MetaboLights

application/xml

ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14093/m_MTBLS14093_LC-MS_negative__metabolite_profiling_v2_maf.tsvftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14093/m_MTBLS14093_LC-MS_positive__metabolite_profiling_v2_maf.tsvftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14093/a_MTBLS14093_LC-MS_negative__metabolite_profiling.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14093/s_MTBLS14093.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14093/a_MTBLS14093_LC-MS_positive__metabolite_profiling.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14093/i_Investigation.txtprimaryOK200ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14093The raw data of the mass spectrometer was converted into mzML format by ProteoWizard, and peak extraction, alignment, and retention time correction were performed using XCMS program. Filter the peaks with a missing rate>50% in each group of samples, fill in the blank values with KNN, and use SVR method to correct the peak area. The peaks after calibration and screening were identified for metabolites by searching the laboratory's self built database, integrating public databases, prediction databases, and metDNA methods. Finally, extract substances with a comprehensive identification score of 0.5 or above and a QC sample CV value less than 0.3, and then merge the positive and negative modes (retaining the substance with the highest qualitative level and the smallest CV value) to obtain the final data.MetaboLightsPublicLiquid Chromatography MS - positiveLiquid Chromatography MS - negativeAll samples were for two LC/MS methods. One aliquot was analyzed using positive ion conditions and was eluted from T3 column (Waters ACQUITY Premier HSS T3 Column 1.8 µm, 2.1 mm all_fetch_status all_status eb_eye_copy_status eb_eye_entry_counts eb_eye_fetch_status eb_eye_metabolights_complete.xml eb_eye_metabolights_compounds.copy eb_eye_metabolights_compounds.xml eb_eye_metabolights_studies.copy e_fetch_status europe_PMC_metabolights_studies.copy europe_PMC_metabolights_studies.xml head.xml studies.copy study.xml tail.xml thomsonreuters_metabolights_studies.copy thomsonreuters_metabolights_studies.xml 100 mm) using 0.1 % formic acid in water as solvent A and 0.1 % formic acid in acetonitrile as solvent B in the following gradient: 5 to 20 % in 2 min, increased to 60 % in the following 3 mins, increased to 99 % in 1 min and held for 1.5 min, then come back to 5 % mobile phase B witnin 0.1 min, held for 2.4 min. The analytical conditions were as follows, column temperature, 40 °C; flow rate, 0.4 mL/min; injection volume, 4 μL; Another aliquot was using negative ion conditions and was the same as the elution gradient of positive mode. Clostridium butyricum ameliorates meat quality in coccidiosis-affected sheep by rescuing thiamine diphosphate mediated glucose metabolism.Sodium Butyrate Ameliorates Meat Tenderness in Coccidia-infected Sheep via Reprogramming the Gut–Muscle Metabolic Axis.Dietary Clostridium butyricum alleviates coccidiosis-induced metabolic stress and preserves meat quality through modulation of the gut microbiota–butyrate–muscle axis in sheep.Henan Agricultural UniversityManyu Liulongissimus dorsi massmass spectrometry assayThe sample stored at -80 °C refrigerator was thawed on ice. The sample was grinded with liquid nitrogen. A 400 μL solution (Methanol : Water = 7:3, V/V) containing internal standard was added into 20 mg grinded sample, and shaked at 1500 rpm for 5 min. After placing on ice for 15 min. the sample was centrifuged at 12000 rpm for 10 min (4 °C). A 300 μL of supernatant was collected and placed in -20 °C for 30 min. The sample was then centrifuged at 12000 rpm for 3 min (4 °C). A 200 μL aliquots of supernatant were transferred for LC-MS analysis.Ovis arieshttps://www.ebi.ac.uk/metabolights/MTBLS14093Liu Manyu. Henan Agriculture university in Zhengzhou. 18438615175@163.com.Jian Fuchun. Henan Agriculture university in Zhengzhou. jfchun2008@163.com.The raw data of the mass spectrometer was converted into mzML format by ProteoWizard, and peak extraction, alignment, and retention time correction were performed using XCMS program. Filter the peaks with a missing rate>50% in each group of samples, fill in the blank values with KNN, and use SVR method to correct the peak area. The peaks after calibration and screening were identified for metabolites by searching the laboratory's self built database, integrating public databases, prediction databases, and metDNA methods. Finally, extract substances with a comprehensive identification score of 0.5 or above and a QC sample CV value less than 0.3, and then merge the positive and negative modes (retaining the substance with the highest qualitative level and the smallest CV value) to obtain the final data.Eimeria spp. infection18438615175@163.comOn days 0, 21, and 40, 5 mL jugular blood samples were collected and prefed into procoagulant tubes. The samples were gently inverted and mixed and subsequently allowed to stand before centrifugation at 3000×g for 10 minutes. The serum was then collected and preserved at -80 °C for further analysis. After 40 days, the lambs were fasted for 12 h and euthanized via jugular exsanguination, and the abdominal cavity was dissected to remove all internal organs. Muscle samples (2 g) from the longissimus dorsi (LT) muscle (between the 10th and 13th ribs on the left side of the corpse) were stored in EP tubes on dry ice for transcriptome and nontarget metabolome sequencing (Mavis Biotechnology). An extra 5 g of muscle sample was procured in liquid nitrogen for subsequent laboratory analysis. Approximately 500 g of muscle sample was stored at 4 °C for the evaluation of meat quality.Metabolomicsmeat qualityProbioticsParasitic diseaseglucose metabolismmeat qualityProbioticsParasitic diseaseglucose metabolismAll the methods alternated between full scan MS and data dependent MSn scans using dynamic exclusion. MS analyses were carried out using electrospray ionization in the positive ion mode and negative ion mode using full scan analysis over m/z 75-1000 at 35000 resolution. Additional MS settings are: ion spray voltage, 3.5 KV or 3.2 KV in positive or negative modes, respevtively; Sheath gas (Arb), 30; Aux gas, 5; Ion transfer tube temperature, 320 °C; Vaporizer temperature, 300 °C; Collision energy, 30,40,50 V; Signal Intensity Threshold, 1*e6 cps; Top N vs Top speed, 10; Exclusion duration, 3s.Saikosaponin ADL-2-Aminooctanoic acidScutigeralCycloate8-Aminooctanoic acidAltretaminealpha,alpha'-Trehalose 6-mycolateCyanidin 3-sambubioside 5-glucosideUridine 5'-triphosphateLPC(18:1/0:0)Xanthotoxol geranyl ethertrans-SulindacGlu-Lys-Leu-Thr-His(2S)-N-tert-butyl-3-[4-(2-methoxyphenyl)piperazin-1-yl]-2-phenylpropanamideLys-Ser-Leu-Ala-Met(3S,4S,5S,6R)-2-[(3R,4S,5S,6R)-4,5-dihydroxy-2-[[(3S,5R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triolGlycyl-tyrosyl-lysineFuraltadone HClbafilomycin A13-(1,3,4-Oxadiazol-2-yl)anilinecyanidin 3-O-beta-D-(caffeoyl)-sambubiosideDesipramineIle-Val-Leu-GluCauloside