Features (peaks) with a missing rate >50% across all sample groups were filtered out. Remaining missing values were imputed using a two-step method: if the proportion of missing values for a feature was >50%, values were filled with 1/5 of the minimum positive value; otherwise, k-nearest neighbors (KNN) imputation was applied. Peak areas were then corrected using Support Vector Regression (SVR). Metabolite identification was performed by matching the corrected features against a combination of an in-house laboratory database, integrated public databases, and predictive libraries.
"],"repository":["MetaboLights"],"study_status":["Public"],"ptm_modification":[""],"instrument_platform":["Liquid Chromatography MS - negative - reverse-phase","Liquid Chromatography MS - positive - reverse-phase"],"chromatography_protocol":["The chromatographic separation was performed on a Waters ACQUITY UPLC system equipped with an ACQUITY Premier HSS T3 column (1.8 µm, 2.1 mm × 100 mm; Waters, USA). The mobile phase consisted of (A) 0.1% formic acid in water and (B) 0.1% formic acid in acetonitrile. The gradient elution program was set as follows: 0–1.0 min, 95% A; 1.0–3.0 min, 80% A to 1% A; 3.0–4.5 min, held at 1% A; 4.5–4.6 min, changed to 95% A; and 4.6–6.0 min, held at 95% A for column re-equilibration. The column temperature was maintained at 40°C, the flow rate was 0.4 mL/min, and the injection volume was 4 µL.
"],"publication":["Exploring the Effects of Different Exercise Modalities on Skeletal Muscle Function in High-Fat Diet-Induced Obese Mice Based on Gut Microbiota and Metabolomics."],"submitter_name":["Yefan Wang"],"submitter_affiliation":["Shanxi University"],"organism_part":["blood serum"],"technology_type":["mass spectrometry assay"],"disease":[""],"extraction_protocol":["For liquid serum samples, a standardized solvent extraction protocol was employed. Briefly, frozen serum samples stored at -80°C were thawed on ice. After vortexing, a 50 µL aliquot of each sample was transferred to a pre-labeled tube. Metabolites were then extracted by adding 300 µL of ice-cold 20% acetonitrile in methanol containing internal standards. The mixture was vortexed for 3 minutes and centrifuged at 12,000 rpm for 10 minutes at 4°C. The supernatant (200 µL) was transferred to a new tube, held at -20°C for 30 minutes, and centrifuged again at 12,000 rpm for 3 minutes at 4°C. Finally, 180 µL of the clarified supernatant was transferred to an autosampler vial for LC-MS analysis. Quality control (QC) samples were prepared by pooling equal aliquots from all individual samples and were processed identically alongside the experimental samples throughout the entire extraction procedure.
"],"organism":["Mus musculus"],"full_dataset_link":["https://www.ebi.ac.uk/metabolights/MTBLS13878"],"author":["Lijun Wu. Shanxi University. Wlj666888@126.com.","Yefan Wang. Shanxi University. 1321274002@qq.com."],"data_transformation_protocol":["Raw mass spectrometry data were converted from vendor format to mzML format using ProteoWizard software. Subsequent data processing, including peak picking, alignment, and retention time correction, was performed using the XCMS program.
"],"study_factor":["Group"],"submitter_email":["1321274002@qq.com"],"sample_collection_protocol":["Blood samples were collected from the retro-orbital venous plexus of male C57BL/6 mice. After collection, the whole blood was allowed to clot at room temperature for 30 minutes. The serum was then separated by centrifugation at 3,000 rpm for 10 minutes at 4°C. The resulting supernatant (serum) was carefully aliquoted into sterile tubes and immediately stored at -80°C until further metabolomic analysis.
"],"omics_type":["Metabolomics"],"study_design":["Metabolomics","High-Fat Diet-Induced Obesity","Gut Microbiota","Skeletal Muscle Function","Exercise Intervention"],"curator_keywords":["Metabolomics","High-Fat Diet-Induced Obesity","Gut Microbiota","Skeletal Muscle Function","Exercise Intervention"],"mass_spectrometry_protocol":["Mass spectrometric analysis was performed on a Q Exactive HF-X hybrid quadrupole-Orbitrap mass spectrometer (Thermo Fisher Scientific, USA) equipped with an electrospray ionization (ESI) source. Data were acquired in both positive (ESI+) and negative (ESI-) ionization modes. The detailed operating parameters were set as follows: spray voltage, 3500 V for ESI+ and 3200 V for ESI-; sheath gas flow rate, 30 arbitrary units (Arb); auxiliary gas flow rate, 5 Arb; ion transfer tube temperature, 320 °C; vaporizer temperature, 300 °C. Full MS scans were acquired over a mass range of m/z 75–1000 with a resolution of 35,000. The automatic gain control (AGC) target for MS1 was set to 1e6. Data-dependent MS/MS acquisition (Top N = 10) was performed with a resolution of 17,500 (AGC target: 2e5) using stepped normalized collision energies (NCE) of 30, 40, and 50 V. The dynamic exclusion time was set to 3 seconds.
