpiperazine","Guanidinosuccinic acid","Furanogermenone","Cyanuric acid","4-Pyridoxolactone","Flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside","Diflufenican","Plastoquinone 9","Maritinamine","(1R,5aS,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylic acid","12-oxo-PDA","(-)-trans-Isopulegone","Paraxanthine","gamma-Glutamyl-gamma-aminobutyraldehyde","K-252c","1-Deoxy-D-xylulose 5-phosphate","D-glycero-alpha-D-manno-heptose 1,7-bisphosphate","Nicotine","2-aminobutyrate","meso-Diaminoheptanedioate","3,4-dihydroxy-2-methyl-4-farnesyl-3H-quinolin-1-ium-1-olate","8-Epi-inunolide","5-Hydroxyisourate","Ascorbate radical","5,10-Methylene-THF","4,21-dehydrogeissoschizine","(2S,2S)-Oscillol","2-Oxovaleric acid","Phosphoribulosylformimino-AICAR-P","Taurochenodesoxycholic acid","Isoglutamine","Carbenicillin","D-ribulose-1,5-bisphosphate","CoA 10_1;O","ST 24_4;O4","linolenate(18_3)","Ketospirilloxanthin","D-Gulose","L-Glutamic acid","Zerumbone","benzyl cetraxate","pederin","bendiocarb","Threonic acid","4,4-Dimethylcholesta-8,14,24-trienol","Tiamulin","OA-6129 E","trans-2,3-Epoxysuccinate","Vicianin","Palmitoleic acid","ST 29_3;O","Citraconic acid","Dimethylglycine","3-Hydroxyphenylacetic acid","Terpendole E","5-Amino-6-ribitylamino uracil","Mollicellin C","(R)-3-Ureidoisobutyrate","Gamma-glutamyl-L-putrescine","Isomangiferin","cis-3-Hexenyl acetate","Pseudohypericin","Hydroxychlorobactene","Dihydroxyacetone phosphate","Furcatin","Palmitic acid","delta-Tocotrienol","O-methylandrocymbine","Tetrahydrobiopterin","DIBOA-Glc","Adenosine 3',5'-diphosphate","Saccharopine","4-Hydroxycinnamic acid","2-Hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate","Phylloquinol","(5R,6R)-2,6-dihydroxy-5-(hydroxymethyl)cyclohex-2-en-1-one","sn-glycerol 1-phosphate","Vitamin K","Tyramine","Aminoparathion","3alpha-Hydroxy-3,5-dihydromonacolin L","10-deacetyl-2-debenzoylbaccatin III","Selenocysteine","3b-Allotetrahydrocortisol","Deoxyadenosine","8-demethyl-8-(2,3,4-O-trimethyl-alpha-L-rhamnosyl)tetracenomycin C","5,6-dihydroxy-3-methylquinolin-2(1H)-one","Jadomycin B","9S-HpOTrE","4-Hydroxymethylsalicylaldehyde","D-myo-Inositol 1,4-bisphosphate","3-(2-Methylthio)ethylmalate","Cysteinylglycine","Parapyruvate","N-Acetyl-D-Glucosamine 6-Phosphate","Formononetin","Dihydrosterigmatocystin","Glycerophosphocholine","Ethylmalonate","2-dehydro-D-erythronic acid","5,6-dihydrouracil","droperidol","Medrysone","2-(6-methylthio)hexylmalate","5'-Phosphoribosyl-N-formylglycinamide","(2'E,4'Z,8E)-Colneleic acid","Deoxyamidinoproclavaminate","4-Ketomyxol","Clavulanate","dihomomethionine","Avermectin B1a aglycone","Tulathromycin","Aklavin","5-Oxoavermectin 2a aglycone","Mycinamicin IV","Norspermidine","Salicylic acid","4-Sulfobenzoate","Phosphoenolpyruvic