MetaboLightsapplication/xmlftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14298/m_MTBLS14298_LC-MS_positive_reverse-phase_v2_maf.tsvftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14298/m_MTBLS14298_LC-MS_negative_reverse-phase_v2_maf.tsvftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14298/a_MTBLS14298_LC-MS_negative_reverse-phase.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14298/s_MTBLS14298.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14298/a_MTBLS14298_LC-MS_positive_reverse-phase.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14298/i_Investigation.txtprimaryOK200ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14298<p>Kyoto Encyclopedia of Genes and Genomes (KEGG) is the major public pathway related database that includes not only genes but metabolites. Metabolites were mapped to KEGG metabolic pathways for annotation and enrichment analysis. Pathway enrichment analysis identified significantly enriched metabolic pathways or signal transduction pathways in differential metabolites comparing with the whole background. Metabolic Set Enrichment Analysis (MSEA) was also used to evaluate for pathway over-representation using the MetaboAnalyst module. The Small Molecule Pathway Database (SMPDB) library was used for the analysis, and Fisher's exact test for the over representation analysis (ORA) by R package MSEAp (https://rdrr.io/github/afukushima/MSEAp/).</p>MetaboLightsPublicLiquid Chromatography MS - negative - reverse-phaseLiquid Chromatography MS - positive - reverse-phase<p>Analysis was performed were performed using an UHPLC system (Vanquish, Thermo Fisher Scientific) with a Phenomenex Kinetex C18 (2.1 mm × 100 mm, 2.6 μm) coupled to Orbitrap Exploris 120 mass spectrometer (Orbitrap MS, Thermo). The mobile phase A:0.01% acetic acid in water; mobile phase B:IPA:ACN (1:1,v/v). Column temperature, 25 . The auto-sampler temperature was 4 , and the injection volume was 2 μL.The chromatographic gradient elution program was as follows: Initially, the mobile phase was held at 99% A and 1% B for 0.5 min, followed by a linear increase to 99% B over 3.5 min (0.5–4.0 min). This ratio (1% A / 99% B) was maintained for an additional 0.5 min (4.0–4.5 min),</p><p><br></p><p>after which the gradient returned to the initial conditions (99% A / 1% B) within 0.05 min (4.5–4.55 min) and was held for 1.45 min (4.55–6.0 min) with a flow rate of 0.4 mL/min. A 6.0 min re-equilibration period was applied to stabilize the system.</p>Non-targeted metabolomics analysis of the effect of strain MR-86 on the rhizosphere soil metabolome of Saposhnikovia divaricata under different disease severity levels.Jilin Agricultural UniversityYanzhe Dingsoilmass spectrometry assay<p>The sample (100 mg ± 1 mg) was accurately weighed into a 2.0 mL EP tube using an analytical balance. Homogenization grinding beads (2 beads) and 1000 μL of extraction solution were added, followed by vortexing for 30 s. The mixture was homogenized at 35 Hz for 4 min, transferred to an ice-water bath for 5 min of ultrasonication, and this homogenization-ultrasonication cycle was repeated three times. Subsequently, the sample was incubated at -40°C for 1 h, centrifuged at 4°C (12,000 rpm, 13,800 ×g, radius 8.6 cm) for 15 min, and the supernatant was transferred to an injection vial for machine detection. For quality control (QC), 10 μL of the supernatant from each sample (when the sample size was 12) was pooled into a composite QC sample.