MetaboLights

application/xml

ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS13992/m_MTBLS13992_LC-MS_alternating_reverse-phase_metabolite_profiling_v2_maf.tsvftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS13992/s_MTBLS13992.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS13992/i_Investigation.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS13992/a_MTBLS13992_LC-MS_alternating_reverse-phase_metabolite_profiling.txtprimary200OKftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS13992For metabolite identification, the accurate mass of each peak (mass error < 10 ppm) was matched with the Human Metabolome Database (HMDB), Metlin, and KEGG databases; the MS/MS fragmentation patterns were further compared with the database spectra to confirm the structure of metabolites. Only metabolites with a matching score ≥80 and a false discovery rate (FDR) < 0.05 were considered reliably identified.MetaboLightsPublicLiquid Chromatography MS - alternating - reverse-phaseThe chromatographic separation was performed using a Thermo Scientific UltiMate 3000 HPLC system (Parameter Value[Chromatography Instrument]: Thermo Scientific UltiMate 3000 HPLC) equipped with an autosampler (Parameter Value[Autosampler model]: Thermo Scientific UltiMate 3000 Autosampler). A Waters ACQUITY UPLC HSS T3 column (Parameter Value[Column model]: Waters ACQUITY UPLC HSS T3, 100 mm × 2.1 mm, 1.8 μm) was used for metabolite separation, which is suitable for non-targeted metabolomics due to its excellent separation performance for polar and non-polar metabolites. A matching guard column (Parameter Value[Guard column]: Waters ACQUITY UPLC HSS T3 Guard Column, 20 mm × 2.1 mm, 1.8 μm) was installed to protect the analytical column and improve detection stability. Mechanistic profiling of Bifemetstrobin against the tea anthracnose pathogen and candidate evaluation of an amine oxidase target.Guizhou Universityxinpeng zhangmyceliummass spectrometry assayFor metabolite extraction, the fungal samples were rapidly frozen in liquid nitrogen to quench metabolic activity, ground into fine powder, and extracted with a mixture of methanol:water (4:1, v/v) under ice bath conditions; the extract was centrifuged at 12,000 rpm for 15 min at 4°C, and the supernatant was filtered through a 0.22 μm organic membrane for subsequent LC-MS analysis.Glomerella cingulatahttps://www.ebi.ac.uk/metabolights/MTBLS13992Xinpeng Zhang. Guizhou University. zhangxinpeng175@163.com.Raw LC-MS data were processed using PeakView 2.2 software (SCIEX) for peak extraction, peak alignment, deconvolution, and normalization to obtain a matrix of metabolite peaks with retention time, m/z value, and peak intensity. The processed data were then subjected to multivariate statistical analysis (including principal component analysis (PCA) and partial least squares discriminant analysis (PLS-DA)) to screen for differential metabolites between the EC30 treatment group and the CK group.Treatmentzhangxinpeng175@163.comSamples were collected from mycelia of Glomerella cingulata treated with bifemetstrobin at EC30 dose for 24 hours, with 6 biological replicates in the treatment group (EC30) and 6 biological replicates in the control group (CK)MetabolomicsantifungalbifemetstrobinGlomerella cingulata peptideantifungalbifemetstrobinGlomerella cingulata peptideMetabolite detection was carried out using a TripleTOF 6600+ high-resolution tandem quadrupole-time-of-flight mass spectrometer (SCIEX, Massachusetts, USA) coupled with the HPLC system. The key mass spectrometry parameters were set as follows: Parameter Value[Instrument]: SCIEX TripleTOF 6600+; Parameter Value[Scan m/z range]: 50-1500 m/z; Parameter Value[Ion source]: Electrospray Ionization (ESI); Parameter Value[Mass analyzer]: Quadrupole-Time of Flight (Q-TOF).SesarteminCarboprost TromethamineDacarbazinegamma-Aminobutyric acidGuaiacolEctoineOctadeca-2,4-dienoic acidMethyl nicotinatePA(20:4(5Z,8Z,11Z,14Z)-OH(20)/10:0)Heliannuol CKetoleucineReserpineFlufenacet(2S,3R,4R)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acidPropoxyphene2,6-Dimethoxyphenol5-MethylnonanoylcarnitinePhenylalanylproline2-Ethyl-1-hexanol sulfate3-ethylphenyl SulfateInulineN-Arachidonoyl CysteineGuanosine 2'-monophosphate2,3-Dihydroflavon-3-ol4-Hydroxybenzaldehyde4-Methylcoumarin(R)-RhazinilamCyclohexylaminePC(P-18:1(11Z)/15:0)Bafetinib9-HpodeEliglustatPA(18:4(6Z,9Z,12Z,15Z)/20:5(5Z,8Z,11Z,14Z,17Z))2'-C-Methylguanosine6-Methylquinoline[7]-Paradol2-Hydroxy-6-tridecylbenzoic acidDodeca-2,5,8-trienoylcarnitine2,6-DiisopropylnaphthaleneLysoPC(14:0/0:0)4-(1,1,3,3-Tetramethylbutyl)-phenolSM(d17:1/PGJ2)EntospletinibPC(22:5(4Z,7Z,10Z,13Z,19Z)-O(16,17)/2:0)L-Glyceric acidN-Methyl-L-prolineN-Acetylneuraminic acidAcifluorfenArterolaneGlyceollin IVPantothenic acidHeteroflavanone AHeteroflavanone C1,7-bis-(4-Hydroxy-3-methoxyphenyl)-heptane-3,5-diolVindolineNookatoneGlyceraldehydeIsolinderanolide2,6-Dimethoxy-4-(1-propenyl)phenol1-Hydroxyanthraquinone(2S,2'S)-Pyrosaccharopineall-trans-Hexaprenyl diphosphatePonticaepoxideAmitrolePGP(i-12:0/i-24:0)DG(18:3n6/0:0/18:4n3)2,3,4-TrichlorophenolOctaethylene glycol2,2,4,4,-Tetramethyl-6-(1-oxopropyl)-1,3,5-cyclohexanetrioneAminoadipic acidCer(d18:1/LTE4)L-3-Cyanoalanine4-Methoxybenzaldehyde1-(2-Furyl)butan-3-oneAlprazolamO-DemethylmetoprololOxidized glutathioneLysoPC(16:1/0:0)tricoumaroyl spermidinePrenylamineIsovalerylcarnitineSM(d16:2(4E,8Z)/22:6(5Z,8E,10Z,13Z,15E,19Z)-2OH(7S, 17S))SM(d18:0/20:3(8Z,11Z,14Z)-2OH(5,6))CubebininMuzanzageninIsocitric acidDihydroisorhamnetincis-Vitamin K1Furanone APhenylalanylglycineL-CarnitineVenlafaxine13-OxoODEMethazolamideLidoflazine4-Fluorobenzoic acidhept-3-enedioic acidAdenosinePC(16:0/18:1(9Z))Pregn-4-en-20-yn-3-one, 17-hydroxy-2-(hydroxymethyl)-, (2alpha,17alpha)-Dihydroactinidiolide(9Z,11E,13Z)-octadeca-9,11,13-trienoic acid9-OxoODEN-Stearoyl Asparagine2,4-Hexadien-1-olMethyl [6]-paradolPA(18:3(6Z,9Z,12Z)/18:3(6Z,9Z,12Z))Cloxazolam, (R)-Pro-Ile2-hydroxymethylolanzapineSM(d18:0/20:4(6Z,8E,10E,14Z)-2OH(5S,12R))Linoleic