acid","beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-D-Glcp","N-Acetylputrescine","Ergosta-5,7,22,24(28)-tetraen-3beta-ol","Xanthine","gamma-Pentachlorocyclohexene","DKDI","L-Glutamine","Uridine diphosphate glucuronic acid","2-n-Propyl-4-oxopentanoic acid","Coprocholic acid","Asparagine","Fe2+","epsilon-Caprolactone","3-Cresotinic acid","Tromethamine","Lactyl- Brenztraubensaure","ubiquinone-8","D-5-O-Methyl-2,3,5_4,6-pentahydroxycyclohexanone","Trandolaprilat","Flavanone","Nicotinic acid","3-(2-hydroxyphenyl)propionate","3-Hydroxycyclohexanone","L-Isoleucine","N-Carbamoylsarcosine","7-Deoxyloganetin","Leukotriene A4","beta-Citraurin","Maleic acid","8-Hydroxyguanine","(¡À)-Furaneol","Gluconic acid","L-Arabinonate","Choline phosphate","Acacetin","2-Furoic acid","1-Pyrroline-2-carboxylic acid","10-Hydroxycarbazepine","Pentanamide","Eucommiol","Palmitoylcarnitine","Exemestane","Geranyl Phosphate","3-Methylindole","Versiconol acetate","18-Oxooleate","N-Ethylammelide","2-Pyrone-4,6-dicarboxylate","8-Oxo-dGMP","1-Methylpyrrolinium","indole-3-glycol aldehyde","(-)-Arctigenin","Pentalenolactone E","4-Nitrocatechol","2-Chlorophenol","Formylisoglutamine","Pentalenolactone D","L-Aspartic acid","6,7-Dimethyl-8-(1-D-ribityl)lumazine","17alpha,21-Dihydroxypregnenolone","2-Oxoadipic acid","2-Deoxycastasterone","fumiquinazoline F-indoline-2,3-diol","Ternatin C5","4-Hydroxyphenylpyruvic acid","(E)-3-(2,3-Dihydroxyphenyl)-2-propenoic acid","Abietinol","3,6-dichlorocatechol","Camalexin","Uridine triphosphate","Fenoprofen","Fumiquinazoline C","(R)-Sulcatol","Malvidin 3-glucoside","Fumiquinazoline F","Dethiobiotin","10-Hydroxy-3-methoxy-1,3,5,7-cadinatetraen-9-one","Rutin","Sulfite","Xylitol","Dihydromethanophenazine","2,3,4,5-Tetrahydro-2-pyridinecarboxylic acid","Amygdaloside","Phosphonoformyl-CMP","beta-Ethynylserine","sn-3-O-(geranylgeranyl)glycerol 1-phosphate","gamma-Tocotrienol","Glycerylphosphorylethanolamine","Phosphoglycolic acid","N,N-dihydroxy-L-valine","P-Coumaraldehyde","CDP","Cephalosporin C","dihydro-3-hydroxy-4,4-dimethyl- 2(3H)-Furanone","Urolithin B","Urolithin C","Decaprenyl phosphate","Juvenile hormone III","Cuminyl alcohol","Chlorobenzene","Littorine","Trans-4-hydroxyproline","Oxopent-4-enoate","6-Hydroxyhexanoic acid","Paraoxon","Biotin","beta-Carboline","Pentalenate","L-Proline","Bursehernin","Cysteineglutathione disulfide","Neomycin","3-Hydroxyanthranilic acid","Ursolic acid","omega-Hydroxy-beta-dihydromenaquinone-9","FA 6_2;O","2-Aminovalienone","Dicyclohexylamine","Q27132134","5-Aminoimidazole ribonucleotide","Carbamic acid","Triacetic acid","2-Octaprenyl-3-methyl-6-methoxy-1,4-benzoquinone","Psychosine sulfate","Butyrylcarnitine","D-Arabinono-1,4-lactone","3-Hydroxykynurenamine","3,4-Dihydro-9H-fluorene-3,4-diol","5-chlorobenzene-1,2,4-triol","4-Methylaminobutanal","Guanosine monophosphate","3-Ethylphenol","Oleic