</p>Saposhnikovia divaricatahttps://www.ebi.ac.uk/metabolights/MTBLS14298Yanzhe Ding. Jilin Agricultural University. ding18043426173@outlook.com.Zhongming Han. Jilin Agricultural University. hanzm2008@126.com.<p>The raw MS data were converted to MzXML files using ProteoWizard MSConvert before importing into freely available XCMS software. The raw data were preprocessed through a systematic pipeline: First, feature-level quality control was applied to filter out unreliable signals. Specifically, individual features with high variability (assessed by relative standard deviation, RSD/CV) were excluded to reduce technical noise. Subsequently, missing value filtering was performed to retain only those features meeting strict completeness criteria: peaks with 50% missing values within any experimental group or across all groups were preserved. For the remaining missing values, a semi-quantitative imputation strategy was adopted, where the null entries were replaced by half of the minimum detectable value per feature using numerical simulation. Finally, data normalization using total peak area.</p>Groupding18043426173@outlook.com<p>According to the classification standard for S. divaricata root rot disease severity, rhizosphere soil samples of the S. divaricata were collected from each treatment group. Gently remove the root system of the S. divaricata and shake it to remove the loosely attached non-rhizosphere soil. Then collect the soil still adhering to the root surface as rhizosphere soil samples, and use sterile forceps to remove the root system to collect the rhizosphere soil. Some of the rhizosphere soil was stored at -80°C for metabolite detection.</p>MetabolomicsThermo Scientific Vanquish UHPLC SystemSaposhnikovia divaricataS. divaricatametabolomicsuntargeted analysis70-1200Thermo Scientific Orbitrap Exploris 120SoilThermo Scientific Vanquish UHPLC SystemSaposhnikovia divaricataS. divaricatametabolomicsuntargeted analysis70-1200Thermo Scientific Orbitrap Exploris 120Soil<p>The Orbitrap Exploris 120 mass spectrometer was used for its ability to acquire MS/MS spectra on information-dependent acquisition (IDA) mode in the control of the acquisition software (Xcalibur, Thermo). In this mode, the acquisition software continuously evaluates the full scan MS spectrum. The ESI source conditions were set as following: sheath gas flow rate as 50 Arb, Aux gas flow rate as 15 Arb, capillary temperature 320, Sweep Gas: 1 Arb, Vaporizer Temp: 350, full MS resolution as 60000, MS/MS resolution as 15000, collision energy: SNCE 20/30/40, spray voltage as 3.8 kV (positive) or -3.4 kV (negative), respectively, Scan range: 70-1200 Da.