CHis-Phe-AsnMevalonic acidArginylprolineSecobarbitalSimplexinEliglustatPC(O-16:0/20:5(5Z,8Z,11Z,14Z,17Z))Epoxyfarnesyl-5,7-dihydroxy-4,6-dimethylphthalideSilodosinN-PhenethylacetamideCMP-N,N-diacetyllegionaminic acidCarnitine ph-C1Cinchonine2,2',3-Trihydroxy-3'-methoxy-5,5'-dicarboxybiphenyl1-((S)-2-aminopropyl)-1H-indazol-6-olRed chlorophyll cataboliteCaffeic acidSudachiin CMethylephedrineC-12 NBD-dihydro-CeramideAdenosine-5'-diphosphatePyroglutamylleucyllysineCinnamic Acid17beta-Acetamidoandrost-4-en-3-oneMet-Val-His-Leu-Thr5-Fluoropyrimidine-2-carbonitrilebeta-FructofuranosidasePantothenic aciddTDP-4-dehydro-6-deoxy-alpha-D-gulosePC(20:5(5Z,8Z,11Z,14Z,17Z)/20:5(5Z,8Z,11Z,14Z,17Z))Ursodeoxycholic acid 3-sulfateN-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(5-fluoropentan-1-yl)-1H-indole-3-carboxamideThr-Phe-Glu-Glu-AspCarnitine C8-OHBW-245Ccis-1,2-Dihydro-3-ethylcatecholCaldariellaquinoneNomifensine maleateD-erythro-MAPP2-Methyl-4-pentenoic acid3-NitrophenylhydrazineVal-Ile-Asp-Lys2,3-Butanediol glucosideResveratrol 4'-O-beta-D-(2''-O-galloyl)-glucopyranoside1-pentadecanoyl-2-(13Z,16Z-docosadienoyl)-glycero-3-phosphocholineGDP-L-gulose1,2-Dimyristoyl-sn-glycero-3-phosphocholine4beta-HydroxycholesterolSer-Arg-Ala-LysCreatine monohydrate(Z)-2-(sulooxymethyl)but-2-enoic acidSunitinib N-oxideAminopyrineMephedronePyridineVal-Val-Phe5,6,7,8-Tetrahydro-2,4-dimethylquinolineLys-His(S)-2-Propylpiperidine2-PhenylglycineTyr-Trp-LeuCyprodinilEinecs 234-275-5Asn-ValLovastatin4-(Methylamino)butanoic acidFusicocca-1,10(14)-diene-8beta,16-diol10-Hydroxymyristic acid methyl ester(1S,2S,4R,8R)-p-Menthane-1,2,8,9-tetrol1-(2,2-Difluoroethyl)piperazineL-Carnitine15-oxo-5S,6R-dihydroxy-7E,9E,11Z-eicosatrienoic acid13-Hydroxy-6-(1-hydroxyethyl)-12,14-dimethyl-3-methylidene-15-nonyl-9-propan-2-yl-1-oxa-4,7,10-triazacyclopentadecane-2,5,8,11-tetroneMet-ThrConcanamycin aAdenosineN-palmitoyl phenylalaninePargyline hydrochloride2-[2-(1H-imidazol-5-yl)ethyl]guanidineThalfinePro-IleAconitic acidOxyphenonium2'Deoxy-thymidine-5'-diphospho-alpha-D-glucose(-)-AllantoinL-PhenylalanineApoatropinN-dodecanoyl-L-Homoserine lactone-3-hydrazone-fluoresceinPS(16:0/22:5(7Z,10Z,13Z,16Z,19Z))3-MethylthiofentanylEpoxypheophorbide aOleyloxyethylphosphorylcholineAla-Lys-Gly-Lys-Ser13,14-dihydro-15-keto-tetranor Prostaglandin F1beta2,4,5,6(1H,3H)-Pyrimidinetetrone,5-[2-(2-chlorophenyl)hydrazone]5-(3,5-Dinitrophenyl)-1,3,4-thiadiazol-2-amine2-Methylpropanal oximeN-Acetyl-L-tyrosine17-Hydroxypregna-4,6-diene-3,20-dioneCarbendazimIle-Glu-Val-His-GlyCarbaprostacyclin-biotinL-alanyl-L-glutamate(1-)OrmetoprimAvobenzone3-(1,2-dihydroxybut-3-en-1-yl)-1H-isochromen-1-one1,26-DicaffeoylhexacosanediolTelmisartan(1S,4aS,10aR)-6-[(4bS,8S,8aR)-8-carboxy-2-hydroxy-4b,8-dimethyl-1-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthren-3-yl]-7-hydroxy-1,4a-dimethyl-8-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylic acidLys-Lys-Thr1-Oleoyl-2-myristoyl-sn-glycero-3-phosphocholinePhenylacetaldehydeLys-Pro-Ile1,28-Dicaffeoyloctacosanediol1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine3-Chloro-4-hydrazinophenylmethylsulfonylmethyl sulfone19-OxoandrostenedioneBluensidine 6-phosphateArg-Gly-ThrBufotalin1-Methylnicotinamide2-hydro-beta-NAD1-[8-[(2S,3R,4S,5R,6R)-3,5-dihydroxy-6-(hydroxymethyl)-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-1-hydroxy-3-methylnaphthalen-2-yl]ethanone2,3',4,5'-TetramethoxystilbeneAncitabine5-CHOLESTAN-3-OL-6-ONELPC(16:0/0:0)(20S)-3beta-(Tigloylamino)-20-(methylamino)-16alpha,17alpha-epoxy-5alpha-pregna-2-ene-4-onePE-NMe2(20:1(11Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))NCGC00384622-01_C34H42O14_(1S,2S,4S,5R,6R,7S,9R,12R)-12-Acetoxy-6-(acetoxymethyl)-2-hydroxy-2,10,10-trimethyl-5-[(2-methylbutanoyl)oxy]-11-oxatricyclo[7.2.1.0~1,6~]dodecane-4,7-diyl di(3-furoate)Ser-Arg-SerCarnitine C20:53,5-Ethano-3H-pyrrolo[2,3-d]carbazole, 4-ethylidene-1,2,3a,4,5,6,6a,7-octahydro-7-methyl-Thr-Phe-Leu-Thr-GlnGly-Ala-Trp1-Octadecylglycerone 3-phosphateMethanone, (1-pentyl-1H-indol-3-yl)(4-propyl-1-naphthalenyl)-PipercidePipecolic acidRanolazinePikromycin(1+)3'-Keto-3'-deoxy-AMPCarnitine C5:1Ile-Phe-Val-LysCarnitine C5:0Ala-Asp-Arg-ArgNeurosporaxanthinTrichlormethine2,5,8,11-Tetraoxatridecan-13-olThr-Thr-Gly-Leu-IleLeu-Tyr-Phe-LysMet-PheHis-Leu-LeuSulfanilamideCarnitineGeranic acidUnii-73hdp58zfkHexazinoneVal-Ile-Leu-AspPE-NMe(18:1(9Z)/18:1(9Z))Limonin 17-beta-D-glucopyranosideAgroclavinePro-His-Phe-Asp-LysUNII-UGX4BO6MOQ component RJIVUFYDGYNSNE-IZKDVACGSA-NThrombin Receptor Activator for Peptide 5 (TRAP-5)Testosterone enanthateCyclopentanethiolMet-Trp-SerLys-Val-SerCarmichelineAla-Lys-Tyr2',3'-DIDEOXYCYTIDINECarbimazolePhysostigminePalonosetronGoshonoside F2Tamsulosinn,n,n-TrimethylethenaminiumGln-Lys-LeuLeu-Gly-Gly-His-LeuGlycopyrronium bromide2-phenyl-N-4-pyridinylcyclopropanecarboxamideSelenodiglutathioneGlu-Phe-Leu-LysPA(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))ErgocristinePC(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z))(2R,3R,4S,5S,6R)-2-[3-[2-(3,4-dimethoxyphenyl)-7-methoxy-1-benzofuran-5-yl]propoxy]-6-[[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxymethyl]oxane-3,4,5-triolZapotidineProbucol2-HydroxybenzaldehydeHexadecanal-d5N-Cyclobutylmethyl-14-hydroxydihydronormorphine(1-Heptyl-5-phenyl-1H-pyrrol-3-yl)-1-naphthalenylmethanonealpha-PyrrolidinovalerophenoneCys-Leu-Ile2-Piperazin-1-ylnicotinamidePyridoxal16alpha-Hydroxydehydroepiandrosteronegamma-ConiceineAla-Val-Lys-ArgIsopropyl methyl sulfidePentoxifyllineHydroxyecdysoneForskolinB-PentasaccharideZizyphine FPhe-Lys-Leu-Arg1-Stearoyl-2-arachidonyl-sn-glycero-3-phosphocholinePralidoximumTetramethylsilane2-Undecyl-thiazolidine-4-carboxylic acidTrp-Leu-MetTangeraxanthinRhoifolinDiammonium ethylenebis(dithiocarbamate)deferrioxamine G4-Methyl-2,3-pentanedioneCarnitine C6:1Fusicocca-1,10(14)-diene-3,8beta,16-triolCarnitine C6:0EthacridineBenzoylagmatineSecoisolariciresinolMenaquinone 62-thio PAFPE(P-18:0/20:3(8Z,11Z,14Z))DopamineC24:1 SphingomyelinTamoxifenArg-Cys-SerTestosteronePro-leu(8S,9S,10R,11R,13S,14S,17R)-17-acetyl-11,17-dihydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-oneL-ValineUrsinoic acid3-Oxo-octanoic acid (2-oxo-tetrahydro-furan-3-YL)-amide1,5-Dihydro-5-methyl-1-beta-D-ribofuranosyl-1,2,5,6,8-pentaazaacenaphthylen-3-amine2-[4-Chloro-6-(4-phenylanilino)pyrimidin-2-yl]sulfanyloctanoic acidCrotonic acidAzithromycinOctapropylene glycolSinapic acidMinoxidilDiaveridine(4E,8E,12E,16E)-2,3,7,11,15-pentahydroxy-4,6,8,10,12,14,16-heptamethyloctadeca-4,8,12,16-tetraenoic acidOxiglutationeAntanapeptin AAntanapeptin CTau-fluvalinateTrimipramine3'-Hydroxy Repaglinide(Mixture of Diastereomers)ErythromycinLPC(0:0/22:5)3,6,9,12,15,18,21-Heptaoxatricosane-21,23-diolArachidonoyl-1-thioglycerolCetrimonium bromide(2-{5,7-dihydroxy-4-oxo-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-2-(2,4,5-trihydroxyphenyl)-4H-chromen-8-yl}-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl)oxidanesulfonic acid4-[2-(5-Carboxy-2-hydroxy-3-methoxyphenyl)-2-oxoethylidene]-2-hydroxy-2-pentenedioateL-Histidine