Data standardization was performed using the total spectral intensity normalization method, and metabolite identification was achieved by matching molecular ion peaks, adduct ions, and characteristic fragment ions. The final qualitative and quantitative results were validated using both the mzCloud high-resolution mass spectrometry database and the ChemSpider chemical structure database.
"],"repository":["MetaboLights"],"study_status":["Public"],"ptm_modification":[""],"instrument_platform":["Liquid Chromatography MS - positive - hilic","Liquid Chromatography MS - negative - hilic"],"chromatography_protocol":["Analysis was performed using an ultra-high performance liquid chromatography (UPLC, Shimadzu UFLC SHIMADZU CBM30A) coupled with a triple quadrupole tandem mass spectrometer (Applied Biosystems 6500 QTRAP). Chromatographic separation was performed using a Waters ACQUITY UPLC HSS T3 C18 column (100 mm × 2.1 mm, 1.8 μm). The mobile phase consisted of a binary gradient system of 0.04% acetic acid aqueous solution (phase A) and 0.04% acetic acid acetonitrile solution (phase B). The column temperature was maintained at 40 °C, the flow rate at 0.4 mL/min, and the injection volume at 2 μL.
"],"publication":["Gut Microbiota Contributes to Heat Tolerance Through Metabolic Remodeling and Suppression of Thermogenesis in Chickens."],"submitter_affiliation":["Peking University"],"submitter_name":["Duo Keai"],"organism_part":["Cecum"],"technology_type":["mass spectrometry assay"],"disease":[""],"extraction_protocol":["Cecal contents were homogenized and transferred into centrifuge tubes, and a mixture of methanol containing formic acid was added for metabolite extraction, followed by vortex mixing. Samples were centrifuged at 15,000 × g at 4 °C, and the resulting supernatants were collected for subsequent analysis.
"],"organism":["Gallus gallus"],"full_dataset_link":["https://www.ebi.ac.uk/metabolights/MTBLS14785"],"author":["Chunmei Li. Nanjing Agricultural University. chunmeili@njau.edu.cn.","Sheng Li. Nanjing Agricultural University. shengli@njau.edu.cn."],"data_transformation_protocol":["The raw data were preprocessed using Compound Discoverer 3.0 (Thermo Fisher Scientific), with a retention time window of 0.2 min and a quality deviation threshold of 5 ppm. Characteristic peak extraction criteria included: signal-to-noise ratio 3, signal strength 1×10^5, and peak area relative standard deviation < 30%.
"],"study_factor":["Group"],"submitter_email":["keaiduoduo998@126.com"],"sample_collection_protocol":["Cecal contents of FMT recipent chickens were collected and immediately snap-frozen in liquid nitrogen and stored for subsequent analyses.
"],"omics_type":["Metabolomics"],"study_design":["heat tolerance","heat stress","Metabolomics","thermogenesis","untargeted analysis","Cecum","Cyan-shank partridge chickens","Orbitrap Exploris 480","Agilent 1290 Infinity LC","gut microbiota","Cecal contents","Gallus gallus"],"curator_keywords":["heat tolerance","heat stress","Metabolomics","thermogenesis","untargeted analysis","Cecum","Cyan-shank partridge chickens","Orbitrap Exploris 480","Agilent 1290 Infinity LC","gut microbiota","Cecal contents","Gallus gallus"],"mass_spectrometry_protocol":["Mass spectrometry was performed using an electrospray ionization (ESI) source in positive ion mode. Key parameters were set as follows: ion source temperature 500, spray voltage 5500 V, and curtain gas pressure 25 psi. The declustering voltage (DP) and collision energy (CE) were optimized through preliminary experiments, and data acquisition was conducted in dynamic multiple reaction monitoring (dMRM) mode.
"],"metabolite_name":["3-Amino-4-hydroxyphenylalanine","2-Naphthyl-D-alanine","Ponceau 6","Methyl 3-(3,4-dihydroxy-5-phenyloxolan-2-yl)-3-hydroxypropanoate","Pyrocatechol","o-Hydroxyhippuric acid","Piceatannol","(3e,5s,7r,8r,11e,13s,15r,16r)-3,5,7,11,13,15-hexamethyl-8,16-bis(1,3-oxazol-5-ylmethyl)-1,9-dioxacyclohexadeca-3,11-diene-2,10-dione","Cefuroxime","5-(2,5-Dichlorophenyl)-2-furoic acid","Loxistatin acid","2-Decyl-3-hydroxypentanedioic acid","Thr-Val-Leu","10-hydroxydecanoate","Butamifos","2-Chloro-6-fluoro-1H-1,3-benzodiazole","Ergonovine",".beta.-Tocotrienol","5,6-Dihydroxyindole-2-carboxylic acid","Iminodiacetic acid","Carprofen","Glycolate","Asperuloside","2,6-Difluoro-3-[(propylsulfonyl)amino]benzoic acid","D-Psicose","Gly-Glu","1-Hydroxy-2-naphthoic acid","(+)-.gamma.-Tocopherol","Arabinose 5-phosphate","2-Acetamido-3-(4-hydroxy-3-methoxyphenyl)propanoic acid","N-Acetyl-D-tryptophan","Octanoic acid, 2-[[4-[([1,1'-biphenyl]-4-ylmethyl)amino]-6-chloro-2-pyrimidinyl]thio]-","Diuron-desdimethyl","Gly-Gly","1-Mercapto[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one",".alpha.-Guanidinoglutaric acid","Prostaglandin E3","2'-Hydroxy-3,4,4',5-tetramethoxychalcone","1,8-dinitropyrene","Calceolarioside A","Maltitol","Frangulin A","3-(2-Hydroxy-4-oxo-1(4H)-pyrimidinyl)propanoic acid","Mandelate","3-(6-(.beta.-D-Glucopyranosyloxy)-2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-yl)propanoic acid","L-Theanine","21-Carboxylic acid triamcinolone acetonide","Altenusin","4-Amino-5-(4-methoxybenzyl)-4H-1,2,4-triazol-3-yl hydrosulfide","2-hydroxyisocaproic acid","Corymbiferin","Beta-alanine","Met-Gln","1H-2-Benzopyran-7-butanoic acid, 6,8-dihydroxy-.alpha.,.gamma.-dimethoxy-3-methyl-1-oxo-, methyl ester","4-Methyl-2-oxovaleric acid","Phosphatidylcholine lyso 20:0","Uridine 5'-diphosphoglucuronic acid","Tafluprost (free acid)","Laminaritetraose","5,6-Difluoro-1H-indole-2-carboxylic acid","(2-Methyl-6,7-dihydro-1H-[1,4]dioxino[2,3-f]benzimidazol-1-yl)acetic acid","6-Amino-1-methyl-5-nitrosouracil","2-(6-Hydroxyhexyl)-3-methylidenebutanedioic acid","N-Acetylneuraminic acid","3-((1-(2-Carbamoylanilino)-1-oxopropan-2-yl)amino)-3-oxopropanoic acid","3-(4-Hydroxy-2,2-dimethyl-1-oxo-3,3a-dihydroimidazo[1,2-a]indol-4-yl)-2-(4-oxoquinazolin-3-yl)propanoic acid","Pantothenic acid","Gln-Pro","2-Propylglutaric acid","Eudesmin","3-O-Demethylsulochrin","(E)-5-[4-(Carboxymethyl)-4-methoxycarbonyl-3-methyl-6-methylidene-2-oxo-3a,5,7,7a-tetrahydro-3H-1-benzofuran-5-yl]-3-methylpent-2-enoic acid","Aniquinazoline B","Glyceraldehyde","4-[(4-Carboxybutanoyl)amino]benzoic acid","(-)-.alpha.-Kainic acid","Xanthurenic acid","D-Glucosamine 6-phosphate","N-Methyl-O-methyl-L-tyrosine","1-(2,4-Dihydroxy-5-nitrophenyl)ethanone","Phenylephrine","Glycine, 1,1'-(1,8-dioxo-1,8-octanediyl)bis[glycyl-","N-(1,1-Dimethyl-2-hydroxyethyl)-3-amino-2-hydroxypropanesulfonic acid","3-Hydroxy-3-(1-oxo-1,2,3,4-tetrahydro-2-naphthalenyl)-1,3-dihydro-2H-indol-2-one","Crustecdysone","5-(4-Methoxybenzylidene)thiobarbituric acid","Penicillamine disulfide","(9H-Purin-6-ylsulfanyl)acetonitrile","(2-oxo-2,3-dihydro-1h-indol-3-yl)acetic acid","7-Sulfanylheptanoic acid","N-.alpha.-(tert-Butoxycarbonyl)-L-glutamic acid","Prolylalanine","2-(4-Fluorobenzoyl)benzoic acid","Rutinose","Arg-Ser-Arg","3-Dehydroquinic acid","Ala-Ala","Swietenocoumarin b","Fa 18:2+2o","8-(2-hydroxy-1-methoxy-3-methylbut-3-enyl)-7-methoxychromen-2-one","6-[(4-Bromobenzoyl)amino]hexanoic acid","7S,8,17S-Trihydroxydocosa-4Z,9E,11E,13Z,15E,19Z-hexaenoic acid","3,5-Dimethyl-1H-pyrazole-4-carboxylic acid","Carbidopa","7-Chloro-5-(1H-pyrrol-2-yl)-1,3-dihydro-1,4-benzodiazepin-2-one","Phosphatidylethanolamine lyso 20:1","Asn-Val","[3,4,5-trihydroxy-6-(3,4,5-trihydroxybenzoyl)oxyoxan-2-yl]methyl 3,4,5-trihydroxybenzoate","Zaprinast","Ethyl 4-O-(4-carboxy-3-hydroxy-3-methylbutanoyl)-.beta.-D-glucopyranoside","Dantrolene","D-ornithine","Avocadyne","3,4-Dihydroxyacetophenone","10-Undecynoic acid","Isocitric acid","2-Amino-5-bromo-4-fluorobenzoic acid","4-Pyrimidinylmethanol","Glycerate","4,4'-(2-Methylpropane-1,1-diyl)diphenol","DL-3,4-Dihydroxyphenyl glycol","Leupeptin","3-hydroxy-c6-homoserine lactone","Tetrafluorosuccinic acid","7-Chloro-L-tryptophan","Estrone sulfate","4-Methyloxazole-5-carboxylic acid","Dihydroresveratrol","3-isochromanone","Fosamine","3-[(E)-Phenyldiazenyl]biphenyl-4-ol","2-[(1,6-Dihydro-6-oxo-2-pyrimidinyl)thio]acetic acid","Piceid","Linoleic acid","3-Hydroxy-3-methylglutaric acid","4-(4-(4-Hydroxy-3-methoxybenzyl)-3-(hydroxymethyl)tetrahydrofuran-2-yl)benzene-1,2-diol","5'-Hydroxymethyl-5'-desmethylmeloxicam","4,4,4-Trifluoro-1-(5-methylthiophen-2-yl)butane-1,3-dione","Dauricine","3-Hydroxybutyric acid","Candesartan","4-(1-Amino-2-carboxyethyl)benzoic acid","3,5-Di-tert-butyl-4-hydroxybenzoic acid","D-Quinovose","3-(Carboxymethyl)-1-.beta.-D-glucopyranosyl-1H-indole","NCGC00179941-01","Isoproterenol","6-hydroxymelatonin","2-[(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl]-3-ethyl-9,10-dimethoxy-5-oxido-2,3,4,6,7,11b-hexahydro-1h-benzo[a]quinolizin-5-ium","3-nitrobenzanthrone","(E)-2-Phenylethenesulfonic acid","2-[4-(4-Fluorophenyl)piperazin-1-yl]-6-methylpyrimidin-4(3H)-one","5-{2-[2-(1H-Tetraazol-5-yl)ethoxy]ethyl}-1H-tetraazole","N-Acetyl-L-tyrosine","{[3-Ethoxy-2-(ethoxycarbonyl)-3-oxo-1-propenyl]amino}acetic acid","4-[2-(4-Morpholinyl)ethoxy]benzoic acid","5'-phosphoribosyl-5-amino-4-imidazolecarboxamide (aicar)","Endothal","Columbianetin","Terephthalic acid","5-Chloro-2,4-dihydroxy-3-[(E)-4-hydroxy-3-(hydroxymethyl)-5-(1,2,6-trimethyl-3-oxocyclohexyl)pent-2-enyl]-6-methylbenzaldehyde","Ethyl 4-hydroxy-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxylate","Tetrahydroharman-3-carboxylic acid","6-Hydroxy-1,3-benzoxathiol-2-one",".alpha.,.beta.-glucooctanoic .gamma.-lactone","Spa-10c (sample)","Lysine","trans-Cinnamic acid",".alpha.,.alpha.,.alpha.