</p>16-Hydroxypalmitic acid(2S,3S,9R,13R,14S,16R)-17-[(1R)-1,5-dihydroxy-1,5-dimethyl-2-oxo-hexyl]-2,3,16-trihydroxy-4,4,9,13,14-pentamethyl-1,2,3,7,8,10,12,15,16,17-decahydrocyclopenta[a]phenanthren-11-one1,1,1,1-KestohexaosePaullinic acid2,5-Di-tert-butylhydroquinoneagnuside4-hydroxy-3-[(2E,6E)-4-hydroxy-3,7,11-trimethyl-dodeca-2,6,10-trienyl]benzoic acidaurapten[(2S,3R,4R,5S,6S)-4-acetoxy-5-hydroxy-2-[[(1S,2S,4S,5S,6R,10S)-2-(hydroxymethyl)-10-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-3,9-dioxatricyclo[4.4.0.02,4]dec-7-en-5-yl]oxy]-6-methyl-tetrahydropyran-3-yl] (E)-3-(4-methoxyphenyl)prop-2-enoate[(2R,3R,4R,5R,6S)-6-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-2-[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxymethyl]-5-hydroxy-4-(3,4,5-trihydroxybenzoyl)oxyoxan-3-yl] 3,4,5-trihydroxybenzoate4-hydroxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1H-benzo[f][2]benzofuran-3-oneTiliroside(2S,3S,4S,5R,6R)-6-[[(3S,4S,6aR,6bS,8aR,9R,12aS,14bR)-9-hydroxy-4-(hydroxymethyl)-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-5-[(2R,3R,4S,5R,6S)-6-carboxy-4,5-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-tetrahydropyran-2-yl]oxy-3,4-dihydroxy-tetrahydropyran-2-carboxylic acid5-Hydroxyvalproic acid(Z)-9,12,13-trihydroxyoctadec-15-enoic acidethyl octanoate3-hydroxy-3,4-bis[(4-hydroxy-3-methoxy-phenyl)methyl]tetrahydrofuran-2-one(E)-4-[3-hydroxy-2-methyl-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxyphenyl]-2-methylbut-2-enoic acidFA 18:2+ONodakeninTetracosanoic acid3-[7-methoxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-benzofuran-5-yl]propanoic acid1-[2-(2,3-dihydroxypropoxy)-2-oxo-ethyl]heptyl 3-hydroxynonanoateGrayanotoxin IIsovanillin2-hydroxy-6-[(E)-8-hydroxypentadec-5-enyl]benzoic acidjuglone(Z)-2-octylpent-2-enedioic acid5,7,11,19-tetraoxapentacyclo[10.8.0.02,10.04,8.013,18]icosa-2,4(8),9,13(18),14,16-hexaene-9,16-diol9-Oxooctadecanoic acid(1R,2R,4S,16R,17R,20S)-2-hydroxy-13,20-dimethoxy-4,7,17,22,22-pentamethyl-5,10,21,23-tetraoxahexacyclo[18.2.1.01,17.04,16.06,14.08,12]tricosa-6(14),7,12-trien-11-one20-DeoxyingenolOctadecanedioic acid13(S)-HpODEHYPOCRELLIN Bphysalin FUrsolic acidalpha,beta-Dihydroresveratrol3-hydroxy-8-methoxy-3-methyl-2,4-dihydrobenzo[a]anthracene-1,7,12-trioneUndecanoic acid5-O-MethylvisammiosideEthyl glucuronide(-)-Hydroxycitric acid lactone9-cis-Retinoic acid13,17-dihydroxy-6-[1-(hydroxymethyl)vinyl]-16-methoxy-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),9,14,16,18-hexaen-12-one(3Z)-octadeca-3,17-dien-12,14-diyne-1,2,16-triol3-Hydroxyvaleric acid[(2R,3S,4S,5R,6R)-6-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl 4-hydroxybenzoatePhosphateGlutaric acid(2S,3R,10R,13R,14S)-17-[(1R,2R,4S)-1,2-dihydroxy-1,4,5-trimethyl-hexyl]-2,3,14-trihydroxy-10,13-dimethyl-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-oneDiferuloyl glycerol(E)-6-(1,3-dihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methyl-hept-2-enoic acidParishin E(2S,3S,4aS)-2,3,7-trihydroxy-9-methoxy-4a-methyl-3,4-dihydro-2H-benzo[c]chromen-6-onePI(18:1/18:1)5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6-dimethoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-onePentadecanoic acid9-HPODE8-hydroxy-9E,11Z,14Z-icosatrienoic acid(4aS)-6,7-dihydroxy-1,1,4a-trimethyl-3,4,10,10a-tetrahydro-2H-phenanthren-9-one(E)-4-hydroxynon-2-enoic acidXylobiose(5E)-2-heptyl-3,4,7-trihydroxy-2,3,4,7,8,9-hexahydrooxecin-10-one3,4-dihydroxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[4-(1-hydroxy-1-methyl-ethyl)cyclohexene-1-carbonyl]oxymethyl]tetrahydropyran-2-yl]oxy-benzoic acid3-(3-hydroxyoctanoyloxy)octanoic acidTerephthalic-AcidCaffeic acidArjunolic