Metabolites were identified by matching the acquired MS and MS/MS spectra with public metabolite databases. Accurate molecular weight, fragment ion information and retention time were comprehensively compared to annotate candidate metabolites. Differential metabolites between two groups of supernatants were further screened.
"],"repository":["MetaboLights"],"study_status":["Public"],"ptm_modification":[""],"instrument_platform":["Liquid Chromatography MS - negative - reverse-phase","Liquid Chromatography MS - positive - reverse-phase"],"chromatography_protocol":["Liquid chromatographic separation was performed using ultra-high performance liquid chromatography.
Parameter Value[Chromatography Instrument]: Agilent 1290 Infinity LC, Vanquish UHPLC
Parameter Value[Autosampler model]: Agilent 1290 Autosampler, Vanquish Autosampler
Parameter Value[Column model]: C18 column (conventional analytical column for metabolomics)
Parameter Value[Guard column]: Corresponding C18 guard column
"],"publication":["Non-targeted metabolomics sequencing of Lactobacillus salivarius fermentation broth."],"submitter_name":["han fuzhen"],"submitter_affiliation":["China Agricultural Research Institute, Harbin Veterinary Research Center"],"organism_part":["Culture supernatant of Lactobacillus salivarius"],"technology_type":["mass spectrometry assay"],"disease":[""],"extraction_protocol":["An appropriate volume of fermentation supernatant was mixed with ice-cold acetonitrile at a fixed ratio for protein precipitation. The mixture was vortexed thoroughly and centrifuged at high speed. The resulting supernatant was collected, filtered through a 0.22 μm organic membrane, and subjected to LC-MS analysis.
"],"organism":["Lactobacillus salivarius"],"full_dataset_link":["https://www.ebi.ac.uk/metabolights/MTBLS14704"],"author":["Fuzhen Han. China Agricultural Research Institute, Harbin Veterinary Research Center. hanfuzhen216@163.com."],"data_transformation_protocol":["Raw LC-MS data were imported into professional metabolomics software for peak picking, peak alignment, retention time correction, noise filtering and normalization. Feature intensities were extracted for subsequent statistical analysis.
"],"study_factor":["Treatment"],"submitter_email":["hanfuzhen216@163.com"],"sample_collection_protocol":["Culture supernatants of two different strains of Lactobacillus salivarius were collected after fermentation. The obtained supernatants were used as test samples for subsequent metabolomic analysis.
"],"omics_type":["Metabolomics"],"study_design":["Metabolomics","AB SCIEX QTRAP 6500+","Indolelactic acid","Metabolite","untargeted analysis","Culture supernatant of Lactobacillus salivarius","experimental blank","Agilent 1290 Infinity HPLC","Lactobacillus salivarius","Ligilactobacillus salivarius"],"curator_keywords":["Metabolomics","AB SCIEX QTRAP 6500+","Indolelactic acid","Metabolite","untargeted analysis","Culture supernatant of Lactobacillus salivarius","experimental blank","Agilent 1290 Infinity HPLC","Lactobacillus salivarius","Ligilactobacillus salivarius"],"mass_spectrometry_protocol":["Mass spectrometry detection was carried out on two high-resolution mass spectrometers respectively.