"],"metabolite_name":["Diethyl hydrogen phosphate","DL-2-Aminooctanoic acid","Corticosterone","2,3-Dihydrothienamycin","Acetoxyacetone","(9Z)-heptadeca-1,9-dien-4,6-diyne-3,8-dione","gamma-Aminobutyric acid","Dihydrodaidzein","2-Butyne-1,4-diol","Methyl nicotinate","Propyl 1-(propylsulfinyl)propyl disulfide","Amidosulfonic acid","Altretamine","L-Histidine","L-Allothreonine","Methyl geranate","1,2-Dilinoleoyl-SN-glycero-3-phosphocholine","Bifenazate","Iminodiacetic acid","Nipecotic acid","1-Octadecanoyl-sn-glycero-3-phospho-(1'-myo-inositol)","LPC(18:1/0:0)","Citrulline","Scopoletin","1,5-Naphthalenediamine","N-Ethylglycine","2,3-Dimethoxyphenol","11beta-PGE2","N-Acetyl-D-tryptophan","4-Aminoazobenzene","Picolinamide","1-Undecanol","1-(1Z-octadecenyl)-sn-glycero-3-phosphocholine","2,5-Dimethyl-2,4-hexadiene","3,4-Dihydroxymandelic acid","Ricinine","(3S)-2-oxo-3-phenylbutyric acid","N1-acetylspermine","1-Acetylisatin","L-Theanine","4,4'-Sulfonyldiphenol","Clavamycin B","alpha-Ergocryptine","Fexofenadine","5-(4-Piperidyl)isoxazol-3-ol","Caffeic acid","Isophorone","4-Methyl-5-thiazoleethanol","Proline betaine","Oleamide","Cinnamic Acid","Lidocaine","Pantothenic acid","Colfosceril palmitate","Dehydroevodiamine","1-Benzylimidazole","1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine","6-Benzylaminopurine","6-keto-PGF1¦Á","Tetraethylammonium","7-Ketocholesterol","Drostanolone propionate","Benzocaine","2-Methyl-4-pentenoic acid","Metaproterenol","Indoleacetaldehyde","delta-Hexanolactone","3-Nitrophenylhydrazine","Amitrole","Sulcotrione","Phenylephrine","13-Docosenamide","Carnitine C18:1","Phe-Glu","trans-2-Octenoic acid","Prostaglandin D1","Benzyl alcohol","4beta-Hydroxycholesterol","Disopyramide phosphate","7,8,4'-Trihydroxyisoflavone","Pyridine","3-Phenyl-4-pentenal","3-Methacrylic acid","4-Oxoniocarbonylbenzoate","¦Ä-Valerolactam","3'-Adenylic acid","2-Phenylglycine","3-(2-Hydroxyphenyl)oxirane-2-carbaldehyde","Androstenedione","Ornithine","Norambreinolide","Normirtazapine","4-Hydroxy-4-(3-hydroxy-1-butenyl)-3,5,5-trimethyl-2-cyclohexen-1-one","Asn-Val","Indole","Cysteamine","N-(1-Deoxy-1-fructosyl)valine","4-Hydroxycyclophosphamide","DL-Arginine","Neryl formate","2-Aminoethyl diphenylborinate","Glucuronic Acid","DL-3,4-Dihydroxyphenyl glycol","L-Carnitine","Desmethylsildenafil","Tagatose","o-Cresol","Methazolamide","Adenosine","Dihydroactinidiolide","Allopurinol","L-prolinylglycine zwitterion","Cyasterone","2-Hydroxycinnamic acid","PC(16:0/2:0)","Metepa","1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide","Chlorphenesin","Benzoic acid","Melatonin","Ascorbic acid","Thiodiglycol","Phenformin","Erythritol","prostaglandin A2","3-Dehydrosphinganine","Pyrazin-2-carboxylic acid","Carnitine C3:0","Carnitine C9:1-OH","N-Acetyl-L-tyrosine","Carbendazim","Hexylresorcinol","Quinone","Phenol, 2-((ethylsulfonyl)methyl)-, methylcarbamate","Valeric acid","Tyrosine methylester","1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-D-myo-inositol","3-Hydroxypropanal","Flucytosine","Vildagliptin","1-Oleoyl-2-myristoyl-sn-glycero-3-phosphocholine","Geranyl acetate","Umbelliferone","Lys-Asp","Pterosin