acid3-[1,1-bis(4-hydroxyphenyl)-3-oxo-3-(2,4,6-trihydroxyphenyl)propan-2-yl]-5,7-dihydroxychromen-4-oneArabinonic acid2-Hydroxypalmitic acid2-Methylcaproic acidPantothenic acidRhein(S)-3,4-Dihydroxybutyric acid (lithium hydrate)10-Undecenoic acidTRICOSANOIC ACID18¦Á-Glycyrrhetinic acidHamaudol3-Hydroxydecanoic acidPristanic acid6,8-dihydroxy-3-(10-hydroxyundecyl)-3,4-dihydroisochromen-1-oneErucic acid(1R,2R,6R,9R)-2,11,11-trimethyl-3-oxo-tricyclo[4.3.2.01,5]undecane-9-carboxylic acidCaprylic acid3,15-dihydroxyhexadecanoic acidTubuloside A3-hydroxy-2-[(Z)-oct-2-enyl]pentanedioic acid3-[(1S,2S,4aS,7S,8aR)-4,7-dimethyl-1-[(E)-prop-1-enyl]-1,2,4a,5,6,7,8,8a-octahydronaphthalene-2-carbonyl]-4-hydroxy-5-(4-hydroxyphenyl)-1H-pyridin-2-one(3S,8S,9Z)-heptadeca-1,9-dien-4,6-diyne-3,8-diol4-Allylcatechol2-[(2R,4aR,5R,8S)-4a,8-dimethyl-5-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-3,4,5,6,7,8-hexahydro-2H-naphthalen-2-yl]prop-2-enoic acidHexadecanedioic acidPhthalic acidtrans-2-Octenoic acid3-HydroxyacetophenoneMethyl 3,4,5-trimethoxycinnamatetrans-ZeatinFurostane base -2H + O-Hex, O-Hex-dHex-dHexDihydrojasmonic AcidDeacetylgedunin(2R,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6R)-6-[(2R,3S,4R,5R,6R)-6-[(2R,3S,4R,5R,6R)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2R,3S,4R,5R)-4,5,6-trihydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-tetrahydropyran-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol[(2R,3R,4R,5R,6R)-2-[[(2R,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-4,5-dihydroxy-6-methyl-3-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoateMyristic acid5-Oxooctanoic acidDigitoxin5-[(1E,3E)-hepta-1,3-dienyl]-1,2,3-trihydroxy-cyclopentanecarboxylic acidBrassicinPivmecillinam (hydrochloride)Sulfaphenazolebungeiside Cgamma-Linolenic acid5-[2-(3,4-dihydroxy-2,5-dimethoxy-tetrahydrofuran-3-yl)ethyl]-5,6,8a-trimethyl-spiro[decalin-1,2'-oxirane]-2,3-diol[(2R,3R,4S,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-3,5-dihydroxy-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]methyl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate5Z,8Z,11Z-Eicosatrienoic acidPivagabine3-hydroxybenzaldehydeBenzoic acid + 2O, O-HexPristimerinLPE(18:1(9Z)/0:0)Olivetol5,7-dihydroxy-2-methoxy-chromen-4-one3,7-Dimethyluric acid2-[2-[(2R,8aR)-1-hydroxy-2,5,5,8a-tetramethyl-3,4,4a,6,7,8-hexahydro-2H-naphthalen-1-yl]ethyl]but-2-ene-1,4-diolAtractyloside APlumbaginPimobendanTetradecyl sulfate (sodium)5-(2-hydroxy-4-methylphenyl)-6-methylheptan-2-onePrim-O-glucosylcimifugin2,3',4,6-Tetrahydroxybenzophenone5,7-Dihydroxy-4-methylcoumarin3-(2,3-dihydroxy-5-methyl-phenoxy)-5-methyl-benzene-1,2-diolGlutaconic acidPyruvate4-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[5,6-f][1,3]benzodioxol-8-oneN-AcetyltryptophanUric acidLinoleic acid2-hydroxydodecanoic acidCitreorosein8-hydroxy-9-[(2Z)-6-methyl-4-oxohepta-2,5-dien-2-yl]-4-oxatricyclo[6.2.1.01,5]undecan-3-one[(1S,2S,3R,5R,6S,8S)-6-hydroxy-8-methyl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-9,10-dioxatetracyclo[4.3.1.02,5.03,8]decan-2-yl]methyl benzoate(-)-Epicatechingallate1-hydroxy-10-isopropyl-13-(4-oxoquinazolin-3-yl)-8,11-diazatetracyclo[6.6.1.02,7.011,15]pentadeca-2,4,6-triene-9,12-dioneMatairesinolHeptadecanoic acid5-[(2R,3R,4S,5R,6R)-3,5-dihydroxy-2-(hydroxymethyl)-6-(2-phenylethoxy)tetrahydropyran-4-yl]oxy-3-hydroxy-3-methyl-5-oxo-pentanoic