Parameter Value[Scan m/z range]: 50–1200 m/z
Parameter Value[Instrument]: AB Triple TOF 6600, Thermo Scientific Orbitrap Exploris 480
Parameter Value[Ion source]: Electrospray ionization (ESI)
Parameter Value[Mass analyzer]: Time-of-Flight (TOF), Orbitrap
"],"metabolite_name":["D-myo-inositol-1,4-diphosphate","S4:18(p3:16,f1:2)","Ser-Lys","Phenylpyruvate","Ile-Thr","4-hydroxyphenylpyruvate","Corticosterone","Tartronate","sn-Glycerol 3-phosphoethanolamine","1-stearoyl-2-hydroxy-sn-glycero-3-phosphate","Soyasapogenol b base + o-hexa-pen","Ile-Lys","Poricoic acid a","Methyl hexadecanoate","4,2'-dihydroxy-3,4',6'-trimethoxychalcone","Loxistatin acid","Furostane base -1h2o -2h + 1o, o-hex, o-pen-dhex","Thr-Val-Leu","N-3,4-tridhydroxybenzamide","Pantothenol","Reserpine","5'-o-acetyladenosine","1h-indole-5-carboxylic acid, 3-(2-methyl-1-oxopropyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-","Lasalocid","Saikosaponin a","Monensin","O-Acetyl-L-serine","6,7-dihydroxycoumarin-4-acetic acid","2-oxoadipic acid","Cauloside c","2,6-di-tert-butylphenol","DL-tryptophan","D(-)-beta-hydroxy butyric acid","Cis-5-dodecenoic acid","Ampicillin","1h-imidazo[4,5-c]pyridine-6-carboxylic acid, 1-[[4-(dimethylamino)-3-methylphenyl]methyl]-5-(2,2- diphenylacetyl)-4,5,6,7-tetrahydro-, (6s)-","Leukotriene e4 methyl ester","D-galacturonic acid","Kukoamine a","NCGC00169093-01","Gln-Gly-Gln","L-methionine","Valaciclovir","Benzeneacetic acid, 3-[3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-","Glycine","Fulvestrant 9-sulfone","D-Arabinono-1,4-lactone","Maltitol","Pg 34:3","Mevalonic acid",".beta.-alanine, n-[2-(3-pyridinyl)-6-(1,2,4,5-tetrahydro-3h-3-benzazepin-3-yl)-4-pyrimidinyl]-","2-[(2r)-9-hydroxy-7-oxo-2,3-dihydro-7h-furo[3,2-g]chromen-2-yl]propan-2-yl |a-d-glucopyranoside","1-arachidoyl-2-hydroxy-sn-glycero-3-phosphocholine","1,2-dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol)","N-acetyl-l-aspartic acid","2-hydroxy-6-methylquinoline-3-carbaldehyde","Pentasaccharides (hex-hex-hex-hex-hex)","D-ribose 1-phosphate","Cis,cis-muconic acid","meso-Tartaric acid","2-(2-hydroxybut-3-en-2-yl)-3a,6,6,9a-tetramethyl-2,4,5,5a,7,8,9,9b-octahydro-1h-benzo[e][1]benzofuran-4,5-diol","Fructose 1,6-diphosphate","Suberohydroxamic acid","DL-Serine","Tetrahydrogambogic acid","Astilbin","Cinchonine","2,2'-methylene-bis(6-tert-butyl-4 methylphenol)","Pseudouridine","Astringin","Mls000863654-01!","(2s,3s,4s,5r,6r)-6-[[(2s,3r,4r,6ar,6bs,8as,12as,14br)-4-carboxy-8a-[(2s,3r,4s,5s)-3-[(2s,3r,4s,5r,6s)-3,4-dihydroxy-6-methyl-5-[(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-4,5-dihydroxyoxan-2-yl]oxycarbonyl-2-hydroxy-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid","Spirostane -2h, + 1o, o-hex-dhex, c6h9o4","1-palmitoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine","2,3-dideoxyuridine","6:3+6o fatty acyl hexoside","N-formylmethionine","Salicylamide","Pyridoxal (Vitamin B6)","Valinomycin","DL-arginine","Glycerol 3-phosphate","Anthranilic acid (Vitamin L1)","2'-deoxyuridine 