hydrochloride hydrateNomilinic acid 17-glucosideLeu-Ser-Glu-Lys-Tyrp-Coumaroylagmatine17-keto-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic AcidDiosmin(Lys8,Lys9)-Neurotensin (8-13)Bepridil1-tert-butyl-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine4-Formyl-2-hydroxybenzoic acidHarmalineL-Glutamic acid2-Amino-5-bromobenzonitrileMalonobenCanrenoneAcetoinBullatalicinArginyl-glycyl-aspartic acidMantabegronCalpeptin(3-exo)-3-[3-Methyl-5-(1-methylethyl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]octane[(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] (2S)-2-[methyl(propanoyl)amino]propanoatetetrahydrozoline9'-Carboxy-alpha-tocotrienol14,15-Leukotriene C4(ExC4)1-(Ammoniomethyl)cycloheaxaneacetate(S)-AcetoinVitamin EVal-Lys-ValDiethylstilbestrolNorbadione AL-PhenylalaninolTyr-Lys-Arg-GluTyramine2-Methyl-3-pentenoic acid1-(1Z-Octadecenyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolaminePhe-Gln-Phe-Phe-LysMethyl thieno[3,2-d]thiadiazole-6-carboxylate(Z)-3-[4-acetyloxy-5-(4,10-dihydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl)-8-hydroxy-7-methoxycarbonyl-3-methyl-3,4-dihydro-1H-isochromen-6-yl]-2-methoxyprop-2-enoic acidMustard gasSer-Val-Ile7(1)-Hydroxychlorophyllide a1-Phthalazinamine, N-(3-chlorophenyl)-4-phenyl-Pro-Lys-Glu1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphateMedrysone{2-[5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-4H-chromen-8-yl]-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl}oxidanesulfonic acidSulfamethoxazoleN'-nitrosonornicotine1,9-NonanedithiolArg-Val-Tyr-Phe-PheHydroxyphenyllactic acidSalicylic acid[(1S,4aS,5aR,6S,10aS)-6'-methoxy-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-yl] acetate11beta-Hydroxyprogesterone2-octyl-1H-benzimidazoleL-Argininosuccinic acidOleandomycin(1+)4-Dodecyloxy-2-hydroxybenzophenoneN-hexacosanoylsphingosineMarmesinDisoglusideCholine3-O-alpha-mycarosylerythronolide BTetrahydro-2-furanmethanol2,3-DihydrobenzofurandTDP-4-dehydro-alpha-D-xylose(x)-2-Heptanol glucosideCapsidiolEthanaminium, 2-((3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)-N,N,N-trimethyl-4-Pentenoic acidPhe-Val-TrpRepaglinide aromatic amine2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acidAnilineLys-Phe-Lys-Met-Lys(S)-(-)-2-(Diphenylmethyl)pyrrolidineHis-Ile-Arg-GluIle-Val-PheHis-Cys-LeuUndecane9alpha,11alpha,15R-Trihydroxy-17-phenyl-18,19,20-trinor-prost-5Z-en-1-oic acid, isopropyl esterGly-Leu-Arg-Val-PheAcetylagmatineLeu-Ile-TrpThr-Ser-AsnPS(15:0/24:1(15Z))ExemestanePsammaplin A(1S,4R)-1,7,7-trimethylbicyclo[2.2.1]heptane-2,3-dioneL-Histidine,L-lysyl-Glutaminylalanine1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamineLys-Thr-Leu-Thr-GlyTrandolapril-d5 DiketopiperazineLys-Ile-His1-Hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphatePE(14:0/18:3(6Z,9Z,12Z))alpha-ObscurineSibutramineFesoterodineL-IsserineLeu-SerGly-Phe-Ile-Ser-ArgVal-Gln(1S,4S,5'R,6R,7S,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-piperidine]-16-olO-Acetyl-L-homoserine hydrochlorideClonidineEpsilon-caprolactam1-(9Z-hexadecenoyl)-2-(9Z-tetradecenoyl)-glycero-3-phosphateThr-Lys-Ala-Val-CysPro-Phe-ThrAtazanavir1-Cinnamoylpiperidine12-Methoxy-8,11,13-abietatrien-20,11-olideN-(N-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamineCimetidineDiprogulic Acid3-Guanidinopropionic acidDehydro-4-methoxycyclobrassinin4-Methoxybutyrfentanyl1-Heptadecanoyl-sn-glycero-3-phosphocholine(S)-AtpaThr-Lys-Ser-LysAlfentanil(3aR,4S,5R,6aS)-5-Hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-oneMethyllycaconitine Perchlorate, Delphinium sp.S-farnesylcysteine1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamineMilneb5(6)-EpETE methyl ester3-Hydroxy-4-deoxypaxillineVal-Thr-Arg-Arg6-[4-(5,7-dihydroxy-6-{4-hydroxy-6-methyl-5-oxo-3-[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy]oxan-2-yl}-4-oxo-4H-chromen-2-yl)phenoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid3-Hydroxy-2-iodo-4-methoxybenzaldehydeApicaStearoylcarnitineN-CyclohexylhydrazinecarbothioamideSialyllacto-N-tetraose bN1,N12-DiacetylspermineLys-Asn-Arg2,4-Dihydroxy-3,6-dimethylbenzoic acidHistidylproline(+/-)-Ethyl 2-hydroxy-2-methylbutyrate1-O-Hexadecyl-2-arachidonoyl-sn-glycero-3-phosphocholineArginyl-ValineNicotinic acid adenine dinucleotidePhenylglyoxylic acidThr-Gln-Leu-LysGlutamylglutamineMethyl glycyrrhetateUroporphyrin IIIL-Proline1-MethylxanthineLeu-Asn5-(Pentadeca-8,11,14-trien-1-yl)resorcinolDimethindeneAconitan-14-one, 7,8-dihydroxy-20-ethyl-4-(((2-(3-methyl-2,5-dioxo-1-pyrrolidinyl)benzoyl)oxy)methyl)-1,6,16-trimethoxy-, (1-alpha,4(S),6-beta,16-beta)-Polyoxyethylene 40 monostearateAminosalicylic AcidCyclic guanosine monophosphate1-((2S,3R,4S,5S)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dioneLeucinic acidDiisodityrosineLys-Tyr-ArgN-pentadecanoyl-L-Homoserine lactoneDicyclohexylamineJWH 210-d92-chloro-1-[(2S,3S,5S,10S,13S)-3-hydroxy-10,13-dimethyl-2-morpholin-4-yl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanonedTDP-3-O-methyl-4-oxo-2,6-dideoxy-L-mannoseTriethylene glycol monomethyl etherSer-Glu-Asn[(2S)-2,3-bis(3,7,11,15-tetramethylhexadecoxy)propyl] [(1S,2R,3S,4S,5R,6R)-2,3,4,6-tetrahydroxy-5-phosphonooxycyclohexyl] hydrogen phosphateCbdhq1-((3-Bromophenyl)sulfonyl)pyrrolidineThr-Val-MetCannabidiol dimethyl etherBenzene, 4-ethenyl-1,2-dimethyl-Taxa-4(20),11-dien-5alpha-olTyr-Phe-Asp-ArgOxybuprocaine4-PropylphenolCyanidin 3-(3'',6''-dimalonylglucoside)Hexenal, 4-hydroxy-CoronatineDioleoylphosphatidylcholine2-[Octahydro-4,7-dimethyl-1-oxocyclopenta[c]pyran-3-yl]nepetalactamalpha-D-Galactose 1-phosphateHis-Val-Leu-LysHistidylalanine7-Deazaadenosine6-(4-carboxy-3-hydroxy-2-methoxyphenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acidm-DichlorobenzeneGuanosineSinapyl alcohol4-Nitrophenyl phthalimidoacetate2-Cyclohexyl-2-hydroxy-2-phenylacetic acid3,6-Dideoxy-D-xylo-hexose26-HydroxybrassinolideDyclonine hydrochlorideExalamideLys-Tyr-Val-Lys3-MethylxanthinePiracetam2-AminomethylpyrimidineEuscaphic acidLeu-Tyr-Ser-Lys-SerDL-Carnitine hydrochloridePA(18:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))Cromolyn sodiumCholest-5-en-3-ol (3beta)-, decanoate[(2R,3S,6R)-6-[[(1S,2R,5S,7R,9R,10S,14R,15S,19S)-19-ethyl-14-methyl-13,21-dioxo-7-[(2R,3R,4R,5S,6S)-3,4,5-trimethoxy-6-methyloxan-2-yl]oxy-20-oxatetracyclo[10.10.0.02,10.05,9]docosa-3,11-dien-15-yl]oxy]-2-methyloxan-3-yl]-dimethylazaniumCholine AlfoscerateAnamorelin2'-Adenylic acidFlumethasone pivalate18-AMINOABIETA-8,11,13-TRIENE1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphateSpinosyn API-103N-Acetyl-DL-tryptophanSpinosyn DIsovanillic acidCyanidin chlorideNorbormide2,6,10,14-Tetramethyl-16-(5-methyl-3,6-dioxo-1,4-cyclohexadiene-1-yl)-2-hydroxy-6,10,14-hexadecatriene-3-one1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)Ser-Gln-Tyr-LysAngiotensin IVIsopentenyladenine3-Benzoyloxy-6-oxo-12-ursen-28-oic acid2-Deoxystreptidine(1S)-Deltamethrin1-(9Z-tetradecenoyl)-2-(9Z-hexadecenoyl)-glycero-3-phosphocholine[(2R,3S,4S,5R)-6-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-[[(E)-2-methylbut-2-enoyl]oxymethyl]-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-3,4-dihydroxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]methyl (E)-2-methylbut-2-enoateLeu-Phe-Lys1-Palmitoyl-2-thiopalmitoyl phosphatidylcholineFasciculic acid CIsoniazid1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholineLeelamineCrotetamideCarindone3-Methyl-L-histidine(2S)-2-amino-5-(1-aminobutylideneamino)pentanoic acidHomoormosanine{2-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-4H-chromen-6-yl]-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl}oxidanesulfonic acidAstragaloside IV2,2-DiphenylglycinePA(18:1(9Z)/22:2(13Z,16Z))FE-Coproporphyrin IIIArg-Trp-HisVeliparibBrexpiprazoleDemethyloleuropein1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholineAla-Pro-Arg-Lys-LysBetamethasone 9,11-EpoxideArg-Leu-Arg-Glu-LysProsapogenin A4-HydroxydebrisoquineNCGC00380724-01_C28H47NO8_(3R,5R,6S,7S,9R,11E,13S,14R)-14-Ethyl-13-hydroxy-3,5,7,9,13-pentamethyl-2,4,10-trioxooxacyclotetradec-11-en-6-yl 3,4,6-trideoxy-3-(dimethylamino)-D-xylo-hexopyranosideThiotepa5-(2-Chloro-benzyl)-thiazol-2-ylamineLys-Val-Val-Ala-Gly3-(4-methoxyphenyl)oxirane-2-carboxylic AcidAstragaloside IIN-Stearoyl TaurinePheniramineTetraethylene glycol1,3-Diphenylpropan-1-olAcetylsalicylic acid(2'S)-Deoxymyxol 2'-(2,4-di-O-methyl-alpha-L-fucoside)His-Arg-Lys-GluHexapropylene glycol2,6-Dihydroxybenzoic acid(4'Z,7'Z,10'Z,13'Z,16'Z,19'Z)-4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid, diester with 1,2,3-propanetriolMianserinPhenthoateCarnitine C2:0O-Decanoyl-L-carnitine1-Docosanoyl-sn-glycero-3-phosphocholineMedetomidine hydrochlorideOrphenadrine[(2R,3R)-5,7-dihydroxy-2-[3,4,6-trihydroxy-5-oxo-8-[(2R,3S)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]benzo[7]annulen-1-yl]-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoateLys-Lys-Leu-Ala-GlyAspidospermineGln-Tyr-Thr-Lys5-Aminopentanoic acidCoproporphyrin IIITiropramideBismuth subcitrate1H-Indole-2-carboxylic acid, 1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydro-, (2S,3aR,7aS)-Propyzamide2-[[(2S,3S)-2-[acetyl(methyl)amino]-3-methylpentanoyl]amino]-N-[(2S,3R)-3-hydroxy-1-[[4-methyl-1-(2-methyloxiran-2-yl)-1-oxopentan-2-yl]amino]-1-oxobutan-2-yl]-3-methylpentanamideFosfosalVinaginsenoside R12HistidinalDihydrobiopterinLeu-Leu-Ile-His-GluGalantamine14,19-DihydroaspidospermatineFarnesyl-5,7-dihydroxy-4,6-dimethylphthalide(2S,3S)-trans-2,3-Dihydro-3-hydroxyanthranilic acidPrenyl formate(E)-3-DecenolviloxazineFlupirtineAsn-Lys-ArgL-AlaninedTDP-5,5-di-C-methyl-beta-L-lyxoseNimesulide3-(4-Ethoxyphenyl)-1,1-dimethylthiourea1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholinePterinProgeldanamycinPro-Tyr-GlnCarnitine C7:DCThio-THIPUndecaprenyl pyrophosphateLys-His-Ile-Leu-AlaGuinea green BGinsenoside Rh2phenylacetyl-CoA6'-Methoxycinchonan-9-olAll-trans-heptaprenyl diphosphate3,4,6-Trimethoxy-5-oxo-8-benzo[7]annulenecarboxylic acid methyl ester1-Hexacosene(-)-Pinoresinol glucoside1-Stearoyl-2-myristoyl-sn-glycero-3-phosphocholineIndole-3-lactic acidIsoquinolineLeu-Gly-LysVal-Lys-PheAvermectin B1b monosaccharideAzelaoyl PAF2,3-Benzofluorene1,2-di-(9Z-octadecenoyl)-sn-glycero-3-pyrophosphatePro-Trp-ValAliskirenC-GMP-AMPOctylamineNorethindrone3-(p-Coumaroyl)ursolic acidLeu-ArgQuercetin 3-(6''-malonylgalactoside)1-Palmitoyl-sn-glycero-3-phosphoethanolamineKarakinerythromycin D(1+)N-octanoylsphingosine 1-phosphateLeu-Gln-Ilealpha-rhamnosyl-(1->2)-beta-D-glucosyl-solanidineErythromycin BN-ethyl-N-MethylcathinoneErythromycin DNeomethymycinTestosterone glucuronidePhe-Trp-LeuArg-Thr-SerL-Threonyl-L-alanyl-L-lysineBenzylamineInosine 2'-phosphateArg-Lys-AsnCimaterol1D-myo-inositol 4,5-bisphosphateAsn-Phe-Ala-ArgAllantoin3-[2-(1-methylpyridin-1-ium-4-yl)ethenyl]-1H-indole;iodideCarnitine C7:1Tandutinib4-AminopyridineFeruloylagmatinediethyl 2,6-dimethyl-4-oxo-4h-pyran-3,5-dicarboxylateDiethyl glutarateXylometazolinePhenylpropanolamineProlyl-cysteineCiclopiroxSinapineethyl (2Z)-but-2-enoate3beta-Hydroxy-5alpha-pregnan-20-oneGlycerophospho-N-Palmitoyl EthanolamineAcivicin2alpha,3beta-Dihydroxy-28-norurs-12,17,19(20),21-tetraene-23-oic acidLeu-Ser-Gln6,8-Dimethyl-6,7-didehydroergolin-6-iumpalmyramide AN-(1H-benzimidazol-2-ylmethyl)-N-phenylamineLaurylsphingosineDeferoxamineNeoarctin B1,2-Dioleoyl-sn-glycero-3-phosphoethanolamineAsp-Ser-ArgMyxochromide S2o-Phenylenediamine{2-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-4H-chromen-8-yl]-4,5-dihydroxyoxan-3-yl}oxidanesulfonic acid(E,E)-FutoamidePro-Asp-TyrOleoyl Ethanolamide-d4Hydroxyzine pamoateSerotoninL-HomoarginineFerulic acidLeucylprolineVal-Phe-Phe-Asn-Gly4'-Fluoro-alpha-pyrrolidinobutyrophenoneHexylamine1-(7Z,10Z,13Z,16Z-docosatetraenoyl)-glycero-3-phosphateTilarginine AcetateVal-Arg-His-ArgGly-Val-Arg5-Tert-pentyl-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide2,3-Diaminopropionic acid21,22-Diprenylpaxillinetrans-4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid17-phenyl trinor Prostaglandin D2PentadecylamineD-galactaro-1,5-lactoneFenpropimorphSer-Ile-Lys-Gly-LysdTDP-4-amino-4,6-dideoxy-alpha-D-glucoseIsopentenyl pyrophosphate1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphateArg-Ser-Ser4-Nitro-m-phenylenediamineGallic acidHis-Leu-Val-Leu-ArgPLC Thio-PIP25'-Deoxy-5'-(Methylthio) AdenosineQuinineArachidonic-p-nitroaniline5-Methyl-4-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-YL]-1,3-benzenediol(7Z,9E)-heptadeca-1,7,9-trien-11,13,15-triyneIdarubicinN-Lignoceroyl TaurineGly-TrpTyr-Ile-Lys-LysUDP-N-acetyl-2-amino-2-deoxy-D-glucuronate;UDP-N-acetyl-D-glucosaminuronate;UDP-N-acetyl-2-amino-2-deoxy-alpha-D-glucuronateL-Metanephrine(2R,3S,4S,5R)-2-butoxy-2-(hydroxymethyl)oxane-3,4,5-triolAcetazolamideGerronemin BGln-Leu-LysN-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide3-Oxolanosta-7,24Z-dien-26-oic acid2-Amino-2-[2-(3-azido-4-octylphenyl)ethyl]-1,3-propanediolItopride hydrochloridePE(18:4(6Z,9Z,12Z,15Z)/18:4(6Z,9Z,12Z,15Z))6-nitrobenzo[d]thiazol-2(3H)-oneEnoxacin3,4,5-Trihydroxy-6-[1-methoxy-1,3-dioxo-3-[[3,4,5-trihydroxy-6-[5-hydroxy-3-(4-methoxyphenyl)-4-oxochromen-7-yl]oxyoxan-2-yl]methoxy]propan-2-yl]oxane-2-carboxylic acidPhe-Tyr-Leu-Leu-TyrIsobutyric aciddelta-CEHCPro-Pro-Tyr(+)-BlebbistatinPhenolsAla-Thr-Ile-LysS-Methyl-L-methionineS-(2-carboxypropyl)-CysteamineMet-Arg-SerO-acetylhomoserineISOPRENELys-Trp-LysPipamperoneRiesling acetal2-azaniumyl-3-[3,5-diiodo-4-(3-iodo-4-sulfonatooxyphenoxy)phenyl]propanoateNarbomycin(1+)Dehydrodiisoeugenol(2R,3R,4R,5R)-2-[(9R)-9,13-dihydroxytridecyl]-5-(hydroxymethyl)pyrrolidine-3,4-diolAdrenalone hydrochloridePantethineDiphenylpyraline2,5-Dimethylbenzaldehyde1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholineCytidine 2',3'-cyclic monophosphaten-(alpha-Linolenoyl) tyrosineArg-Gln-LysArachidonyl-2-chloroethylamideIsopropyl-methyl-prop-2-ynyl-amineCucurbitacin IMaltotriosePrecorrin-6xN-Methyltyraminealpha-CYCLODEXTRINPA(16:1(9Z)/22:2(13Z,16Z))(2S,3S,4S,5R,6S)-6-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-8-yl]oxy-4-hydroxy-3,5-disulfooxyoxane-2-carboxylic