acidPA(20:4(7E,9E,11Z,13E)-3OH(5S,6R,15S)/18:3(6Z,9Z,12Z))Occidentoside3-hydroxyicos-11-enoic acidRetusin5-ethyl-5-methyl-2,4-oxazolidinedioneFructosyl-lysine6-DecanolideN-[1-[4-[(4-Pyrimidin-2-ylpiperazin-1-yl)methyl]phenyl]cyclopropyl]acetamide4alpha-PhorbolSuccinaldehyde3-MethylthiofentanylAlanyltryptophanUridine diphosphate glucoseArginylphenylalaninePC(24:1(15Z)/6 keto-PGF1alpha)1,3,5-TrioxaneEmeriamineMizolastinePivmecillinamGibberellin A9Caudatin(¡À)-2-Hydroxy-4-(methylthio)butanoic acid9,12,13-TriHOMEalpha-IoneneN-UndecanoylglycineN-Benzoyl-3-phenylisoserine methyl ester8-HydroxycarvedilolLysinetrans-Cinnamic acidN(omega)-Hydroxyarginine(9E,12Z)-10-Nitrooctadeca-9,12-dienoylcarnitineSelpercatinibSimulansamideAlanylhistidine(9R,10S,12Z)-9,10-Dihydroxy-8-oxo-12-octadecenoic acidN-Lauroyl LeucineRet-P-manPC(14:0/20:0)Quinmerac1-Methylnicotinamide1-Isopropyl-2-methylbenzeneDG(15:0/20:4(5Z,8Z,11Z,14Z)-OH(20)/0:0)(8R,9R,10R,13S,14S)-17-Ethynyl-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,7,17-triolBetulafolienetriol(S)-NeomammeinAnnocherine BAdapaleneDL-Norleucine1-(1-Acetyl-piperidin-4-yl)-3-adamantan-1-yl-ureaPC(P-16:0/20:3(6,8,11)-OH(5))Uridine 5'-monophosphatePA(8:0/a-13:0)(5Z)-13-Carboxytridec-5-enoylcarnitineAmbronidePC(DiMe(9,3)/LTE4)11-hydroxyhexadeca-6,12-dienoic acidVeratramineDillanol13-HPODE(1-)BenzophenoneRanolazine6-((3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy)-N-methyl-3-pyridinecarboxamide6beta-HydroxydexbudesonideGlucose 6-phosphateAcrimarine I7-beta-HydroxyepiandrosteronePE(DiMe(9,3)/PGF1alpha)Indole-3-carboxaldehydeO-Desmethylverapamil (D-703)MenaquinolCichoralexinp-FluorofentanylCarbetapentane1H-Imidazole-1-acetic acidAdrenosteroneN-[4-(Benzylamino)-3-cyanoquinolin-2-yl]-4-methoxybenzamideLysoPC(17:0/0:0)(4R,5S,7R,11x)-11,12-Dihydroxy-1(10)-spirovetiven-2-one 12-glucosideEstriol-16-GlucuronidePhenyl-AlanineGlabrin ALysoPE(18:0/0:0)(12Z)-10-hydroxyoctadec-12-enoic acidPIP(16:2(9Z,12Z)/20:3(8Z,11Z,14Z)-O(5,6))CafestolDiphenidolChenodeoxycholic acid glycine conjugateGlyoxylic acidN-Hexadecanoylpyrrolidine3-Methylnonanedioylcarnitine(8R,9S,13S,14S)-3-Hydroxy-13-methyl-1-octadec-9-enoyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-onePA(18:3(6Z,9Z,12Z)/18:2(10E,12Z)+=O(9))2,5-Dihydro-2,4,5-trimethyloxazolePropylbenzeneProstaglandin J2ThymineN-[[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[5,4-d]pyridin-7-yl]methyl]piperidin-4-aminedesmethylastemizoleDynorphin A (6-8)Theaspirone ADTDP-alpha-D-glucose(2-)Testosterone Propionate(1R)-trans-Phenothrin(1S,2R,4R,8S)-p-Menthane-2,8,9-triol 9-glucoside6-hydroxytrideca-8,10-dienoic acidGoshonoside F4L,L-Cyclo(leucylprolyl)Maltolhex-3-enedioic acid(1(10)E,4E,6a,9b)-9-(2-Methylbutanoyloxy)-1(10),4,11(13)-germacratrien-12,6-olide2-Hydroxyundec-2-enoylcarnitine2'-Hydroxy-4',6'-dimethoxychalcone3a,6b,7b,12b-Tetrahydroxy-5b-cholanoic acidPyridazine-3,6-dioltrans-5,6-Dihydro-5,6-dihydroxy-7,12-dimethylbenz[a]anthracenePGP(18:1(11Z)/18:1(11Z))IsobutylpropylaminePS(20:4(5Z,8Z,11Z,14Z)/22:6(5Z,7Z,10Z,13Z,16Z,19Z)-OH(4))8-Amino-7-oxononanoic acid9,10-Epoxyoctadecanoic acidMarshdine1H-Benzimidazole-2-carboxamide, 1-(4-methoxybutyl)-N-(2-methylpropyl)-N-((3S,5R)-5-(4-morpholinylcarbonyl)-3-piperidinyl)-Triphasiol4-AminophenolPyrralineN-Stearoyl GlutamineAncistrocladineMethyl 15-cyanopentadecanoateEthyl isopropyl sulfideDiethyl succinateHematoporphyrinAjmalicinePA(10:0/13:0)PC(14:0/20:3(5Z,8Z,11Z)-O(14R,15S))9-Methylxanthine5-hydroxytrideca-8,11-dienoic acid1-Methylguanosine3'-Hydroxy-4',5',7,8-tetramethoxyflavone7-Demethyltangeretin2-Naphthalenesulfonic acid16-Hydroxy-10-oxohexadecanoic acidParomomycin ILysoPA(i-12:0/0:0)Penicillin KPyruvic acidMeclizineDiisopropylamineCetiedilAdrenoyl ethanolamide2,3,5,6,8,8a-Hexahydro-2,5,5,8a-tetramethyl-7H-1-benzopyran-7-oneBenzidine2'-Epi-Perindopril, (2'R)-CocculineMethacrylamide2-Lysophosphatidylcholine2-[(2-Amino-2-oxoethyl)-[(2S)-2-[(2-amino-2-oxoethyl)-(carboxymethyl)amino]propyl]amino]acetic acidDopaminePhorone A17-Hydroxylinolenic acidTamarixetinN,N-DimethylethylamineBenzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-Tyr-ile-gly-ser-argPolyoxyethylene sorbitan monooleateD-Mannose 1-phosphateL-Valine2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenolSinapic acidRopivacaine7-hydroxytrideca-9,11-dienoic acidTrihydroxybutaneDiaveridineTetradecenoylcarnitineIsopropenyl acetateGlucosereductone3-Methyl-2-(3-pyridyl)-1-indoleoctanoic acidDihydro-4-mercapto-3(2H)-furanoneFenbendazoleGlycyl-Isoleucine(3-Aminopropyl)(n-butyl)phosphinic acid2-NitropropaneTrimipramineDipipanonePyrodoneFuranojaponinMulberrofuran ADoramapimod12-oxo-PDAFragransin C1Mulberrofuran TDemethoxyfumitremorgin CAdipic acidDephospho-CoAN-lactoyl-TryptophanN-MethylolpentamethylmelamineMyricanone[(3S,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl] octadec-9-enoateAlpha-LactoseTaurochenodesoxycholic acidParakmerin APC(2:0/22:6(5Z,8E,10Z,13Z,15E,19Z)-2OH(7S, 17S))2-ImidazolidoneDG(15:0/20:4(5Z,8Z,11Z,13E)+=O(15)/0:0)Menthol glucuronideForetinibEriobofuranIsoleucineDextromoramide3-hydroxytrideca-5,7-dienoic acidPG(LTE4/i-13:0)Canrenone2-Methylhippuric acid(12E)-9-hydroxyoctadec-12-enoic acidPC(14:1(9Z)/22:6(5Z,7Z,10Z,13Z,16Z,19Z)-OH(4))Citraconic acidFumarycarnitine2-Aminodipyrido[1,2-a:3',2'-d]imidazoleRizatriptanSolasodiene6-HydroxyketamineN-Acetyl-L-phenylalanineDicaffeoylputrescine(9Z,12Z)-6-hydroxyoctadeca-9,12-dienoic acidFenhexamidPA(16:0/14:1(9Z))IsomurrayazolineAdenosine 3',5'-diphosphate4-Hydroxycinnamic acidSaccharopineN-((2,2-Dimethyl-2,3-dihydro-benzofuran-7-yloxy)ethyl)-3-(cyclopent-1-enyl)benzylamine1,10-PhenanthrolineBenzeneacetic acid, 4-(2-(diethylamino)-2-oxoethoxy)-3-ethoxy-, propyl esterXylulose 5-phosphateCrenolanibtetradeca-3,5,7-trienoic acid1,2-Dihydro-1,1,6-trimethylnaphthaleneIsokessane6-Methyl-5-hepten-2-one propyleneglycol acetal[3-[2,3-Dihydroxypropoxy(hydroxy)phosphoryl]oxy-2-hydroxypropyl] hexadecanoate(S)-Methylmalonic acid semialdehyde2-(Diethylamino)ethyl 4-amino-5-chloro-2-methoxybenzoate3, 5-Tetradecadiencarnitine7-oxooctanoic acidPG(i-17:0/20:4(6E,8Z,11Z,14Z)+=O(5))3-Hexenedioic