5'-monophosphate","Isovaleric acid","4-pyridoxic acid","Gambogenic acid","3-(methylthio)benzoic acid","Citrate","Quillaic acid","1h-indole-3-propanoic acid","Xanthurenic acid","N(6)-((aminoethylamino)carbonyl)methylphenyladenosine","Pipemidic acid","Diflufenzopyr","2,6-di-tert-butyl-4-methoxyphenol","Soyasaponin ii","Acetylglycine","Glyceric acid","Glycine, 1,1'-(1,8-dioxo-1,8-octanediyl)bis[glycyl-","Carbamoylaspartate","21-Hydroxypregnenolone","Chymostatin","Lnfp v","Rutinose","1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphoserine","2',6'-dihydroxy 4'-methoxydihydrochalcone","Nname,cis-9,10-Epoxystearic acid","D-(+)-mannose","3-((3'-malonyl)xyl)-28-glu polygalagenin","L-threonate","Digitoxin","N-(4-hydroxyphenyl)glycine","Ornithine","Nilotinib","N-succinyl-5-aminoimidazole-4-carboxamide ribose","Malonic acid","Androsterone glucuronide","Phe-met-arg-phe-amide","D-Threitol","Serine","Indole","Proline","1-palmitoyl-2-oleoyl-phosphatidylglycerol","1-palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol)","Ethyl 4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate","D-ornithine","Isopentenyladenine","Cis-aconitate","Bafilomycin b1","Resibufogenin","D-xylose","Gly-His","Isoevernic acid","Udp-d-glucose","N-acetyl-s-farnesyl-l-cysteine","1,2-dilinoleoyl-sn-glycero-3-phospho-(1'-rac-glycerol)","L-Ascorbic acid","L-homoserine","Dihydroresveratrol","Cyclo(tyrosyl-prolyl)","Furostane base + o-hex, o-hex-hex-hex","(3r)-5-methyl-3-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[[4-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]methoxycarbonyl]hexanoic acid","Uric acid","4-imidazoleacrylic acid","Linoleic acid","L-Tyrosine","3-(cyclohexylamino)-2-hydroxy-1-propanesulfonic acid","Argininosuccinic acid","[phe2] trh","5-Amino-4-carbamoylimidazole (AICA)","P-coumaric acid","4-hydroxyphenylmaraviroc","Pro-his","DL-threonine","Sucrose","N-acetyl-l-methionine","Glucose","Astragaloside iv","Derrusnin","Fahfa 36:3","2-arachidonoyl-1-palmitoyl-sn-glycero-3-phosphoethanolamine","Erythritol","Glutathione ethyl ester","5.beta.-androst-1-en-17.beta.-ol-3-one glucuronide","Hexsose-deoxyhexose + hexsose-deoxyhexose + c20h32","3-[(cholamidopropyl)dimethylammonio]-1-propanesulfonate","Ophthalmate","Secoisolariciresinol diglucoside","2'-hydroxy-4'-methoxyacetophenone","Natamycin","3-hydroxymyristic acid","11-dehydrothromboxane b2","5'-phosphoribosyl-5-amino-4-imidazolecarboxamide (aicar)","Fidaxomycin","Rauwolscine","Bestatin","Telmisartan","1-(1z-hexadecenyl)-sn-glycero-3-phosphocholine","Ribitol","L-Iditol","5-Methyl-2-thiouridine","Pentaerythritol tetrakis(3,5-di-tert-butyl-4-hydroxyhydrocinnamate)","Lysine","Metalaxyl-m-tp cga108906","L-kynurenine","2',2'-difluoro-2'-deoxyuridine","Eicosenoic acid","Acetyl-DL-Valine","Pumiloside","Steviolbioside","Acadesine (drug)","Glutamic acid","Trehalose","Gibberellin a4","5-heptenoic acid, 7-[(1r,2r,3s,5s)-2-[(1e,3s)-3-(2,3-dihydro-1h-inden-2-yl)-3-hydroxy-1-propen-1-yl]-3-fluoro-5-hydroxycyclopentyl]-, (5z)-","(r)-2-hydroxystearic