-Trifluorothymidine","(17Z)-16-(Acetyloxy)-6-hydroxy-4,8,14-trimethyl-3,7-dioxo-18-norcholesta-17,24-dien-21-oic acid","4-(3-Formyl-2,5-dimethyl-1H-pyrrol-1-yl)benzoic acid","4-Amino-2-oxo-1,2-dihydropyrimidine-5-carboxylic acid","2-[3-[3-Hydroxy-4-(4-hydroxyphenyl)-2,5-dimethoxyphenyl]-5-oxo-2H-furan-2-yl]acetic acid","5-Cyclohexyl-3H-1,3,4-oxadiazole-2-thione","[1-(3,4-Dihydroxy-5-methoxyphenyl)-7-(3,4-dihydroxyphenyl)heptan-3-yl] acetate","Aceroside viii","Fosfluconazole","2-Dec-9-enylpentanedioic acid","4-Hydroxy-3-[(4-hydroxy-6-methyl-2-oxopyran-3-yl)methyl]-6-methylpyran-2-one","(2E,5E)-3,5,7-Trimethylocta-2,5-dienedioic acid","9,10-Dioxo-9,10-dihydro-1,5-anthracenedisulfonic acid","1-(Furan-3-yl)-4,6-dihydroxy-5,8a-dimethyl-4,6,7,8-tetrahydro-1H-isochromen-3-one","5-(p-Chlorobenzylidene)thiobarbituric acid","Lecocarpinolide H","Cyclohexylaminopropanesulfonic acid","(4E,6E)-2-(Hydroxymethyl)-3-(3-methoxy-3-oxopropyl)deca-4,6-dienoic acid","6-Isopropoxy-9-oxoxanthene-2-carboxylic acid","D-Galacturonic acid","5-Azacytidine","cis-4,10,13,16-Docosatetraenoic acid","5-Methoxy-3-indoleacetic acid","C10-las (sample)","Obatoclax","1-(10Z-Heptadecenoyl)-sn-glycero-3-phospho-(1'-rac-glycerol)","Phosphatidylcholine lyso 17","Phosphatidylcholine lyso 19","Perseitol","4-Fluoro-3-(methoxymethyl)-1-benzothiophene-2-carboxylic acid","3-O-Feruloylquinic acid","6-Hydroxy-2,2'-bipyridine-5-carbonitrile","2-Octanoyl-N-phenylhydrazinecarbothioamide","Umckalin","Gly-His-Lys","Carbazochrome sulfonate","Maleamic acid","2,5-Dichlorobenzene-1,4-diol","Atlantinone A","1-Naphthol .beta.-D-glucuronide","N-acetylputrescine","Alpha-d-glucose","Deschloronornidulin","Plantamajoside","1,4-cyclohexanedicarboxylic acid","3-[2-(4-Fluoroanilino)-2-oxoethoxy]benzoic acid","5-Methoxytryptophan","3-Piperidinecarboxamide, N-(4-chlorophenyl)-1-[3-(2-furanyl)benzoyl]-","N-(4-Hydroxyphenyl)-3,4,5-trimethoxybenzamide","6-(Acetyloxy)-2-naphthoic acid","2-Amino-3-methoxybenzoic acid","5,8-Dihydroxy-4-oxo-1,2,3,4-tetrahydronaphthalen-1-yl 6-O-(3,4,5-trihydroxybenzoyl)-.beta.-D-glucopyranoside","Ile-Val","(Z)-6,9,10-Trihydroxyoctadec-7-enoic acid","Nitrilotriacetic acid","6-Hydroxynicotinic acid","N-.alpha.-(tert-Butoxycarbonyl)-L-proline","(1,9,9b-trihydroxy-6,6,9a-trimethyl-3,5,5a,7,8,9-hexahydro-1h-benzo[e][2]benzofuran-5-yl) hexanoate","Calycin","Hydroquinone","1,4-butynediol","(1-Hydroxycyclohexyl)acetic acid","D-proline","Cyperanic acid","Thyrotropin releasing hormone","Acetic acid, 2-[4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy]-","3,4-Dihydroxy-DL-phenylalanine","N-(2-Phenoxyphenyl)methanesulfonamide","3-[(5-Oxo-2-pyrrolidinyl)carbonyl]-1,3-thiazolidine-4-carboxylic acid","Triptophenolide","cis-Aconitic acid","(5r)-5-[(1s,2s,3r,4r)-3-[(4e)-hex-4-enoyl]-6-[(2e,4e)-hexa-2,4-dienoyl]-5,7-dihydroxy-4,7-dimethyl-8-oxobicyclo[2.2.2]oct-5-en-2-yl]-4-hydroxy-3,5-dimethyl-2,5-dihydrofuran-2-one","Arg-His","5-Methyl-4-isoxazolecarboxylic acid","Ofloxacin","N-(Naphthalen-1-yl)benzamide","1-(4-Chlorophenyl)-2-(2,3-dihydroxy-3H-indol-3-yl)ethanone","2,4-Di-tert-amylphenol","D-Ribose","Flubromazepam","Henryoside","Sinomenine","Rubiadin","4-(4-Chlorobenzyl)-4H-1,2,4-triazol-3-yl hydrosulfide","1H-Indazole-3-carboxamide, N-1-naphthalenyl-1-pentyl-","2-[(4-Chlorobenzyl)sulfanyl]-4-pyrimidinol","Pimecrolimus","N-Acetyl-2-carboxybenzenesulfonamide","5-methoxyuridine","4-Hydroxyisophthalic acid","Zinniol","Probucol","2,5-dihydroxy-3,6-diphenyl-1,4-benzoquinone","Ser-Asp","(2r,3s,4s,5r,6s)-2-(hydroxymethyl)-6-[4-[(e)-3-hydroxyprop-1-enyl]phenoxy]oxane-3,4,5-triol","Gln-Gln","4-Phenyl-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl hydrosulfide","N-Phthaloylalanine","Ser-Asn","Gln-Gly","5-(Diaminomethylideneamino)-2-(3,4'-dihydroxy-4,4,7,8a-tetramethyl-6'-oxospiro[2,3,4a,5,6,7-hexahydro-1H-naphthalene-8,2'-3,8-dihydrofuro[2,3-e]isoindole]-7'-yl)pentanoic acid","2-(Benzoylamino)-5-phenyl-3-thiophenecarboxylic acid","2(1H)-Pyridinone, 3-[(2S,4S,5R)-5,6-dichloro-2,4-dimethyl-1-oxohexyl]-4-hydroxy-5,6-dimethoxy-","N-Acryloyl-DL-aspartic acid","Felodipine","Mercaptosuccinic acid","L-Alanyl-L-norleucine","2-[[4-(2,5-Dimethyl-1H-pyrrol-1-yl)phenyl]thio]acetic acid","6-Chloro-2-(4-methylphenyl)-4-quinolinecarboxylic acid","Arcyriaflavin A","4-Hydroxy-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione","Ethyl 6-oxo-2-phenyl-1,6-dihydro-5-pyrimidinecarboxylate","L-Hydroxyarginine","5-(3,4-dihydroxyphenyl)-6,7-dimethyl-5,6,7,8-tetrahydronaphthalene-2,3-diol","3-(2,6-Dichlorophenyl)-5-(propan-2-yl)-1,2-oxazole-4-carboxylic acid","2,4-dihydroxy-6-methyl-3-[(2e,4e)-3-methyl-5-[(1r,2r,6r)-1,2,6-trimethyl-3-oxocyclohexyl]penta-2,4-dienyl]benzaldehyde","2-(9-Decenyl)glutaconic acid","(E)-4-Hydroxy-4-[4-hydroxy-2-[(E)-6-hydroxyhept-1-enyl]cyclopentyl]but-2-enoic acid","4-{[(2E)-6,7-Dihydroxy-3,7-dimethyloct-2-en-1-yl]oxy}quinolin-2(1H)-one","11-Dehydrothromboxane B2","Eglumegad","Cassythicine","Fraxidin","Pyrrole-2-carboxylic acid","5,6,7-trimethoxycoumarin","(4-((1H-Imidazol-2-yl)methyl)piperidin-1-yl)(4'-fluoro-[1,1'-biphenyl]-4-yl)methanone","L-Alaninamide, N-[2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-","Methyl (2S,3Z,4S)-2-(.beta.-D-glucopyranosyloxy)-3-(2-hydroxyethylidene)-4-(2-(2-(4-hydroxyphenyl)ethoxy)-2-oxoethyl)-3,4-dihydro-2H-pyran-5-carboxylate","Ile-Gly-Ile","Neoechinulin B","Dl-3-aminoisobutyric acid","9-Hydroxynonanoic acid","N-(2-Phenylethyl)-9H-purin-6-amine","Secoisolariciresinol","Olopatadine","3-Methoxy[1]benzothieno[2,3-c]quinolin-6(5H)-one","Neohesperidose","Dopamine","3-(1H-Benzimidazol-2-yl)propanohydrazide","Methyl heptadecanoic acid","2-(1H-Benzimidazol-2-ylsulfanyl)-N,N-diethylethanamine","(z)-3-hydroxyhexadec-7-enoic acid (nmr)","3,5-dinitrosalicylate","Butalbital","trans-Glutaconic acid","Pantothenate","2-[(4-Fluoroanilino)carbonyl]benzoic acid","16,16-Dimethylprostaglandin A2","8-Ethoxy-5-quinolinesulfonic acid","p-Bromophenylacetic acid","Tyr-Ala","2-Amino-3-bromo-5-fluorobenzoic acid","[(3as,4s,5s,6e,10z,11ar)-6-formyl-5-hydroxy-10-(hydroxymethyl)-3-methylidene-2-oxo-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-4-yl] 2-methylprop-2-enoate","4-[5-(Hydroxymethyl)-8-methyl-3-oxabicyclo[3.3.1]non-7-en-2-yl]phenol","Rhein","2-Thiouracil","Atranorin","[(Ethoxycarbothioyl)sulfanyl]acetic acid","L-Kynurenine","5-(1H-Benzimidazol-2-ylsulfanyl)furan--2-carbaldehyde","N-acetylmuramic acid","6-Amino-5-bromo-3-pyridinesulfonic acid","Ferulate","2,3-Dioxoindoline-7-carboxylic acid","2-Mercaptoethanesulfonic acid","1,2-Di(1H-benzimidazol-2-yl)ethanol","Tyr-Asp","L-homocysteic acid","5-[(Aminocarbonyl)amino]pentanoic acid","(4-oxido-2,3,5,6,7,8-hexahydro-1h-pyrrolizin-4-ium-1-yl)methyl 2,3-dihydroxy-3-methylpentanoate","Rosmic acid","Citreohybridonol","2'-deoxyinosine-5'-triphosphate trisodium salt","3-Phenylbenzo[f]quinoline-1-carboxylic acid","6-Fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid","Vidofludimus","Adipic acid","Sulfanilate","1H-Spiro[benzo[4,5]imidazo[1,2-a][1,3,5]triazine-4,1'-cyclopentan]-2-amine","Acetylsyringic acid","Cyclanilide","4-thiouridine","2-hydroxy-4-(methylthio)butanoate","N-(9-Fluorenylmethoxycarbonyl)-L-leucine","2-Benzyl-3-phenylpropanoic acid","4-Allyl-5-(2-thienyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione","4-Hydroxypropranolol .beta.-D-glucuronide","Isoleucine","4-Formyl-2-hydroxybenzoic acid","L-Homocystine","2-(1-Pyrrolidinylcarbonyl)benzoic acid","Thiouric acid","Oxfendazole","Dikegulac acid","Canertinib","Met-Pro","Enalaprilat tert-butyl ester","Niflumic acid","Fludarabine","2,3-Quinoxalinedione, 1,4-dihydro-6,7-dinitro-","Doxycycline","2-[(4-Phenoxybenzoyl)amino]benzoic acid","Benzeneacetamide, N-[(1S)-2-[[(3S)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-","5-[(6-Methoxy-1H-benzimidazol-2-yl)sulfanyl]-2-furaldehyde","3-Hydroxy-2',5'-dichlorobiphenyl","Syringolin C","4-({Methyl[2-(methylamino)-2-oxoethyl]amino}sulfonyl)butanoic acid",".beta.-hydroxypropionic acid","Syringolin A","(1S)-1,5-Anhydro-1-(1,3,6-trihydroxy-5-methoxy-9-oxo-9H-xanthen-2-yl)-D-glucitol","N-Acetyl-L-phenylalanine","Caproic acid","Rabelomycin","6-Aminocaproic acid","2-(1H-Benzimidazol-2-ylamino)-6-methyl-4-pyrimidinol","Peucenin","His-Arg","4-Phenyl-2-sulfanyl-3,4-dihydro-5H-indeno[1,2-d]pyrimidin-5-one","3,5-Dichlorotyrosine","Raltitrexed","Fenhexamid","DL-.alpha.-Aminopimelic acid","Thr-Arg","2-(Naphthalen-1-yl)-1H-1,3-benzodiazole","4-(2-Benzoyl-4-chloroanilino)-4-oxobutanoic acid","Berberine","4-acetamidobutanoate","PyroGlu-Val","Isoroquefortine C","4-Imidazoleacrylic acid","Deoxyadenosine","Thr-Asp","Thr-Asn","6-(4-Methylbenzenesulfonamido)hexanoic acid","Ser-Ala","Zearalanone","2'-Chloro-2-hydroxy-5-methylbenzophenone","trans-Traumatic acid","1-o-trans-cinnamoyl-beta-d-glucopyranose","1-Dehydroperuvinine","5-Methyl-2-[(4-methyl-1-piperazinyl)carbonyl]-1H-indole","Asn-Gly-Asn","PC 34:2","N-(4-Methoxy-2-nitrophenyl)isonicotinamide","Ala-Ser","(2E,4E)-12-Hydroxy-13-(hydroxymethyl)-14-methoxy-3,5,7-trimethyl-14-oxotetradeca-2,4-dienoic acid","Ethyl 5-fluoro-3-methyl-1H-indole-2-carboxylate","2,3-Diphenyl-1H-indole-7-carboxylic acid","9-Hydroxycalabaxanthone","1,6-Bis-O-(4-hydroxycinnamoyl)glucose","(3,6,9-trimethylidene-2-oxo-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-8-yl) acetate","(2E,5R,6R,11S)-5,6,15-Trihydroxy-17-methoxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(14),2,15,17-tetraene-7,13-dione","3-Bromo-5-(2H-tetraazol-5-yl)pyridine","2-(2-Hydroxypropan-2-yl)-4-methoxy-6-(2-phenylethyl)-2,3-dihydro-1-benzofuran-7-carboxylic acid","3-Amino-1-propanesulfonic acid","3-Azetidinecarboxylic acid, 1-(4-fluorobenzoyl)-3-[[(6-methoxy-2-naphthalenyl)oxy]methyl]-","Teniposide","4-Ethoxy-6-fluoroquinoline-2-carboxylic acid","Salicylic acid","Benzamide, N-[2-(dimethylamino)ethyl]-N-methyl-4-[[[[4-[4-(4-morpholinyl)-7-(2,2,2-trifluoroethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]phenyl]amino]carbonyl]amino]-","Alanine","Methyl 3-hydroxy-4-nitrobenzoate","3-Fluoro-9H-carbazole","5-(p-Nitrobenzylidene)barbituric acid","Ile-Met","4-Oxododecanedioic acid","4-Cyclohexyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione","2-carboxybenzaldehyde","2-(4-Methoxyphenoxy)-5-nitrobenzoic acid","N-(Phenylacetyl)urea","7-Hydroxyprochlorperazine","5-(Phenylsulfonyl)-2-thiophenecarboxylic acid","[2-(1H-Tetraazol-5-yl)phenoxy]acetic acid","Acetyl-dl-leucine","Val-Thr","2-[(2-Ethylbutanoyl)amino]-4,5-dimethoxybenzoic acid","5-Chloro-1H-indazole-3-carboxylic acid","Lamalbide","D-(+)-Arabitol","Dibenzo[b,f][1,4]thiazepin-11(10H)-one",".beta.