acidN-cyclopropyl-8-[3-hydroxy-5-(2-methyloctan-2-yl)phenoxy]octanamideProadifen1-Methyl-2-undecylquinolin-4(1H)-one1-Linoleoyl-3-docosahexaenoyl-sn-glycerolLys-Phe-Arg-LysDolichyl phosphate dianionTrp-Thr-GlyDL-Methionine methylsulfonium chlorideDigoxigenin bisdigitoxosideLeucomycin A15,7-Dihydroxy-2-phenyl-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-8-(3,4,5-trihydroxyoxan-2-yl)chromen-4-oneAflatoxin B1 diolJasplakinolideSer-Phe-AlaSumiki's acid[(1R,2R,6S,7S,8R,10S,11S,12R,14S,16S,17R,18R)-6,7-dihydroxy-8-(hydroxymethyl)-4,18-dimethyl-5-oxo-14-phenyl-16-prop-1-en-2-yl-9,13,15,19-tetraoxahexacyclo[12.4.1.01,11.02,6.08,10.012,16]nonadec-3-en-17-yl] (2E,4E)-5-phenylpenta-2,4-dienoateBamethanPyroglutamic acid2-(1-Piperazinyl)pyrimidinePentapropylene glycolSuccinylacetone1,8-Diazabicyclo[5.4.0]undec-7-ene1-Stearoyl-2-arachidonoylglycerol6alpha-Fluoropregn-4-ene-3,20-dionePE(18:2(9Z,12Z)/18:2(9Z,12Z))11β-Prostaglandin F2α4-Quinolone-3-Carboxamide Furan CB2 AgonistCP47497 C7-Hydroxy metabolite3-[(4,5-dihydro-1H-imidazol-3-ium-2-ylmethyl)(4-methylphenyl)amino]phenolate1-[(5-Amino-5-carboxypentyl)amino]-1-deoxyfructosePhe-Arg-Leu-Phe-LeuNylidrinPE(18:3(9Z,12Z,15Z)/18:3(9Z,12Z,15Z))DesmethylerythromycinPhosphoagmatineN-Acetyl-L-alanineProctolinLactateDibutyl phthalate1-Palmitoyl-2-myristoyl-sn-glycero-3-phosphocholine6,7-dihydro-5H-cyclopenta[d]pyrimidine-2,4-diamine6-phospho-2-dehydro-3-deoxy-D-galactonic acidPC(12:0/12:0)Ile-Ser-Val(1R)-1-[[(2S,3R,11bS)-3-ethyl-9,10-dimethoxy-1,2,3,4,5,6,7,11b-octahydrobenzo[a]quinolizin-5-ium-2-yl]methyl]-7-methoxy-1,2,3,4-tetrahydroisoquinolin-2-ium-6-olSpinorphin{[12-(6,11-dihydroxy-2,2,5-trimethyl-10-oxo-3,4,5,10-tetrahydro-2H-1-oxa-5-azatetraphen-4-yl)-6,11-dihydroxy-2,5-dimethyl-10-oxo-5,10-dihydro-2H-1-oxa-5-azatetraphen-2-yl]methoxy}sulfonic acid5-O-beta-D-mycaminosyl-20-oxotylonolideBaclofen10-Deoxymethymycin(1+)GlycyllysineLys-Lys-ValLys-Asn-Leu-Tyr-ThrUsnic acidalpha-Phellandrene dimerHalopemideMethylrosanilineAloxistatinDeterrolHistidinyl-LysineClopidolCys-Trp-AlaPoloxamer-188Allantoic acid5-Phenyl-1H-tetrazoleβ-AlanineCarbenoxoloneLys-Ile-IleSedenolMaclurin 3-C-(2''-galloyl-6''-p-hydroxybenzoyl-glucoside)Dodecanoic acid, trimethylsilyl ester2-Aminobenzoic acidPhe-Thr-Asn-LysSpaglumic acidDihydroevocarpine2-(4-chlorophenyl)-2,3-dihydro-1H-perimidine2-Chloroadenosine1,2-Dihexanoyl-sn-glycerolPhe-Trp-GlyEtonogestrelD-Citramalic acidPropanamide, N-(4-methylphenyl)-N-(1-(2-phenylethyl)-4-piperidinyl)-(2S)-2-azaniumylpropanoateDinoseb15-deoxy--12,14-PGJ2-d4Myxalamid ATyr-Arg-Lys-AspMethyl linolenateButyric acidPolypodine bGestodene2-Pentenoic acid, 2-methyl-, (2Z)-2-Butyne-1,4-diolN-Arachidonoyl-3-hydroxy-Aminobutyric AcidN-(2-ethyl-6-methylphenyl)hydrazinecarbothioamide1-Methyl-2-nonylquinolin-4(1H)-oneL-Allothreonine3-FluoromethamphetamineHeptapropylene glycol1,2-Dilinoleoyl-SN-glycero-3-phosphocholine1-Stearoyl-2-linoleoyl-sn-glycerolVal-Asn-His-Val-ThrLasalocid2-Isopropyl-N,2,3-trimethylbutanamideNipecotic acidButanone acid2-Deoxy-2-Acetamido-Beta-D-Galactose-4-Sulfate3,6-Diamino-10-methylacridinium1-Cyclohexyl-3-(2-ethoxyphenyl)thioureaBufoteninN-[2-(3,4-Dihydroxyphenyl)ethyl]hexadecanamide7-Hydroxycoumarinyl ArachidonateAvermectin A1b monosaccharide[5-[8-[5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-2,3-dihydrochromen-3-yl]-5,7-dihydroxy-4-oxo-2,3-dihydrochromen-2-yl]-2-hydroxyphenyl] hydrogen sulate(E)-3-[3-[[(Z)-1-Carboxy-2-(3,4-dihydroxyphenyl)ethenyl]oxy]-4-hydroxyphenyl]propenoic acid 1-[(R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] esterNagabaPro-Asp-SerN-(Chloroacetyl)allylamine2-{6-[2,4-dihydroxy-3-(3-methylbut-2-en-1-yl)benzoyl]-5-(2,4-dihydroxy-5-methoxyphenyl)-3-methylcyclohex-2-en-1-yl}-5-[(E)-2-(2,4-dihydroxyphenyl)ethenyl]benzene-1,3-diolPro-Glu-Arg-Val-LysRicininePE(22:2(13Z,16Z)/24:1(15Z))Ala-Ala-Glygamma-Butyrolactone7-Oxocallitrisic acid, methyl ester17-Hydroxypregnenedione2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-3-O-phospho-D-glyceric acid3,5-DidecanoylpyridinePE-NMe(14:1(9Z)/14:1(9Z))4-Hydroxy-L-threonine3-VinylcatecholDicyclohexylphenylphosphinePyracarbolidAllopregnanolonePG(22:5(4Z,7Z,10Z,13Z,16Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))IsophoroneProline betaineIsotretinoinMethylergonovineColfosceril palmitate1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholineporicoic acid DM(Gal1-4GlcNAc)2-SpLeu-Val{5-[8-(5,7-dihydroxy-4-oxo-2-phenyl-3,4-dihydro-2H-1-benzopyran-3-yl)-5,7-dihydroxy-4-oxo-3,4-dihydro-2H-1-benzopyran-2-yl]-2-hydroxyphenyl}oxidanesulfonic acidTetraethylammonium7-KetocholesterolDimethylsqualenebeta-Acetyldigoxin(2R)-3-sulfanyl-2-[(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenamido]propanoic acidMalabaricanoBuclizineArachidonoyl PAF C-16{6-[2-(3,4-dihydroxyphenyl)-5,6,7-trihydroxy-4-oxo-4H-chromen-8-yl]-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl}oxidanesulfonic acidTropicamidedelta-HexanolactoneParnateAcetoacetic acidCarnitine C18:1N-(1-azabicyclo[2.2.2]oct-3-yl)-1-methyl-1H-indole-6-carboxamidePhthalic acidPimpinellinDihydropicromycinL-DeoxyalliinPhe-Glu-Lys-Ala-AlaAnisoleRhamnosePC(18:3/18:3)3'-Adenylic acidOrnithinePE-NMe2(16:0/16:0)Lys-Lys-ArgTrp-Lys-Lys[2-(3,5-Dimethoxy-4-hydroxycinnamoyloxy)ethyl]trimethylaminiumUrea, N-cyclohexyl-N'-[2-(1H-imidazol-5-yl)ethyl]-DL-Arginine1H-Pyrrolo[2,1-c][1,4]thiazine(-)-SantiaguineIndol-3-yl sodium phosphateMG-132Arachidonoyl Thio-PCMethacholine chloride1-Stearoyl-2-docosahexanoyl-sn-glycero-3-phosphocholine1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoserinee-64Argatroban2-[(2-Amino-3-phenylpropanoyl)amino]-3-methylbutanoic acidPhenformintrans-3-Feruloylcorosolic acid2-docosanamidoethanesulfonic acidPyrazin-2-carboxylic acidCarnitine C3:0AuramineBiosone2-(1H-benzimidazol-2-yl)acetohydrazide4-Fluoro-2-methoxy-5-nitroaniline1,3-Diphenylpropan-2-olThr-Tyr-Asp-Arg-AsnN-OleoyldopaminePhe-Lys-His2,3,4'-Trihydroxy-4-methoxybenzophenonehydrogen trioxo[3-(1lambdachromen-1-ylium-2-yl)phenoxy]-lambdasulfanuide5-(4-Methylpiperazin-1-yl)-2-nitroanilineValeric acid2-MethylindolineArg-Arg-His-Val-Phe2-AminoindanMethoxyphenamine16alpha,17alpha-Epoxy-20-oxopregn-5-en-3beta-yl acetate10-DeoxymethymycinVildagliptinVal-His-Glu-Lys-AlaCabergolineTyrosylleucine4-Methyl-3-nitroanilineNitisinoneDihydroquercetin2,6-DimethylpyridineDynorphin B (10-13)MeperidineGuanine2-Amino-4-[(3-aminopropyl)amino]butanoic acidNivalenol4-(Isopropylamino)-2-(2-pyridyl)-2-phenylbutyramide2'-Deoxy-thymidine-beta-L-rhamnose10,11-Dihydro-12R-hydroxy-leukotriene E41-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamineCyclosulfamuronHis-Glu-Gln-LysDehydrocostus lactoneCitbismine BArg-Tyr-GluCitbismine EArg-Thr-Ala-ArgGln-Phe-Glu-Lys6-SialyllactosamineNCGC00380642-01_C26H34O7_1,1,5a,7a,9,11b-Hexamethyl-7-methylene-3,8,11-trioxo-3,5a,5b,6,7,7a,8,9,11,11a,11b,12,13,13a-tetradecahydro-1H-isochromeno[7,8-g][2]benzoxepin-12-yl acetate1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine1-[(4-Dimethylaminophenyl)methylamino]propan-2-olIle-Arg-Phe[(6S,7S,9E,12R)-12-[(E,2S,6R,7R,9R)-7,9-dihydroxy-4,6-dimethyldec-4-en-2-yl]-7,9-dimethyl-2-oxo-1-oxacyclododec-9-en-6-yl] (2E,4E,6E,8E,10E)-12,13,15-trihydroxy-2,4,6,10-tetramethylhexadeca-2,4,6,8,10-pentaenoate9,12,15-Octadecatrienoic