acid","Dihydroergocristine","2-hydroxyacetanilide","Galactonic acid","Arg-Gln","1,2-distearoyl-sn-glycero-3-phospho-l-serine","6,8-dihydroxy-2,2,4,4-tetramethyl-7-(3-methylbutanoyl)-9-(2-methylpropyl)-9h-xanthene-1,3-dione","Astemizole","3- quinolinecarboxylic acid, 1,4,5,6,7,8-hexahydro-4-(3-hydroxyphenyl)-7-(2- methoxyphenyl)-2-methyl-5-oxo-, 2-methoxyethyl ester","Hydroxyacetone","Kaempferol 3-o-rutinoside","Coproporphyrin iii","3-methyluridine","Udp-n-acetylglucosamine","Alpha-ketoisovaleric acid","[(2r,3s,4s,5r,6s)-6-[3,5-dihydroxy-4-[3-(4-hydroxyphenyl)propanoyl]phenoxy]-3,4,5-trihydroxyoxan-2-yl]methyl 3,4,5-trihydroxybenzoate","D-myo-inositol-2,3,5-triphosphate","2-[[7-hydroxy-1-(4-hydroxy-3,5-dimethoxyphenyl)-3-(hydroxymethyl)-6,8-dimethoxy-1,2,3,4-tetrahydronaphthalen-2-yl]methoxy]oxane-3,4,5-triol","Taurolithocholic acid","Cytidine 5'-monophosphate (CMP)","1-(1,2-dioctanoylphosphatidyl)inositol","Tricoumaroyl spermidine","Myo-inositol","(2r,3s,4s,5r,6r)-2-[[(2s,3r,4r)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxymethyl]-6-(2-phenylethoxy)oxane-3,4,5-triol","3-formylrifamycin","Perseitol","All-trans-4-hydroxyretinoic acid","Uridine 5'-monophosphate","1,2-dipalmitoylphosphatidylinositol-4,5-diphosphonate","Piriprost","1,2-benzenedicarboxylic acid","S4:16(p3:14,f1:2)","Syrosingopine","All-trans-4-ketoretinoic acid","D-turanose","Valine","Asp-Ala","1-palmitoyl-2-linoleoyl-sn-glycero-3-phospho-(1'-rac-glycerol)","Ah 135y","Gly-His-Lys","Maleamic acid","Hydroxyisocaproic acid","1,2-dioleoyl-sn-glycero-3-phospho-l-serine","N-acetylputrescine","Indole-3-acetyl-l-tryptophan","Palatinose","Cyclo[3-(2-naphthalenyl)-l-alanylglycyl-d-tyrosyl-l-arginyl-l-arginyl]","3-(galactosyl(1-2) glucuronyl)-22-ddmp soyasapogenol b","Haploside d","4-methylphenol","Citrazinic acid","Ala-asp","Orotate","Cinobufagin","5-hydroxytryptophol","Bacopasaponin c","Chenodeoxycholate","1-(1z-octadecenyl)-sn-glycero-3-phosphocholine","Pro-thr","2-cis-4-trans-abscisic acid","Buprenorphine glucuronide","[(4e)-7-acetyloxy-6-hydroxy-2-methyl-10-oxo-2,3,6,7,8,9-hexahydrooxecin-3-yl] (e)-but-2-enoate","Indole-3-carboxaldehyde","Stachyose","Stearic acid","Pe(16:1e,14-hdohe)","Propanoic acid, 2-[[1-[3-[4-([1,1'-biphenyl]-4-ylcarbonyl)-2-propylphenoxy] propyl]-1,2,3,4-tetrahydro-5-quinolinyl]oxy]-2-methyl-","Pc(16:1e,9-hode)","8z,14z-eicosadienoic acid","L-(+)-erythrulose","Pyrrolidinium, 1-[(7r)-7-(acetyloxy)-4-hydroxy-4-oxido-3,5,9-trioxa-4-phosphapentacos-1-yl]-1-methyl-, inner salt","Kanamycin a","2'-Deoxy-D-ribose","Adrenochrome","2-Hydroxy-3-methylbutyric acid","Esculetin","Thymol-beta-d-glucoside","Triacetic acid lactone","Enrofloxacin","Borrelidin","Geniposide","Polyphyllin vi","2-hydroxy-2-methylbutyric acid","Guanidinopropionic acid","O-desmethylastemizole","L-Lysine","L-Glutamate","L-dihydroorotate","Asiatic acid","Adenosine 5'-phosphosulfate","Pulchinenoside a","2-[(3r,8as)-3,4'-dihydroxy-4,4,7,8a-tetramethyl-6'-oxospiro[2,3,4a,5,6,7-hexahydro-1h-naphthalene-8,2'-3,8-dihydrofuro[2,3-e]isoindole]-7'-yl]pentanedioic acid","[dala2] .alpha.