acid(1S,4S,5R,9S,10R,13R,14R)-5-(acetoxymethyl)-14-(hydroxymethyl)-9-methyl-tetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acidnaphthalene-1,3-diolPhenylpyruvic acidSucrose7-HydroxydihydrobotrydialStearidonic acid4,4,8-trimethyl-9-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-tricyclo[3.3.3.01,5]undec-2-ene-2-carbaldehydeCytidine triphosphate (CTP)MannoseTetradecanedioic acidTraumatic acid(12S,12aS,12bR)-4,9,12,12b-tetrahydroxy-2,11,12,12a-tetrahydro-1H-perylene-3,10-dione12,15-Dihydroxy-13-methylhexadecanoic acid(4S,5Z,6S)-5-[2-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]oxyethylidene]-4-(2-methoxy-2-oxoethyl)-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4H-pyran-3-carboxylic acid7-(2-hydroxypropan-2-yl)-1,4a-dimethyl-2,3,4,5,6,7,8,8a-octahydronaphthalen-1-olmethyl 2-[(4,6-dihydroxy-1-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)oxy]-3-formyl-4-hydroxy-6-methylbenzoatePhytanic acid(1R,3R,6R,8S,10R,12R,13S,16S,17R)-8-tert-butyl-6,12,17-trihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione(10Z,13Z)-15,16-dihydroxyoctadeca-10,13-dienoic acid4-hydroxy-3-(6-hydroxy-1-oxo-3-pentylisochromen-8-yl)oxy-6-methoxy-2-pentylbenzoic acidPachyrrhizin8-(2-hexylcyclopropyl)octanoic acidEthyl 3-hydroxybenzoatehexyl hexanoateEsculinNervonic acidAllopurinol-1-ribonucleoside4-tert-Octylphenol2-Ketobutyric acid[(2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[2-(3-hydroxy-5-oxo-tetrahydrofuran-3-yl)propoxy]tetrahydropyran-2-yl]methyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoateRoflumilast14,16-dihydroxy-4-methyl-3-oxabicyclo[10.4.0]hexadeca-1(12),13,15-trien-2-oneOctanoylcarnitine (Car(8:0))4-(4-methoxyphenyl)butan-2-one[(5E)-3,4-dihydroxy-10-oxo-2-propyl-2,3,4,7,8,9-hexahydrooxecin-9-yl] (2E,4E)-hexa-2,4-dienoateAbietic acid(2Z,6E,10Z)-12-acetoxy-10-(acetoxymethyl)-6-methyl-2-(4-methylpent-3-enyl)dodeca-2,6,10-trienoic acidMethyl HaematommateLPC(12:0)2,7,7,11,15-pentamethyl-5,12,14-trioxapentacyclo[9.8.0.02,8.04,6.013,18]nonadec-13(18)-ene-3,17-dione(2E,4E)-5-[(1S,2R,4aS,5S,8S,8aS)-5-hydroxy-3,8-dimethyl-2-[(E)-1-methylprop-1-enyl]-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]penta-2,4-dienoic acidSM(d18:1/17:0)(2S,3S,4S,5R,6S)-6-[4-(5,7-dihydroxy-3,6-dimethoxy-4-oxo-chromen-2-yl)-2-hydroxy-phenoxy]-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic acid5-hydroxy-5-isopropyl-4-methoxy-furan-2-one1,5,8-trihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-xanthen-9-one[(2S,3R,4R,5R,6S)-2-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxochromen-3-yl]oxy-4,5-dihydroxy-6-methyloxan-3-yl] 3,4,5-trihydroxybenzoate9-HODEChrysanthemic Acid2-(4-hydroxyphenyl)ethyl (E)-3-(4-hydroxy-3-methoxy-phenyl)prop-2-enoatedimethyl 4-hydroxybenzene-1,3-dicarboxylate13(S)-HpOTrEFlavin mononucleotide (FMN)Sitaxsentan (sodium)BML-284alpha-Ketoglutaric acid (alpha-KG)(Z)-2-oct-7-enylpent-2-enedioic acid2-(3-hydroxy-5-methyl-phenoxy)-5-methoxy-3-methyl-phenolRoyal jelly acid7,8-dihydroxy-4-phenyl-chromen-2-one(2Z,4E)-5-[8-hydroxy-1,5-dimethyl-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-oxabicyclo[3.2.1]octan-8-yl]-3-methylpenta-2,4-dienoic acid2-acetylbenzoic acid4-NitrophenolGrossamide or its isomer (Not validated)XylulosePyroglutamic