acid 1-[(phosphonoxy)methyl]-1,2-ethanediyl esterMethyl 1-propene-1-sulfenoselenoate6'''-Deamino-6'''-hydroxyparomomycin IIDL-3-Phenyllactic acidSchleicheol 2PF-670462 free baseDigoxigenin monodigitoxosideN-arachidonoyl-O-(2-hydroxyethyl)hydroxylamine(-)-PyrifolidineGanciclovirisovaleryl-Val-Val-Sta(3xi,4xi)-Ala-Sta(3xi,4xi)-OHFlavin adenine dinucleotideTetrahydrothiophene-2-carboxylic acidalpha-CalacoreneOndansetron hydrochloride dihydrateAnandamide(10S,13S,16S,1R,9R,14R,18R)-13-ethyl-8-methyl-8,15-diazahexacyclo[14.2.1.0<1,9 >.0<2,7>.0<10,15>.0<12,17>]nonadeca-2,4,6-triene-14,18-diol(1S,2R,5S)-5-(4-aminoimidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diolPropofol Glucuronide[10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] 3-(3-methyl-5-pentylfuran-2-yl)propanoateChanoclavineAsiatic acidVardenafilN-Isobutyl-2,4,8,10,12-tetradecapentaenamideIle-Lys-GlnSer-Thr-Pro-Asp-AlaArg-Leu-Leu-Asn-LeuLys-Tyr-Val-Met-LeuKhellosidePhosphatidylserineLys-Val-Lys(2E,4E)-N-[2-(4-hydroxyphenyl)ethyl]dodeca-2,4-dienamideLolitrem BTrp-Gln-LysMesalazine1H-BenzotriazoleSaxagliptin hydrateSarcosine5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy]-4H-chromen-4-one(9R,10S,12S,13S,14R,16S,18R)-13-ethyl-8-methyl-8,15-diazahexacyclo[14.2.1.01,9.02,7.010,15.012,17]nonadeca-2,4,6-triene-14,18-diolProcaterol hydrochloride hemihydrateSorbitolTaurine3alpha-Acetomethoxy-11alpha-oxo-12-ursen-24-oic acidLys-Gly-Gln-Lys-ValArg-His-Asn-LysClobetasol propionatePramipexoleLithocholic acidArg-Arg-Asn3-CarboxypropyltrimethylammoniumVinorine2,3-Dihydroxypropyl 9-hydroxynonanoateProscillaridinBoc-Gly-OSu3-Pyridine aldoximeBromobenzeneAcetic anhydrideDiacereinPrometonPivalanilideUDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uloseuronic acidMeestrolGlycerol 1-(5-hydroxydodecanoate)3-Isobutylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione6-ketoprostaglandin E11-[(3R,5R,9S,10S,11S,13S,14S,17S)-3,11-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-hydroxyethanoneHis-Gly-Val-Asp-Lys4-MercaptopyridineS-adenosylmethionine(R)-LisofyllinedTDP-D-glucuronate1,26-Hexacosanediol diferulateL-methionine sulfoxideSyringaldehydeUDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronic acidCyclizineAmygdalinAtipamezole2-Amino-1-phenylethanol3'-N-Acetyl-4'-O-(14-methylpentadecanoyl)fusarochromanone11beta,17beta-Dihydroxy-9alpha-fluoro-17alpha-methyl-5alpha-androstan-3-onePC(O-16:0/20:3(8Z,11Z,14Z))N-MethyldioctylaminePyrazinamide2-Oxo-4-phosphonobutanoateLatanoprost4-Chloro-6-fluoro-2-(trichloromethyl)quinolinePentaethylene glycol2-Oxo-6-methylthiohexanoic acidEtilefrineAsn-Trp6-Benzylthioguaninedl-O-PhosphoserineL-Cysteinesulfinic acid(R,R)-Palonosetron[Met5,Lys6] alpha-Neo-Endorphin (1-6)2,4-Undecadiene-8,10-diynoic acid isobutylamideLeu-Leu-TrpEoxin A41-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholineAlanylarginine2-{(E)-[4-(Dipropylamino)phenyl]diazenyl}benzoic acid5-[(1S,2R)-5,9-dihydroxy-2-(2-hydroxypropan-2-yl)-10-methoxy-11-methyl-6-oxo-1,2-dihydrofuro[2,3-c]acridin-1-yl]-6,10-dihydroxy-11-methoxy-3,3,12-trimethylpyrano[2,3-c]acridin-7-onePS(22:5(7Z,10Z,13Z,16Z,19Z)/24:1(15Z))Inosinic acidPropanedinitrile, ((4-methoxyphenyl)hydrazono)-Cholesterol sulfateGlu-His[(2S)-2-[9-(3,4-dimethyl-5-propylfuran-2-yl)nonanoyloxy]-3-hydroxypropyl] 11-(3,4-dimethyl-5-propylfuran-2-yl)undecanoateIle-Val-Ile-Phe-AsnDMABA-d6 NHS esterAla-Gly-Pro-His-LysKuwanon K(1'R,2R,3S,4'S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-2-butan-2-yl-21',24'-dihydroxy-12'-[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-3,11',13',22'-tetramethylspiro[2,3-dihydropyran-6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-oneDipyridamoleGln-Ile-Val-GluN-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide1-(4-Methoxyphenyl)-4-methylpentan-3-olLeelamine HydrochlorideArg-Thr-AlaCarvedilolAla-Thr-Tyr-LysParaxanthineNicotine4-Dodecylbenzenesulfonic acidp-Toluenesulfonic acidTrimethyl sulfoniumPyridine, 2-[1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-, (E)-Gln-Phe-LeuTrimethylolpropaneFluenetilLeu-Ile-Pro-Leu-LeuVincamineLPC(18:0/0:0)25-Acetyl-6,7-didehydrofevicordin F 3-glucoside4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, (2S,3S,5R)-HomocarnosineLeu-Ile-Tyr-Thr-Asn5-Ethoxysorgoleone 3585-Bromo-2-(methylthio)pyrimidine-4-carboxylic acid1-(9Z-hexadecenoyl)-2-hexadecanoyl-glycero-3-phospho-(1'-myo-inositol)2-hydrazino-1-propyl-1H-benzimidazoleS-(5-Adenosy)-L-HomocysteineTetradecanal1,1'-[1,11-Undecanediylbis(oxy)]bisbenzenesn-3-O-(geranylgeranyl)glycerol 1-phosphate(2-)Patellamide CCinchonidinePC(O-16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))GlutamineTerpendole EIsoacitretin2-(Ethylamino)-5-(hydroxymethyl)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diolPG(i-12:0/18:2(9Z,11Z))Palmitic acid2-Fluoromethamphetamine3-Hydroxy-10'-apo-b,y-carotenalPtdIns-(3,4)-P2(1,2-dihexanoyl)3-Amino-2-oxazolidoneTalwintrans-1,2-Dihydrobenzene-1,2-diol4-PhenylsemicarbazideDizocilpineMetyraponePhe-Pro-LysGlu-Lys-PheTrypanothionePro-Val-TyrArtemisinic acid5-(3-Hydroxy-4-phenylbut-1-en-1-yl)-1-[6-(2H-tetrazol-5-yl)hexyl]pyrrolidin-2-one4-MethylpentanalDienogestalpha-HederinEthamivanMonoglyceride citratePE-NMe(16:0/16:0)1-tetradecanoyl-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholineEpirizoleEthcathinoneGly-Lys-LysMelanostatinN-Acetyltyramine2',3'-DideoxyinosineBenzanthronetrans-2-Undecen-1-olAmitriptylinoxideN-AcetylhistidineAsn-Lys-Ile4-(2-Pyridylazo)-N,N-dimethylanilineLys-SerIle-His-Arg-Argepsilon-Rhodomycin TXanthineBardoxolone methyl4-Methoxycinnamoyloleanolic acid methyl esterd-threo-PDMPTromethamine3-Amino-2-naphthoic acidalpha,beta-Dihydroxyethyl-ThDP2-Hydroxyphenylthiourea[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolan-2-yl]methyl dihydrogen phosphateIsoxsuprine3-Hydroxycyclohexanone5-HydroxymethyluracilCetylpyridinium5-(2-phenylethyl)-1H-1,2,3,4-tetrazolep-Octyloxybenzylidene p-cyanoaniline[3-Hexadecanoyloxy-2-(9-oxononanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphateCarnitine C14:3Olivetolate(2-{[3-(3,4-Dihydroxy-5-methoxyphenyl)prop-2-enoyl]oxy}ethyl)trimethylazaniumPhe-Val-Arg-Arg4,5-Dihydro-2-methylthiazole2-O-Galloylgalactaric acid16alpha,25-Dihydroxy-24-methylene-3,4-secolanosta-4(28),7,9(11)-triene-3,21-dioic acidArg-Tyr-Gln-LysCalenduloside E3-Hydroxy-19-norpregna-1,3,5(10)-trien-20-oneFluphenazineN-phenyl-4-(quinolin-2-ylmethyl)piperazine-1-carboxamidePhyllanthinL-NameGln-Ser-Tyr-Phe-Val2-AminopyrazinePiperidine1-(4-Acetylphenyl)-3-(4-chlorophenyl)ureaN-Acetylpyrrolidine(L-Prolyl)adenylateSpermidic acidIsocytosine2-(3-(1-(((4E,10E)-2,9-Dioxo-12-isopropyl-1,8-diazacyclododecane-4,10-diene-3-yl)carbamoyl)-2-methylpropyl)ureido)-3-methylbutyric acidPhosphocholine25-Hydroxyvitamin D2-25-glucuronideMedroxyprogesterone acetate1-(4-Fluorobenzyl)piperazine