acidHomochlorcyclizine7,8-Dehydroastaxanthianthin11-(3-Pentyloxiran-2-yl)undec-9-enoic acid4-[(E)-2-(7-Heptoxy-4,4-dimethyl-1,1-dioxo-2,3-dihydrothiochromen-6-yl)prop-1-enyl]benzoic acidOctadeca-2,4,6,8-tetraenoic acid(2'E,4'Z,8E)-Colneleic acidSuccinic acid semialdehyde4-hydroxyoct-6-enoic acidKynurenine[(2R,5R)-5-(6-Aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphateTyrphostin AG 1296Salicylic acid(-)-2-DifluoromethylornithinePipereicosalidine10-Acetoxytoxol(8E,12Z)-10-hydroxyoctadeca-8,12-dienoic acidManidipineKetamineN-[2-(Dimethylamino)ethyl]-N-methyl-4-[({4-[4-morpholin-4-yl-7-(2,2,2-trifluoroethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]phenyl}carbamoyl)amino]benzamide(S)-4-(4-Methylphenyl)-2-pentanone1,4-Benzodioxin-2(3H)-oneCholine(3b,6b,8a,12a)-8,12-Epoxy-7(11)-eremophilene-6,8,12-trimethoxy-3-olPE(DiMe(9,3)/6 keto-PGF1alpha)PseudoiononeDodeca-2,4,6-trienoylcarnitine(1R,3S,4S)-1,8-Epoxy-p-menthan-3-ol glucoside2,3-DihydrobenzofuranD-TyrosinePanaquinquecol 1BicyclomahanimbicineRhusflavanoneNicotinic acidGentian Violet2-hydroxyacrylic AcidSM(d16:1/20:3(8Z,11Z,14Z)-2OH(5,6))(E)-8-(3,4-Dimethoxystyryl)-7-methyl-1,3-dipropylxanthineNandroloneTributyl Phosphate(2S)-N-[(2S)-1-[Acetyl-[(2S)-1-oxohexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-amino-4-methylpentanamide12,13-EpOMEBetulinGlycerol trihexanoate2-[4,6-Bis(2,4-dimethylphenyl)-1,3,5-triazin-2-yl]-5-(octyloxy)phenoltrans-Allo-ocimene(2R,3S)-1-[(7-Methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-(propan-2-ylamino)butan-2-oldodeca-4,6,8-trienoic acidSucrose laurateCadalene3,5-DihydroxydodecanoylcarnitineD-LysineDimethyl sulfoxideL-Aspartic acidIsohumulinone A2,2,6,7-Tetramethylbicyclo[4.3.0]nona-1(9),4-diene-7,8-diol(2E)-undec-2-enedioic acidLeucineCitramalic acidBiperiden3-chlorobenzaldehyde(9Z,11E,13E,15Z)-4-Oxo-9,11,13,15-octadecatetraenoic acid2-Acetyl-3,5-dimethylfuranCasokefamidep-Aminobenzoic acidEthyl 3,4-dihydroxybenzoateDethiobiotin3,4,5-Trimethoxycinnamic acid10-Hydroxy-8-nor-2-fenchanone glucosideIndole-3-carboxylic acidChlorcyclizinePE(P-18:1(9Z)/20:0)MestranolAritminaPA(18:1(12Z)-O(9S,10R)/i-20:0)LifibrolpyroglutamylprolineTryptophyl-AlanineCDPCarnocin U I49Methyl pyruvateN-AcetylvalineCDP-DG(i-12:0/20:3(8Z,11Z,14Z)-O(5,6))m-Aminobenzoic acid15(S)-Hydroxyeicosatrienoic acidPholcodineMusanolone CLinolenelaidic acidOxoglutaric acid4'-Hydroxy-5,6,7,8-tetramethoxyflavonePhytyl diphosphate(12Z,15Z)-10-hydroxyoctadeca-12,15-dienoic acidDimethindeneBenzoyleneureaQuinocetoneNictindolePirsidomineMesaconic acid3-hydroxyundecanoic acidLeucinic acid1,1,1-TrifluoroethanePibenzimolDG(18:1n9/0:0/18:3n6)Aucubin(10E,12Z)-9-HODE4-hydroxytetradecanedioic acidGlechomafuran1,2,3-TrihydroxybenzeneButyrylcarnitine2-N,N-Di-n-propylamino-4,7-dimethoxyindanPA(18:2(9Z,12Z)/20:2(11Z,14Z))AnhydrocinnzeylanolLiensinineOleic acidBismahanineEstriolAlanyl-Histidine(3beta,23E)-3-Hydroxy-27-norcycloart-23-en-25-oneUridine diphosphate-N-acetylglucosamine5-Hydroxytryptophol(8E,15E)-1,8,15-Heptadecatriene-11,13-diyneGlycitein(4-Methoxynaphthalen-1-yl)(1-pentyl-1H-indol-3-yl)methanoneVersalide2-Methylglutaric acidPA(22:6(4Z,8Z,10Z,13Z,16Z,19Z)-OH(7)/2:0)Cyclo(L-Phe-L-Pro)2-(3-Methylphenyl)-1,3-dioxan-5-olDiisopropyl etherpyrrolo[2,1-c][1,4]benzodiazepine3'-Hydroxyhexobarbital1-Acetylcyclohexyl acetateDG(18:3n6/0:0/18:3n3)3-hydroxystachydrinePC(16:1(9Z)/20:4(6E,8Z,11Z,14Z)-OH(5S))Eudesmic acidGuanosineSinapyl alcoholTrimethoprimDL-ProlineN1,N5,N10,N14-Tetra-trans-p-coumaroylspermine1-Hydroxycarvedilol3-Sulfinylpyruvic acidDG(18:3n6/0:0/18:3n6)KetotifenMarasmen-3-oneBenzyl 6-O-beta-D-apiofuranosyl-beta-D-glucosideProlylphenylalanineN-methylhydroxyprolineHexadecanedioic acid1,4-Dioctyl sulfosuccinic acidPA(18:2(9Z,12Z)/18:3(6Z,9Z,12Z))2-Hexenyl acetate1,N6-EthenoadenineIsorhynchophylline(2E,6E)-2,6-NonadienalNorbicycloekasantalal6-beta-D-Glucopyranosyl-4',5-dihydroxy-3',7-dimethoxyflavoneLotusineSumaroteneMasitinib2,2,7,7-Tetramethyl-1,6-dioxaspiro[4.4]nona-3,8-dienePindolol11,12-Dimethoxy-8,11,13-abietatrien-20,7-olideIndole-3-carbinolN-Acetyl-Leuent-Epicatechin-(4alpha->8)-ent-epicatechin 3'-gallateCrispaneIsoketocamphoric acidPuromycinPA(a-17:0/20:3(8Z,11Z,14Z)-2OH(5,6))LysoPI(16:0/0:0)5-Androstene-3b,16a,17a-triolEuglobal Ia13-Hydroxymethylglutaric acidTetrahydrogestrinoneSM(d16:2(4E,8Z)/20:4(7E,9E,11Z,13E)-3OH(5S,6R,15S))GalactitolEthylene carbonate3-Methylglutaconic acidLysoPA(22:4(7Z,10Z,13Z,16Z)/0:0)N-Docosahexaenoyl IsoleucinePGP(18:0/18:1(9Z))(-)-QuebrachaminePC(22:6(4Z,7Z,11E,13Z,15E,19Z)-2OH(10S,17)/2:0)Tryptophyl-ProlineN-LactoylvalinePhenylpyruvic acid7-Ethyl-3,6-dihydro-1,4-dimethylazulene3-(6-(Dimethylamino)-4-methylpyridin-3-yl)-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-amine8-Hydroxy-1-methoxy-3-methylanthraquinoneDodecyl gallateLysoPA(i-20:0/0:0)GlycylprolineCortexoloneTriethylamine2,5-DimethylstyreneBrexpiprazoleTsibulin 22,3-dihydroxy-3-methylvalerateSphondin2-Aminonaphthalene7-hydroxygranisetron5-HydroxyemedastineSenkyunolide N17-(3-Pyridyl)-5,16-androstadien-3beta-acetate5,7,3',4'-Tetrahydroxyflavanone 7-alpha-L-arabinofuranosyl-(1->6)-glucoside2-Dodecylbenzenesulfonic acid5b-Cholestane-3a,7a,12a,25,26-pentolTrimetazidineMilciclib(9Z,11R,12S,13S,15Z)-12,13-Epoxy-11-hydroxy-9,15-octadecadienoic acid4,5-Epoxy-11(13)-guaien-12,8-olideTrimethyl Phosphate(1S,2S,4R)-1,8-Epoxy-p-menthan-2-ol glucosideGlutamic acid3-Nonyl-1H-pyrazoleNefazodoneGDP-glucoseDihydrocapsiate2-Amino-5-phenylpyridineGalactonic acid(ent-16betaOH)-16,17-Dihydroxy-9(11)-kauren-19-oic acidPE(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))Ginsenoside Rg63-HydroxyfluoreneOctadecanamide3-Hydroxyadipic acid[4]-ShogaolPC(P-16:0/PGJ2)Kessyl glycolEncainide1-Ethyl-2-pyrrolidinone3,17,20-TrihydroxypregnaneOrphenadrine17-Iodoheptadecanoic acid5-Aminopentanoic acid2-Phenylacetamide5-(3-Methyl-5-pentylfuran-2-yl)pentanoylcarnitine12-KETEOxolan-3-one9-(3-Methyl-5-pentylfuran-2-yl)nonanoylcarnitine(1,10,11,12,14,23-Hexahydroxy-6,10,19-trimethyl-24-oxa-4-azaheptacyclo[12.12.0.02,11.04,9.015,25.018,23.019,25]hexacosan-22-yl) 