-neo-endorphin (1-2), amide","Genistein","12-Oxo-2,3-dinor-10,15-phytodienoic acid","Adenylosuccinic acid","3,4-dihydroxyhydrocinnamic acid","Hexosyl lpe 16:0","Virginiamycin component b","Oleanane -2h, +1o, 1cooh, o-hexa-hexa","Lactobionic acid","L-Arabinono-1,4-lactone","Acetic acid, 2-[4-[[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5- thiazolyl]methyl]thio]-2-methylphenoxy]-","(1r,4s,7r,8s)-7-[(2e,4e)-hexa-2,4-dienoyl]-3-hydroxy-8-[(2s)-3-hydroxy-2,4-dimethyl-5-oxo-2,5-dihydrofuran-2-yl]-5-[(2e,4e)-1-hydroxyhexa-2,4-dien-1-ylidene]-1,3-dimethylbicyclo[2.2.2]octane-2,6-dione","Leu-Arg","(+)-6-aminopenicillanic acid","Citramalate","L-pyroglutamic acid","3-nitrophenol","Thymine","Farrerol","Glycerophosphate(2)","Cytidine 3'-monophosphate","Kendomycin","4-hydroxy-l-glutamic acid","13(S)-HODE","N-Acetylglucosamine 1-phosphate","D-Ribose","Fosinopril","3,15-dibenzyl-1,4,12-trimethyl-1,4,7,10,13-pentazacyclopentadecane-2,5,8,11,14-pentone","Progesterone","N-acetyl-dl-valine","Glu-Pro","L-Aspartate","Norephedrine","Gitoxigenin diacetate","Taurine","Embelin","Ile-Asp","Allantoin","Ciclopirox .beta.-d-glucuronide","Arachidic acid","Zinniol","Formylanthranilic acid","1,7-bis(3,4-dihydroxyphenyl)heptan-3-yl acetate","O-Phosphotyrosine","1h-indole-1-pentanoic acid, 3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]-","Lewis a trisaccharide","3-hydroxy-3-methylglutaric acid","4-hydroxyatorvastatin lactone","Guanosine 3',5'-cyclic monophosphate","L-Threonine","Gamma-l-glutamyl-l-glutamic acid","1,2-dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4'-bisphosphate)","Nelfinavir","Sparfloxacin","Kynurenic acid","Adenosine 3'-monophosphate","9-phenyl-1-(2,4,6-trihydroxyphenyl)nonan-1-one","N-methyltryptamine","(e)-5-hydroxy-n-[3-[5-[3-[[(e)-5-hydroxy-3-methylpent-2-enoyl]amino]propyl]-3,6-dioxopiperazin-2-yl]propyl]-3-methylpent-2-enamide","Pyridoxal","Vinblastine","Gln-glu","Succinate","1-stearoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine","Muramic acid","Barbituric acid","Leu-Lys","Cetirizine","Hematoporphyrin","Pe(16:0e,10-hdohe)","Garcinol","Salicin","Methanone, [1-(5-hydroxypentyl)-1h-indol-3-yl](4-hydroxyphenyl)-","3-Hydroxydodecanoic acid","Kushenol f","Dtyr-Val-Gly","Cholesteryl sulfate","Selaginpulvilin o",".alpha.,.beta.-trehalose","Qingyangshengenin","2-oleoyl-1-stearoyl-sn-glycero-3-phosphoserine","Indole-3-acetyl-l-valine","D-Mannose","17-phenyltrinor-13,14-dihydroprostaglandin a2","Antipain","Ganoderic acid a","L-citrulline","Hexosyl lpe 18:3","Ammelide","1,2-dioleoyl-sn-glycero-3-phosphate","2-keto-3-deoxyoctonic acid","Quinolin-2-ol","4-Hydroxybenzoate","Inosine 5'-monophosphate","3,4-dihydroxybenzaldehyde","Shikimate","5-amino-2-(3,4'-dihydroxy-4,4,7,8a-tetramethyl-6'-oxospiro[2,3,4a,5,6,7-hexahydro-1h-naphthalene-8,2'-3,8-dihydrofuro[2,3-e]isoindole]-7'-yl)-5-oxopentanoic acid","Phenylalanine","Medicagenic acid base + o-hexa","Leukotriene d4","2-dehydro-3-deoxy-d-gluconate","Benzoic acid, 