dihydrochlorideOpiorphinGly-Asp-AspBecatecarinMechlorethamine1,2-Distearoyl-sn-glycero-3-phosphocholine8-Cyclopentyl-1,3-dipropylxanthineAla-Trp-LeuPA(22:2(13Z,16Z)/22:2(13Z,16Z))magnesium;3-[(3R,21S,22S)-11-ethyl-16-(1-hydroxyethyl)-3-methoxycarbonyl-12,17,21,26-tetramethyl-4-oxo-23,25-diaza-7,24-diazanidahexacyclo[18.2.1.15,8.110,13.115,18.02,6]hexacosa-1,5,8(26),9,11,13(25),14,16,18,20(23)-decaen-22-yl]propanoic acid(2S,3R,4R,4aR,6aR,6bS,8aS,14bR)-2,3-dihydroxy-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicene-4,8a-dicarboxylateTyr-Leu-Ala-LysAvermectin A1a monosaccharideGamma-CaprolactoneQuinolineAdenophostin a1,2-Dipentadecanoyl-sn-glycero-3-phosphocholineSer-Lys-Phe-Leu-Lys2-BenzoxazolinoneArg-Tyr-Ile-Arg6-Hydroxyhexanoic acidEstradiol cypionateTrp-His-Thr-Ile-Ile1,2-Didecanoyl-sn-glycero-3-phosphocholinePhenol6-Carboxyfluoresceinindole-3-glycolPheophorbide a2-(2-Chloroethyl)-6-fluoro-1H-benzimidazoleCerP(d18:1/12:0)ChloroxuronCianidanol1-Methyl-4-(prop-1-en-2-yl)benzeneGlucosamineHis-Lys-Leu-Val-ValDehydrocorticosteroneN-[(3S)-Tetrahydro-2-oxo-3-furanyl]hexadecanamidePiperidine acidCys-Arg-Arg2-thioacetyl MAGEUDP-4-keto-rhamnoseWillardiines-Allylmercaptocysteinep-hydroxymexiletine2H-Pyran-2-one, tetrahydro-4-hydroxy-4-methyl-, (R)-Leu-Ala-Thr-LysDemeton-S-methylD-4-Hydroxyphenylglycine3-Isopropylbenzonitrile8-isoprostaglandin F1α17-(4-Hydroxyphenyl)heptadecanoyl adenylateGalabiosylceramide (d18:1/16:0)LPE(18:1/0:0)Hydralazine[(9R,10S,12S,13S,14R,16S,18R)-13-ethyl-14-hydroxy-8-methyl-8,15-diazahexacyclo[14.2.1.01,9.02,7.010,15.012,17]nonadeca-2,4,6-trien-18-yl] acetateMintsulfideAsp-Lys2-[(Pyrrolidinium-2-ylcarbonyl)amino]propanoateCys-Arg-AlaCytochalasin BOleoyltaurineGlu-AlaLys-Val-Ile1,2-Dipalmitoleoyl-sn-glycero-3-phosphocholine4-Chloro-2-methylphenoxyacetatedTDP-beta-L-rhodinoseHecogenin2-Methylene-4-oxopentanedioic acidGly-Arg-Ala27-O-demethylrifamycin SV(1-)Sulfamethazine17beta-[Bis(2-hydroxyethyl)amino]androst-5-en-3beta-olUridineThr-Arg-Cys2,3-Diphenyl-3-(2-pyridinyl)acrylonitrileLys-Ile-TyrNicotinamide mononucleotidePhe-Val-Lys-LysMakisterone AFentanyl4,4'-DiapolycopenedialRuscopineTriacetinGymnemic acid I3'-Carbamoyl-biphenyl-3-yl-undecynecarbamateDonepezilN-Acetyl-L-tryptophanamidegamma-GlutamylglutamateProbenecid2,6-Dichlorobenzamide2-hydroxy-1-[(17R)-3,11,17-trihydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl]ethanoneNereistoxinL-Tyrosine1-(tert-Butyl)-3-(2-((4-(diethylamino)butyl)amino)-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)urea1-Methylpyrrolidine-2-carboxylic acidTyr-Val-Tyr-Lys-ValTestosterone propionateLyngbyatoxi BPropentofyllineN-[(1R,2S)-1-hydroxy-1-phenylpropan-2-yl]tetradecanamideVal-Ile-Pro-Lys-Ser(R)-3-hydroxybutyrylcarnitine1-DeoxynojirimycinTiocarlideTyr-Arg-Leu-Ile-ValDihydro-4,4-dimethyl-2(3H)-furanoneMethyl reserpate3-AminopropionaldehydeSpermidineN-methylundec-10-enamideSer-Leu-AsnHarmalolPC(14:0/20:5(5Z,8Z,11Z,14Z,17Z))N-omega-Propyl-L-argininePA(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/20:5(5Z,8Z,11Z,14Z,17Z))Mycolactone2-Amino-3-[(3-methylbut-2-en-1-yl)sulfanyl]propanoic acidAsn-His-Ile-ArgSialyl Lewis XAvocadyne 1-acetateRauwolscinePA(22:5(4Z,7Z,10Z,13Z,16Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))Pyrovalerone5(S),6(R)-Lipoxin A4 methyl esterN1-(2-aminophenyl)-N8-phenyloctanediamidePerindopril2,3-Dihydroxy-3-methylbutanoic acid[(3S,6S)-6-[5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)chromenylium-3-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl acetateHentriaconta-3,6,9,12,19,22,25,28-octaene-16-one-15-oatePA(18:1(9Z)/22:4(7Z,10Z,13Z,16Z))Ile-Gln-LysEmetine dication2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphateCotarnine chloridealpha-PyrrolidinopropiophenoneRitalinic acidTrp-Lys-GlnFlufenoxuronCarnitine isoC4:0Carnitine C5:DCAcetyl-L-carnitineDiuronPyridoxine1-O-Hexadecyl-sn-glycero-3-phosphocholineArg-Lys-His-Arg[(1R)-1-(3-aminophenyl)-3-(3,4-dimethoxyphenyl)propyl] (2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylateNotoginsenoside JLys-Leu-GlnHexaethylene glycolMirogabalinN-[5-[5-[(3aS,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]pentyl]-7-[(1R,2S)-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopent-3-en-1-yl]heptanamideMN-25-2-Methyl derivativedTDP-4-amino-4,6-dideoxy-5-C-methyl-L-mannosePalmitic amidePyrazinemethanethiolLPE(20:3/0:0)FulvestrantNorajmalineBW 723C86 hydrochlorideAla-Pro-SerDetomidine hydrochloride4'-Carbamoyl-[1,1'-biphenyl]-4-yl methyl(3-(pyridin-4-yl)benzyl)carbamateVal-Ala-Ala[(2S)-2-hexadecanoyloxy-3-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxypropyl] (Z)-octadec-9-enoateHydantoin-5-propanoateSer-Arg-GlyJasmonic acidVal-Tyr-Gln3-Formylsalicylic acidL-Tyrosine ethyl ester1-Aminocyclopropane-1-carboxylic acid1-(Pyrimidin-2-yl)piperidin-4-amine2,3-Hexanedione5,8-Epoxy-5,8-dihydro-10'-apo-b,y-carotene-3,10'-diolArginylasparagineMalyngamide JHericenone FAspartylalanineCys-Arg-AspL-LysineMet-Arg-ValMauritine AGly-Asn-Leu-Arg-LysIle-Ser-Ser-Lys-AlaDodecanoic acidSulfanilic acidTris(2-butoxyethyl) phosphateArg-Ile(1S,4E,5'R,6R,6'R,7S,8R,10S,11R,12R,14R,15R,16S,18E,20E,22S,25R,27S,28R,29S)-22-ethyl-7,11,15-trihydroxy-6'-(2-hydroxypropyl)-5',6,8,10,12,14,16,28,29-nonamethylspiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-oxane]-3,9,13-trioneSphinganinePAz-PC7-NitroindazoleGoyaglycoside gHydroxybuprenorphine2-[(1R,5R)-5-[2,4-dihydroxy-3-(3-methylbut-2-enyl)benzoyl]-5-(2,4-dihydroxyphenyl)-3-methylcyclohex-2-en-1-yl]-1,3,5a,8-tetrahydroxy-10a-(3-methylbut-2-enyl)-[1]benzofuro[3,2-b]chromen-11-oneCarnitine C4:0SelamectinHexyl beta-D-glucopyranosidecoproporphyrinogen IIISyringetin-3-o-glucoside(20S)-2beta,4beta-Diacetoxy-3beta-(tigloylamino)-20-(methylamino)-16alpha,17alpha-epoxy-5alpha-pregnaneGly-Ile-Asp-Lys-Phe2-[[2-amino-5-(diaminomethylideneamino)pentanoyl]amino]propanoic AcidEthyl(S)-3-hydroxybutyrate glucosideNaftopidil dihydrochloride3,5,7-trihydroxy-6-methoxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-oneD-NmappdIsonicotinic acid9S-HOTrEXanthohumolC.I. Food Black 21,2-Dichlorobenzene1,5,5,8-Tetramethyl-12-thiabicyclo[9.1.0]dodeca-3,7-dieneAla-His-Thr-LysImipramineerythromycin C(1+)Glyc-ProCys-TyrLPC(18:3/0:0)6-methoxy-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-oneLys-Pro-Lys3-Methoxy-5,10-seco-5,19-cycloandrosta-1(10),2,4-trien-17-oneAsn-Ala-Lys4-Chloro-5-fluorobenzene-1,2-diamineConvolamineNCGC00385297-01_C34H41NO16_(1S,3R,13S,14S,17S,18R,19R,20S,21S,23R,24R,25S)-20-(Acetoxymethyl)-18,25-dihydroxy-3,13,14,25-tetramethyl-6,15,22-trioxo-2,5,16-trioxa-11-azapentacyclo[15.7.1.0~1,20~.0~3,23~.0~7,12~]pentacosa-7,9,11-triene-19,21,24-triyl triacetateMephentermine3-Acetoxypregn-16-en-12,20-dioneArg-Cys-GlyNevskinCitrininBimatoprost acid methyl esterAntipainLincomycinGlycolic acidFaropenem sodium15S-Hydroxy-5Z,8Z,11Z,13E-eicosatetraene-(2-biotinyl)hydrazideN-Benzoyl-L-tyrosine ethyl ester3-Methyladipic acidN-EthylacetamideGlu-gluNovamethymycin(1+)Kojic acidSecurinineChlorthiophosHeptethylene