acid","ST 27_1;O","Glutaric acid","4-Chlorobenzoic acid","Thialysine ketimine","beta-Peltatin A methyl ether","4-Methylaminobutyrate","coniferyl acetate","Adenylsuccinic acid","2-Dehydro-3-deoxy-D-fuconate","Gentamicinc1A","Moupinamide","DMPP","Pseudouridine","Benzoxazolinate","5-(Hydroxymethyl)-2-methylpyrimidin-4-OL","Norlaudanosoline","ABA-GE cpd","Curcumin monoglucoside","Validamine 7-phosphate","jadomycin A","4-Hydroxybenzeneacetonitrile","Argininosuccinic acid disodium","L-Formylkynurenine","3-hexenal","Betulinic acid","alpha-D-Aldosyl beta-D-fructoside","Geranylgeranyl bacteriochlorophyllide a","Chlorpropham","5,6-Dihydrothymine","Alloepipregnanolone","5-Hydroxyconiferaldehyde","Diethylphosphate","Isovaleric acid","Sinapyl alcohol","Glyceraldehyde 3-phosphate","1,3-Cyclohexanedione","D-Fucose","GLUFOSINATE","Pinoresinol","Methacrylyl-CoA","episterone","dUDP","3-Methylxanthine","ISOPHTHALIC ACID","Chrysophanol-9-anthrone","(R)-beta-Aminoisobutyric acid","Pyridoxamine 5'-phosphate","4-Oxalomesaconate","Biliverdin","4-Hydroxy-1-(3-pyridinyl)-1-butanone","4-Hydroxymandelate","2-Hydroxy-2-[2-oxo-2-[[4-[(3-aminopropyl)amino]butyl]amino]ethyl]-2-[2-oxo-2-[[4-[[3-[(3,4-dihydroxybenzoyl)amino]propyl]amino]butyl]amino]ethyl]acetic acid","2-Aminoisobutyric acid","Homocitric acid","2-Phosphoglyceric acid","2-Methylene-4-oxopentanedioic acid","methyl gibberellin A9","UDP-alpha-D-galactofuranose","Pyrophosphate","Uridine","2,3,6-Trihydroxypyridine","1-Methoxy-4-(2-propenyl)benzene","Anilazine","Juglone","Phosphoribosyl formamidocarboxamide","(¡À)-2-Hydroxy-2-phenylacetonitrile","3-Sulfinoalanine","N(4)-aminopropylspermidine","Fluoroacetaldehyde","O-Phosphohomoserine","3-Indoleacetonitrile","Cyanidin 3-glucoside","Geissoschizine","Galloyl glucose","3-Geranylgeranylindole; 3-(Geranylgeranyl)indole","Isoniazid","4'-Phosphopantothenoylcysteine","Thiamine","Galactitol","Dehydroxypaxilline","L-Glutamic gamma-semialdehyde","3-Hydroxyl kyneurenine","Phosphoroselenoic acid","5-Acetamidovalerate","12,13-DiHOME","2-Heptyl-3-hydroxy-quinolone","Butyl 4-aminobenzoate","FA 18_2;O2","Fumaric acid","L-Tyrosine","Acetylcarnitine","Dihydroconiferyl alcohol","4-Hydroxycoumarin","Baicalein","S-Carboxymethyl-L-cysteine","Ureidoglycine","Hypotaurine","Sucrose","2,4-Toluenediamine","2'-Deoxyguanosine 5'-monophosphate","D-Tagatose 6-phosphate","D-Ribulose 5-phosphate","16alpha-hydroxyprogesterone","Melilotoside","3-[(1E,4R)-4-hydroxycyclohex-2-en-1-ylidene]pyruvic acid","Biotin sulfoxide","gamma-Glutamyl-alpha-aminobutyrate","Spheroidenone","4-Nitroquinoline N-oxide","(R)-Amphetamine","CID 440908","Cannabisin E","7-Cyano-7-deazaguanine","10,11-Epoxy-3-geranylgeranylindole","3-Aminopropionaldehyde","Spermidine","Triethylamine","4-demethyl-","Indole-5,6-quinone","chloric acid","D-Erythro-imidazole-glycerol-phosphate","Aflatoxin