N","4-Hydroxy-3-methoxycinnamaldehyde","1-Methylnicotinamide","Dehydrocostus lactone","2-(1-methyl-1H-imidazol-5-yl)acetic acid","5-Phenyl-1,3-oxazinane-2,4-dione","cis-4-Octenedioic acid","3-methoxybenzene-1,2-diol","Glu-Val","Xanthosine","2,3-di(tetradecanoyloxy)propyl hexadecanoate","Citraconic anhydride","¦Â-Alanine","1-Eicosanoyl-sn-glycero-3-phosphocholine","Rimantadine","N-Acetyl-L-arginine","Docosanamide","9-Aminoacridine","Lycomarasmine","1-nitrosonaphthalene","(2R)-piperidin-1-ium-2-carboxylate","Pipecolic acid","PC(18:1(11Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))","Dazomet","(8R,9R,10R,13S,14R,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one","Mirtazapine","Prostaglandin F2beta","Indole-3-carboxaldehyde","Flavin adenine dinucleotide","2-[Hydroxy-(3-octadecanoyloxy-2-octadec-9-enoyloxypropoxy)phosphoryl]oxyethyl-trimethylazanium","DL-Ornithine","2,5,8,11-Tetraoxatridecan-13-ol","[2,3-Dihydroxypropyl(2-hydroxyethyl)amino]phosphonic acid","2,3,4,5-Tetrahydroxypentanoic acid","PC(15:0/20:5(5Z,8Z,11Z,14Z,17Z))","Hydroquinone","Bisphenol A","L-methionyl-L-threonine","4-Fluoro-L-phenylalanine","2-Amino-4-nitrophenol","2-Methyl-1-pyrroline","Noralfentanil","Difurfuryl disulfide","5-Methoxyindoleacetate","L-Tryptophanamide","Dehydrochorismic acid","7alpha-Hydroxycholesterol","Phenylethyl primeveroside","Ethyl 1-methyl-1,2,5,6-tetrahydropyridine-3-carboxylate","Benz[a]acridine","Chloroform","Carbimazole","13,16,19-Docosatrienoic acid","1,5-Dihydroriboflavin","5alpha-Androstane-3alpha,17beta-diol","3-Oxopentanoic acid","Ofloxacin","1,4-Dithiane-2,5-diol","Diethyl maleate","DL-Leucine","(4E,6E)-1-(4-hydroxyphenyl)-7-phenylhepta-4,6-dien-3-one","Benzyl glycinate","Methyl dioxindole-3-acetate","Mesalazine","1H-Benzotriazole","MG(16:0/0:0/0:0)","Procaterol hydrochloride hemihydrate","N-Palmitoylglycine","Taurine","Proxan","Trans-Zeatin","3-Buten-1-ol","2-Hydroxybenzaldehyde","Lithocholic acid","Pramipexole","1,2-Dierucoyl-sn-glycero-3-phosphocholine","2-Aminophenol","Indole 3-Ethanol","(-)-alpha-Terpineol","4-Aminophenol","Trigonelline","(E)-1-Propenyl 1-(propylthio)propyl disulfide","L-Asparagine, N-[2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl]-","LPC(16:1/0:0)","3-Methyl-2,5-dihydrothiophene 1,1-dioxide","17alpha-Hydroxypregnenolone","3-Azaniumyl-4-[(1-methoxy-1-oxo-3-phenylpropan-2-yl)amino]-4-oxobutanoate","Ganoderic acid A","Isobavachalcone","Vitamin e succinate","4-Aminoisoxazolidin-3-one","Aminoethoxyacetic acid","Tetramethylsilane","(3S,4R)-3,4,5-trihydroxy-2-keto-valeric acid","(-)-Bornyl acetate","Geranylgeraniol","trans-Aconitic acid","p-Anisidine","L-Palmitoylcarnitine","(4S)-4-[(2E,4Z)-2,4-Decadienoyloxy]-4-(trimethylammonio)butanoate","2,5-Dihydroxycinnamic acid","methylcarbamyl PAF","Diammonium ethylenebis(dithiocarbamate)","7-Methoxycoumarin","Gossypetin 8-glucuronide 3-sulfate","Quinaldic acid","L-methionine sulfoxide","Rebaudioside C","Methyl 10-undecenoate","Octopamine","Benzidine","L-Tryptophan","Isopropamide","Carnitine C6:0","Syringaldehyde","N,N,N-Trimethyl-Histidine","LPC(15:0/0:0)","FFA(12:1)","Dopamine","Oxoamide","alpha-Fluoro-beta-ureidopropionic