acidMannitol3-Hydroxyoctanoic acid[3-methyl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxymethyl]oxan-2-yl]oxybutyl] 3-methylbutanoate1-Myristoyl-sn-glycero-3-phosphocholine (LPC(14:0/0:0))Noreugenin(1S,4S,5R,9S,10R,13R,14S)-5-(Acetyloxymethyl)-14-hydroxy-14-(hydroxymethyl)-9-methyltetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acid(2S,3R,5R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one2-(4-hydroxyphenyl)ethyl (1S,4aR,7aR)-4a-hydroxy-7-methyl-5-oxo-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-1,6,7,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate9-hydroxy-2,10,10-trimethyl-tricyclo[6.3.0.01,5]undec-6-ene-6-carboxylic acidSalicylic acid5-methyl-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-chromen-2-onePinocembrin-7-O-¦Â-D-glucopyranosideTricoumaroyl spermidineDodecanedioic acidD-Mannoheptulose(3aR,4aS,6R,8S,8aR,9aR)-6,8-dihydroxy-8a-methyl-3,5-dimethylene-3a,4,4a,6,7,8,9,9a-octahydrobenzo[f]benzofuran-2-one2-(4-hydroxyphenyl)ethyl (1S,4aS,7R,7aS)-7-methyl-6-oxo-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4a,5,7,7a-tetrahydro-1H-cyclopenta[c]pyran-4-carboxylate2,2-Dimethylsuccinic acidGuaijaverinLithospermic acid8a-Hydroxy-4a,8-dimethyl-3,4,5,6,7,8-hexahydronaphthalene-2-carboxylic acid[3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] 2-isopropenyl-2,3-dihydrobenzofuran-5-carboxylateManninotrioseEmodinFlavanone base + 4O, 2PrenylHexacosanoic acidcis-9-Palmitoleic acidDeoxyguanosine1-(4-hydroxy-3-methoxy-phenyl)-7-phenyl-heptan-3-onemethyl 3-[7-hydroxy-8-(1-hydroxy-1-methyl-ethyl)-11-methoxy-4,5a,9-trimethyl-1-oxo-3,6,7,8,9a,10-hexahydroisobenzofuro[5,6-b]chromen-9-yl]propanoate(E)-5-hydroxyundec-2-enoic acidAvasimibeLactate(1S,4S,5R,9S,10R,13R,14R)-14-hydroxy-5,9-dimethyl-14-(3-methylbutanoyloxymethyl)tetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acidethyl 2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylateVitexin(E)-5-(2,3-dimethyl-3-tricyclo[2.2.1.02,6]heptanyl)-2-methyl-pent-2-enoic acid2,4,6-TribromphenolIsocaproic acidNocodazole2-[(2E,5E,7E,11E)-10-hydroxy-3,7,9,11-tetramethyl-trideca-2,5,7,11-tetraenyl]-6-methoxy-3,5-dimethyl-pyran-4-oneSmyrindiolosideIndole-3-carboxaldehydeStachyoseStearic acid(1S,4S,5R,6R,9S,10R,12R,14R)-4,5,6-trihydroxy-7-(hydroxymethyl)-3,11,11,14-tetramethyl-tetracyclo[7.5.1.01,5.010,12]pentadeca-2,7-dien-15-oneDichotomitin3,4-diphenyl-2H-furan-5-one7-bromo-4-hydroxy-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-oneApigenin-7-O-glucosideJasmonic acid3,5,7-trihydroxy-2,6,6,10,14-pentamethyl-11,13-dioxatetracyclo[8.8.0.02,7.012,17]octadec-12(17)-en-16-one(E)-4-hydroxydodec-2-enedioic acid10-hydroxy-12-(1-hydroxy-1-methyl-ethyl)-4-(3-methylbut-2-enyl)-3,6,8,13-tetraoxatetracyclo[8.3.0.02,4.05,9]tridecan-7-one3-(1-methoxycarbonylvinyloxy)benzoic acid14-methoxy-3,5-dioxa-10-azapentacyclo[9.7.1.02,6.08,19.013,18]nonadeca-1(18),2(6),7,11(19),12,14,16-heptaen-9-one(Rac)-ByakangelicinPoncirin5-pentyltetrahydrofuran-2-one(2Z,6E,10E)-12-hydroxy-6,10-dimethyl-2-(4-methylpent-3-enyl)dodeca-2,6,10-trienoic acidmethyl (E)-8-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-2,6-dimethyloct-6-enoateGlutamateCarboprost (tromethamine)Heneicosanoic acid4',7-hydroxyisoflavone-7-glucoside3-Hydorxy-3-methylglutaric