glycol1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholineHeterodendrinFerimzone5-{6-hydroxy-4-[(E)-2-{3-[6-hydroxy-3-(3-hydroxyphenyl)-2-phenyl-2,3-dihydro-1-benzofuran-4-yl]-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuran-5-yl}ethenyl]-2-phenyl-2,3-dihydro-1-benzofuran-3-yl}benzene-1,3-diolN-(1-allylcyclohexyl)-N-(2-ethyl-6-methylphenyl)amine1,3,7,8-Tetramethylxanthine1-Oxazolo[4,5-b]pyridin-2-yl-9-octadecyn-1-one[(5-{[5,7-dihydroxy-2-(3-hydroxyphenyl)-4-oxo-4H-chromen-3-yl]oxy}-3,4-dihydroxyoxolan-2-yl)methoxy]sulfonic acidAtratonN-cyclopentyl-N,N-dimethyl-3,4-bis(tetradecyloxy)-benzenemethanaminium, iodidedTDP-3-dehydro-6-deoxy-alpha-D-glucosePhytosphingosinedTDP-4-keto-2-deoxy-beta-L-xyloseBufencarbRhizoxinMethacholineMethanandamide2-AcetylpyrazineZipeprolBis[1-[(1E,3E,5Z)-1,3,5-heptatrienyl]-8-(2,3-dihydroxyphenyl)octyl] peroxideAginoside progenin1-butyl-3-methyl-1H-imidazol-3-iumAbirateroneLenticin12-Methyltridecanoic acidDrofenine{5-[3-(2,4-dihydroxyphenyl)-3-[2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-1-benzopyran-8-yl]-2-hydroxypropyl]-2-hydroxyphenyl}oxidanesulfonic acidCoumarin2-Chloro-6-methylquinolinedTDP-4-oxo-2,3,6-trideoxy-D-glucoseC12 NBD-CeramideArg-Phe-Asp4-Dimethylsulfonio-2-hydroxybutyrate17-O-AcetylnorajmalineMethyl caffeateD-glutamine5-{9,32-Dihydroxy-6,10,13,19,20,32-hexamethyl-27-methylidene-33,34,35-trioxa-22-azahexacyclo[27.3.1.1^{1,4}.1^{4,7}.0^{12,17}.0^{17,23}]pentatriaconta-10,13,22-trien-14-yl}-3-methyloxolan-2-oneGlu-Pro-Arg13(S)-HpOTrE(gamma)Phe-Tyr-Lys-ArgMethoxyphenamine hydrochloridePetunidin 3-(6''-p-coumarylglucoside)S-acetylcysteamineC22 SulfatideN6,N6,N6-Trimethyl-L-lysinePronetalolN-Nitrososarcosine3-(11,12-Dihydroxy-15,19-dotriacontadienyl)-5-methyl-2(5H)-furanone, 9CIN-(3-Hydroxypropyl)phthalimideHC-Toxin2-[(2E)-3,7-dimethylocta-2,6-dienyl]-5-hydroxy-6-[hydroxy(phenyl)methylidene]-2,4-bis(3-methylbut-2-enyl)cyclohex-4-ene-1,3-dione2-aminoethyl [(E,2S,3R)-2-formamido-3-hydroxyoctadec-4-enyl] hydrogen phosphateLeu-Leu-Asp-Leu-LeuL-Epicatechin8-ChloroxanthineKifunensineDeoxyvasicinoneAla-Ala-Ala-Arg-Phep-Coumaroyleuscaphic acid(2S,2'S)-Oscillol 2,2'-di(alpha-L-fucoside)2-Hydroxy-3-(10-methyl-2,7-dioxooxecan-5-yl)sulanylpropanoic acidMethymycin(1+)Ciclesonide6-Aminopyridine-3-carbothioamideBufexamacBenzyl n-[(2s)-4-methyl-1-[[(2r)-4-methyl-1-[[(2s)-4-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]carbamate2-Pyrrolidinone8-iso Prostaglandin A2-biotinEmopamilDibutyl disulfideEstradiol benzoateerythromycin A(1+)Primaquine1-(6-((3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dioneImipramine hydrochloride1H-Benzotriazole-5-carboxylicacidethylesterAla-Gly5-[3-(Diethylaminomethyl)-1-octylindol-5-yl]pyrimidin-2-amine1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphoethanolaminePirimicarbFialuridineTetranor-12(S)-heteArg-MetKaempferol-3-Rhamnoside-4''-Rhamnoside-7-RhamnosideAlliinPyridine-3,4-dicarboxylic acidN,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine2-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanolMetaraminol bitartrate3-(2-Aminopropyl)phenolSer-Cys-Arg2-Aminoethyl dihydrogen phosphate[1-[(1-Methylpiperidin-2-yl)methyl]indol-3-yl]-(2,2,3,3-tetramethylcyclopropyl)methanoneDihydrouracilAscochitinePC(18:3(9Z,12Z,15Z)/18:3(9Z,12Z,15Z))cotinine N-oxideSphinganine 1-phosphateCys-PheMethyl 3-methylbenzoateAsp-Lys-Ser-Cys-Ala1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamineTrp-Ala-PheMepanipyrimOzagrelVal-Pro-TrpIle-Lys-Ala-Val-HisDiisobutyl phthalate2-Phenoxyethanol(-)-Anabasine2-Aminobenzimidazole(Sulfooxy)acetic acidDipivefrin4-Phenyl-1,2,3-thiadiazoleAsclepin2-OxoarginineMethyl 2-[4a-[[9,10a-dihydroxy-3-(2-methoxy-2-oxoethyl)-1-methyl-5,10-dioxo-3,4-dihydro-1H-benzo[g]isochromen-4a-yl]sulfanyl]-9,10a-dihydroxy-1-methyl-5,10-dioxo-3,4-dihydro-1H-benzo[g]isochromen-3-yl]acetateIle-Trp-IleTyr-Arg-AspHyp-IleL-glyceraldehyde(+/-)-High Proline2-Oxo-4-phosphonobutyrate4-Azaniumyl-4,5-dihydro-1,2-oxazol-3-olate(2E)-Decenoyl-ACPdTDP-4-oxo-2,6-dideoxy-L-mannoseSaturated archaetidylinositolTrenbolone acetateAla-Ala-LysAspidoalbineNCGC00384512-01_C20H24N2O2_6'-Methoxycinchonan-9-olAla-Thr-Leu-AspThymidineEthyl 2-methylpropanoateDodecaprenyl diphosphate[(2R)-1-icosanoyloxy-3-phosphonooxypropan-2-yl] (Z)-tetracos-15-enoateMonoacetyldapsonePantetheineN-(1,3-Dihydroxyoctadecan-2-YL)-6-[(7-nitro-2,1,3-benzoxadiazol-4-YL)amino]hexanamideGluconic AcidD-Homocysteine8-PropyloxycaffeineP-DichlorobenzeneFenoterolPgp(18:0/18:2(9Z,12Z))Arg-Lys-GlnLercanidipine hydrochlorideProlyl-HistidineHis-Asn-AlaMiltefosineDamgoAsp-Arg-Tyr3-deoxy-D-threo-hex-2-ulosaric acid3'-Dephosphocoenzyme ALevocarnitine propionate2-(2-(2-Hydroxypropoxy)propoxy)-1-propanol4,5-Dihydroxynaphthalene-2,7-disulfonic acidLys-Tyr-Thr-Ser-Sertert-Butyl 3-((3S,6S,12aS)-6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino[1',2':1,6]pyrido[3,4-b]indol-3-yl)propanoatebrefeldin A1-O-Hexadecyl-lyso-sn-glycero-3-phosphocholineDiethyltoluamideEpinephrine4-Chloro-L-phenylalanine20-hydroxy-5-O-mycaminosyltylactoneMaclurin 3-C-(2''-p-hydroxybenzoyl-6''-galloyl-glucoside)Ala-Lys-LysHydrocortisone hemisuccinateLys-Ser-Thr-Leu-ThrLeu-GlyfalseClostridium butyricum ameliorates meat quality in coccidiosis-affected sheep by rescuing thiamine diphosphate-mediated glucose metabolismSheep coccidiosis, caused by Eimeria spp., is widely studied for inducing diarrhea, but its impact on mutton quality remains poorly understood. Here, we systematically investigated the effects of Eimeria infection on meat quality and the interventing role of Clostridium butyricum (C. butyricum), alongside underlying mechanisms. Results showed that C. butyricum intervention (CB-IF group) significantly improved muscle pH and water-holding capacity, and textural properties (shear force, hardness; all p < 0.05). Eimeria infection reduced serum pro-inflammatory factors (IL-1β, IL-6, IL-18, and TNF-α) and the GSH/GSSG ratio, accompanied by an elevation in the anti-inflammatory factor IL-10. Meanwhile, local immunity (IL-17 and IL-18) and catalase activity in the Longissimus dorsi were suppressed, and these impairments were partially reversed by C. butyricum intervention. Integrative metabolomics and transcriptomics revealed that Eimeria spp. infection (IF group) downregulated thiamine transporter protein SLC19A1, reducing HET-P and thiamine diphosphate (TDP) levels in Longissimus dorsi, thereby disrupting glucose metabolism pathways, including the pentose phosphate pathway, fructose and mannose metabolism, galactose metabolism. The joint analysis indicated that Longissimus dorsi muscle compensated by upregulating glycosylation-related genes (GMPPB and TSTA3) and mitochondrial oxidative phosphorylation genes (NDUFA3, NDUFA11, NDUFB11, and COX17), leading to enhanced oxidative stress. Notably, C. butyricum intervention significantly upregulated SLC19A1 expression, restored TDP/HET-P levels, rebalanced energy metabolism, and improved meat qualtiy (e.g., elevated 24h pH and redness [a*]). This study reveals a novel mechanism through which thiamine diphosphate-mediated glucose metabolism modulates meat quality in sheep infected with Eimeria spp, thereby laying a theoretical foundation for formulating targeted nutritional strategies via probiotic intervention.2026-04-272026-03-20MTBLS14093