-D-Glucopyranoside, 1-methyl-1-(4-methyl-3-cyclohexen-1-yl)ethyl 6-O-(6-deoxy-.alpha.-L-mannopyranosyl)-","Mycophenolic acid phenolic .beta.-D-glucoside","Diclofop","Daphnin","N-[1-Oxo-3-(4-oxo-1,2,3-benzotriazin-3(4H)-yl)propyl]glycine","5-Formyl-2-hydroxybenzene-1-sulfonic acid","4-Methoxy-2,4-dioxobutanoic acid","2-Naphthalenesulfonamide, N-(4-aminobutyl)-5-chloro-","Heteropeucenin, methyl ether","(8.Xi.,9.Xi.,14.Xi.)-3-((6-Deoxy-.alpha.-L-mannopyranosyl)oxy)-1,5,14-trihydroxycard-20(22)-enolide","Swertiamarin","Val-Gly","3-Hydroxyphthalic anhydride","Pentalenolactone E","4H-Thiopyrano[4,3-d]pyrimidin-4-one, 3,5,7,8-tetrahydro-2-[4-(trifluoromethyl)phenyl]-","2-Fluoro-4-(methylsulfonyl)benzoic Acid","Pyruvaldehyde","Pentalenolactone O","6-Hydroxy-2-methylindole","5-Benzoyl-4-hydroxy-2-methoxybenzenesulfonic acid","3,5-Dimethyl-1H-pyrazole-4-carbaldehyde","(4Z)-2-(4-(Hexopyranosyloxy)phenyl)-4-(4-hydroxybenzylidene)-5-oxotetrahydrofuran-3-carboxylic acid","2-Butenedioic acid, 1-(1,3,5,5a,6,7,8,9,9a,9b-decahydro-9b-hydroxy-6,6,9a-trimethyl-1-oxonaphtho[1,2-c]furan-5-yl) ester","N-acetylasparagine","5-Methyl-2'-deoxycytidine","3-(2-Amino-4-methyl-6-oxo-1,6-dihydro-5-pyrimidinyl)propanoic acid","Ribose","Leu-Ser","Val-Gln","1-(2,4-Difluorophenyl)-5-oxo-3-pyrrolidinecarboxylic acid","Curcumin","Laurylsulfuric acid","(2,6,6-Trimethyl-4-oxocyclohex-2-en-1-yl)methyl .beta.-D-glucopyranoside","N-acetylglucosamine","cis-4-Hydroxycyclohexanecarboxylic acid","Perifosine","Dethiobiotin","Arecaidine","3-Hydroxystanozolol glucuronide","2-Phenyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-ol","1-(4-Chlorobenzoyl)proline","2,3-Dihydroxybenzoic acid","Picraquassioside A","3-(Ethoxycarbonyl)-4-methyl-1H-pyrrole-2-carboxylic acid","Tetraazolo[1,5-a]pyridine-8-carboxylic acid","Glycyl-L-4-hydroxyproline","Phosphatidylcholine lyso alkyl 16:0","Ramipril","2-Hydroxy-N-(4-methylphenyl)-5-nitrobenzamide","6-Bromo-2,3,4,9-tetrahydro-1H-carbazole","Ethylenediaminetetraacetic acid","Salicylic acid .beta.-D-O-glucuronide","rac-2-Despiperidyl-2-aminorepaglinide","Glu-Leu","cis-Melilotoside","4-[4-(Benzyloxy)anilino]-4-oxobutanoic acid","Parecoxib","2-Methylbenzoic acid","Mangostine","Plinabulin","3,3'-Disulfanediyldibenzoic acid","Resveratrol 4'-O-D-glucuronide","Dinaphtho[2,1-d:1,2-f][1,3,2]dioxaphosphepin-4-ol 4-oxide","Phenylglyoxylic acid","4-Hydroxy-3-[2-(1H-imidazol-5-yl)ethyl]-4,5,5-trimethyl-1,3-oxazolidin-2-one","Leu-Asn","3-(2-Hydroxyphenyl)propionic acid","Syringic acid","2-(1-Naphthyl)-4-quinolinecarboxylic acid","Mesaconic acid","alpha-Tocopherol (Vitamin E)","Methanone, (4-hydroxyphenyl)(1-pentyl-1H-indol-3-yl)-","Neochlorogenic acid","2-Hydroxybenzene-1,3-dicarboxylic acid","2-[[(guanidino) (imino)methyl]sulfanyl]ethanesulfonic acid","N-.delta.-BOC-L-Ornithine","Adipoyl-L-carnitine","4-(5,7-Dioxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)benzoic acid","2-(4-Cyclohexylphenyl)propanoic acid","4-Oxo-4-[3-(trifluoromethyl)anilino]butanoic acid","(2-{2-[(3-Chlorophenyl)amino]-2-oxoethoxy}phenyl)phosphonic acid","Kanamycin A","Ethyl sulfate","4-{2-[4-(Dimethylamino)phenyl]diazen-1-yl}benzene-1-sulfonic acid","6,8-Difluoro-7-hydroxy-4-methylcumarin","N-(6-Amino-1-butyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-N-methylbenzenesulfonamide","Ginkgolide a","2-Chloro-N-(2-fluoro-5-nitrophenyl)acetamide","7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine","4-Propylphenol","4-sec-Butylphenol","Isorosmanol","(Diethylamino)(oxo)acetic acid","Val-Phe","Propanoic acid, 2-[[4-[2-[[(cyclohexylamino)carbonyl](4-cyclohexylbutyl)amino]ethyl]phenyl]thio]-2-methyl-","3-Phosphonoalanine","Ser-Ser","4,4-Dimethyl-L-glutamic acid","Pseudouridine","6-Nitro-1,3-benzothiazol-2(3H)-one","2-Methylglutaric acid","2-(2-Ethoxy-2-oxo-1-phenylethyl)-1,3-thiazolidine-4-carboxylic acid","Phthalazinone pyrazole","2-(Propane-1-sulfonamido)benzoic acid","Nitrotyrosine","Pelitinib","N-2-Hydroxyethylpiperazine-N-3-propanesulfonic acid","Chelidonic acid","9-(1,3-Dihydroxy-3-methylbutyl)-6-hydroxy-4-methoxy-3a,12a-dihydro-5H-furo[3',2':4,5]furo[3,2-b]xanthen-5-one","2-Isonicotinoyl-N-methylhydrazinecarbothioamide","Isovaleric acid","1H-Indole-3-propanoic acid","1-(tert-Butoxycarbonyl)-2,5-dihydro-1H-pyrrole-2-carboxylic acid","p-Hydroxyphenyllactic acid","N-Benzoyl-DL-leucine","Ibuprofen .beta.-D-glucuronide","Glycyrrhizic acid","3-amino-3-(4-hydroxyphenyl)propionate","3-Ethoxy-2-hydroxy-5-nitrobenzaldehyde","5-[Bis(2-chloroethyl)amino]uracil","Verruculotoxin","4-acetoxyphenol","Dasatinib","11-Dodecenamide, 12,12-dibromo-N-(methylsulfonyl)-","Methyl 3,4,5-trimethoxycinnamate","Arachidonic acid (peroxide free)","Amifostine","p-Acetamidophenyl .beta.-D-glucuronide","Isomajdine","2-Hydroxy-3-(2-hydroxyethyl)-4(3H)-quinazolinone","Methyl 2-[(2,3-dihydroxybenzoyl)amino]-3-hydroxypropanoate","2-(3-Carboxypropionylamino)-4-methylsulfanylbutyric acid","5-((1E,3E)-Hepta-1,3-dien-1-yl)-1,2,3-trihydroxycyclopentanecarboxylic acid","Monomethylsulochrin","3-Sulfobenzoic acid","6-Bromo-3-methoxy-1H-indazole","3-[4-(4-Hydroxy-2-quinazolinyl)benzyl]-2,4-imidazolidinedione","Glu-Phe","D-Gluconic acid","1H-Pyrrole-3-propanoic acid, 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-","4'-Fluoro[1,1'-biphenyl]-4-carboxylic acid","Mycosporine serinol","Isoxanthopterin","1-(4-Methylbenzyl)-5-oxo-3-pyrrolidinecarboxylic acid","Reserpic acid","2-[7-Acetyloxy-5-chloro-3-[(1E,3E)-3,5-dimethylhepta-1,3-dienyl]-7-methyl-6,8-dioxoisoquinolin-2-yl]-5-(diaminomethylideneamino)pentanoic acid","1H-Indole-3-carboxylic acid, 1-(cyclohexylmethyl)-","2-Acetamidophenol","2-[3-(2H-1,2,3-Benzotriazol-2-yl)-4-hydroxyphenyl]ethyl 2-methylacrylate","1-[4-Methyl-6-(trifluoromethyl)pyrimidin-2-yl]piperidine-3-carboxylic acid","5,7-Dihydroxy-4-methylcoumarin","3-(N-Maleimidopropionyl)biocytin","2-(5-Methyl-2-furyl)-1H-benzimidazole","Suberylglycine","Benzeneacetamide, N-[(1S)-2-[[(7S)-6,7-dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-","4-(4-Phenyl-5-sulfanyl-4H-1,2,4-triazol-3-yl)phenol","4-Quinazolinamine, N-(3-bromophenyl)-6,7-dimethoxy-","Cycloheximide","Homogentisic acid","4-(4-Fluorophenyl)-2,3-dihydro-1,3-thiazol-2-one","Acetylcarnitine","2-amino-3-[hydroxy-[2-hydroxy-3-[octadec-9-enoyl]oxypropoxy]phosphoryl]oxypropanoic acid","1-Hydroxy-N-(3-nitrophenyl)-2-naphthamide","Thelephoric acid","D-Leucyl-L-arginine","L-Rhamnose","Phe-Pro","12(13)-Epoxy-9Z-octadecenoic acid","2-[(Phenylsulfonyl)amino]-5-propylbenzoic acid","3,4-Dihydroxy-L-phenylalanine","6-(4-Nitro-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)hexanoic acid","Mannose","5-(Diphenylphosphinyl)pentanoic acid","Glucose","3-[(1E,3E)-Hepta-1,3-dienyl]pentanedioic acid","Zanamivir","N-(2,5-Dichlorophenyl)-3-hydroxy-2-naphthamide","4-Hydroxy-3-[1-(5-hydroxy-2,6,6-trimethyltetrahydro-2H-pyran-2-yl)ethyl]-2(1H)-quinolinone","Leu-Ala","2-(1H-1,2,4-Triazol-5-yl)-1H-isoindole-1,3(2H)-dione","4-Acetyloxy-6-hydroxy-2-(2-hydroxypropan-2-yl)-4a,6-dimethyl-3,4,5,7,8,8a-hexahydro-2H-chromene-5-carboxylic acid","(+)-Fluprostenol","Carmoxirole","10-Hydroxy-2-decenoic acid","N-{3-[(Methylsulfonyl)amino]phenyl}methanesulfonamide","DL-Indole-3-lactic acid","Thr-Thr","3-hydroxybenzo(a)pyrene","Gly-Gly-Val","Auranthine","Amoxicillin","2-Amino-N-benzyl-3-(1H-indol-3-yl)propanamide","5-Acetyl-2-thiophenecarboxylic acid","Ivacaftor","5-Tetradecynoic acid","1-(4-Chlorophenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione","Val-Tyr","Valsartan","Thr-Gln","1-(1,2-Dihexanoylphosphatidyl)inositol-5-phosphate","(r)-2-hydroxystearic acid","Arg-Glu","3a,6-Dihydroxy-9-(3-hydroxy-3-methylbutyl)-4-methoxy-3a,12a-dihydro-5H-furo[3',2':4,5]furo[3,2-b]xanthen-5-one","1-Palmitoyl-2-oleoyl-phosphatidylglycerol","2-Propyl-4-pentenoic acid","Arg-Gln","1H-Indole-1-butanoic acid, 3-(1-naphthalenylcarbonyl)-","Olmesartan medoxomil","3-(Ethoxycarbonyl)-5-nitrobenzoic acid","Terbuthylazine-tp cscd648241 (lm6)","Altamisic acid","Dye X-6012-14H","1-Isopropyl-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid","Alpha-ketoisovaleric acid","[1,1'-Biphenyl]-3,3',4,4'-tetracarboxylic acid","N-(1H-Benzimidazol-2-yl)-3-nitrobenzamide","[8,8-dimethyl-10-(3-methylbut-2-enoyloxy)-2-oxo-9,10-dihydropyrano[2,3-f]chromen-9-yl] 3-methylbutanoate","Diethyl 1H-pyrazole-3,5-dicarboxylate","Gliotoxin","Paprotrain","His-Glu","N2-Isobutyryl-2'-deoxyguanosine","3-(4-Fluorophenyl)-1H-indole","Pimelic acid","D-Turanose","Valine","N-acetylgalactosamine","3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid","Mitomycin c","Thr-Glu","3-(6-Oxopyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-7(6H)-yl)propanoic acid","Benz[a]anthracen-1-ol, 8-methoxy-3-methyl-","6-Methyl-2-thiouracil","Phosphatidylethanolamine lyso alkenyl 16","Phe(Benzoyl)-Leu-Arg","4-(Hydroxymethyl)benzenesulfonic acid","4-Cyanotetrahydropyran-4-carboxylic acid","Aigialomycin D","(2-Phenyl-1,3-benzothiazol-5-yl)acetic acid","3-Methoxy-4-hydroxyphenylglycol sulfate","Nicotinamide ribotide","Phosphatidylethanolamine lyso alkenyl 18","(R)-(-)-2-Oxothiazolidine-4-carboxylic acid","7-[Anilino(phenyl)methyl]-8-quinolinol","Itaconic acid","Acetaminophen sulfate","16.alpha.