3,4-dimethoxybenzoateEtidocaineN-a-Acetyl-L-arginineGolvatinibLinoleoyl ethanolamide14,19-DihydroaspidospermatineGuanosine diphosphate mannosealpha-CephalinAcetal RItaconic acidGlycerophosphoric acidL-AlaninePA(18:1(11Z)/18:2(9Z,12Z))MitoxantroneErythroskyrinPA(16:0/18:3(6Z,9Z,12Z))4-Acetamidobutanoic acidXanthylic acidCariporideFloionolic acid2-PropylthiophenePipernonalineRibavirin monophosphate(ent-2alpha,3beta,15beta,16beta)-15,16-Epoxy-2,3-kauranediol5,7-Dihydroxy-3',4',5'-trimethoxyflavone13(S)-Hydroperoxylinolenic acid6-Amino-4-(4-phenoxyphenylethylamino)quinazolineIsoquinolineBesifovirRhodamine B9,10-Epoxyoctadecenoic acidTetrahydrofurfuryl disulfideSucrose monolaurateGemcabenePG(a-17:0/PGE2)Endomorphin-1SulindacPhenazocineTemarotenePhenethyl decanoateThymolphthalein2,9-Dimethyl-2,9-diazatricyclo[10.2.2.25,8]octadeca-5,7,12,14,15,17-hexaene-3,10-diol, 9CI(5E,8E,11E)-hexadeca-5,8,11-trienoic acidPA(18:2(9Z,12Z)/18:0)trans-4-Hydroxycyclohexylacetic acidTrideca-1,11-dien-3,5,7,9-tetraynPC(18:1(9Z)/18:2(6Z,9Z))2-Amino-3-methylimidazo[4,5-f]quinolineValine-betaxanthinDecylubiquinoneGrossamideDIBOA tetrahexose2-MethylimidazolePS(16:0/6 keto-PGF1alpha)7-(4-Hydroxy-3-methoxyphenyl)-5-methoxy-1-phenyl-3-heptanoneLactic acidGallopamilRilpivirine3-Oxo-12,18-ursadien-28-oic acidbeta-Solanine5-Thymidylic acid2-Ethylhexyl 4-(dimethylamino)benzoate2-Methylpyrrolidine4'-Hydroxyflurbiprofen(1beta,2beta,5beta)-p-Menth-3-ene-1,2,5-triolNicaraven1,11-Undecanedicarboxylic acidEnalaprilTrioxifene3-oxododecanoylcarnitinePC(14:1(9Z)/LTE4)3-oxodecanoylcarnitinePA(2:0/18:3(10,12,15)-OH(9))(8R,9S,13S,14S,17S)-17-Benzyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol(2Z)-2-Morpholin-4-yliminoacetonitrileAjmalineN-Linoleoyl GABAbeta-Alanine2-Hydroxyadipic acidPiplartineGitoxinDihydroptaeroxylin2-HydroxyfluoreneCastanosperminebergeninStyrene Oxide2,3-DihydroxypyridineIsoleucyl-IsoleucineChloropreneGemfibrozilStyrene2,4-dimethylpentan-3-amineLevobunolol7-FormyldehydrothalicsimidineCarbinoxamineDehydropinifolic acid4-HydroxyprolineRibosylzeatin phosphate(S)-Hexahydropyrrolo[1,2-a]pyrazine-1,4-dioneN,N-Dimethylbutylaminealpha-ChaconineDopexamineNestoroneQuinacainolRosmaridiphenolEicosa-11,14,17-trienoic acidErgocornineMaleic acid homopolymerPC(P-16:0/20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15))2-(2-Butoxyethoxy)ethanol4-Methyl-2-pentyl-1,3-dioxolaneN-AllylglycinePhosphateN-Palmitoyl Glutamine3,4-DihydroxydodecanoylcarnitinePA(a-13:0/20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15))Ferulic acidVesatolimod6,11-Dihydroxy-2,2-dimethylpyrano[3,2-c]xanthen-7(2H)-one7-Isopropyl-5-methylbicyclo[2.2.2]oct-5-en-2-onePyrroline1-Methyl-1,3-cyclohexadienePS(14:0/16:1(9Z))(5alpha,8beta,9beta)-5,9-Epoxy-3,6-megastigmadien-8-olHexylamineTazololPC(P-18:0/20:4(6E,8Z,11Z,14Z)+=O(5))LysoPA(0:0/18:1(9Z))L-prolinamideLysoPC(18:3(6Z,9Z,12Z)/0:0)4-oxooctanoic acidAurantiumalCycloartomuninAminocaproic acidXanthotoxol3-hydroxytrideca-6,9-dienoic acid2,2':5',2''-Terthiophene4-Dodecylbenzenesulfonic AcidO-(13-Carboxytridecanoyl)carnitineLysoPC(18:2/0:0)PC(14:0/22:6(5Z,7Z,10Z,13Z,16Z,19Z)-OH(4))3-Hydroxytetradecanoic acidBenzyl nicotinate9,10-Dihydroxystearic acidArachidonoyl SerinolLevamisoleResmethrinImidazolone4-Methoxy-3,3',5-trihydroxybibenzylN(5)-AcetylornithineMyristic acidPA(18:2(9Z,12Z)/18:2(9Z,12Z))1-Lyso-2-arachidonoyl-phosphatidate3-[4-[(E)-2-[6-(Dibutylamino)naphthalen-2-yl]ethenyl]pyridin-1-ium-1-yl]propane-1-sulfonateBuforminBergaptolPhenyllactic acidBetaxololgamma-L-Glutamyl-L-pipecolic acid9-Oxohexadecanoic acidalpha-SolanineGardenin BN-[(1R)-1-(3-Methoxyphenyl)ethyl]-3-phenylpropan-1-amine3-methylheptadecanoic acidLysoPA(0:0/16:0)ResveratrolFlavinatVomifoliolOphthalmic acid3-hydroxyicosanoic AcidNafoxidineFosphenytoiny-MorphineZankiren(1xi,3xi)-1,2,3,4-Tetrahydro-1-methyl-beta-carboline-3-carboxylic acidPorphyceneEnoxacinAdenine2-((2-Chloroethyl)ethylamino)ethanolHovenitin ICholine sulfateBenzamide, 3-(3-((2-(3,4-dihydroxyphenyl)ethyl)amino)butyl)-Plantaricin BNPE(22:0/P-16:0)LysoPC(16:0/0:0)DiisopropylphosphateIsobutyric acidTriethyl Phosphate3-(3,4-Dihydroxyphenyl)-2-methoxypropionic acidD-Lactic acid2-(4-Methyl-5-thiazolyl)ethyl isobutyratePurineNonanal propyleneglycol acetalVitacoxib2-Phenylethanol glucuronideCDP-DG(i-14:0/20:3(8Z,11Z,14Z)-O(5,6))QuinacrineDihydroxyacetonePromethazineRiesling acetalCholic acidArachidonic acidProtocatechuic acidPC(2:0/20:3(6,8,11)-OH(5))5-(2-Furanyl)-3,4-dihydro-2H-pyrroleCarnosolPA(16:1(9Z)/15:0)Cristacarpin1-(2-Hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-oneHexahydropyrrolo[1,2-a]pyrazine-1,4-dione3-oxoundecanoic acidEthylmalonic acidN-Oleoyl phenylalanineN-(1-Deoxy-1-fructosyl)leucinePG(5-iso PGF2VI/i-19:0)Rhodinyl phenylacetateAllocholic acidPC(P-16:0/20:4(6Z,8E,10E,14Z)-2OH(5S,12R))N-[2-(3,4-Dimethoxyphenyl)ethyl]-3,4-dimethoxycinnamic acid amide4-Hydroxybenzoic acidPA(18:3(6Z,9Z,12Z)/18:0)(10E,12Z)-Octadecadienoic acid2-(Carboxymethylamino)-3-methylbutanoic acid13-HOTE4-hydroxytrideca-6,8-dienoic acidMG(18:2(10E,12Z)+=O(9)/0:0/0:0)TheophyllineQuinupraminePC(14:0/14:0)MotesanibN-LactoylleucineD-Malic acidProadifen(S)-3-Ethylidenehexahydropyrrolo[1,2-a]pyrazine-1,4-dione2-Hydroxyvaleric acidAcetylenedicarboxylic acidTetrazepamTuranose2-AminobiphenylPicolinic acid5,6,7,8-Tetrahydroxy-3',4'-dimethoxyflavonePenitrem E2-Hexaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinolTridemorphEthyl carbamatePyroglutamic acidMannitol1,3,5-TrihydroxybenzeneEcdysone8,9-DiHETrEEpoxyoxophoroneN-MethylnicotinamidePE(18:2(9Z,12Z)/18:2(9Z,12Z))triacetate lactoneDiosmetin 7-O-beta-D-glucopyranosideAndrosteroneDihydrocurcuminS-AdenosylmethioninePiclozotanPC(34:4)PC(P-16:0/20:5(5Z,8Z,11Z,14Z,16E)-OH(18R))Deoxyguanosine1-Cyclohexyl-4-(1,2-diphenylethyl)piperazineOctadeca-2,9-dienoic acidL-ThymidineTasidotinCytidine monophosphate3,9-Dimethyl-6-(1-methylethyl)-1,4-dioxaspiro[4.5]decan-2-one(-)-AspidospermineAmrinone3-Palmitoyl-sn-glycerol(1beta,4E,8beta,10alpha)-1,10-Epoxy-4,11(13)-germacradien-12,8-olidePexacerfontAcolongifloriside KButyl