MetaboLightsapplication/xmlftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14408/m_MTBLS14408_LC-MS_negative_reverse-phase_v2_maf.tsvftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14408/a_MTBLS14408_LC-MS_negative_reverse-phase.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14408/i_Investigation.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14408/s_MTBLS14408.txtprimary200OKftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14408<p>Bile acid reference standards and stable isotopes were used.</p>MetaboLightsPublicLiquid Chromatography MS - negative - reverse-phase<p>Reverse phase C18 column. Waters Acquity UPLC.</p>Safety and efficacy analysis of in vivo lentiviral gene therapy in pre-clinical ARC syndrome models.Youssef KhalilUniversity College London GOS Institute of Child Healthblood plasmamass spectrometry assay<p>6 mm punch extracted in 240 uL methanol and 60 uL H2O. Sonicated for 15 min at room temperature.</p>Mus musculushttps://www.ebi.ac.uk/metabolights/MTBLS14408Youssef Khalil. University College London. y.khalil@ucl.ac.uk.Claudiu Cozmescu. University College London. claudiu.cozmescu.15@ucl.ac.uk.<p>Data analysed by Waters targetlynx software.</p>Treatmenty.khalil@ucl.ac.uk<p>Dried blood spots from mouse. Dried overnight and stored at -20C with dessicant until analysis. </p>MetabolomicsLC-MS dataMetabolomicsMus musculusblood plasmatargeted analysisbile acidsWaters Xevo TQ MSMassLynxexperimental blankWaters ACQUITY UPLC systemtargeted metabolite profilingWaters softwareLC-MS dataMetabolomicsMus musculusblood plasmatargeted analysisbile acidsMassLynxWaters Xevo TQ MSWaters ACQUITY UPLC systemexperimental blanktargeted metabolite profilingWaters software<p>Wateers Xevo T-QS mass spectrometer with ESI. Negative ion mode. Targetted analysis.</p>falseSafety and efficacy analysis of in vivo lentiviral gene therapy in pre-clinical ARC syndrome modelsSafety and efficacy analysis of in vivo lentiviral gene therapy in pre-clinical ARC syndrome models2026-04-292026-04-29MTBLS14408