-Hydroxyestrone","2.alpha.-Mannobiose","--","4-acetylbutyrate","N2-Trifluoroacetyl-L-glutamine","1-(tert-Butoxycarbonyl)-3-piperidinecarboxylic acid","Phosphatidylinositol lyso 16","Pro-Ser","Phosphatidylinositol lyso 18","Enrofloxacin","N-Acetyl-L-aspartic acid","4-Hydroxy-3-methoxy-2-nitrobenzaldehyde","Octyl .alpha.-ketoglutarate","Di(2-thienyl)acetic acid","L-Ala-Gly-Gly-Gly","(5e)-4,9-dihydroxy-6-methyl-3,10-dimethylidene-4,7,8,9,11,11a-hexahydro-3ah-cyclodeca[b]furan-2-one","5,6-Isopropylidene-L-ascorbic acid","Suxibuzone","N-(1,3-Benzodioxol-5-yl)-4-methylbenzenesulfonamide","Gly-Lys","Cholesterol 3-sulfate","2-Keto-L-gulonic acid","Iodosulfuron-methyl","3-[3-(4-Fluorophenyl)-1H-pyrazol-5-yl]-N-methyl-1-propanamine","N-Ethyl-4-hydroxy-N-phenylbenzenesulfonamide","Docynicaside A","Leu-Arg","Glutathione, oxidized","1h-2-benzoxacyclotetradecin-1-one, 3,4,5,6,7,8,9,10-octahydro-14,16-dihydroxy-3-methyl-7-oxo-, (e)-","4-[(Methylsulfonyl)amino]benzenesulfonamide","4-Fluoro-3-(morpholin-4-ylsulfonyl)benzoic acid","Dodecylbenzenesulfonic acid","Quinate","2-Dec-9-enyl-3-hydroxypentanedioic acid","2-((4-Methylpiperazin-1-yl)methyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-ol","Glu-Pro","1H-Indole-1-pentanoic acid, 3-[2-(2-chlorophenyl)acetyl]-","N-L-.gamma.-Glutamyl-L-leucine","5-Acetylamino-6-amino-3-methyluracil","Difenacoum","(S)-2-Ureidopentanedioic acid","5-Oxo-1-[3-(trifluoromethyl)phenyl]-3-pyrrolidinecarboxylic acid","6-(6-Aminohexanamido)hexanoic acid","Ile-Asp","Allantoin","Ile-Asn","Ala-Val","4,5-Dimethoxy-2,3-dihydro-1H-isoindole-1,3-dione","4-(3-Acetyl-2,6-dihydroxyphenyl)-4-(hexopyranosyloxy)-2-methoxybutanoic acid","Formylanthranilic acid","7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide","5-(2,5-Dioxooxolan-3-yl)-7-methyl-1,3,3a,4,5,7a-hexahydro-2-benzofuran-1,3-dione","9-(2,3-Dihydroxypropoxy)-9-oxononanoic acid","1,7-bis(3,4-dihydroxyphenyl)heptan-3-yl acetate","6-Fluoro-2,3,4,9-tetrahydro-1H-carbazole","N'-[(1E)-(5-Chloro-2-hydroxyphenyl)methylene]-2-morpholin-4-ylacetohydrazide","1,11-Undecanedicarboxylic acid","Enalapril","Benzyl 6-nitro-1H-benzimidazol-2-yl sulfide","Atropine","L-Saccharopine","5-Hydroxytryptophan",".gamma.-Glu-Cys","1,2,3,6-Tetrahydropyridine-4-carboxylic acid","DL-Malic acid","Arctigenin","4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid","Methyl (19.alpha.,20.alpha.)-11-methoxy-19-methyl-16,17-didehydrooxayohimban-16-carboxylate","Gly-Leu",".gamma.-L-Glutamyl-L-alanine","{3-[3-(3-Fluorophenyl)-1H-pyrazol-5-yl]propyl}(methyl)amine","4-Methoxy-2H-isoquinolin-1-one","10,12-Dihydroxy-5-methyl-2,3,4,5-tetrahydro-1aH-oxireno[h][3]benzoxacyclododecine-7,13(8H,13aH)-dione","5a-Hydroxy-4-(4-oxoquinazolin-3(4H)-yl)-2-(propan-2-yl)-4,5,5a,9c-tetrahydro-3H-2a,9b-diazacyclopenta[jk]fluorene-1,3(2H)-dione","Carnequinazoline A","2-naphthalenesulfonic acid","Bromacil","5-Chloro-3-[(1E,3E)-3,5-dimethylhepta-1,3-dienyl]-7,8a-dihydroxy-1-methoxy-7-methyl-1H-isochromene-6,8-dione","2,4-Quinazolinediamine, N2,N4-bis(phenylmethyl)-","5-(4-Methyl-2-nitrophenyl)-2-furoic acid","3-hydroxyproline","Cyclo(phenylalanyltryptophyl)","N-.alpha.-Acetyl-L-ornithine","Ethyl 6,7,8-trifluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylate","2-{[(Isopropylamino)sulfonyl]amino}benzoic acid","Val-His","Coatline B","Ethyl glucuronide","3-hydroxy-5,5,8a-trimethyl-3,4,4a,6,7,8-hexahydronaphthalene-2-carboxylic acid","7-(Trifluoromethyl)-1H-indole-2,3-dione","Bis(2-hydroxy-1-naphthyl)disulfide","Daunorubicin","Lariciresinol","L-Gulono-1,4-lactone","Pentadecanoic acid","2,6-Bis(2-benzimidazolyl)pyridine","2-(1H-Pyrrol-1-yl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid","Dihydro-4,4-dimethyl-2,3-furandione","1,3-Dimethylbarbituric acid","3-(2,3-Dihydro-1,4-benzodioxin-6-ylsulfonyl)propanoic acid","3-O-Methylgallic acid","Indolelactic acid","3'-Methyl[1,1'-biphenyl]-3-carboxylic acid","(2R,3R,4S,5S,6R)-2-Octoxy-6-[[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxymethyl]oxane-3,4,5-triol","N-Palmitoyltryptamine","Maltotetraose","N-Acetyl-DL-valine","Xanthotoxol","1-methylguanosine","6-Chloroquinoxalin-2-ol","2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4-dihydro-3-hydroxy-2,2-dimethyl-4-[(phenylmethyl)amino]-, (3R,4R)-rel-","pGlu-Glu-Pro-amide","Jacaglabroside b","5-Chloro-3-methyl-1-phenyl-1H-pyrazole-4-carboxylic acid","2-deoxyglucose 6-phosphate","4-Isoxazolepropanoic acid, .alpha.-amino-2,3-dihydro-5-methyl-3-oxo-","8Z,14Z-Eicosadienoic acid","2-Hydroxy-4-phenylindeno[1,2-d][1,3]thiazin-5(4H)-one","2-(3-Nitrophenyl)-4-quinolinecarboxylic acid","1,4-Bis(4-morpholinylmethyl)-2,3-naphthalenediol","Isopentenyl pyrophosphate","N-Acetyl-L-tyrosine ethyl ester","(10-Methyl-10H-phenothiazin-2-yl)acetic acid","Gallic acid","1,3-Dicaffeoylquinic acid","3-(3-Hydroxyphenyl)propanoic acid","2-Benzyl-4-(octahydro-2H-isoindol-2-yl)-4-oxobutanoic acid","(6-Methyl-3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)acetic acid","3-Furancarboxylic acid, tetrahydro-4-methylene-2-octyl-5-oxo-, (2R,3S)-","Lestaurtinib","Ginnalin B","Myristic acid","3-Methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one","9,10-dihydro-4,5,7-trihydroxy-9,10-dioxo-2-anthroic acid","4,4'-Diamino[1,1'-biphenyl]-2,2'-disulfonic acid","Bergaptol","Indomethacin","Humulone","5,5,5-Trifluoroleucine","10-Formyl-7,8-dihydrofolic acid","4'-Hydroxydiclofenac","Nevirapine","4-Fluoro-2-(methylthio)benzoic acid","Saluamine","Butanoic acid, 3-methyl-, 2-hydroxy-1-[hydroxy(7-methoxy-2-oxo-2H-1-benzopyran-6-yl)methyl]-2-methylpropyl ester","2-Chloro-1-(5-chloro-2-methyl-1H-indol-3-yl)ethanone","1,3,4,5-Tetrahydrothiopyrano[4,3-b]indole-8-carboxylic acid","Resveratrol","Flumequine","3-(4-Hydroxyphenyl)-3-oxopropanoic acid","scyllo-Inositol","6-Chloro-1H-indazole-3-carbonitrile","Nateglinide","3-hydroxy-c4-homoserine lactone","2-(3-Hexyl-4-methyl-2,5-dioxopyrrol-1-yl)-3-hydroxypropanoic acid","(2,6-Dihydroxy-4-methoxyphenyl)(4-hydroxy-2-methoxy-6-methylphenyl)methanone","N,N'-Diacetylcystine","5-trans-Prostaglandin D2","Gln-Lys","2-(Diphenylphosphoryl)-1,4-benzenediol","3-[N,N-Bis(2-hydroxyethyl)amino]-2-hydroxypropanesulfonic acid","N-Acetylglucosaminylasparagine","4-Aminosalicylic acid","Nicotinuric acid","Gly-Phe","2-(4-tert-Butylbenzoyl)benzoic acid","(E)-3,10-Dihydroxy-4,9-dimethyldodec-6-enedioic acid","1-[(3,5-Dimethyl-1,2-oxazol-4-yl)sulfonyl]piperidine-4-carboxylic acid","(R)-Prunasin","Purine","Isocalolongic acid","Lactupicrin","Thiophanic acid","Didanosine","1,3-Dihydroxy-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one","5-Bromo-3-fluoro-2-hydroxybenzoic acid","3-[(4-Fluorobenzoyl)amino]benzoic acid","4-hydroxymandelate","Dihydroxyacetone","Gartanin","Cysteine-s-sulfate","10phic10spc","6-Methyl-3-phenylpyrimido[5,4-e][1,2,4]triazine-5,7(6H,8H)-dione","4-Fluoro-3-methanesulfonylbenzoic acid","4-(Cyclohexyloxy)-4-oxobutanoic acid","2-[(E)-2-(4-Hydroxyphenyl)ethenyl]quinolin-8-ol","N-(4-Phenoxyphenyl)-2-pyrazinecarboxamide","Melibiose","Rutilantinone","Ethylmalonic acid","Methotrexate","5'-(N-Ethylcarboxamido)adenosine","1-(Morpholin-4-ylsulfonyl)piperidine-4-carboxylic acid","5-Bromo-4-chloro-2-hydroxybenzoic acid","3-Hydroxybenzaldehyde","Geniposidic acid","3,2'-Dihydroxy-4,4',6'-trimethoxychalcone","Nonanoic acid","L-Glutarylcarnitine","1-(4-Hydroxyphenyl)-2-phenyl-1-butanone","N-(1-Methyl-3-phenylpropyl)-1H-indole-6-carboxamide","2-Amino-4-chloro-6-nitrophenol","Homocitrate","6-(Difluoromethoxy)-1H-benzimidazole-2-thiol","N-Acetyl-L-cysteine","Ile-Ala","3-Chloro-2-hydroxy-5-(trifluoromethyl)pyridine","2-(2-Naphthyl)-1H-indole","(3S)-4-[(tert-Butoxy)carbonyl]morpholine-3-carboxylic acid","Succinic acid N,N-dimethylhydrazide","2-{[(4-Fluorophenyl)amino]methyl}phenol","Picolinic acid","3,4-(Methylenedioxy)cinnamic acid","Benzoic acid, 3-[[(3-carboxycyclohexyl)amino]carbonyl]-4-[3-[4-(4-phenoxybutoxy)phenyl]propoxy]-","6-(3,5-Dimethyl-1H-pyrazol-1-yl)-3(2H)-pyridazinone","6,7-Dihydroxycoumarin-4-acetic acid","5,7-Difluoro-1H-indole-2-carboxylic acid","5-Amino-2-(3-hexyl-4-methyl-2,5-dioxopyrrol-1-yl)-5-oxopentanoic acid","Equisetin","3-Amino-2-hydroxy-5-sulfobenzoic acid","(7r,8r)-7,8-dihydroxy-3,5,7-trimethyl-8h-isochromen-6-one","N-[3-([1,1'-Biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl]-N-methylglycine","Fraxin","Picloram","Deoxyguanosine","5-(4-Fluorophenyl)-1,3-oxazole-2(3H)-thione","D-2-aminobutyrate","Lipoamide","2-Pentenoic acid, 5-(4-chlorophenyl)-3-phenyl-, (2Z)-","Geranyl pyrophosphate","3-methylthiopropionate","Bropirimine","Olivetolcarboxylic acid","5-Acetylamino-6-formylamino-3-methyluracil","(3-Amino-6-hydroxy-4-methylthieno[2,3-b]pyridin-2-yl)(phenyl)methanone","5,5'-Methylenebis(2-hydroxy-3-methylbenzoic acid)","2,4-dinitrotoluene","Platyphyllonol","N-Tigloylglycine","2-Cyano-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide","3-Hydroxy-5-methoxy-2,2-dimethyl-7-(2-phenylethyl)-3,4-dihydrochromene-8-carboxylic acid","2-[(2,6-Dimethylanilino)carbonyl]benzoic acid","Sudca - sulfoursodeoxycholic acid","11b,13-Dihydrolactucopicrin","1H-Benzimidazol-2-yl 4-methylbenzyl sulfide","Inositol","Gerberinside","Androsterone sulfate","Tetrangomycin","Icos-19-ene-1,2,4-triol","N-[5-(2,5-Dioxopyrrolidin-1-yl)pentyl]-N-hydroxyacetamide","Boc-(R)-.alpha.