M1","2-methyl-6-solanyl-1,4-benzoquinol","3-Oxalomalic acid","5-Methylthioribose","1,3,7-trimethylurate","7-hydroxy-4-isopropenyl-7-methyloxepan-2-one","ST 28_2;O4","Dihydrovaltrate","AdoMet","NA 28_8;O2","5-epi-Lividomycin B","4-Hydroxyretinoic acid","Sophoraflavanone G","6-Hydroxyflavanone","P 518","Acetone cyanohydrin","Anhydrorhodovibrin","Scopolin","2,3,4,6-Tetrahydroxybenzophenone","2-Hydroxy-3-carboxybenzalpyruvate","4-Acetylbutyrate","Suberic acid","Formyl-5-hydroxykynurenamine","Isovaleraldehyde","5-Hydroxyindoleacetaldehyde","Pyridoxal 5'-phosphate","Ginsenoside Rg3","5'-Phosphoribosyl-N-formylglycinamidine","4-Nitrophenol","Piperine","PC(16_0_18_1(9Z))","Cyclohexanone","Benzimidazole","8-methylthiooctanaldoxime","desulfosinalbin","Octhilinone","Quetiapine","Cefprozil","AKOS006369514","D-Pantethine","Coniferin","Farnesyl phosphate","Pyridoxine","Guanidinoacetate","2,4-DINITROANISOLE","D-2-Amino-hexano-6-lactam","1,2-Dihydronaphthalene-1,2-diol","Paspalinine","Oxethazaine","Nicotinamide adenine dinucleotide phosphate","Stachydrine","N-Acetylleucine","1-palmitoyl-dihydroxyacetone-phosphate","(3R,5R,6S,7S,9R,11E,13R,14S)-14-[(1R)-1-hydroxyethyl]-3,5,7,9,13-pentamethyl-2,4,10-trioxo-1-oxacyclotetradec-11-en-6-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside","EDDA","10,11-epoxy-3,11-dimethyl-7-ethyl-2,6-tridecadienoic acid","Histidinal","Valeroidine","Galactose 1-phosphate","Astaxanthin","chlorohexadienedioic acid","2-Amino-3-carboxymuconic acid semialdehyde","Quercetin 3-glucosyl-(1->2)-galactosyl-(1->2)-glucoside","Guanosine diphosphate mannose","gentiobiose","Methanophenazine","Cycloserine","Nicotinamide ribotide","Glycerophosphoric acid","Betaine","Pteridine diphosphate","ST 21_4;O2","L-seryl-adenylate","N-Methylhydantoin","2-hydroxy-3,4-dihydro-2H-1,4-benzoxazin-3-one","Selenium","Fructoselysine 6-phosphate","Ketopantolactone","CDP-ethanolamine","Cyclopentanone","Glycinol","isopentenyl adenosine","Xanthylic acid","7-Acetylintermedine","4-HYDROXYTRYPTAMINE","beta-Cryptoxanthin","Naphthalene epoxide","Chloroquinol","13(S)-Hydroperoxylinolenic acid","3-Dehydro-2-deoxyecdysone","Isoquinoline","Tryptophol","Methylarsonate","L-Lysine","Capsiamide","D-glucaro-1,5-lactone","Phosphoserine","(R)-Acetoin","Nalpha-Methylhistidine","Isobutanal oxime","Dimethylbenzimidazole","5-Amino-6-(5-phosphoribosylamino)uracil","3-Methylmuconolactone","Eugenol","Limonoate","Dodecanoic acid","Uridine 5'-diphosphate","Pseudoephedrine","isoroquefortine C","Sphinganine","Phosphohydroxypyruvic acid","Perakine","2-Hydroxyoctadecanoic acid","Tetrahydrofolic acid","kaempferol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-glucosyl-(1->2)-beta-D-glucoside","threo-b-methylaspartate","PE 40_4","3-Carbamoyl-2-phenylpropionic acid","Toluene-cis-dihydrodiol","Valienone","Premithramycin