acid","gamma-Tocopherol","xi-5-Dodecanolide","Pyrazinamide","Diosphenol","Cholesterol","(1S,2R)-3-Methylcyclohexa-3,5-diene-1,2-diol","Nifedipine","Testosterone","Morpholine","Antimony trioxide","2,6-Diisocyanatotoluene","L-Cysteinesulfinic acid","Myosmine","Amprenavir","TG(18:3(9Z,12Z,15Z)/20:5(5Z,8Z,11Z,14Z,17Z)/20:5(5Z,8Z,11Z,14Z,17Z))","N-oleoylglycine","2,4-Hexadienoic acid","Alanylarginine","3-methyl-3H-imidazo[4,5-f]quinolin-2-amine","N-Acetylaminooctanoic acid","Creatine","Sphingosine 1-phosphate","N-(2-Hydroxyethyl)nicotinamide","LPC(0:0/22:4)","2,6-Dimethoxy-4-propylphenol","Oxiglutatione","3-Nitroacrylic acid","Cytosine","Steviobioside","alpha-Ionone","12-Ketolithocholic acid","2-Acetyl-1,4,5,6-tetrahydropyridine","1-(4-Methoxyphenyl)-4-methylpentan-3-ol","3-(6-Hydroxyindol-3-yl)lactic acid","2-[(4-Methoxy-1-benzouran-5-carbonyl)amino]acetic acid","Hydroxyquinoline","LPC(0:0/22:5)","Acetylvalerenolic acid","Lysylproline","Acetohydroxamic Acid","Angiotensin I/II (5-8)","Selenomethionine","N-Methyl-a-aminoisobutyric acid","2-Methyl-4-(1H-purin-6-ylamino)butan-1-ol","1-Hydroxyoct-2-enoylglycine","Hydroxyurea","3-Hydroxypicolinic acid","Miglustat","n-Isopropylbenzenesulfonamide","3-Aminoisobutanoic acid","4-(Methylsulfanyl)butan-2-ol","1-Phenylethanol","4-Methylpent-2-enal","Vaccinoside","Phensuximide","L-Homocystine","6-Methyl-5-hepten-2-one","1,2,4-Benzenetriol","4-Methyl-1-phenyl-2-pentanol","4-Hydroxy-l-tryptophan","2-Octanamidoacetic acid","N-decanoylglycine","Cyromazine","LPE(16:1/0:0)","Dimethylglycine","Glutamine","tetrahydrozoline","N-Acetyl-L-phenylalanine","5-Aminoimidazole-4-carboxamide","Citpressine I","14,15-Leukotriene C4(ExC4)","1-(Ammoniomethyl)cycloheaxaneacetate","Bardoxolone","1-hexadecanoyl-2-[(Z)-octadec-9-enoyl]-sn-glycerol 3-(2-aminoethylphosphonate)","1,2,4-Trimethylbenzene","Bicine","Dimethyl fumarate","3-Amino-2-oxazolidone","Amantadine hydrochloride","4-Oxo-4-(pyridin-3-yl)butanal","1,2,3,4,5-Benzenepentol","Tyramine","Propionic acid","D-Kynurenine","1,4,5,6-Tetrahydro-6-oxonicotinic acid","L-ribulose","12-Hydroxydodecanoic acid","Bilirubin (E-E)","Gly-Val","Deanol","2-Hydroxy-2-methylpropanal","Melezitose","2-Acetylpyrrole","3-Hexenedioic acid","1-Chloro-2-methylpropene","(1R,4R,5R)-2-methyl-5-[(2S)-6-methylhept-5-en-2-yl]cyclohex-2-ene-1,4-diol","2-Azaniumyl-2-methylpropanoate","1-Naphthylhydroxylamine","Melanostatin","2-(2,4-dihydroxyphenyl)-3-(3,7-dimethylocta-2,6-dien-1-yl)-5-hydroxy-8-(hydroxymethyl)-8-methyl-4H,8H-pyrano[3,2-g]chromen-4-one","2',3'-Dideoxyinosine","N'-nitrosonornicotine","Indoleacetic acid","Isovaleramide","3-Methylpentan-3-ol","Resolvin E1","Deisopropylhydroxyatrazine","Hydroxyphenyllactic acid","Rhodinyl propionate","N-Lactoylisoleucine","Meprobamate","7-Ethyl-10-(4-N-aminopentanoic acid)-1-piperidino)carbonyloxycamptothecin","Choline","Cotinine methonium ion","PC(8:0/8:0)","Asparagine","2,3-Dihydrobenzofuran","Tromethamine","4,4'-Methylenedianiline","Trp-Pro","5alpha-Androstane-3beta,17beta-diol","Tyrphostin 23","Nicotinic acid","Dimethylurea","5-Hydroxymethyluracil","DL-Methionine","L-Isoleucine","2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid","L-alpha-Aminobutyric