nitriteL-Dihydroorotic acidbeta-(2-Methoxyphenoxy)-lactic acid3-MethylnonanoylcarnitineMalic acidPC(16:0/PGJ2)N-Docosahexaenoyl LysineLysoPE(16:0/0:0)Dimethyl carbonateAndrosterone sulfateGly-NorvalineMG(0:0/18:4(6Z,9Z,12Z,15Z)/0:0)N-Nitroso-pyrrolidineAloxistatin4-Vinylsyringol(2E,4E)-2,7-Dimethyl-2,4-octadienedioic acidDeterrolPC(34:2)Eplerenone9,10,13-Trihydroxystearic acidBenzonitrile, 3-amino-4-((2-((dimethylamino)methyl)phenyl)thio)-(E,E)-11,13-Octadecadien-9-ynoic acid(1Z,4Z)-1,5-bis(4-hydroxyphenyl)-1,4-pentadienePE(DiMe(9,3)/LTE4)2-Propenamide, 2-cyano-3-(4-hydroxy-3,5-bis(1-methylethyl)phenyl)-S-Ethyl dipropylthiocarbamateTriphenylethyleneTaurodeoxycholic acidPE(16:0/18:3(6Z,9Z,12Z))9,10-Epoxystearic acidProparacaineAlkaloid AQC2(-)-Huperzine AMiltironeL-2-Hydroxyglutaric acidPyrrolidineCyanoguanidinegamma-CrocetinBenzoyl chloride1-Phenyl-2-benzylaminopropaneCinnamyl cinnamate9-ArabinofuranosyladeninePC(18:2(10E,12Z)+=O(9)/2:0)3'-AMPVesnarinoneIsocolumbinNefopamDeoxycholic acid9-beta-d-Arabinofuranosylguanine3-hydroxytrideca-4,6-dienoic acidIsolinderenolidePC(20:5(6E,8Z,11Z,14Z,17Z)-OH(5)/2:0)PA(18:3(6Z,9Z,12Z)/18:2(9Z,12Z))9,10-DHOMEDurandro[9]-GingerolMethyl linolenateLysoPA(0:0/18:2(9Z,12Z))Butyric acidUndecanal propyleneglycol acetalPC(22:6(4Z,8Z,10Z,13Z,16Z,19Z)-OH(7)/2:0)Prolylproline2-Butyne-1,4-diol(R)-3',7-Dihydroxy-2',4'-dimethoxyisoflavanDifluoromethyl (2R)-2,5-diaminopentanoateCis-8,11,14,17-Eicosatetraenoic acid(+)-FargesinPolidocanolCoumatetralyl3beta-Hydroxypregn-5-en-20-one sulfateFlavin mononucleotidePS(14:0/15:0)N-EthylglycineHeptadecadienoic acidDG(13:0/20:3(8Z,11Z,14Z)-2OH(5,6)/0:0)Norecasantalic acidDG(16:0/18:1(9Z)/0:0)Thymidine 5'-triphosphateDihexyl phthalateDG(18:1n7/0:0/18:4n3)2-Ethyl-2-oxazolineSebiferic acidL-Pipecolic acid12-Ketodeoxycholic acidDG(18:1n9/0:0/18:4n3)5-Hydroxy-3',4',7,8-tetramethoxyflavone3-Methoxytyrosine1-(1-methylethenyl)-3-(1-methylethyl)-benzene(S)-3-(2-Methylphenoxy)propane-1,2-diol2-Naphthalenecarboxamide, 3-hydroxy-N-(2-methoxy-3-dibenzofuranyl)-RotigotinePS(18:4(6Z,9Z,12Z,15Z)/20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15))gamma-ButyrolactoneGlutathione12,13-DHOME7-oxononanoic acidPA(18:3(6Z,9Z,12Z)/18:3(9Z,12Z,15Z))Leucylleucine2-Ethyl-5,7-dimethyl-3-[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]imidazo[4,5-b]pyridine6-Methylmercaptopurinegamma-Glutamylphenylalanine3a,12b-Dihydroxy-5b-cholanoic acidtrans-10-Heptadecenoic acid3-hydroxynonanoyl carnitine1,9-PyrazoloanthroneEthyl butyrateDimetacrine(1(10)E,4beta,5alpha,8beta)-4,5-Epoxy-1(10),11(13)-germacradien-12,8-olide2-Pyridinemethanamine, N-((4-(1,4,8,11-tetraazacyclotetradec-1-ylmethyl)phenyl)methyl)-[3-[(2R,6S)-2,6-Dimethylpiperidin-1-yl]-4H-oxadiazol-3-ium-5-ylidene]azanideGlycerol 3-phosphatePC(P-18:1(11Z)/20:4(6E,8Z,11Z,14Z)+=O(5))LysoPE(0:0/14:0)MetamitronDodecyl benzenesulfonate1,2,3,4-TetrahydronaphthalenePC(14:0/LTE4)LysoPA(18:4(6Z,9Z,12Z,15Z)/0:0)Glycerophosphoglycerol3alpha,7alpha,12alpha-Trihydroxycholestanoic acidIndoleacetaldehyde11,12-DihydrolactaroviolinDiisopropylethylamine13-Docosenamide(2S,3R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholineLeukoaminochrome3-EpiaphidicolintetrahydropyridoindolePhthalic acid3-Furoic acidundeca-4,6-dienoic acidHydroxyprolyl-LeucineMetergoline2,4-Quinolinediol(1S,2S,6R,15S,16R)-5-(Cyclopropylmethyl)-16-(2-hydroxy-3,3-dimethylbutan-2-yl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-olLysoPS(16:0/0:0)4-HydroxyquinolineN-Acetyl-leucyl-leucyl-norleucinalDecadienyl-l-carnitineHydroxypropionic acidAndrostenedioneAmcinonidePA(18:2(10E,12Z)+=O(9)/18:2(9Z,11Z))Serine(5Z,8Z,11Z,14Z)-3-hydroxyicosa-5,8,11,14-tetraenoic acidCer(d16:1/22:6(5Z,7Z,10Z,13Z,16Z,19Z)-OH(4))Dibutyl decanedioatepyroglutamylisoleucineSambutoxinDL-ArginineN-Linoleoyl LeucineTridecanoic acidDibutylamine4-Hydroxybutyric acidAntimycin AIndantadolDihydroferulic acidTricycloekasantalJunicedralAdenosine monophosphateAllopurinol2,2-Dimethylpropanal 2,4-dinitrophenylhydrazoneUric acidDimepheptanolDL-NorvalineIntoplicine(6E)-8-Methylnon-6-enoylcarnitineCilostamideADP RiboseVal-glu-pro-ile-pro-tyrPC(16:0/18:2(9Z,12Z))3a,17a-Dihydroxy-5b-androstane2,2'-BioxiraneLysoPC(20:2(11Z,14Z)/0:0)2,4-Dimethyl-1-(1-methylethyl)-benzeneDodecanamide(S,E)-ZearalenoneStearidonic acid1,1,1-Trifluoroheptadecan-2-one(+/-)-trans- and cis-2-Hexenal propylene glycol acetalSatratoxin GOrientin 7,3'-dimethyl etherErythritolEcgonineEugenyl isovalerate(2R,3S)-3-Hydroxy-1,1-dimethylpyrrolidin-1-ium-2-carboxylate9-HOTEOctadeca-9,11-dienoic acidVolasertib(2R,5S)-2-(6-Aminopurin-9-yl)-5-(methylsulfanylmethyl)oxolane-3,4-diolL-IditolDehydroepiandrosterone sulfateAcetaminophen2,5-Dimethylthiophene5'-Hydroxypiroxicam5,7-Dihydroxy-3',4'-dimethoxy-8-(3-hydroxy-3-methylbutyl)-isoflavone 7-glucosideTrehaloseSuccinic anhydridePseudolaric acid-BUridine diphosphategalactoseGuanine5-hydroxytetradecanedioic acidDL-GlutamateTropate(Z,Z,Z)-1,8,11,14-HeptadecatetraeneLucidenic acid D12,4,6-Tris(dimethylaminomethyl)phenolMahanimbinolCholestane-3,7,12,24,25-pentolIsoxabenPimavanserinCitric acidGlycylleucine2,4-Dihydroxy-nitrophenol9,12,15-Octadecatrienoic acid 1-[(phosphonoxy)methyl]-1,2-ethanediyl esterCDP-DG(i-12:0/18:1(12Z)-2OH(9,10))1-[(1R,2R,3S,4S)-3-Hydroxy-4,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl]-3-(4-methylphenyl)sulfonylureaDoxapramgamma-MangostinPG(i-17:0/20:4(5Z,8Z,11Z,13E)+=O(15))Adelmidrol(5Z,9Z,12Z)-octadeca-5,9,12-trienoic acidCoroninb-DihydrotetrabenazineGlycocholic acidZingerone2-Acetyl-3,5,5,6,8,8-hexamethyl-5,6,7,8- tetrahydronaphthaleneLithocholyltaurine(-)-PyrifolidineGanciclovirVerimol HPG(a-17:0/20:3(8Z,11Z,14Z)-O(5,6))DieporeticaninStachyoseVerimol B(E)-2-Methylglutaconic acidPE(14:0/15:0)Methyl 2-thiofuroateRibalinium1,1-DichloroethanePS(18:2(9Z,12Z)/LTE4)DG(18:3n3/0:0/18:4n3)PC(15:0/20:5(5Z,8Z,11Z,14Z,17Z))N1,N5,N10-Tris-trans-p-coumaroylspermineGlutathionate(1-)1-H-Inden-1-one,2,3-dihydro-3,3,5,6-tetramethylGarcinone Dtrans-zeatin ribosideMyrigalone ABazedoxifenePC(18:3(10,12,15)-OH(9)/2:0)PE(18:2(9Z,12Z)/18:3(6Z,9Z,12Z))androst-5-ene-3,17-dioneAzimexon(9Z,12Z,14E)-16-Hydroxy-9,12,14-octadecatrienoic