-(4-bromobenzyl)proline","(2,4-Difluorophenoxy)acetic acid","3-Oxabicyclo[3.3.1]non-6-ene-1-methanol, 4-(4-hydroxyphenyl)-6,8,9-trimethyl-","2,6-Diaminopimelic acid","4-Fluoro-2-[(methylsulfonyl)amino]benzoic acid","2-[4-(1-Methyl-1-phenylethyl)phenoxy]propanoic acid","Leonurine","Lipoic acid reduced","Methoxytyrosine","[(Aminocarbonyl)(methyl)amino]acetic acid","Difucol hexamethyl ether","Gly-Gly-Ala","Haematommic acid","Butanoic acid","Butaprost (free acid)","5-Phenyl-1H-tetrazole","4,6-Dihydrothieno[3,4-b]thiophene-2-carboxylic acid","Hexose + c11h12o4","5-Nitro-2-(2-pyridinyl)-1H-benzimidazole","2-[1,1'-Biphenyl]-4-yl-4-quinolinecarboxylic acid","Tridecanoic acid (Tridecylic acid)","Gly-Tyr","2-tert-Butylphenol","L-Carnosine","1-Piperazinecarboxamide, 4-(3-chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-","L-2-Hydroxyglutaric acid","5-Methyl-2-[(phenylsulfonyl)amino]benzoic acid","(3,4-Dihydroxyphenyl)ethanol","1,1-Dioxo-[1,2]thiazolo[5,4-c]pyridin-3-one","2-Anthracenesulfonic acid","Albizziin","Nefiracetam","N-(3-Chloro-4-fluorophenyl)-4-quinazolinamine","DL-serine",".alpha.-D-Xylopyranose","N-Methyl-L-glutamic acid","2',3'-Dideoxycytidine","N6-(3-Chlorophenyl)-7H-purine-2,6-diamine","5-Hydroxy-7-(hydroxymethyl)-2-methyl-2-(5-oxooxolan-2-yl)-3H-chromen-4-one","Imazethapyr","5-(4-Fluoro-3-nitrophenyl)-1H-tetraazole","6.beta.-Naltrexol","Salazinic acid","Synephrine","Deoxycholic acid","5-[2-(4-Chlorophenyl)hydrazin-1-ylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione","N-acetylhistidine","Ethyl 7-hydroxy-2-oxo-2H-chromene-3-carboxylate","Cer[ns] d33:1","S-Lactoylglutathione","Dinoseb","N-Isobutyl-3-nitrobenzenesulfonamide","(5,6-Diphenylfuro[2,3-d]pyrimidin-4-yl)glycine","[8-[2-(3-methylbutanoyloxy)propan-2-yl]-2-oxo-8,9-dihydrofuro[2,3-h]chromen-9-yl] 3-methylbutanoate","4-[4-(2-Butoxyethoxy)-5-methyl-2-thiazolyl]-2-fluorobenzoic acid","Phenylpyruvate","(2E)-4-Hydroxynon-2-enoic acid","Ser-Thr","2-Amino-6-sulfanyl-3,5-pyridinedicarbonitrile","1H-Indole-3-carboxamide, 1-(5-fluoropentyl)-N-1-naphthalenyl-","Phloroacetophenone","Lonchocarpin","(-)-Syringaresinol-4-O-.beta.-D-glucopyranoside","Kenpaullone","Methyl 4-[(phenylsulfonyl)amino]benzoate","3-(5,7-Dimethoxy-4-oxochromen-2-yl)propanoic acid","Valdecoxib","Hydroxyferulic acid","Imazapyr","Capric acid","6-[3-[(3,4-dimethoxyphenyl)methyl]-4-methoxy-2-(methoxymethyl)butyl]-4-methoxy-1,3-benzodioxole","Methyl 2-[[4-hydroxy-3-(2-methylbut-3-en-2-yl)-5-(3-methylbut-2-enyl)phenyl]methyl]-3-(4-hydroxyphenyl)-4-methoxy-5-oxofuran-2-carboxylate","1H-Indole-1-acetic acid, 5-fluoro-2-methyl-3-(2-quinolinylmethyl)-","2-(1,1'-Biphenyl-4-ylcarbonyl)benzoic acid","Benzoic acid, 2,4-dimethoxy-6-methyl-, 4-carboxy-3-methoxy-5-methylphenyl ester","Sulfisomidin","(2S)-2-[[(1S)-1-Carboxy-3-methylbutyl]carbamoylamino]glutaric acid","Benzyl succinate","2,6-Bis(4-hydroxy-3-methoxybenzylidene)cyclohexanone","3',5'-cyclic damp","3,4-Dihydroxymandelic acid","Taurosteine","1-[4-Hydroxy-3-(3-methylbut-2-enyl)phenyl]ethanone","Silybin","4-Methyl-N-(2-nitrophenyl)benzenesulfonamide","Ser-Gly","Glutathione","3-(Difluoromethyl)-1H-pyrazol-5-amine","(1,1-Dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)acetic acid","Hydroferulic acid","Cyclopenta[b]pyran-5-octanoic acid, octahydro-.epsilon.,2,6-trioxo-, (4aR,5R,7aS)-","4-hydroxymandelonitrile","2-(1,2-Dihydroxy-2-phenylethyl)-3-hydroxy-2,3-dihydropyran-6-one","Aminoadipate","Carbetamide","(2S)-3-(1-Benzyl-1H-imidazol-4-yl)-2-{[(tert-butoxy)carbonyl]amino}propanoic acid","2-(Formylamino)benzoic acid","1-Pyrrolidineheptanoic acid, 2-[(1E,3S,4S)-3-hydroxy-4-methyl-1-nonen-6-yn-1-yl]-5-oxo-, (2R)-","Pro-Glu","Kainic acid","3,4,2',4',6'-Pentahydroxychalcone","Psychotrine","3-Methylpyrrole-2,4-dicarboxylic Acid","2-[4-Chloro-5-cyclopropyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]propanoic acid","(2r,3s,4s,5r,6r)-2-[[(2s,3r,4r)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxymethyl]-6-[4-(4-hydroxyphenyl)butan-2-yloxy]oxane-3,4,5-triol","Cinromide","Shikimic acid","2-Furanpropanoic acid, 3-carboxy-4-methyl-5-propyl-","3-methyl-2-oxopentanoate","3-(Benzoyloxy)-2-hydroxypropyl .beta.-D-glucopyranosiduronic acid","Saccharin","Thr-Met","Pipemidic acid","3-(5,5-Dimethyl-5,6-dihydro[1,2,4]triazolo[3,4-a]isoquinolin-3-yl)phenol","Gly-Phe-Arg","Vanillic acid","Succinic semialdehyde","Acetoacetic acid","Phe-Gly","1,4-Piperazinediethanesulfonic acid","Phe-Glu","Xanthyletin","Marticin","Mupirocin","3-tert-Butyl-4-hydroxyanisole","2-[(3,5-Difluorophenyl)formamido]acetic acid","3,3,3-Trifluoroalanine","2,3',4,6-tetrahydroxybenzophenone","3-Bromo-5-phenylsalicylic acid","Desethyleneciprofloxacin","Octanoic acid, 4-[(1-oxo-7-phenylheptyl)amino]-, (4R)-","4,5-Dimethyl-1,3-oxazole-2-thiol","4-[(e)-3-[1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxoprop-1-enyl]-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-3-carboxylic acid","(S)-3,5-Dihydroxyphenylglycine","Valeramide","Phe-Thr","2-Hydroxyibuprofen","Gln-Asp","6-Fluoro-3-methyl-1-benzothiophene-2-carboxylic acid","5-ethyl-2'-deoxyuridine","6,6'-Dihydroxy-5,5'-dimethoxybiphenyl-3,3'-dicarboxylic acid","Thiopental","Vincosamide","Diethyl 2,4-dimethylpyrrole-3,5-dicarboxylate","2-Oxohexanedioic acid","5-(Trifluoromethoxy)-1H-indole-2,3-dione","5-hydroxylysine","Uric acid","4-Oxo-4-{[(4-phenyltetrahydro-2H-pyran-4-yl)methyl]amino}butanoic acid","Philanthotoxin 74","Cilostamide","[8]-Shogaol","17-Phenoxytrinorprostaglandin F2.alpha.","2-Oxopentanedioic acid","Matairesinol","Methyl 2-[(4ar,5r,6r,7s,8ar)-8a-ethenyl-5,7-dihydroxy-4-methylidene-3-oxo-1,4a,5,6,7,8-hexahydroisochromen-6-yl]prop-2-enoate","Benazepril","Arg-Asn","3-Carboxy-6,8-difluoro-7-hydroxycoumarin succinimidyl ester","DL-threonine",".alpha.-Hydroxybutyric acid","Trp-Glu","Metameconine","2-[(2-Fluorobenzoyl)amino]-4-phenyl-3-thiophenecarboxylic acid","Methylsuccinic acid","Ala-Leu","Antibiotic WS 5995-C","Tetradecanedioic acid","Aripiprazole","2-[(2,3-Dichlorophenyl)amino]benzoic acid","Hydroxysebacic acid","6-Benzyloxycarbonylaminohexanoic acid","Erythritol","N-(3-Methylphenyl)-N'-(4-pyridinyl)urea","D-tryptophan","2-Amino-1H-quinazolin-4-one","(E)-5-Hydroxyundec-2-enoic acid","Proguanil","1,3-Dimethyl-1H-pyrazol-5-ol","(2E)-2-(Propan-2-yl)but-2-enedioic acid","1H-Pyrrole-2,5-dicarboxylic acid","2-Hydroxy-2',4',6'-trimethoxychalcone","L-3-Aminoisobutyric acid","Natamycin","1-Stearoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine","3-((3aS,6S,8aR)-8-Hydroxy-6,8-dimethyl-3-methylidene-2-oxooctahydro-2H-cyclohepta[b]furan-7-yl)propanoic acid","4,5-Dihydroxybenzene-1,2-dicarboxylic acid","Valeric acid","1-{2-[(2-Amino-6-hydroxy-9H-purin-9-yl)methoxy]ethoxy}-3-methyl-1-oxo-2-butanamine","1-(3,4,5-Trimethoxyphenyl)-1,2,3,4-tetrahydro-6,7-isoquinolinediol","Pumiloside","N-(4-Chlorobenzoyl)tryptophan","N2-(tert-Butoxycarbonyl)-N6-(trifluoroacetyl)lysine","B-Ala-lys","2-[(7a-Hydroxy-3-oxo-5-propan-2-yl-1,3a,4,5,6,7-hexahydro-2-benzofuran-4-yl)-hydroxymethyl]prop-2-enoic acid","3-Bromo-5-methoxy-7-azaindole",".beta.-D-Glucopyranosiduronic acid, 4-[3-(1-naphthalenylcarbonyl)-1H-indol-1-yl]butyl","1H-Benzimidazol-2-yl 3-nitrobenzyl sulfide","Rosuvastatin","(7E)-4-Hydroxy-7-(1-hydroxypropan-2-ylidene)octahydro-3,9a-methanocyclopenta[c]oxocine-4(1H)-carboxylic acid","Bispyribac","Lys-Asn","4-(1-Methylbutyl)phenol","Leu-Met","4-fluorobenzoate","N,N',N''-Triacetylchitotriose","Dehydrocostus lactone","3-Fluoro-10H-phenothiazine","N-cyano-n'-(1,1-dimethylpropyl)-n'-3-pyridinyl-guanidine","1-[4,5-bis(hydroxymethyl)-3-methoxy-2-methylphenoxy]-3-methylbutane-2,3-diol","1H-Indole-1-propanoic acid, 3-(1-naphthalenylcarbonyl)-","6-O-(2-Methylpropanoyl)-.alpha.-D-glucopyranosyl .alpha.-D-glucopyranoside","Xanthosine","Citric acid","5-Oxo-1-propyl-2-pyrrolidineacetic acid","2-Chloro-N-[4-(1H-indol-3-yl)-1,3-thiazol-2-yl]acetamide","(-)-Quinic acid","2,6-Dioxo-4-piperidinecarboxylic acid","Osas#9","1-[(Benzyloxy)carbonyl]-2-piperidinecarboxylic acid","5-Hydroxy-1,3-benzoxathiol-2-one","4-Morpholinopropanesulfonic acid","Indole-3-acetyl-l-tryptophan",".beta.-Glutamic acid","Palatinose","3-Nitro-1H-pyrazole-5-carboxylic acid","2-Quinoxalinecarboxylic acid","Citrazinic acid","Tauroursodeoxycholic acid","6,7'-Dihydroxy-2,2'-dioxo-2H,2'H-[8,8'-bichromen]-7-yl hexopyranoside","Nocodazole","N-[Tris(hydroxymethyl)methyl]-3-amino-2-hydroxypropanesulfonic acid","Ganciclovir","Acetyl-L-threonine","Ethanesulfonic acid","2-[3-(1,1,2,2-Tetrafluoroethyl)-1H-pyrazol-5-yl]phenol","5-Nitrobenzene-1,2,3-tricarboxylic acid","Warfarin","Heptanedioic acid, 1-(2-cyclopentylidenehydrazide)","1-Hydroxy-1-(hydroxymethyl)-8,8-dimethyl-2-oxo-4a,6a,7,9-tetrahydro-4H-pentaleno[1,6a-c]pyran-5-carboxylic acid","Dorzolamide","trans,trans-Muconic acid","Benzyl 6-O-(4-carboxy-3-hydroxy-3-methylbutanoyl)hexopyranoside","6-Hydroxycoumarin","Bisphenol A","13,14-Dihydro-15-ketotetranorprostaglandin D2","Bisphenol E","1-Pyrenesulfonic acid","N-(6-Amino-1-butyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-N-methylbenzamide","Givinostat","Djenkolic acid","Ala-Tyr","2',4,4'-Trihydroxychalcone","(-)-camphanic acid","5-Ethyl-5-(propan-2-yl)imidazolidine-2,4-dione","Helvolic acid","(4R,4aR,6aS,11E,12aS,15S,16aR,21aS,21bS)-4-((2,6-Dideoxy-4-O-(2,6-dideoxy-.beta.