2-[3-[3-[(5-ethyl-4'-fluoro-2-hydroxy[1,1'-biphenyl]-4-yl)oxy]propoxy]-2-propylphenoxy]-","4-hydroxyvalsartan","Protodioscin","5-hydroxy-3,4-dihydro-2(1h)-quinolinone","Rebaudioside b","Dl-a-hydroxybutyric acid","Pi 36:2","Alanine-2,3,3,3-d4","L-Valine","4-thiazolidinecarboxylic acid, 2-undecyl-, (4r)-","(2s,3r,5r,10r,13r,14s,17s)-2,3,14-trihydroxy-10,13-dimethyl-17-[(2r,3r)-2,3,6-trihydroxy-6-methylheptan-2-yl]-2,3,4,5,9,11,12,15,16,17-decahydro-1h-cyclopenta[a]phenanthren-6-one","Uracil","Pi 36:4","2-docosahexaenoyl-1-stearoyl-sn-glycero-3-phosphoserine","2-[(2r,4as,8s,8as)-8-[2-[(4as,7r,8ar)-7-(1-carboxyethenyl)-1-hydroxy-4a-methyl-2-oxo-6,7,8,8a-tetrahydro-5h-naphthalen-1-yl]ethyl]-4a-methyl-7-oxo-1,2,3,4,8,8a-hexahydronaphthalen-2-yl]prop-2-enoic acid","Indolelactic acid","Rubranoside a","Fungichromin","alpha-D-Glucose 1-phosphate","3-((3'-malonyl)xyl)-28-glu-2-hydroxy oleanolic acid","Cytidine 5'-monophosphate",".beta.-nicotinamide adenine dinucleotide(NAD)","1-methylguanosine","Gamma-glutamylleucine","Ala-Gly-Ala","3-hydroxyisovaleric acid","Cytosine","N-[3-[5,17-bis[3-[acetyl(hydroxy)amino]propyl]-14-benzyl-8-(hydroxymethyl)-11-(2-methylpropyl)-3,6,9,12,15,18-hexaoxo-1,4,7,10,13,16-hexazacyclooctadec-2-yl]propyl]-n-hydroxyacetamide","Tsas#9","(19r)-9-acetyl-19-hydroxy-10,14-dimethyl-20-oxopentacyclo[11.8.0.0<2,10>.0<4,9 >.0<14,19>]henicos-17-yl acetate","4-hydroxybenzaldehyde","Furostane base -2h + 1o, o-hex, o-pen-dhex","Cis-4,7,10,13,16,19-docosahexaenoic acid","N-(2-phosphate-1r-methylethyl)-5z,8z,11z,14z-eicosatetraenamide","Norbuprenorphine glucuronide","Stauprimide","Cyanuric acid","1-oleoyl-sn-glycero-3-phosphoethanolamine","Myristic acid","[(2r,3s,4s,5r,6s)-6-[(2s,3r,4s,5r,6r)-6-[[(1s,3r,4s,4ar,8ar)-4-[(3s)-3-[(2s,3r,4r,5r,6r)-3,4-dihydroxy-6-methyl-5-[(2s,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-3-methylpent-4-enyl]-3,4,8,8a-tetramethyl-1,2,3,4a,5,6-hexahydronaphthalen-1-yl]oxy]-4,5-dihydroxy-2-methyloxan-3-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl acetate","Beclomethasone dipropionate","m-Chlorohippuric acid","Hypoxanthine","(z)-2,6-dimethyl-7-(4-methyl-5-oxooxolan-2-yl)-3-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]hept-5-enoic acid","Phenyllactic acid","Heterophyllin b","11-ketofusidic acid","Gly-Trp","Ginsenoside rb3","Adenosine 2'-monophosphate","Adenosine 5'-diphosphate","Benzoylnorecgonine","Uridine 5'-monophosphate (UMP)","Dehydrotumulosic acid","(S)-2-Hydroxyglutarate","Aclarubicin","Hymeglusin","Apigenin 7-glucoside","trans-cinnamate","2-keto-l-gulonic acid","Dibutyryl-cgmp","1-methylpseudouridine","1-oleoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol)","Isoleucine","S4:19(p3:17,f1:2)","Phe(benzoyl)-leu-arg","Phosphoramidon","Eplerenone hydroxy acid","Codeine-6-.beta.-d-glucuronide","Trp-Ala","Pyruvate","Adenine","3-aminopyrazine-2-carboxylic acid","N-acetyl-l-tyrosine","6-hydroxyhexanoate","2-ketohexanoic acid","Fructose","D-arabinose","Nicotinuric acid","Guanosine 5'-diphospho-.beta.-l-fucose","1,7-bis(3,4-dihydroxyphenyl)-6-hydroxyheptan-3-one","2-hydroxydodecanoic acid","D-quinovose","N-.alpha.