A3","Diphyllin","Menaquinone-9","FAL 16_1","Premithramycin A2","Sulfate","Isonicotinic acid","Styrene cis-glycol","4,4-Diaponeurosporene","7a-Hydroxy-cholestene-3-one","5-methylthiopentanaldoxime","2,5-Bis(hydroxymethyl)furan","L-Homoserine","D-Xylose","Dihydrofolic acid","9(S)-HPODE","CHEMBL441356","FA 8_1","N-hydroxy-L-phenylalanine","3-Dehydroecdysone","L-Lysopine","4-O-beta-D-Mannopyranosyl-D-mannopyranose","Guanosine diphosphate","27-Deoxy-5b-cyprinol","4-Hydroxy-2-butenoic acid gamma-lactone","4alpha-hydroxymethyl-ergosta-7,24(241)-dien-3beta-ol","2-Hydroxyadipic acid","DL-Malic acid","Podofilox","2,8-Quinolinediol","Phytol","2-Octaprenyl-6-methoxyphenol","Barbituric acid","Sinapine","Porphobilinogen","13-Desoxyterpendole I","N-Glycoloylganglioside GM2","(+)-Gallocatechin","Dibenzothiophene 5-oxide","3-Methyl-1-butylamine","4-isopropenyl-7-methyloxepan-2-one","Levobunolol","trans-p-Feruloyl-beta-D-glucopyranoside","Biguanide","13-Dihydrocarminomycin","Phaseollin","Protomycinolide IV","Phosphoenol-4-deoxy-3-tetrulosonate","L-Histidinol","Gabapentin","Lecithin","Amidinoproclavaminate","D-Arabino-hexos-2-ulose","Coproporphyrinogen III","aureusidin 6-O-glucoside","2,3-didehydrobutyrine","3-Hexaprenyl-4-hydroxy-5-methoxybenzoic acid","Hyperforin","3-Methoxytyramine","Coumesterol","BROMOBENZENE","14,15-Epoxyemindole SB","Phosphate","geranylhydroquinone","3beta-hydroxy-5-cholestenoate","FADH","4-Hydroxymethylcatechol","Mesembrine","Niacinamide","Salsolinol","Diaminopimelic acid","Propioin","Serotonin","Galactinol","(Z)-[(4-hydroxyphenyl)acetaldehyde oxime]","Sanguinarine","CYCLOHEXANECARBOXYLIC ACID, 4-HYDROXY-3-OXO- 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6_3;O3","7,8-Dihydromethanopterin","Hypoxanthine","Bergaptol","Gigantine","2,4-Dinitrophenol","Linamarin","L-Arginine","FO 2546M","2,6-Diethylaniline","Nevirapine","FUBERIDAZOLE","Ureidoperacrylic acid","6-Hydroxyprotopine","Rishitin","Rhizocticin A","Sulcatone","N-Isopropylammelide","Nnal-N-oxide","Resveratrol","N6,N6,N6-Trimethyl-L-lysine","Galactitol 1-phosphate","FA 18_1;O","2,5-Dichlorophenol","Ophthalmic acid","Aflatrem","Macarpine","N-acetylglucosaminylasparagine","1-Pyrroline-4-hydroxy-2-carboxylate","Adenine","D-Pyroglutamate","3-amino-3-(4-hydroxyphenyl)propanoic acid","Leprotin","6-Deoxy-5-ketofructose 1-phosphate","2-Hydroxy-3-(1H-imidazol-5-yl)propanoic acid","Naloxone","(25R)-26-hydroxycholest-4-en-3-one","fusicocca-2,10(14)-diene","1-Methoxyphenanthrene","Inosine","L-Serine","Purine","N¦Á-Acetyl-L-lysine","corynantheal","Homocysteine","4-methyl-3-oxoadipate-enol-lactone","Bryophyllin A","Lumichrome","ACMC-20dgc9","O-acetylhomoserine","6-O-methyl-N-deacetylisoipecoside aglycon","2,5-dichlorohydroquinone","Cholic acid","Arachidonic acid","(3S)-3-hydroxycyclocitral","6-Chlorohydroxyquinol","trihomomethionine","Lactose 