acid","trans, trans-3,5-Octadien-2-one","(2-(1-Butoxyethoxy)ethyl)benzene","4-Amino-3-hydroxybutyrate","Novaluron","2-Ethyl-4-hydroxy-5-methyl-3(2H)-furanone","Sedoheptulose 7-phosphate(2-)","2-Furoic acid","Glycyl-L-leucine","1-Methylpyrrolinium","4-Methylthiobutanaldoxime","Solasodine","4-Nitrocatechol","Isonicotinamide","2'-Deoxyadenosine","5-Bromo-3-fluoro-1-methylpyridin-2(1H)-one","Sibutramine","Oxadixyl","6-Methyl mercaptopurine","4-Hydroxyphenylpyruvic acid","Val-Gln","Clonidine","Epsilon-caprolactam","Guvacine","Piperidine","D-Ornithine","L-2-Aminoadipic acid","Tilarginine","2-amino-4-({1-[(carboxymethyl)-C-hydroxycarbonimidoyl]-2-({4-hydroxy-6-[3-(4-hydroxyphenyl)-3-oxoprop-1-en-1-yl]-5-methoxy-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-3-yl}sulfanyl)ethyl}-C-hydroxycarbonimidoyl)butanoic acid","1,4-Naphthoquinone","Spermidic acid","DL-Glutamine","3-Guanidinopropionic acid","1-Nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene","Phosphocholine","1-o-Hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine","Hymecromone","Glycyl-L-phenylalanine","2-Hydroxy-1,4-benzoquinone","Enantio-PAF C-16","Mechlorethamine","1,2-Distearoyl-sn-glycero-3-phosphocholine","2-Methyl-4-phenylbutyraldehyde","N-Isovaleroylglycine","3,3-Dimethylglutaric acid","2-Hydroxy-2-methylbutanenitrile","Stearoylcarnitine","(4-Hydroxy-3-methoxyphenyl)ethanol","Quinoline","Semidehydroascorbic acid","Aspartylysine","2-Methyl-1-methylthio-2-butene","1-O-Hexadecyl-2-arachidonoyl-sn-glycero-3-phosphocholine","6-Hydroxyhexanoic acid","Arecoline","L-Proline","1,2-Didecanoyl-sn-glycero-3-phosphocholine","Phenol","1-Methyl-4-nitroimidazole","LPC(0:0/18:3)","Aminosalicylic Acid","3-Hydroxyanthranilic acid","PE(P-16:0/20:3(8Z,11Z,14Z))","[2-hydroxy-3-[(9Z,12Z)-octadeca-9,12-dienoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate","5-Hydroxyindoleacetic acid","Glucosamine","Dicyclohexylamine","4-(3-Acetamidopropylamino)butanoic acid","1,2,3-Trihydroxybenzene","Piperidine acid","m-Chlorobenzoic acid","Glycine","2-Hydroxyquinoline","2H-Pyran-2-one, tetrahydro-4-hydroxy-4-methyl-, (R)-","1-(1-Ethoxyethoxy)pentane","1-Piperidinecarboxaldehyde","Moupinamide","Melamine","exo,exo-1,8-Epoxy-p-menthane-2,6-diol","Miglitol","Dimethyl tetrasulfide","5-Hydroxytryptophol","h-gamma-Glu-leu-oh","DL-Pantothenic acid","Ethyl acetoacetate","(4-Hydroxy-3-nitrophenyl)acetate","Isoetharine","BURIMAMIDE","Methylthiouracil","Thiaburimamide","(R)-beta-alanopine","Guanosine","2-[(Pyrrolidinium-2-ylcarbonyl)amino]propanoate","Cytochalasin B","DL-Pyroglutamic acid","1,2-Dipalmitoleoyl-sn-glycero-3-phosphocholine","1-O-Palmitoyl-2-O-acetyl-sn-glycero-3-phosphorylcholine","Polyporusterone A","2-Aminoisobutyric acid","Porson","2-Oxo-8-methylthiooctanoic acid","Choline Alfoscerate","Geneticin","L-Homocysteic acid","Cinoxacin","Glu-Phe","N-Acetyl-DL-tryptophan","Pindolol","4-Hydroxy-3-iodophenylpyruvic acid","D-Threitol","N-Acetylthreonine","5-Methyl-2-furancarboxaldehyde","Neryl