-(tert-butoxycarbonyl)-l-proline","Hydroquinidine","Enalaprilat","Citraconic acid","Rifaximin","Pteropodine","Pi 38:4","3',5'-Cyclic guanosine monophosphate","Pi 38:5","11-oxomogroside v","Trans-epoxysuccinyl-l-leucylamido(4-guanidino)butane","Dimethylglycine","9R,10S-EpOME","Bufexamac","1-methoxyindole-3-carbaldehyde","2,5,7,8-tetramethyl-2-(.beta.-carboxyethyl)-6-hydroxychroman","Andrastin a","Phenylacetic acid","Dihydroxyacetone","7-ethyl-10-(4-n-aminopentanoic acid)-1-piperidino)carbonyloxycamptothecin","3,4-dihydroxybenzoic acid","Soyasaponin i","7-hydroxy-4'-methoxyflavone","Adenosine 5'-diphosphate (ADP)","Cholic acid","Palmitic acid","Gentiopicroside","Leptomycin b","Pyroglu-trp","Histidine","Leu-His","D-aspartic acid","D-gluconate","Benzoic acid, 3-[[(3-carboxycyclohexyl)amino]carbonyl]-4-[3-[4-[4-(cyclohexyloxy)butoxy]phenyl]propoxy]-","(2s,3r,4s,6ar,6bs,8as,12as,14br)-2-acetyloxy-8a-[(2s,3r,4s,5s,6r)-6-[[(2r,3r,4r,5s,6r)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-4,5-dihydroxy-3-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxycarbonyl-3-hydroxy-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicene-4-carboxylic acid","Tyramine","Propionylglycine","D-(-)-tagatose","1-octadecanoyl-sn-glycero-3-phospho-(1'-myo-inositol)","Propionic acid","Avocadyne acetate","Maltotriose","N-Acetyl-DL-methionine","Ne-acetyllysine","2-[(2-aminobenzoyl)amino]propanoic acid","Epigallocatechin gallate","(z)-5,8,11-trihydroxyoctadec-9-enoic acid","Dihydrouracil","Homocitrate","Butyric acid, 4-[(4-chloro-o-tolyl)oxy]-","Hederacoside c","2-[2-[5-[4-[4,5-dihydroxy-6-methyl-3-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxy-1,2,4a,5-tetramethyl-2,3,4,7,8,8a-hexahydronaphthalen-1-yl]-3-methylpent-1-en-3-yl]oxy-5-hydroxy-6-methyl-3-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-4-yl]oxy-6-methyloxane-3,4,5-triol","Phenylphosphonic acid","Glimepiride","Dl-lactate","L-alaninamide, n-[2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-l-valyl-n-(2-aminoethyl)-","D-lyxose","Asn-Pro","N-acetyl-o-fluoro-dl-phenylalanine","Ginsenoside f1","Pro-val","Echinocystic acid","1-myristoyl-sn-glycero-3-phosphocholine","S-adenosyl-l-homocysteine","Trp-Met","1-pentadecanoyl-sn-glycero-3-phosphocholine","2-[3-[(e)-6-acetyloxy-2-hydroxy-6-methyl-3-oxohept-4-en-2-yl]-6-(carboxymethyl)-2-hydroxy-3a,5a,9b-trimethyl-5-oxo-2,3,4,6,9,9a-hexahydro-1h-cyclopenta[a]naphthalen-7-yl]-2-methylpropanoic acid","Pseudoprotodioscin","Hydroxyhydroquinone","Indoleacetic acid",".alpha.,.alpha.'-trehalose 6-phosphate","Medicagenic acid base + o-hex","Hydroxyphenyllactic acid","Gamma-Glu-Cys","Adenosine 3',5'-cyclic phosphate (cAMP)","Alanine","3-(6'-o-malonyl)-glu-28-glu medicagenic acid","2-Methylguanosine","Levulinic acid","M-hydroxycocaine","Isomaltose","Tryptophan","Siamenoside i","Leiocarposide","Desmethylverapamil","Fa 18:4+2o","Acetyl-dl-leucine","N-acetyl-d-mannosamine","Dodecyl sulfate","Asparagine","L-gulono-1,4-lactone","Benazolin","Mycophenolic acid phenolic .beta.