acidAllopurinol ribosideDehydrochorismic acid(11R,12S,13S)-Epoxy-hydroxyoctadeca-cis-9-cis-15-dien-1-oic acidPC(P-16:0/18:2(10E,12Z)+=O(9))Formycin A4-CarboxypyrazoleTaurolithocholic acid 3-sulfatePA(10:0/PGJ2)Rubusoside[4-[(2R)-7-(2,2-Dimethylpropanoyloxy)-4-methyl-2-[4-(2-piperidin-1-ylethoxy)phenyl]-2H-chromen-3-yl]phenyl] 2,2-dimethylpropanoateGosogliptinMethyl dihydroepijasmonateCytidine 3'-monophosphate(alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform A (protein)KirenolTasosartanPS(14:1(9Z)/16:1(9Z))OxetoroneMammea B/AD cyclo D(10Z)-12-hydroxyhexadec-10-enoic acidBaikiainSarcosine22-Hydroxydocosanoic acidLysoPE(24:0/0:0)SorbitolPG(22:6(4Z,8Z,10Z,13Z,16Z,19Z)-OH(7)/i-15:0)Pregn-4-ene-3,20-dione, 11,17,18,21-tetrahydroxy-, (11beta)-Fluanisone(¡À)-Tryptophan4-Chloro-2-methylphenolCer(d17:1/LTE4)Trifluoroacetic acidDigimed12(13)Ep-9-KODE2,6-Dimethyl-naphtalene4-tert-Butylphenyl salicylatePG(i-19:0/5-iso PGF2VI)ArgenteaneNaftopidilGanoderic acid JGanoderic acid HCetirizineAcetic anhydrideEtofenproxFedratinib(11E)-tridec-11-enoic acidTrinexapacCyclohexanecarboxamide, n-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-n-2-pyridinyl-Linaprazantrans-Aconitic acidLeukotriene D4Ethyl alpha-linolenateSecoisolariciresinol 9,9'-diglucosideLysoPC(20:5(5Z,8Z,11Z,14Z,17Z)/0:0)Pandamarilactone 321,26-Hexacosanediol diferulatedTDP-D-glucose1-HeptadecanoylglycerophosphoethanolamineLeukotriene C4SuloctidilL-TryptophanAdouetine XN-Linoleoyl GlutamineCropropamideOctadeca-2,4-dienedioic acid2,3-DinitrophenolPhenylalaninePiperonyl butoxide4-Guanidinobutanoic acidProlylhydroxyprolineEnokipodin ALeukotriene B4Decenoylcarnitine(¡À)-erythro-IsoleucinePC(2:0/PGF2alpha)UracilCorynanthineEmedastineAcetylhomoserine2-Chlorohexadecanoic Acidalpha-(4-Fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol3-Methylbenzaldehydealpha-Caryophyllene alcohol acetateProtohypericinTyr-Gly-Gly-Trp-LeuInosinic acidMocetinostat9-Oxo-nonanoic acidN-NitrosoanatabineCholesterol sulfateArmillasinOctyl gallate(9S,10E,12S,13S)-9,12,13-Trihydroxy-10-octadecenoic acidPseudoisoeugenol 2-methylbutanoate7,8-DihydroxyflavoneSimazineTaxifolin 3-arabinosideMargaroylglycineLysoPC(18:1/0:0)Oxalic acidhydroxyoctadecadienoic acid5-AminoimidazoleDG(TXB2/i-14:0/0:0)Kobusone1-Phenyl-1,3-dodecanedione2-Oxovaleric acid1,3,5-HexatrieneFlavidulol CDiftaloneFuberidazolePC(P-18:0/15:0)ButylbenzeneSM(d18:1/PGJ2)5,9:6,9-Diepoxy-3-megastigmene3,4',5-BiphenyltriolDocosatetraenylethanolamide2-PropanoylthiazoleLysoPA(18:3(9Z,12Z,15Z)/0:0)Indinavirp-Octopamine(9Z)-pentadec-9-enoic acidDifenoconazole3,3',4,4'-Tetrahydroxy-5,5'-diisopropyl-2,2'-dimethylbiphenylPE(16:0/18:2(9Z,12Z))(-)-NopolDimethoxycarbene2-HydroxyphenethylamineMethyl 1-pentyl-1H-indole-3-carboxylic acidHeptadecanoic acid5-Methyl-2,5-di-1-pyrrolidinyl-2-cyclopenten-1-one(R)-Methylphosphonofluoridic acid 1,2,2-trimethylpropyl esterGlutamineLysoPC(22:2(13Z,16Z)/0:0)Corchorifatty acid FTebufelonePalmitic acidbeta-Glycerophosphoric acid5-Pentyltetrahydro-2-oxo-3-furancarboxylic acidLysoPE(18:1(9Z)/0:0)3-Amino-2-oxazolidonepyroglutamyltryptophanD-Glycero-D-galacto-heptitolPC(2:0/22:6(5Z,7Z,10Z,13Z,16Z,19Z)-OH(4))PerezoneBrompheniraminePergolideEupolauridine6-HydroxyemedastineTrombodipineNimbolideFormononetinAmikacinPlatelet-activating factor2-Hydroxy-4-methylbenzaldehydeTrilostaneN-NitrosodimethylaminePS(20:5(5Z,8Z,11Z,14Z,17Z)/22:6(5Z,8E,10Z,13Z,15E,19Z)-2OH(7S, 17S))EthylphosphateDronedarone1,2,3,4-Tetrahydro-1-phenyl-4-(1-phenylethyl)naphthaleneProstacyclin (not favourable)Perphenazine decanoateIndoleacetic acid1,3-DiphenylpropaneD-Aspartic acid(¡À)-(E)-13-Hydroxy-10-oxo-11-octadecenoic acidResolvin E2N-LactoylphenylalanineErythroseEleclazineGlabrolideXanthine6-Hydroxydecanoylcarnitine(8R,9R,10R,13S,14S)-10,13-Dimethyl-5,6,7,8,9,11,12,14,15,16-decahydro-4H-cyclopenta[a]phenanthrene-3,17-dione5-hydroxytrideca-7,9-dienoic acidDimethylnitramineUridine diphosphate glucuronic acidParenabol3-(4-Hydroxy-3-methoxyphenyl)-2-methyllactic acidPC(P-16:0/18:1(12Z)-O(9S,10R))LysoPI(18:1(9Z)/0:0)CarbohydrazideGlutamylhistidine(2R)-2-Hydroxy-3-[(hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl)oxy]propyl (9Z,12Z)-octadeca-9,12-dienoateIndolineMaleic acidGluconic acid2-Aminopurine7-Hydroxymethyl-12-methylbenz[a]anthraceneUndecanedioic acidS-Adenosylhomocysteine2,4-DihydroxybenzophenonePE(18:2(9Z,12Z)/20:3(5Z,8Z,11Z))SolasodineDiketeneDimethyltriazenoimidazole carboxamide9-OctadecenamidePhthalic anhydrideNordihydrocapsaicinIbrutinibTrehalose 6-phosphatePinokalant(3Z,9Z)-hexadeca-3,9-dienoic acid(2S)-2-Amino-3-[4-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]oxy-3-chlorophenyl]propanoic acid7-Hydroxy-3',4',5,6-tetramethoxyflavonePE(16:0/18:1(9Z))Perillic acidPiperidine3,4-Dihydro-2H-pyrimido[1,2-c][1,3]benzothiazin-6-imineLysoPG(18:1(9Z)/0:0)D-OrnithineSedoheptulose 7-phosphateAcetamide, 2-((2-hydroxyethyl)thio)-N-(3-(3-(1-piperidinylmethyl)phenoxy)propyl)-Albendazole2-Cyanoacetamide2-O-MethylinosineVanillinEnzastaurin1-HydroxybenzotriazoleOxyphencyclimine5,4'-Dihydroxy-3,3'-dimethoxy-6:7-methylenedioxyflavone(4E,7E)-3-hydroxydeca-4,7-dienoic acid2'-O-MethyluridineRibociclibRiboflavinQuingestanol(+)-AspidospermidineLimoninLotrafibanDeoxyinosineSM(d18:0/PGJ2)QuinolineHeptanoic acidCuminyl alcoholTriticonazoleO-MethylsomniferineN-(alpha-Linolenoyl)tyrosineHarman5-O-Methylembelin(E)-2-Cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)acrylamideMebhydrolinKukoamine CAnileridineKukoamine BN2-Methyl-L-argininePE(22:5(4Z,7Z,10Z,13Z,16Z)/20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15))Octadecanedioic acid2H-Benzo(a)quinolizin-2-ol, 2-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-N-(p-Hydroxyphenethyl)actinidineAlpha-Linolenoyl ethanolamideHexaminolevulinateNordihydrocapsiate5-Hydroxyindoleacetic acidPA(18:2(9Z,11Z)/18:1(12Z)-O(9S,10R))Ile-Val-Val1,2,4-Tris(methylene)cyclohexane1-(1-Naphthyl)-2-thioureaBudipineMethyl glycinate(¡À)-3-Hydroxynonanoic acidGuanosine monophosphateGlutaric