-D-arabino-hexopyranosyl)-.beta.-D-arabino-hexopyranosyl)oxy)-22-hydroxy-15,21a-dimethyl-18,21-dioxo-1,2,3,4,4a,6a,7,8,9,10,12a,15,16,21,21a,21b-hexadecahydro-16a,19-(metheno)benzo[e]naphtho[2,1-m][1,4]dioxacyclopentadecine-14(18H)-carboxylic acid","Entecavir","1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol)","3-Pyridinecarboxylic acid, 2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazide","N-[(4-Methylphenyl)sulfonyl]benzencarbothioamide","7-Methyluric acid","Macluraxanthone","5-[(Chloroacetyl)amino]-2-hydroxybenzoic acid","Acetildenafil","3-(N-Morpholino)-2-hydroxypropanesulfonic acid","(2R)-2,4-Dihydroxy-3,3-dimethylbutanoic acid","His-Lys","His-ser","Citramalate","Dehydrocurvularin","Glyoxylate","1,2,4-Triazin-5-amine, N-([1,1'-biphenyl]-4-ylmethyl)-6-phenyl-3-(2-pyridinyl)-","3-Oxopentanoic acid","D-(-)-Isoascorbic acid","1-Methyluric acid","N-(3-Methoxyphenyl)-7H-purin-6-amine","4-(Phenylthio)benzoic acid","4-((N-(4-((N-Acetylvalylvalyl)amino)-3-hydroxy-6-methylheptanoyl)alanyl)amino)-2,4,5,6-tetradeoxy-6-methylheptonic acid","3-Oxo-1,8-octanedicarboxylic acid","4-{[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]amino}-4-oxobutanoic acid","2,2'-O-Cyclouridine","2-(4-Nitrobenzoyl)-N-phenylhydrazinecarboxamide","Galactose","5-Fluoro-1-benzothiophene-2-carboxylic acid","1-(3-Phenyl-6,7-dihydro-2H-pyrazolo[4,3-c]pyridin-5(4H)-yl)propan-1-one","3-(2-amino-2-oxoethyl)-5-methyl-hexanoic acid","Taurine","4-(2-Methyl-6-oxopyran-3-yl)butanoic acid","2-(2-Butoxyethoxy)acetic acid","2-(3-Chlorophenyl)-4-methyl-1H-imidazole-5-carboxylic acid","Methyl 2-carboxy-6-nitrobenzoate","Clemastanin B","3-[3-(2-Carboxyethyl)-4-methylpyrrol-2-methylidenyl]-2-indolinone","Lithocholic acid","3-(3,7-Dimethyl-2,6-octadienyl)-2,4-dihydroxy-6-(2-phenylethenyl)benzoic acid","1- Piperazinecarboxylic acid, 4-[3-(2,3-dihydro-2-oxo-6-benzoxazolyl)-3-oxopropyl]-, (3,5-dichlorophenyl)methyl ester","4-(4-Hydroxy-2-quinazolinyl)benzenesulfonamide","2-(2,3-Dimethylphenyl)-1,3-dioxo-5-isoindolinecarboxylic acid","Dihydroplumericinic acid","2-[(4-Chlorophenyl)acetyl]benzoic acid","Gastrodin","L-Tosylphenylalanyl chloromethyl ketone","Axitinib","Isobutyrylphloroglucinol","9-phenyl-1-(2,4,6-trihydroxyphenyl)nonan-1-one","3-Hydroxymethylmefenamic acid","3-Phenyl-2,4-quinolinedicarboxylic acid","[8]-Gingerol","N-(2-Hydroxy-3-methylbutanoyl)valine","5-Methoxy-4-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one","Fonsecin","6-Quinoxalinecarbonitrile, 1,2,3,4-tetrahydro-7-nitro-2,3-dioxo-","6-Heptynoic acid","Trinexapac","6-(Acetylamino)hexanoic acid","2-Hydroxy-2-[2-[(Z)-2-hydroxy-2,6-dimethyl-8-(7-oxofuro[3,2-g]chromen-4-yl)oxyoct-6-en-3-yl]oxy-2-oxoethyl]butanedioic acid","Topiramate","2-Oct-7-enylpentanedioic acid","Undecanoic acid","(6-Hydroxy-3-oxo-2,3-dihydro-4-pyridazinyl)acetic acid","5'-Methylthioinosine","trans-Aconitic acid","L-Cysteine-glutathione disulfide","(6E,10Z,14E)-6,14-Dimethyl-3-methylidene-2-oxo-3a,4,5,8,9,12,13,15a-octahydrocyclotetradeca[b]furan-10-carboxylic acid","(2S,2'R,3'R)-2-(2',3'-Dicarboxycyclopropyl)glycine","Indole-3-acetyl-l-isoleucine","Val-Ile","N-(tert-Butyl)-4-fluorobenzenesulfonamide","Ammelide","Withaferin A","1-Aminodecylidene bis-phosphonic acid","Phenylalanine","Amdinocillin","Thymidine 5'-monophosphate","2-Hydroxy-6-methyl-4-(trifluoromethyl)nicotinonitrile","N-3-Hydroxyoctanoyl-L-homoserine lactone","2'-Hydroxy-2,4,5,5'-tetramethoxychalcone","N-(4-Hydroxy-1-naphthyl)benzenesulfonamide","D-Glucosamine, 6-sulfate","L-Cysteinesulfinic acid","Uracil","Domoic acid","4,4-Dimethyl-1,3-cyclohexanedione","(2,5-Dioxotetrahydrofuran-3-yl)acetic acid","4-[(2E)-3-(3,4-Dihydroxyphenyl)prop-2-enoyl]oxy-2,3-dihydroxy-2-methylbutanoic acid","Trp-Trp","Diethyl 3,4-dihydroxy-2,5-furandicarboxylate","3-isopropylmalate","4-(Difluoromethoxy)-1H-indole-2-carboxylic acid","trans-Dehydrocurvularin","2,4-Bis(4-hydroxyphenyl)cyclobutane-1,3-dicarboxylic acid","4-Nitrobenzoic acid","2-(1H-Indol-3-ylmethylene)-1H-indene-1,3(2H)-dione","5,7-Diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ol","Geodin hydrate","Indiplon","4-Chloro-8-methoxy-5H-pyrimido[5,4-b]indole","L-Cystine","14,15-dehydro-16-epi-vincamine","N-(2-Hydroxy-5-nitrophenyl)-2-phenoxyacetamide","2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine","2-(4,4-Difluorocyclohexyl)acetic acid","N-Acetylglycylglycine","Brazilin","Malate","(Desmethyl)hydroxycerivastatin","5-Carboxyfluorescein","2-(Benzylthio)benzoic acid","2-Amino-4-chloro-3-hydroxybenzoic acid","Balofloxacin","7.alpha.,17.alpha.-Dimethyl-5.beta.-androstane-3.alpha.,17.beta.-diol glucuronide","[4-(1-acetyloxyprop-2-enyl)-2-methoxyphenyl] 2-methylpropanoate","(1R,6R)-6-Benzylcyclohex-3-enecarboxylic acid","Enterolactone","Pelanserin","Lomefloxacin","Cysteic acid","Decanoic acid, 3,5-dihydroxy-","N-(1-Methylpiperidin-4-yl)-4-nitrobenzamide","Val-Val","Linearoside (Gentiana)","5-Aminoisophthalic acid","Nicotinic acid mononucleotide","Bisdesmethoxycurcumin","Ser-Pro","Met-Asn","1-(3,4-Difluorophenyl)-5-oxo-3-pyrrolidinecarboxylic acid","Met-Asp","1-(2,4-Dihydroxyphenyl)-2-(4-fluorophenoxy)ethanone","5-hydroxy-2,2-dimethyl-10-(2-methylbut-3-en-2-yl)pyrano[3,2-g]chromen-8-one","Pyruvate","Methyl (1r,4as,9s,10s)-10-acetyloxy-5,9-dihydroxy-1,4a-dimethyl-2-oxo-7-propan-2-yl-10,10a-dihydro-9h-phenanthrene-1-carboxylate","Threonic acid","4-Hydroxy-2',5'-dichlorobiphenyl","6-hydroxyhexanoate","Heptadecanoic acid","Norepinephrine","7-Hydroxycoumarin-4-acetic acid","Dimethylglycine","3-Hydroxy-5-[2-(4-hydroxyphenyl)ethyl]phenyl .beta.-D-glucopyranoside","N-Acetyl-D-galactosamine 4-sulfate","Glutamine","3-Hydroxyphenylacetic acid","N-(6-Amino-1-benzyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-N-methylbenzamide","Mollicellin I","Gly-Pro-Arg-Pro-amide","Palmitic acid","Curculigoside","(E)-3-(4-Acetyloxy-2,3-dihydroxy-2,5,5,8a-tetramethyl-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl)prop-2-enoic acid","7-methoxy-6-(1,2,3-trihydroxy-3-methylbutyl)chromen-2-one","Trp-Leu","4-Hydroxy-3,5-dichlorobiphenyl","16-Hydroxyhexadecanoic acid","(2S)-(+)-5,5-Dimethyl-2-morpholineacetic acid","Ser-Phe","Averufin","D-aspartic acid","Tegaserod","Thr-Tyr","Resolvin D2","Esculin","(R,R)-cis-Diethyl tetrahydro-2,8-chrysenediol","Propionic acid","4,6-Dihydroxypyrimidine","N-(Phenoxyacetyl)phenylalanine","Ethyl 2-(3-chloropyridin-2-yl)-5-oxopyrazolidine-3-carboxylate","Xanthoangelol","N-Formyl-L-methionine","2-ethyl-2-hydroxybutyric acid","N-(4-Fluorophenyl)-4-methylbenzenesulfonamide","Gly-Val","1,3-Benzenediol, 4-chloro-6-[5-[[2-(4-morpholinyl)ethyl]amino]-1,2-benzisoxazol-3-yl]-","Nalidixic acid","Gatifloxacin","Gamma-glutamylmethionine","Robustaside A","Dihydroxyfumaric acid","DL-phenylalanine","Dl-lactate","2-(2-Naphthyl)-4-quinolinecarboxylic acid","Kipukasin I","Asn-Pro","Thr-Leu","Methyl 4-hydroxy-3,5-dimethoxybenzoate","2-Ethylhexyl dihydrogen phosphate","1-Methyl-1H-pyrazolo[3,4-d]pyrimidin-4-ol","N-(14-Methylpentadecanoyl)phenylalanine","3-Aminoadipic acid","Eugenitol","2,3-Dioxo-5-indolinecarboxylic acid","3-Methyl-2-thioxo-2,3,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-4(1H)-one","2-Methyl-3-phenyl-4-quinolinecarboxylic acid","Xanthine","D-alanine","1,3-Cyclobutanedicarboxylic acid, 2,4-diphenyl-, 1-(1-naphthalenyl) ester, (1.beta.,2R,3.alpha.,4R)-","5-{[(5-Methyl-2-furyl)methyl]amino}-5-oxopentanoic acid","Benzoic acid, 4-[(4,6-dihydroxy-5-methoxy-2,5-dimethyl-3-oxo-1-cyclohexen-1-yl)oxy]-2-hydroxy-3,6-dimethyl-, methyl ester","3H-spiro[1,3-benzothiazole-2,3'-indol]-2'(1'H)-one","(10E,15Z)-9,12,13-Trihydroxyoctadeca-10,15-dienoic acid","Trp-Pro","4-Aminobutyric acid(GABA)","Galactinol dihydrate","Glu-Lys","(Sulfanylsulfonyl)methane","Methyl 4,6-difluoro-1H-indole-2-carboxylate","1-Cyclopropyl-6-fluoro-7-chloro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid","Quisinostat","Aldosterone","PG 36:5","His-Cys","2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)ethanesulfonic acid","Maleic acid","3-Indoleacetic acid","(R)-Pantetheine","N-Acetyl-D-lactosamine","O-acetylserine","Indoxyl sulfate","(S)-10-Hydroxycamptothecin","S-(4-Fluorophenyl)mercapturic acid","Phosphorylcholine","6-(Trifluoromethyl)-1,4-dihydro-2,3-quinoxalinedione","Undecanedioic acid","2-Hydroxy-2-methylbutyric acid","Dihydroisoferulic acid","D-arabitol","Zinterol","Thr-Pro","10-Hendecenoic acid","Sedoheptulosan","3-Amino-4,4,4-trifluorobutanoic acid","3,4-Dihydroxyhydrocinnamic acid","[(4,6-Dimethyl-2-pyrimidinyl)amino]acetic acid","2-Hydroxy-3-(1H-indol-3-yl)butanoic acid","2-(3-Nitrobenzoyl)benzoic acid","Evodiamine","Cis-9-palmitoleic acid","4-Hydroxy-L-glutamic acid","4-Hydroxyphenylpyruvic acid","Purpactin A","3-Hydroxy-6-[[(E)-3-hydroxy-2,4-dimethylhept-4-enoyl]amino]-2,4-dimethyl-5-oxohexanoic acid","Aminomethylphosphonic acid","3-Benzyl-5-methyl-1,2-oxazole-4-carboxylic acid","(1S,3R)-1-Aminocyclopentane-1,3-dicarboxylic acid","1-palmitoyl-sn-glycero-3-phosphoglycerol","Polydatin","Ser-Trp","Tuberonic acid","6-Bromo-2-[2-(propan-2-yloxy)phenyl]quinoline-4-carboxylic acid","Amino[4-(benzyloxy)-3-methoxyphenyl]acetic acid","Cis-4-hydroxyproline","N-Cyclohexyl-N'-(3,5-dimethyl-1H-pyrazol-4-yl)thiourea","Celastramycin A","Geranyl diphosphate","N-(4-Ethylphenyl)benzenesulfonamide","3-Bromo-2-nitrobenzoic acid","N-Benzyl-2-naphthalenesulfonamide","Licoagroside B","3'-Hydroxyrepaglinide","3-Hydroxy-3-methyl-5-oxo-5-(((2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-(octan-3-yloxy)tetrahydro-2H-pyran-2-yl)methoxy)pentanoic acid","Pipecolate","L-(-)-3-Phenyllactic acid","Ser-Lys","3-Isopropylmalic acid","N.alpha.