acid(2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-(3-carboxypropanoyloxy)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid(Z)-6-methyl-2-(4-methylpent-3-enyl)hept-2-enedioic acid4-Nitrocatechol(E)-2-(hydroxymethyl)-3-(5-isopropyl-3-oxo-4,5,6,7-tetrahydro-1H-isobenzofuran-4-yl)prop-2-enoic acidMagnesium Lithospermate B12-Hydroxystearic acidAsiatic acid(5R)-5-hydroxy-1-(4-hydroxy-3-methoxy-phenyl)decan-3-one2-Methylheptanoic acid2,6-dihydroxy-4-(2-hydroxy-1-methyl-propyl)-3-methyl-benzoic acidp-Toluquinone(4aR,6aS,9aR)-1,8,8-trimethyl-2-oxo-1,4,4a,6a,7,9-hexahydropentaleno[1,6a-c]pyran-5-carboxylic acid3-(2,3-dihydroxypropyl)-6,8-dihydroxy-isochromen-1-oneSkyrin4-OxoretinolSwertianolin(10E)-heptadeca-1,10-dien-4,6-diyne-3,8,9-triol5-[4-[(E)-3-carboxy-3-hydroxyprop-1-enyl]-4-hydroxy-3,3,5-trimethylcyclohexyl]oxy-3-hydroxy-3-methyl-5-oxopentanoic acid4-(hydroxymethyl)-2-nitro-phenol10-Hydroxydecanoic acidAzelaic acidGoniothalenolLuteolin 7-diglucuronide(2S,3S,4S,5R,6R)-6-[[(3S,6aR,6bS,8aS,12aS,14bR)-8a-carboxy-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-3-hydroxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4-[(2S,3R,4S,5R)-3,4,5-trihydroxytetrahydropyran-2-yl]oxy-tetrahydropyran-2-carboxylic acidcis-Aconitic acidAnthraflavic_acid5-[(6-benzyloxy-3,4,5-trihydroxy-tetrahydropyran-2-yl)methoxy]-3-hydroxy-3-methyl-5-oxo-pentanoic acid5-(5-methoxycarbonyl-5,8a-dimethyl-2-methylene-decalin-1-yl)-3-methyl-pentanoic acid[5-(4-amino-2-oxo-pyrimidin-1-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl phosphono hydrogen phosphate2-Linoleoyl-1-palmitoyl-sn-glycero-3-phosphoethanolamine[(2S,3S,4S,5R,6S)-6-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-3-yl]oxy-5-hydroxy-4-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy-2-methyloxan-3-yl] (E)-3-(4-hydroxyphenyl)prop-2-enoate(2R,3R,4S,5S,6R)-2-[(2E)-6-hydroxy-2,6-dimethyl-octa-2,7-dienoxy]-6-[[(2S,3R,4S,5S)-3,4,5-trihydroxytetrahydropyran-2-yl]oxymethyl]tetrahydropyran-3,4,5-triolPelargonic acid(2S,3R,5R,9R,10R,13R,14S,17S)-17-[(1R,2R)-1,2-dihydroxy-1,5-dimethyl-4-methylene-hexyl]-2,3,14-trihydroxy-10,13-dimethyl-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one13(S)-HODE(4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-4,5,6,6a,7,8,8a,10,11,12,13,14b-dodecahydro-3H-picene-4a-carboxylic acid[2-hydroxy-2-(4-hydroxyphenyl)ethyl] (E)-3-(4-hydroxy-3-methoxy-phenyl)prop-2-enoate(E)-1-[5-[(1E)-buta-1,3-dienyl]-4-hydroxyoxolan-3-yl]pent-3-ene-1,2-diolButylated hydroxytoluene2-[[2-[[(E)-[10-acetoxy-5-hydroxy-9-(methoxymethyl)-9a,11a-dimethyl-1,4,7-trioxo-2,3,3a,9,10,11-hexahydroindeno[4,5-h]isochromen-6-ylidene]methyl]amino]-3-phenyl-propanoyl]amino]-3-methyl-pentanoic acid3-hydroxy-7-[(E)-3-hydroxy-1-methyl-prop-1-enyl]-8-(3-hydroxypropanoyl)-3,6,8-trimethyl-1,2,4,4a,7,8a-hexahydronaphthalene-1-carboxylic acidfalseNon-targeted metabolomics analysis of the effect of strain MR-86 on the rhizosphere soil metabolome of Saposhnikovia divaricata under different disease severity levelsTo clarify the effect of strain MR-86 on the rhizosphere soil metabolome of S. divaricata under different disease severity levels, a non-targeted metabolomics approach was applied to analyze soil samples from the GFQ, GFZ, and MR-86etGFQ treatments.2026-04-162026-04-16MTBLS14298