acetate","1-Methylphenanthrene","Phenethylamine","Nelarabine","Triacetin","1-Isopropenyl-3-isopropylbenzene","Pyroquilon","Diethanolamine","Obacunone","2-Chloroquinoline","1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine","Zafirlukast","Suberylglycine","3-Methylglutaconic acid","MG(18:2/0:0/0:0)","5,5-Dimethyl-1-pyrroline N-oxide","Butyl 4-aminobenzoate","11-Hydroxyhexadecanoic acid","Arg-gly-asp-ser","Nornicotine","L-Dopa","4-Hydroxycoumarin","1-Naphthylamine","[(4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl] phosphono hydrogen phosphate","Cyclohexaneacetic acid","Hypotaurine","3-hydroxy-2-(hydroxymethyl)-2-[(sulfooxy)methyl]propanoic acid","6,7-dihydropyrrolo[2,3-c]azepine-4,8(1H,5H)-dione","N-formimidoyl-L-aspartic acid","2-Dodecenal","Levofloxacin","(R)-3-hydroxybutyrylcarnitine","1-Deoxynojirimycin","Nonadecanoic acid, 1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxohexadecyl)oxy]ethyl ester, (R)-","Metoclopramide","2-Amino-5-oxohexanoic acid","Spermidine","Isofraxidin","S-Phenyl-N-acetylcysteine","LPC(0:0/16:0)","L-Cladinose","6-O-Acetylarbutin","3,8'-Biflaviolin","Phenylbutyrylglutamine","Sulforaphene","(+/-)-8-Hydroxy-5Z,9E,11Z,14Z,17Z-eicosapentaenoic acid","Phenazopyridine","Urocanic acid","LPE(18:0/0:0)","N,N-dimethylarginine","PC(15:0/18:4(6Z,9Z,12Z,15Z))","N-(2-Furoyl)glycine","TRIETHYL PHOSPHATE","Methyl aminolevulinate","Allopregnane-3beta,11beta,17alpha,21-tetrol-20-one","(1S,5R,8R,10S,11R,13R,14S,15S,16R)-7-ethyl-5-methyl-12-methylidene-7-azahexacyclo[7.6.2.210,13.01,8.05,16.010,15]nonadecane-11,14-diol","1,2-di-[(11Z)-eicosenoyl]-sn-glycero-3-phosphocholine","beta-N-Methylamino-L-alanine","N-(9Z-octadecenoyl)-sphing-4-enine-1-phosphocholine","Psicose","Crotyl alcohol","Octanol","Lysergamide","3,3'-Diaminobenzidine","3-Pyridinemethanol","Tetraethylene glycol","[2-[(9Z,12Z)-octadeca-9,12-dienoyl]oxy-3-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate","Astemizole","2-Acetylfuran","4-Nitrophenol","Octadecanamide","2-Hydroxypyridine","Carnitine C2:0","1H-Imidazol-1-ylacetic acid","Creatinine","9-Decenol","Fluchloralin","O-Decanoyl-L-carnitine","3-Aminobutanoic acid","Carnitine isoC4:0","Monomenthyl succinate","4-Aminocatechol","Acetyl-L-carnitine","Levomethorphan","1-O-Hexadecyl-sn-glycero-3-phosphocholine","(+)-Penbutolol","D-Xylonate","Lichenin","5-Aminopentanoic acid","5'-Deoxy-5-fluorocytidine","2-Phenylacetamide","N-Acetylleucine","Oglufanide","Hexaethylene glycol","N-ethylmaleimide","Palmitic amide","6-(2-Carboxyacetyl)oxy-3,4,5-trihydroxyoxane-2-carboxylic acid","Betaine","L-Alanine","2-Methoxy-5-nitroaniline","2-Hexadecenal","Mitoxantrone","1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine","3-Formylsalicylic acid","L-Tyrosine ethyl ester","4-Acetamidobutanoic acid","Pterin","1-Aminocyclopropane-1-carboxylic acid","(2-methyl-3-phenylpropoxy)sulfonic acid","1-Heptanol","PC(18:0/18:2)","Cytidine","1-Stearoyl-2-myristoyl-sn-glycero-3-phosphocholine","Lathyrine","Carvyl acetate","4-(Aminomethyl)benzoic acid","Isoquinoline","Thalsimine","Pyridostigmine","2-Aminoadipic acid","Vecuronium","Narcobarbital","Azelaoyl PAF","2-Nonanone","Misoprostol","Genipin","Octylamine","1-(9Z-tetradecenoyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol","¦Ã-Aminobutyric