acidTetrahydrocannabinolLinopirdineAdenylsuccinic acidUDP-N-acetyl-alpha-D-galactosamineDL-Acetylcarnitine2,2,2-Trifluoro-N-methyl-N-(trifluoroacetyl)acetamide1-PiperidinecarboxaldehydeTelenzepineMonoethyl carbonateLysoPC(18:0/0:0)CDP-DG(20:4(5Z,8Z,11Z,14Z)-OH(20)/i-15:0)Prostaglandin F-main urinary metabolite(10Z)-7-hydroxyhexadec-10-enoic acid(S)-RutaretinPC(32:2)PA(18:3(6Z,9Z,12Z)/20:3(8Z,11Z,14Z))Cysteinyl-PhenylalanineZopiclone N-oxide(5Z,8Z,10E,12E,14Z)-icosa-5,8,10,12,14-pentaenoic acid3,5,5-Trimethyl-1,2-cyclohexanedioneIsomasticadienonalic acidPraziquantel1,5-HexadieneCenicrivirocN-Acetyl-L-methionineTrimebutine1-PalmitoylphosphatidylcholinePipequaline1-Methyl-4-isobutylbenzeneADPN-Hexadecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate1,3,7-Trimethyluric acidGlyceric acidLucerastatLysoPE(14:0/0:0)AlanylphenylalanineCyclic AMP[(3S,8R,9S,10S,13S,14S)-10,13-Dimethyl-17-oxo-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-3-yl] hydrogen sulfate1-Methoxyphaseollidin2-Aminoisobutyric acidAprindineDG(a-13:0/22:6(4Z,8Z,10Z,13Z,16Z,19Z)-OH(7)/0:0)PyrophosphateUridineCyproconazoleComfreyEicosanedioic acidBifonazole3-hydroxydecanoyl carnitine2,3-Epoxymenaquinone6beta-HydroxyfluoxymesteroneD-ThreitolFentanylProlineTrimetaphosphoric acidPS(18:1(9Z)/20:4(5Z,8Z,11Z,14Z))1,6-Bis(cyclohexyloximinocarbonyl)hexaneEthyl apovincaminateDinorpropoxyphene5-methylheptadecanoic acid1,2-DichloroethaneGlycoursodeoxycholic acidN-Tetradecyl-N,N-dimethyl-3-ammonio-1-propanesulfonateN-AcetyltryptophanNorecasantalal(8Z)-10-hydroxyhexadec-8-enoic acidSalsoline-1-carboxylatePaeonimetabolin I15,16-DiHODENADFumaric acidL-TyrosineTyromycic acid3-Phenyl benzaldehyde1-NaphthylamineDimoracinLevonorgestrel butyrate(8S,9R,11S,13S,14S,17S)-13-Methyl-11-[4-[5-(4,4,5,5,5-pentafluoropentylsulfonyl)pentoxy]phenyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diolSucrose(11E,13Z)-10-hydroxyoctadeca-11,13-dienoic acid2'-Deoxyguanosine 5'-monophosphate2-Methyl-1,3-cyclohexadieneShinflavanonegamma-Glutamyltyrosine4-methylheptadecanoic acidTriclofos1,2,3-TrimethoxybenzeneAvocadene 1-acetateLevoinositol(10Z,14E,16E)-10,14,16-Octadecatrien-12-ynoic acidPA(18:1(9Z)-O(12,13)/20:3(5Z,8Z,11Z))Methoxyacetic acidAdenosine, 8-(butylamino)-N-cyclopentyl-CephaelineSorbitan laurate2-Isopropylmalic acid(S)-2-Azetidinecarboxylic acid3-[[(2S)-2,4-Dihydroxy-3,3-dimethylbutanoyl]amino]propanoic acidPropionylcarnitineLysoPC(20:3/0:0)Dioctyl phthalateAspartylphenylalanine3-methyltetradecanoic acidBunitrololDihydrosinapic acidPerindopril6-Methylgingediol2-(Diethylamino)ethyl methacrylate1,6,7-TrimethylnaphthaleneSuberic acid(-)-Chimonanthine5-O-MethylgenisteinLicoagrodinPaeonol9-HydroxyfluoreneCaffeoylferuloylspermidine5'-Methylthioadenosinealpha-D-Glucose 1,6-bisphosphateAcetophenone(8R,9R,10R,13S,14S)-10,13-Dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7,17-triolCreatinineStachyflinAllopregnanolone sulfateTiloronePentolameTetramethylscutellareinDi-N-propylamineAcoramone11-trans-Leukotriene C44-DeoxycohumuloneMoexiprilDodeca-3,5,7-trienoylcarnitine3-Hydroxyphenyl-valeric acid4,8,12,15-Octadecatetraenoic acidLysoPC(20:1(11Z)/0:0)Erinacine BErinacine CDG(15:0/20:4(7E,9E,11Z,13E)-3OH(5S,6R,15S)/0:0)PC(18:4(6Z,9Z,12Z,15Z)/22:6(4Z,7Z,11E,13Z,15E,19Z)-2OH(10S,17))Palmitic amideLexibulin5-Hexyltetrahydro-2-furanoctanoic acidBilirubinSterebin AUridine diphosphate-N-acetylgalactosamine8-Hydroxydecanoylcarnitine(9S,10E,12Z,15Z)-9-Hydroxy-10,12,15-octadecatrienoic acidCDP-ethanolamine(8S,9S,10S,13S,14S,17R)-17-Hydroxy-17-(2-hydroxyacetyl)-1,10,13-trimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dioneisopentenyl adenosineDIMBOA trihexose3-Hydroxytetradeca-5,8,11-trienoylcarnitine2-(2-Furanyl)-3-piperidinolXanthenone-4-acetic acid7-hydroxytetradecanedioic acidTryptopholTamoxifen-N-oxidecis-3-Hexenyl isobutyratetrans-2-Hexenedioic acidDimethylbenzimidazoleOsimertinibDodecanoic acidUridine 5'-diphosphateAdenosine diphosphate-D-riboseSphinganine2,4-Pyrimidinediamine, 5-(5-(1-piperazinylmethyl)-1,3,4-oxadiazol-2-yl)-N4-propyl-N2-(2-(4-pyridinyl)ethyl)-14-DeoxyandrographolideAlvimopanDeptropine2,4-Dimethylquinolinem-Ethyl_tolueneMethyprylonN-Acetyl-9-aminominocycline, (4R)-3-Hydroxy-2-octanone(2'E,4'Z,7'Z,8E)-Colnelenic acidTyphaneosideOxybutyninSulfateProgesteronePC(14:1(9Z)/16:1(9Z))KetanserinIsonicotinic acidD-FructoseEmbelin(2S,3R,4S,5S,6R)-2-[2,4-Dihydroxy-6-[(E)-2-(4-hydroxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triolPrunetin3-hydroxytridecanoyl carnitineGlycyl-Tryptophan2-beta-hydroxymedroxyprogesterone2-Amino-5-benzoylbenzimidazoleTrilobinonebeta-noroxycodolGuanosine diphosphate4-Hydroxy-2-butenoic acid gamma-lactoneDG(10:0/0:0/8:0)1,3,9-Trimethyluric acidPhenylalanylleucineMethioninealpha-Ketoisovaleric acid3-EthylthiopheneLinalyl caprylateBenzamidinePerlapineSalicylanilide3-Methyl-1-butylamineEremopetasitenin D15b-Cholestane-3a,7a,12a,24,25-pentolOctanal propyleneglycol acetal2,3-Dihydroxy-9,10,11-trimethoxy-5,8,13,13a-tetrahydroxy-6H-dibenzo(a,g)chinolysin9,12-Octadecadiynoic acid2-Methyl-6-ethylpyridine4-Amino-1,2,4-triazoleDodecatrienoic acid(8R,9S,10R,13S,14S,17R)-13-Ethyl-17-ethynyl-3-nitroso-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-olPG(20:4(6E,8Z,11Z,14Z)+=O(5)/i-17:0)Meta-TyrosinePC(P-18:0/18:1(12Z)-O(9S,10R))(3beta,5alpha,6alpha,7alpha,22E,24R)-5,6-Epoxyergosta-8,14,22-triene-3,7-diolDiaminopimelic acid3-methylpentadecanoic acidtert-Butyl isocyanideN-Lauroyl Glutamine3-hydroxytrideca-5,8-dienoic acidMelizame(8S,9S,10R,13R,14S,17R)-5,6-Dihydroperoxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,3,4,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-olPG(PGE2/a-17:0)Octadec-9-enoic AcidIndole-3-propionic acidD-Valine20-Hydroxy-6Z,15Z-eicosadienoic acid(Tetrahydropyran-4-yl)-[2-phenyl-5-(1,1-dioxo-thiomorpholin-4-yl)methyl-1H-indol-7-yl]amineHeterophyllinalpha-ZearalenolPC(36:3)PIP(20:2(11Z,14Z)/20:3(8Z,11Z,14Z)-O(5,6))PhytosphingosineTetradecyl nicotinateRhizoxinOxyhyponitritePIP(18:2(9Z,12Z)/6 keto-PGF1alpha)N-Linoleoyl