-d-glucoside","N-carboxyethyl-.gamma.-aminobutyric acid","Trp-Pro","Dimethachlor oa","N-alpha-acetyl-l-lysine","Labetalol","D-arabinonic acid","D-2-aminobutyric acid","Adenylyl(3'-5')cytidine","Methylmalonic acid","(9a-hydroxy-3,8a-dimethyl-5-methylidene-2-oxo-4,4a,6,7,8,9-hexahydrobenzo[f][1]benzofuran-8-yl) acetate","Maleic acid","5-(diethoxyphosphoryl)-5-methyl-1-pyrroline-n-oxide-biotin","Cis-moxifloxacin acyl-.beta.-d-glucuronide","2E-Eicosenoic acid","Nodularin","1-o-hexadecyl-2-deoxy-2-thio-s-acetyl-sn-glyceryl-3-phosphorylcholine","Pc(18:1e,14,15-eet)","N-fructosyl isoleucine","O-acetylserine","Ltc4-[d5]","Indoxyl sulfate","Cytidine 2',3'-cyclic phosphate","Terrestrosin d","Phosphorylcholine","Soyasapogenol b base + o-hexa-pen-dhex, o-c6h7o3","Swertiamarin","Pg 32:1","Terragine e","Trp-Cys","3-Hydorxy-3-methylglutaric acid","Pro-Asp","Irbesartan","4-[[4-hydroxy-2-(2-methylpropyl)-1-oxo-3,3a-dihydro-2h-imidazo[1,2-a]indol-4-yl]methyl]-1-methyl-2,4-dihydro-1h-pyrazino[2,1-b]quinazoline-3,6-dione","Indole-3-butyric acid","Isocitrate","D-Lactose","Coumarin-suberoylanilide hydroxamic acid","Pyruvaldehyde","Rifapentine","D-arabitol","Sedoheptulose","5'-CMP","D-glucarate","Gly-Asp","Pentagastrin","3-hydroxy-4-methoxybenzyl alcohol","Methionine sulfoxide","Pterine","13,14-dihydro-15-ketotetranorprostaglandin f1.beta.","D-fructose","Pyrazino[1',2':1,6]pyrido[3,4-b] indole-3-propanoic acid, 1,2,3,4,6,7,12,12a-octahydro-9-methoxy-6-(2-methylpropyl)- 1,4-dioxo-, 1,1-dimethylethyl ester, (3s,6s,12as)-","Heminordihydroguaiaretic acid","D-glucose 6-phosphate","16-hydroxyhexadecanoic acid","Taurodeoxycholic acid","Carbenoxolone","Desferrioxamine d2","Dihydrothymine","3-hydroxypyridine","5-Oxo-ETE","L-Carnosine","Urocanate","1-heptadecanoyl-sn-glycero-3-phosphocholine","16-phenyltetranorprostaglandin f2.alpha.","Met-Ile","Ser-Leu-Ile-Gly-Lys-Val-Amide","Salicyluric acid","Vindesine","Dethiobiotin","Rutin","Tartaric acid","(2e,6e,10e)-13-[(2r)-6-hydroxy-2,8-dimethyl-3,4-dihydrochromen-2-yl]-2,6,10-trimethyltrideca-2,6,10-trienoic acid","Hexadecanedioic acid, 3,3,14,14-tetramethyl-","Deoxycholic acid","N-acetylhistidine","Deacetoxy(7)-7-oxokhivorinic acid","Xylitol","Linolenic acid","Taurolithocholic acid sulfate","6-(trifluoromethyl)quinolin-4-ol","D-fructose 6-phosphate","N-acetyl-l-phenylalanine","Pi 34:2","Daidzein","Mestranol","Asiaticoside"],"additional_accession":[]},"is_claimable":false,"name":"Non-targeted metabolomics sequencing of Lactobacillus salivarius fermentation broth","description":"To conduct an in-depth analysis of which metabolites in the antiviral-effective lactic acid bacteria supernatant are playing a role, a pretreatment approach was selected. Non-targeted metabolomic analysis was performed on the differential metabolites between LSD2339-CFS and LSM231-CFS, which exhibited no antiviral effect compared to the virus-exposed group.","dates":{"publication":"2026-06-08","submission":"2026-06-07"},"accession":"MTBLS14704","cross_references":{}}