6-phosphate","N-hydroxyl-tryptamine","Mesoxalic acid","Yatein","N-Cyclopropylammelide","Ureidosuccinic acid","1,2-Cyclohexanedione","Isovaleryl-CoA","Vitamin A2 aldehyde","L-Dopaquinone","3-Thiomorpholinecarboxylic acid","Dihydrostreptomycin","D-4-Hydroxy-2-oxoglutarate","Rhamnetin","Terephthalate-1,2-cis-dihydrodiol","4-hydroxymandelic acid","Isoglutamate","Stigmatellin Y","ecdysone","aurachin B epoxide","6-Aminopenicillanic acid","Imperialin","Cucurbitacin D","gamma-Glutamylcysteine","Dimethylpropiothetin","Sebacic acid","N-acetylglutamate","L-Methionine","2-Formylaminobenzaldehyde","(2R)-2-hydroxy-3-(1H-indol-3-yl)propanoic acid","Arginine, N2-benzoyl","N-hydroxy-L-isoleucine","Theophylline","UDP-N-acetylmuramoyl-L-alanine","SAICAR","Medermycin","L-4-Hydroxyglutamate semialdehyde","(¡À)-2-Methylbutanal","Leucyl-leucine","Treosulfan","FA 18_0;O2","5-Amino-2-oxopentanoic acid","Oxytetracycline","17a-Hydroxypregnenolone","Acrylamide","Diisobutyl phthalate","2-oxo-5-Methylthiopentanoic acid","Trithionate","cis-zeatin riboside","Apigenin","Thyroxine","Pyroglutamic acid","Cytidine triphosphate","2-Nitrophenol","Pyridoxamine","Picrocrocin","Glucosamine 6-phosphate","9-methylthiononanaldoxime","Chymosin preparation, escherichia coli k-12","8-oxogeranial","L-pentahomomethionine","Botrydial","Furylfuramide","cis-Acetylacrylate","Dodecanedioic acid","germacradienol","hexahomomethionine","Methyl sulfate","Deoxyguanosine","Gingerol","FA 12_3;O2","N-Methyl-4-dimethylallyltryptophan","Cathine","PE(16_0_18_1(9Z))","(2E)-Decenoyl-ACP","Lipoamide","Sildenafil","Dihydromacarpine","Homoserine, O-succinyl-","L-2-Amino-6-oxopimelate","2-hydroxypropyl-CoM","Phosphodimethylethanolamine","Demethylphylloquinone","Cytidine monophosphate","Dibutyl phthalate","Thymidine","Tranexamic Acid","7-Chlorodehydrotryptophan","Chalcone","5-Acetylamino-6-formylamino-3-methyluracil","Costunolide","Orotic acid","Indole-3-acetamide","Naproxen","3-(all-trans-octaprenyl)benzene-1,2-diol","ditrans,pentacis-Octaprenyl diphosphate","Chrysosplenetin","Dihydromenaquinone-9","Clavaminate","Mevaldate","Magnoline","Bufalin","1-Pyrroline-5-carboxylic acid","Histamine","2-Methyl-4-amino-5-hydroxymethylpyrimidine diphosphate","4-Oxo-1-(3-pyridyl)-1-butanone","Mycocyclosin","24,25-Dihydroxyvitamin D","Imidazole pyruvate","O-Phosphothreonine","2-oxostearic acid","N-Methyl-D-aspartic acid","Prostaglandin F3a","FAMP","L-Fucono-1,5-lactone","2-Methylacetoacetyl-CoA","(3-Phenoxyphenyl)methanol","17a-Ethynylestradiol","4-Hydroxysphinganine","L-2-Amino-3-oxobutanoic acid","Leucocyanidin","Oxazepam","Ribose 1,5-bisphosphate","Taurodeoxycholic acid","Azelaic acid","ST 19_2;O3","D-Tagatose 1,6-bisphosphate","PQQH2","Oxidized Renilla luciferin","2-Aminobenzoic 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