Glycine(2S)-3-Hydroxy-1-[(2S)-pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acidN6-(delta2-isopentenyl)-adenosine 5'-monophosphate5,9:6,9-Diepoxy-4-megastigmeneCedranoxideSM(d18:2(4E,14Z)/18:1(12Z)-2OH(9,10))(5E,9E)-3-hydroxytrideca-5,9-dienoic acidGlyceollin IIIValylleucineIsobutambenFumitremorgin CHydroxyfasudilalpha-Hydroxyisobutyric acid(3E,5E)-1,3,5-octatrieneDiheptyl phthalateCeanothine CSuccinic acidN-Arachidonoyl GlycinePiromidic acidL-Argininegamma-Linolenic acidalpha-Linolenic acidBenzothiazoleLysoPC(0:0/18:0)PivagabinePhenylethylamine(R)-3,4-Dihydro-8-hydroxy-3-tridecyl-1H-2-benzopyran-1-oneSantaloneLysoPG(18:2(9Z,12Z)/0:0)4-Chloro-3-methylphenol(10E,13E)-nonadeca-10,13-dienoic acid10,11-dihydro-leukotriene B4octadecenedioateArmillatinPronetalolMG(LTE4/0:0/0:0)4-hydroxytrideca-7,10-dienoic acidNebivololPA(18:3(6Z,9Z,12Z)/16:0)(-)-FolicanthineFADNaloxoneAdavosertibD-ProlineLinalool oxide D 3-[apiosyl-(1->6)-glucoside]1-MethoxyphenanthreneInosinePentadecanoylglycine2-hydroxy-3-(sulfooxy)benzoic acidLumichromeButyl-(2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo(2,3-d)pyrimidin-4-yl)ethylamineD-PhenylalanineN-Stearoyl Cysteine2-PyrrolidinoneRoxatidine acetateEmopamilMethyl palmoxirate3,4-Dimethyl-5-pentyl-2-furanheptanoic acidAplotaxene3,4-Dimethylbenzoic acidpiperazine-2,3-dione11,12-Epoxyeicosatrienoic acid(5E)-5-[(3Ar,4S,5S,6aR)-5-hydroxy-4-[(E,3R)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoic acid4-Cyano-N-(3-(cyclopropyl(5,6,7,8,9,10-hexahydro-4-hydroxy-2-oxo-2H-cycloocta(b)pyran-3-yl)methyl)phenyl)benzenesulfonamide((4-(4-Amidinophenoxy)butanoyl)aspartyl)valineMoperoneFingolimod phosphate ester, S-CaffeineBopindololDesmethylmianserinFlibanserinN-Carboxymethyllysine6-(Diethylamino)-N-[2-[(1R)-3-methyl-7-oxo-5,10-diazatetracyclo[7.4.0.01,12.02,6]trideca-2(6),3,8-triene-10-carbonyl]-1H-indol-5-yl]-1-benzofuran-2-carboxamideGlyceryl monolinoleateN-Myristoyl AlanineDebrisoquineSoyasaponin IHeptaethylene glycolD-XylitolSarpogrelateN-Myristoyl SerineSebacic acidPC(18:3(9Z,12Z,15Z)/18:3(9Z,12Z,15Z))D-ThreonineSphinganine 1-phosphateMethyl dihydrojasmonate8-Methylquinoline12(13)-epoxy-6Z,9Z-octadecadienoic acidPhenylalanyl-prolyl-arginine nitrileTetrofosminDiglycolic acidDorsomorphinNicotyrineMangostinonePC(20:3(6,8,11)-OH(5)/2:0)GuaiacinPC(2:0/18:2(10E,12Z)+=O(9))Isomucronulatol5,7-Dihydroxyflavone9Z,12E-Octadecadienoic acidDodecanedioic acidMethoxy arachidonyl fluorophosphonateElenaic acid(3E,5Z)-1,3,5-Heptatriene3-Hydroxyhexadecanoic acidN-Palmitoyl Asparaginep-Benzoquinone imineGingerolS-Acetyldihydrolipoamide-EAllixinFluoresceinIndaneUvaolN-(14-Methylhexadecanoyl)pyrrolidine(6E)-undec-6-enoic acidMycochromoneOctylguanidineL-Threo-3-Phenylserinexi-2,3-Dihydro-2-oxo-1H-indole-3-acetic acidPhosphodimethylethanolamine6-KetoestriolPE(14:0/18:2(9Z,12Z))Thymidine5,9-Epidioxy-3-hydroxyergost-7-en-6-one3,4-Dihydroxyphenylvaleric acidDiphenylamineCDP-DG(i-12:0/18:2(10E,12Z)+=O(9))2-Methyl-3-oxopropanoic acidPantetheineD-AlanineIndole-3-acetamideMethylmalonic acid6-oxononanoic acidPA(20:4(8Z,11Z,14Z,17Z)/18:1(9Z))Phytocassane B3-(4-Hydroxy-3-methoxyphenyl)-1,2-propanediolDHAP(18:0)Palmitoyl chlorideN-Acetylsulfamethazine3-Phosphoglyceric acidDocebenoneAnthecotulide(2R,3R)-2-Aminooctadecane-1,3-diol3,7,11,15,23-Pentaoxolanost-8-en-26-oic aciddihydroxyferuloyl-sinapoyl spermidineMiltefosine2-PentylthiopheneN,N'-Dibenzhydrylethane-1,2-diamineChaetoglobosin NCDP-DG(i-13:0/18:1(9Z)-O(12,13))MitragynineLysoPE(22:1(13Z)/0:0)Ganoderic acid C1Soyasaponin IIIalpha-Naphthoflavone5-Hydroxy-4-methoxy-5-(1-oxo-9,12,15-hexadecatrienyl)-2(5H)-furanoneCer(d16:1/LTE4)Azelaic acidAcutilobin(E)-Piperolein ATrifluoromethyl iodide(9Z)-nonadec-9-enoic acid3-Isobutyl-1-methylxanthine[(2R,5R)-5-(2-Amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphateDiethyltoluamidePC(18:4(6Z,9Z,12Z,15Z)/20:4(8Z,11Z,14Z,17Z)-2OH(5S,6R))Deoxyadenosine monophosphateVindesine(-)-Epigallocatechin 3,4'-di-gallate12-Keto-tetrahydro-leukotriene B4NorvalinePiperidine, 1-(4-(1-methyl-1-(4-methylcyclohexyl)ethoxy)phenyl)-, cis-Foeniculoside VIIAsiaticosidefalseMechanistic profiling of Bifemetstrobin against the tea anthracnose pathogen and candidate evaluation of an amine oxidase targetTea anthracnose caused by Glomerella cingulata threatens yield and quality, while resistance to legacy fungicides highlights the need for new modes of action. We characterized the antifungal activity and mechanism of bifemetstrobin against G. cingulata by combining efficacy assays with cell biology and integrated multi omics. Bifemetstrobin inhibited mycelial growth (EC50 = 5.04 μg/mL) and spore germination and provided up to approximately 80% curative suppression on detached tea leaves. Microscopy revealed dose dependent hyphal and conidial deformation and mitochondrial injury. Consistently, bifemetstrobin collapsed mitochondrial membrane potential (MMP), reduced intracellular ATP, and increased membrane leakage with depletion of reducing sugars and soluble proteins. Transcriptome, data-independent acquisition (DIA) proteomics and metabolome data converged on reprogramming of carbohydrate and amino acid metabolism, membrane processes, and redox homeostasis, with DNA replication signatures emerging at the higher dose. Cross-layer mapping prioritized an amine oxidase (AO) as a hub. Bifemetstrobin bound AO with micromolar affinity (microscale thermophoresis/isothermal titration calorimetry), supported by docking and molecular dynamics, and outperformed azoxystrobin in binding. Pairing bifemetstrobin with pyrrolnitrin yielded strong in vitro synergy and improved leaf protection. Across additional phytopathogens, bifemetstrobin retained activity in vitro (EC50 range 1.19–27.38 μg/mL), outperforming azoxystrobin on the tea anthracnose strain. These findings nominate AO as a high confidence candidate supported by binding assays and link target engagement to mitochondrial failure and carbon-nitrogen reprogramming, supporting bifemetstrobin (alone or in rational mixtures) as a promising candidate for tea anthracnose management.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