Acid","3,5-Dimethyl-1-hexyn-3-ol","4-Methylvaleric Acid","7-Nitroindazole","N-Methylalanine","2-Phenylpropanal","Didesmethylsibutramine","Metoprolol","6,7,8-Trihydroxy-2H-1-benzopyran-2-one","N-Palmitoylsphingomyelin","4-Hydroxyphenylglyoxylic acid","Nootkatone","2-[[2-amino-5-(diaminomethylideneamino)pentanoyl]amino]propanoic Acid","3-Penten-2-one","Progesterone","Benzylamine","N-(4-Hydroxyphenyl)glycine","Benzo[b]naphtho[2,1-d]thiophene","N5-methylglutamine","(2r)-3-(Hexadecyloxy)-2-methoxypropyl 2-(trimethylammonio)ethyl phosphate","2-Benzylsuccinic acid","1,2-Dimethoxybenzene","Angiotensin III","Ephedrine","2-Methylvaleric acid","4-Chloroaniline","L-Homoserine","1,2,3,7,8-Pentachlorodibenzo-P-dioxin","Flutriafol","4-Guanidinobutyric acid","p-Synephrine","Glyc-Pro","Phosphoenolpyruvate","3-Aminophenol","Sparfloxacin","Kynurenic acid","4-Vinylguaiacol","LPC(O-16:0/2:0)","(Z)-1-(Methylthio)-5-phenyl-1-penten-3-yne","2,8-Quinolinediol","Esmolol","Methionine","Barbituric acid","p-Coumaryl alcohol 4-O-glucoside","Deisopropylatrazine","Pentostatin","Benzamidine","2-Methyl-3-thioacetoxy-4,5-dihydrofuran","Ethyl hexadecanoate","Met-Met","[(2R)-1-[[(2S)-2,3-dihydroxypropoxy]-hydroxyphosphoryl]oxy-3-(10-methyldodecanoyloxy)propan-2-yl] 22-methyltetracosanoate","Cys-Cys","Rhapontigenin","3-[(4aS,12aR)-2-methyl-1,3,4,5,12,12a-hexahydropyrido[3,4-b]acridin-4a-yl]phenol","2-Amino-6-methoxypurine","1-Butanol","Butenoyl-PAF","3-Methoxytyramine","Neostigmine","Vigabatrin","L-Norleucine","o-Phenylenediamine","1,2-Didecanoylglycerol","Armillarin","Peonidin chloride","N-Ethylacetamide","Niacinamide","1-Acetoxy-2-hydroxy-16-heptadecyn-4-one","6-[(3-Hydroxy-5-methoxyphenyl)methyl]-2-methyl-2,3-dihydropyran-4-one","1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine","L-Homoarginine","Sanguinarine","Ferulic acid","Hemine","2(5H)-Furanone","N-Hydroxy-L-asparagine","3,3'-Dimethylbenzidine","DI(Hydroxyethyl)ether","3-(Methylthio)propionic acid","5-Hydroxymethyl-2-furancarboxaldehyde","Indole-3-propionic acid","Hexylamine","1-Tert-butoxy-2-propanol","4-Hydroxy-3-methoxybenzenemethanol","Tiopronin","D-phenylalanine","Glycine, N-[imino(phosphonoamino)methyl]-N-methyl-","Leu-Enkephalin","Glycylglycine","Aminocaproic acid","Harmine","Triamcinolone diacetate","2,3-Diaminopropionic acid","Phytosphingosine","Vinburnine","N-(Hydroxymethyl)acrylamide","Methacholine","2-Acetylpyrazine","Ethylmethylacetic acid","Isopentenyl pyrophosphate","psi-Pelletierine","Gallic acid","Lenticin","alpha-Hydroxyisobutyric acid","5'-Deoxy-5'-(Methylthio) Adenosine","5-(Methylthio)-2,3-dioxopentyl phosphate","Coumarin","Spermine","Myristic acid","1-[3-(Trifluoromethyl)phenyl]piperazine","Hypoxanthine","Temozolomide","Tetrahydrofurfuryl butyrate","1,2-Dioleoyl-sn-Glycero-3-Phosphocholine","3-Aminosalicylic acid","2-Arachidonoylglycerol","1-Nitroheptane","Cytarabine","N6,N6,N6-Trimethyl-L-lysine","N-Nitrososarcosine","Oxindole","Etilamfetamine","Tropine","Dihydro-2-methoxy-2-methyl-3(2H)-thiophenone","(S)-beta-Aminoisobutyric acid","Deoxyvasicinone","Glycerol