-(tert-Butoxycarbonyl)-L-aspartic acid","Deoxyribose","2,7-Dihydroxy-8-(5-hydroxy-4,8-dimethyl-7-methylidene-3-oxononyl)-4a,7-dimethyl-1,2,3,4,5,6,8,9,10,10a-decahydrophenanthrene-1-carboxylic acid","Riboflavin","N-Isovaleroylglycine","3,3-Dimethylglutaric acid","Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate","(2e,4e)-12-hydroxy-13-(hydroxymethyl)-3,5,7-trimethyltetradeca-2,4-dienedioic acid","Folic acid","Quinolin-8-ol","Deoxyinosine","Pyrrolidine-3-carboxylic acid","N-Arachidonoyl-.gamma.-aminobutyric acid","Antibiotic TAN 1446A","13-Hydroxy-6-(1-hydroxyethyl)-12,14-dimethyl-3-methylidene-15-nonyl-9-(propan-2-yl)-1-oxa-4,7,10-triazacyclopentadecane-2,5,8,11-tetrone","O-Succinyl-L-homoserine","Aminocyclopyrachlor","Leu-Tyr","N-[Tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid","2-oxoadipic acid","2,5-Dichlorothiophene-3-carboxylic acid","[(3,4,5-Trimethoxybenzoyl)amino]acetic acid","3-Formyl-2-hydroxybenzoic acid","7-methylthioheptyl glucosinolate","4-Chloro-N-(2-(hydroxyamino)-2-oxoethyl)benzamide","all-trans-4-Ketoretinoic acid","Phenol","Octadecanedioic acid","3-Hydroxyanthranilic acid","(2Z)-2-(.beta.-D-Glucopyranosyloxy)-3-phenyl-2-propenoic acid","[(4,5-Diphenyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetic acid","5S-Hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid","1H-Imidazo[1,2-a]indole-9-propanoic acid, 2,3,9,9a-tetrahydro-1,9-dihydroxy-2,2-dimethyl-3-oxo-.alpha.-(4-oxo-3(4H)-quinazolinyl)-","6,7-Bis(3-hydroxyphenyl)pteridine-2,4-diamine","Tazarotenic acid","Populoside","5-(4-Fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid","1.alpha.-Methyl-5.alpha.-androstan-3.alpha.,17.beta.-diol glucuronide","[(4-Hydroxy-1,1-dioxidotetrahydro-3-thienyl)amino]acetic acid","Glycine","Val-Ala","2,3-Dinorfluprostenol","Mitoglitazone","Leucenol","Glutaric acid","Glycine, N-[2-(3,5-difluorophenyl)acetyl]-L-alanyl-2-phenyl-, 1,1-dimethylethyl ester, (2S)-","1H-Indazole-3-carboxamide, 1-(5-fluoropentyl)-N-1-naphthalenyl-","8S-Hydroxy-4Z,6E,10Z-hexadecatrienoic acid","Salicylic acid ethyl ester","1-[(5-Bromo-2-thienyl)sulfonyl]-2-piperidinecarboxylic acid","3,4-Dihydro-3-oxo-2H-(1,4)-benzoxazin-2-ylacetic acid","Phosphatidylethanolamine lyso 17","2-(4-Methyl-1-piperazinyl)-5,6,7,8-tetrahydro-4-quinazolinol","2-(2-Bromophenyl)-2-((tert-butoxycarbonyl)amino)acetic acid","Phosphatidylethanolamine lyso 18","2,4-Thiazolidinedione, 5-(6-quinoxalinylmethylene)-","2-(12,14-Dioxo-9,10-dihydro-9,10-[3,4]epipyrroloanthracen-13-yl)acetic acid","o-Nitrobenzoic acid","N-(1H-Benzimidazol-2-yl)-3-cyanobenzamide","N-Acetylnorfloxacin","Phosphatidylethanolamine lyso 20","4-[(3,4,5-Trimethoxybenzoyl)amino]butanoic acid","5-aminolevulinic acid","6-Phenyl-1-(4-pyridinylmethyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid","4-Pyridoxic acid","5-Chloro-2-(4-morpholinyl)-4-pyrimidinecarboxylic acid","2-{[((2Z)-4-Phenyl-1,3-thiazol-2(3H)-ylidene)amino]carbonyl}benzoic acid","N-Acetyl-L-methionine","Griseophenone B","7-Keto-8-aminopelargonic acid","Cytochalasin A","Doxorubicin","Efavirenz","1-Pyrrolidinecarboxamide, N-[3-[[5-bromo-4-[[2-(1H-imidazol-5-yl)ethyl]amino]-2-pyrimidinyl]amino]phenyl]-","L-Glutathione, reduced","2,3-Pyridinedicarboxylic acid","1,3,7-Trimethyluric acid","5-(3-Nitrophenyl)-2-furoic acid","3-[4-[Acetyl(hydroxy)amino]butylcarbamoyl]-5-[3-[acetyl(hydroxy)amino]propylamino]-3-hydroxy-5-oxopentanoic acid","Hydroxypyruvic acid dimethyl ketal phosphate","N-acetyl-l-glutamate","3-Coumaric acid","4(1H)-Quinolinone, 7-chloro-2-methyl-","Psoromic acid","Boc-(R)-.alpha.-(4-fluorobenzyl)proline","5-[2-(1H-Tetraazol-5-yl)ethyl]-1H-tetraazole","2-(N-Morpholino)ethanesulfonic acid","Phosphatidylcholine 16:0-18:2","Rubinaphthin A","1-Benzyl-1H-pyrazolo[3,4-d]pyrimidin-4-ol","Penicillic acid","N-Benzoyl-2-hydroxybenzamide","Uridine","Ethanone, 1-(5-hydroxy-1-pentyl-1H-indol-3-yl)-2-(2-methoxyphenyl)-","(E)-7-(4-Methoxy-5-methyl-6-oxopyran-2-yl)-5-methyloct-6-enoic acid","[1,2,4]Triazolo[4,3-a]quinazolin-5(1H)-one, 2,4-dihydro-4-methyl-1-thioxo-","(3e,7e,11e,15e)-5,9,13,17,18-pentahydroxy-4,6,8,10-tetramethyl-2-[(e)-2-methylbut-2-enyl]nonadeca-3,7,11,15-tetraenedioic acid","1-Acetylpiperidine-2-carboxylic acid","(6E)-8-Methyl-6-nonenoic acid","(5E)-5-(3,4-Dimethoxybenzylidene)-4-hydroxy-1,3-thiazol-2(5H)-one","Proline","(+)-2-Hydroxyisocaproic acid","6-(4-Morpholinyl)-1H-purine","(2s)-2-[(3r,7r,8r,8as)-3,4'-dihydroxy-4,4,7,8a-tetramethyl-6'-oxospiro[2,3,4a,5,6,7-hexahydro-1h-naphthalene-8,2'-3,8-dihydrofuro[2,3-e]isoindole]-7'-yl]pentanedioic acid","N-(Naphthalen-2-yl)-2-sulfanylacetamide","Dihydrexidine","3-(2-Chlorophenyl)-1H-pyrazole-5-carboxylic acid","2-[Bis(2-Hydroxyethyl)Ammonio]Ethanesulfonate","Aspartic acid","3-Methyl-2-(3-oxo-3H-benzo[d]isothiazol-2-yl)pentanoic acid","P-coumaraldehyde","Dolasetron","4-Methyl-N-[4-(phenylamino)phenyl]benzenesulfonamide","N-Acetyl-L-glutamic acid","3-Cyclohexyl-2-sulfanyl-4(3H)-quinazolinone","Alpha-ketoglutarate","3-(4-Fluorophenyl)-2-thioxo-2,3-dihydro-4(1H)-quinazolinone","D-(+)-Ribonic acid .gamma.-lactone","tert-Butyl 3-(trifluoromethyl)-1,4,5,7-tetrahydro-6H-pyrazolo[3,4-c]pyridine-6-carboxylate","8-Bromo-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole","2,2-Dimethylglutaric acid","Rutarin","Sulfamonomethoxine","Dihydroconiferyl alcohol","S-Carboxymethyl-L-cysteine","Gly-Phe-.beta.-naphthylamide","Sulfoacetic acid","8-(2,3-dihydroxy-3-methylbutyl)-7-methoxychromen-2-one","Propentofylline","DL-Vanillylmandelic acid","1,3-Dimethyl-6-benzylaminouracil","Prohexadione","Ethyl 3-methyl-1H-pyrazole-4-carboxylate","1H-Pyrazole-3-carboxylic acid, 5-(2,4-difluorophenyl)-","5,13,15-Trihydroxy-9-methyl-10-oxabicyclo[10.4.0]hexadeca-1(12),13,15-triene-3,11-dione","2-[(4,6-diamino-1,3,5-triazin-2-yl)thio]-ethanesulfonic acid","2-[2-[19-acetamido-6-(3,4-dicarboxybutanoyloxy)-16,18-dihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic aci","Phenol, 3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]-","1-O-Hexadecyl-2-O-ethyl-sn-glycero-3-phosphocholine","5-Fluoro-2-[(methylsulfonyl)amino]benzoic acid","1,3-Dimethyl-8-(3-pyridinyl)-3,9-dihydro-1H-purine-2,6-dione","2-Isopropylmalic acid","(12Z,15Z)-9,10,11-Trihydroxyoctadeca-12,15-dienoic acid","Sialyl Lewis X","3,4-Dihydroxycinnamic acid (L-alanine methyl ester) amide","Glu-Gly-Glu","Phenazine-1 6-dicarboxylic acid","4-decyl-3-hydroxy-5-oxooxolane-2,3-dicarboxylic acid","6-(1-Pyrrolidinyl)-1H-purine","Ethyl 4-hydroxy-1,5-naphthyridine-3-carboxylate","[DAla2] .beta.-Casomorphin (1-3), amide, bovine","Raltegravir","Ser-His","2-[(4-Chlorobenzoyl)amino]benzoic acid","Senegenin","Suberic acid","Vincanidine","2-(5-Iodo-2-methyl-1H-indol-3-yl)ethanamine","D-Xylulose","7.alpha.-Hydroxy-3-oxo-4-cholestenoic acid","4-Fluoro-2,6-dinitrophenol","2-(2-Methoxyphenyl)-4-quinolinecarboxylic acid","Acamprosate","4-Hydroxy-3-(3-methyl-2-butenyl)benzaldehyde","2-(Trifluoromethyl)thiophenol","2,4-Dinitro-6-(1H-tetrazol-1-yl)phenol","L-(+)-Erythrulose","6-Phosphogluconic acid","Roseoflavin","Methanedisulfonic acid","3-Hydroxy-6-methylheptyl 2-O-.beta.-D-glucopyranosyl-.beta.-D-glucopyranoside","Methyl 6-(acetyloxy)-1,3,7,11-tetrahydroxyabieta-8,11,13-trien-18-oate","Val-Asp","3-(2-Pyrimidinyl)propanoic acid","Leu-Trp","13-Hydroxy-9Z,11E-octadecadienoic acid","1H-Imidazo[4,5-c]pyridine-6-carboxylic acid, 1-[[4-(dimethylamino)-3-methylphenyl]methyl]-5-(2,2- diphenylacetyl)-4,5,6,7-tetrahydro-, (6S)-","2,4,5-trichlorophenoxyacetate","3-Sulfopropanoic acid","Modafinil acid","4(1H)-Pyridinone, 5-acetyl-2,3-dihydro-2,6-dimethyl-","Benzoic acid, 4-[[tetrahydro-2-(3-hydroxy-1-butenyl)-5-oxo-3-furanyl]amino]-","3-Hydroxy-2-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy-3-methoxycarbonylpentanedioic acid","Heptanedioic acid, 1-[2-[(2-carboxyphenyl)methylene]hydrazide]","4-Phenyl-3,4,5,6-tetrahydrobenzo[h]quinazoline-2-thiol","9-Oxo-10(E),12(E)-octadecadienoic acid","9,10-Dihydrojasmonic acid","Cinobufagin","Val-Arg","Gamma-glu-glu","5-Fluorouridine","N-oleoyl-phenylalanine","5-Chloro-4(3H)-quinazolinone","(methylthio)acetic acid","4-Chloro-2-[(2-thienylcarbonyl)amino]benzoic acid","4-Fluoro-N-phenylbenzenesulfonamide","3-Hydroxy-2-[(Z)-oct-2-enyl]pentanedioic acid","1,7,8-Trihydroxy-3-methyl-2,3,4,7-tetrahydro-1H-benzo[a]anthracen-12-one","Secologanoside","Cyclo(alanylisoleucyl)","Indacaterol","[4-Chloro-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetic acid","FAHFA 26:0","Methyl 2-[(3-formamido-2-hydroxybenzoyl)amino]-3-hydroxybutanoate","4-(1,3-Oxazol-5-yl)benzoic acid","Atorvastatin","N-(4-Aminobenzoyl)-L-glutamic acid","6-Chloro-2-(trifluoromethyl)quinolin-4-ol","Dodecanoic acid","Ethyl 6-ethyl-4-hydroxy-3-quinolinecarboxylate",".alpha.-Keto-.gamma.