tripropanoate","D-Proline","L-Serine","Purine","Lumichrome","2-Pyrrolidinone","Propargite","ISOPRENE","Levonordefrin","1,4-Dihydro-1-methyl-4-oxo-3-pyridinecarboxamide","1-Pentanethiol","Delphinidin 3-sambubioside","LPE(16:0/0:0)","4-(Dimethylamino)butyl carbamimidothioate","2,5-Dimethyl-1,4-dithiane-2,5-diol","Erythorbic acid","Ureidosuccinic acid","(3R,4S)-3-acetamido-4-(diaminomethylideneamino)-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid","Edifenphos","Diphenylpyraline","1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine","PS(16:1(9Z)/22:4(7Z,10Z,13Z,16Z))","xI-Dihydro-2-methyl-3(2H)-thiophenone","2-Aminoethyl dihydrogen phosphate","Cucurbitacin B","N-Methyltyramine","Naphthalene","Glycidol","Dihydrouracil","(R)-1,3-Octanediol","cotinine N-oxide","(E)-6-hydroxy-1-(4-hydroxy-3-methoxyphenyl)tetradec-4-en-3-one","1-(2,4,5-Trimethoxyphenyl)-1,2-propanedione","Pelargonidin chloride","N-(4-Aminobenzoyl)-Beta-Alanine","Proadifen","5-Formyl-2-furancarboxylic Acid","3,4-Dihydroxybenzylamine","Gallocatechol","Digoxigenin bisdigitoxoside","Dimethyl phthalate","xi-3-Methyl-3-cyclohexen-1-ol","Picolinic acid","Penitrem B","Methyl 4-(methylthio)butyrate","Diisobutyl phthalate","2-Phenoxyethanol","Sumiki's acid","(2-Oxo-1,2-diphenylethoxy)sulfonic acid","Piperazine","Furfuryl alcohol","2-Aminobenzimidazole","Pyroglutamic acid","S-Glutathionyl-L-cysteine","Propofol","Pyridoxamine","Dipivefrin","Isopalmitic acid","Succinylacetone","Fludrocortisone acetate","5-Imino-2-methyl-1-cyclopenten-1-ol","Butanal","4-Hydroxy-3-(sulfooxy)benzoic acid","(-)-Globulol","(+/-)-High Proline","4-Azaniumyl-4,5-dihydro-1,2-oxazol-3-olate","(2E)-Decenoyl-ACP","1-Methyl-2-pyrrolidinone","Butyl 3-methylbutanoate","9-nitro-9E-octadecenoic acid","4-Allyl-2,6-dimethoxyphenol","Dibutyl phthalate","1-Palmitoyl-2-myristoyl-sn-glycero-3-phosphocholine","Glucurolactone","Norsalsolinol","Tranexamic Acid","Arcaine","3-Methylglutarylcarnitine","Terbutaline","Phenazine-1-carboxylic acid","D-Alanine","Indole-3-acetamide","Allyl methyl sulfoxide","D-Homocysteine","N-Nitroso-pyrrolidine","Benzaldehyde","3,7-Dimethyl-3-octanol","1-Oleoyl-2-palmitoyl-sn-glycero-3-phosphocholine","Histamine","2-Pentylthiophene","Clopidol","6-Dimethylaminopurine","7-Deoxyloganetic alcohol","Poloxamer-188","VERBENONE","N-Furfurylformamide","2-[(2-Amino-3-hydroxypropanoyl)amino]-3-sulfanylpropanoic acid","LPC(14:0/0:0)","Methionine sulfoxide","Normetanephrine","Allantoic acid","Ginkgolic acid","PC(O-16:0/O-1:0)","2-Amino-2-methyl-1,3-propanediol","2-Aminobenzoic acid","Epinephrine","4-Chloro-L-phenylalanine","Albizziin","(2-(Dimethylamino)ethyl)phosphonic acid","Carnitine-2-methyl-C4","2,2,5,7,8-Pentamethyl-6-chromanol","1-pentadecanoyl-2-(11Z,14Z-eicosadienoyl)-glycero-3-phosphocholine","Win VI","Norvaline"],"additional_accession":[]},"is_claimable":false,"name":"Exploring the Effects of Different Exercise Modalities on Skeletal Muscle Function in High-Fat Diet-Induced Obese Mice Based on Gut Microbiota and Metabolomics","description":"Exploring the Effects of Different Exercise Modalities on Skeletal Muscle Function in High-Fat Diet-Induced Obese Mice Based on Gut Microbiota and Metabolomics
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