-(methylthio)butyric acid","3-Hydroxy-N-(2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-2-naphthamide","Protubonine A","[Glu1] TRH","D-Glucose, 2-deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-","5-Methyl-2-(methylsulfanyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-ol","1H-Benzimidazol-2-ylcyanamide","Belinostat","5-[(Benzylsulfanyl)methyl]-2-furoic acid","4,6'-Dihydroxy-2,2',4',6-tetrachlorobiphenyl","(E)-1-(4-Hydroxy-2-methoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one","(S)-3-Benzyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione","m-Hydroxycocaine","L-pyroglutamic acid","Marbofloxacin","4-hydroxybenzenesulfonic acid","Traumatic Acid","2-Hydroxy-2-(1-naphthyl)propanoic acid","2-Methyl-1H-imidazole-5-sulfonyl chloride","2-Chloro-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)acetamide","Clofarabine","N-(1-Phenyl-3,6-diazatricyclo[4.3.1.1~3,8~]undec-9-yl)thiourea","[(1S)-1-Benzyl-2-[[5-(3-methyl-2H-indazol-5-yl)-3-pyridyl]oxy]ethyl]amine","3-(Difluoromethoxy)-4-methoxybenzoic acid","Val-Gly-Val","4-(Trifluoromethyl)quinoline-2,7-diol","N-(4-Hydroxyphenyl)glycine","Chalepensin","D-Fructose","Methyl 3-methyl-4-nitro-1H-pyrazol-5-yl ether","Xanthohumol","Embelin","13,14-Dihydro-15-ketotetranorprostaglandin F1.beta.","N-(3-Chloro-4-fluorophenyl)-N'-(5-methyl-3-isoxazolyl)urea","7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine, N3-cyclopropyl-7-[[4-(1-methylethyl)phenyl]methyl]-","11beta-hydroxyprogesterone","Futalosine","3-[5-(Ethoxycarbonyl)-2,4-dimethyl-1H-pyrrol-3-yl]propanoic acid","2-Ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]benzoic acid","9-Hydroxyjasmesoside","Gly-Arg","Gly-Gly-Gly","6-Maleimidocaproic acid","Asn-Met","(.alpha.S,1S,2R)-.alpha.-Amino-2-carboxycyclopropaneacetic acid","Bergenin","(1R,4R,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid","2-(2-Thienylcarbonyl)benzoic acid","Picrotin","Succinate","Volemitol","2-hydroxy-3-methylbutyric acid","5-(Aminosulfonyl)-2-methoxybenzoic acid","4-(Difluoromethoxy)benzoic acid","Porphobilinogen","4-Methylcyclohexaneacetic acid","Midafotel","N-Fluorenylacetamide","Ile-Tyr","Gln-Ser","1-Methyl-3-indoleacetic acid","2-Heptylquinolin-4(1H)-one","Aurantiamine","Albiflorin","L-.gamma.-Glutamyl-L-glutamic acid","6-O-Pentopyranosyl-1-O-((2,6,6-trimethylcyclohex-1-en-1-yl)carbonyl)hexopyranose","(E)-1-Hydroxy-2-methylbut-2-enyl 4-diphosphate","Ricinoleic acid","Clavulanic acid","3',5'-Di-.beta.-D-glucopyranosylphloretin","N-acetyl-dl-serine","3-[(Methylsulfonyl)amino]benzoic acid","3a,4,5,9b-Tetrahydro-3H-cyclopenta[c]quinoline-4,8-dicarboxylic acid","4,8-Dimethylquinolin-2-ol","Cys-Cys","5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-6-methyl-4-(5-methyl-2-thienyl)-2-oxo-, ethyl ester","2-Phthalimidoglutaric acid","Citrinin","2-(3',3'-Dimethyl-6-nitrospiro[chromene-2,2'-indoline]-1'-yl)ethanol","Acetyl-.beta.-alanine","15-Ketoiloprost","Desaminosulfamethazine","(2,4-Dioxo-3,4-dihydro-2H-pyrimidin-1-yl)acetic acid","3-Amino-3,5-dihydro-4H-pyrimido[5,4-b]indol-4-one","Tetrahydroharmine","Boc-N-methyl-L-glutamic acid .gamma.-benzyl ester","3-Methyladipic acid","Shikimate","Sotalol","Niacinamide","Salsolinol","Diaminopimelic acid","N-Tris(hydroxymethyl)methyl-4-aminobutanesulfonic acid","Kojic acid","7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid","3-isopropyl-1,2-benzenediol","Penciclovir","2-dehydro-3-deoxy-d-gluconate","N-acetylneuraminate","Aloin","N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)hydrazinecarbothioamide","N-(3-Methylbutanoyl)valine","Fumarate","2,3-Dinorthromboxane B1","5-(4-Hydroxybenzylidene)-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione","2-Furancarboxylic acid","Phenol, 3-[[6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-","Nicotianamine","Norleucine","2-Cyclohexen-1-one, 4,6-dihydroxy-3-(3-hydroxy-2,5-dimethylphenoxy)-5-methoxy-2,5-dimethyl-","Olaparib","Luotonin F","Barbital","(1R,4S,5S,6S)-4-Amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide","3-hydroxyisovaleric acid","Formoterol","15-Ketolatanoprost (free acid)","1,1-Dioxo-1,2-thiazolidine-3-carboxylic acid","8-Cyclopentyl-1,3-dimethylxanthine","3-Hydroxy-2-octylpentanedioic acid","N-(2-Furanylmethyl)adenosine","Thiomiltefosine","N-Methyl-.gamma.-oxo-3-pyridinebutanamide","5-Isopropyl-3-isoxazolecarboxylic acid","Cladribine","Ethyl 4-(2-chloro-6-fluorophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylate","Propyl thiosulfate","2-(1H-indol-3-yl)-N-((1-methyl-1H-pyrrol-2-yl)methyl)ethanamine","Dinoterb","8-(2-hydroxy-3-methoxy-3-methylbutyl)-7-methoxychromen-2-one","Platencin","Hippuric acid","Phosphatidylcholine lyso 18:0","NCGC00385221-01","Phosphatidylcholine lyso 18:1","Dimethachlor cga369873","2-[4-(2-Thienylcarbonyl)phenyl]propanoic acid","1-[4-(Acetylamino)phenyl]-5-oxo-3-pyrrolidinecarboxylic acid","2,2'-Sulfonylbis(4-chlorophenol)","1-[3-Carboxy-3-[[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]amino]propyl]pyridin-1-ium-3-carboxylate","Phe-Asp","2-[(Diphenylacetyl)amino]benzoic acid","Shikonin","Enofloxacin","17-Phenyltrinor-13,14-dihydroprostaglandin A2","2-hydroxy-3,4-dimethoxybenzoic acid","1H-Indole-1-pentanoic acid, 3-(1-naphthalenylcarbonyl)-","Benz[a]anthracene-1,7,12(2H)-trione, 3,4-dihydro-8-hydroxy-3-methyl-, (3S)-","Captopril","4-(Methylmercapto)phenol","Eplerenone hydroxy acid","3-Hydroxy-5-((3-hydroxy-6-methyl-5-(pentofuranosyloxy)octanoyl)oxy)-6-methyloctanoic acid","Shanzhiside","Glutaconic acid","3-[[(2R)-2-[2-(4-Methyl-1-piperidinyl)ethyl]-1-pyrrolidinyl]sulfonyl]phenol","N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid","(3-Bromo-5-chloro-2-hydroxyphenyl)phenylmethanone","Inosine","DL-tyrosine","Lumichrome","[(2-Aminoethyl)sulfanyl]sulfonic acid","Methylenediphosphonic acid","Diprotin B","7-Chloro-8-methyl-2-phenylquinoline-4-carboxylic acid","Benzoylecgonine","Lys-Gly","3-(5-Hydroxy-2,2,7,8-tetramethyl-6-oxo-7,8-dihydropyrano[3,2-g]chromen-10-yl)hexanoic acid","Ala-Glu","Ureidosuccinic acid","2-Chloro-N-(4H-1,2,4-triazol-3-yl)acetamide","Arg-Met","2-Ethyl-L-glutamic acid","2-Ethyl 4-methyl 3,5-dimethyl-1H-pyrrole-2,4-dicarboxylate","1H-Indazole-1-pentanoic acid, 3-[[[1-(aminocarbonyl)-2,2-dimethylpropyl]amino]carbonyl]-","(2E,6E,12E)-19-(2-Amino-2-oxoethyl)-9,11-dihydroxy-8-methoxy-10,12,14-trimethyl-15-oxohenicosa-2,6,12-trienedioic acid","2-Aminoethyl dihydrogen phosphate","Vanylglycol","Sebacic acid","N-acetylglutamate","3-{[2-(Difluoromethoxy)phenyl]methoxy}benzoic acid","D-Gluconic acid, .delta.-lactone","3-Dehydroshikimic acid","2-Amino-4,5-difluorobenzoic acid","3-Hydroxyphenazepam","(1-{[(tert-Butoxycarbonyl)amino]methyl}cyclohexyl)acetic acid","D-Arabinonic acid","Homovanillic acid sulfate","5-Nitro-2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazole","16-Epiestriol","3-O-p-Coumaroylquinic acid","Lys-Thr","Stictic acid","(2S)-4-tert-Butoxycarbonyl-1-carbobenzoxy-piperazine-2-carboxylic acid","Methyl 3-hydroxy-5-nitrobenzoate","2,2'-((2,6-Dihydroxybenzyl)azanediyl)diacetic acid","myo-Inositol","Microcystin LR","3-phospho-d-glycerate","1-O-((2E,4E)-9-Carboxy-8-hydroxy-2,7-dimethylnona-2,4-dienoyl)-.beta.-D-glucopyranose","17.beta.-Estradiol 3-.beta.-D-glucuronide","Gly-Gly-Phe","Asp-Ile","Dodecanedioic acid","2,4-Dodecadienamide, N-(p-hydroxyphenethyl)-, (E,E)-","6-(Benzylsulfanyl)-9H-purin-2-amine","(1Z)-1-(3-Ethyl-5-hydroxy-1,3-benzothiazol-2-ylidene)acetone","(4-Aminophenyl)phosphonic acid","Pro-Val","Pentosidine","N-(4-Chloro-3-nitrobenzoyl)glycine","9-(5-O-Methylpentofuranosyl)-1,9-dihydro-6H-purin-6-one","1-(Carboxymethyl)-2,2,3,3-tetrafluorocyclobutanecarboxylic acid","4H-Thieno[3,2-b]pyrrole-5-carboxamide, 2-chloro-N-[2-(3,4-diethoxyphenyl)ethyl]-4-methyl-","4-(4-Chlorobenzoyl)benzoic acid","Leu-Gln","2'-Deoxycytidine 5'-monophosphate","Leu-Glu","[(3,5-Difluorophenyl)amino](oxo)acetic acid",".beta.-Hydroxyphenylalanine","3-(Cyclohexylamino)-2-hydroxy-1-propanesulfonic acid","4-Isopropyl-3-methylphenol","Isogibberellin A3","Isocaproic acid","Val-Ser","Orotic acid",".beta.-Cyano-L-alanine","Methylmalonic acid","4-Formylbenzenesulfonamide","2,4'-Dihydroxybenzophenone","(9a-hydroxy-3,8a-dimethyl-5-methylidene-2-oxo-4,4a,6,7,8,9-hexahydrobenzo[f][1]benzofuran-8-yl) acetate","Lactitol","D-Mannitol 1-phosphate","DL-2,3-Diaminopropionic acid","5S,12R-Dihydroxy-6Z,8E,10E,14Z-eicosatetraene-1,20-dioic acid","Digalacturonic acid","Tetracycline","(z)-2-methyl-4-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybut-2-enenitrile","Triciribine","3-(3,3,3-Trifluoropropylsulfanyl)propanoic acid","N-[3-(5-Sulfanyl-1H-tetraazol-1-yl)phenyl]acetamide","Benzenebutanamide, N-(4-oxo-4H-3,1-benzothiazin-2-yl)-","3-{[(1Z)-4-(4-Hydroxyphenyl)phthalazin-1(2H)-ylidene]amino}phenol","Oxypurinol","5'-Deoxyadenosine","7-Diethylaminocoumarin-3-carboxylic acid","1,9b-dihydroxy-6,6,9a-trimethyl-1,5,5a,7,8,9-hexahydrobenzo[e][2]benzofuran-3-one","(1S,3R,4S,5R)-1,3,5-Trihydroxy-4-(((2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl)oxy)cyclohexanecarboxylic acid","Mitragynine","DL-.alpha.-Lipoic acid","Cynaropicrin","Dimethyl-5-sulfoisophthalate","Azelaic acid","(S)-Nitroblebbistatin","2-(2,6-Difluorophenyl)-1,3-thiazole-4-carboxylic acid","1,3-Cyclohexanedicarboxylic acid","N-(2,6-Dimethylphenyl)-N'-(2-thienylcarbonyl)thiourea","Dihydroorotate","3-Amino-4-methoxybenzenesulfonic acid","Propylphosphonic acid","Loganic acid","3-Hydroxy-5-methoxy-3-(methoxycarbonyl)-5-oxopentanoic acid","2,5-Furandicarboxylic acid","5-Fluoro-1H-indazole-3-carboxylic acid","7-Oxo-7H-benzo[e]perimidine-4-carboxylic acid","2-Phenylethyl 6-O-((2S,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl)-.beta.-D-glucopyranoside","1H-indol-4-ol","(2r,3s,4s,5r,6r)-6-[1,7-bis(4-hydroxyphenyl)heptan-3-yloxy]-5-[(2s,3r,4r)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy-2-[[(2s,3r,4r)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxymethyl]oxane-3,4-diol","Deoxycytidine","5-Bromopyridine-3-carboxylic acid","Norvaline","4-Acetyl-N-[3-(2-amino-2-oxoethoxy)phenyl]-3-ethyl-5-methyl-1H-pyrrole-2-carboxamide","2,2'-[(Phosphonomethyl)imino]diacetic acid","Leu-Gly","(2,5-Dioxo-1-pyrrolidinyl)acetic acid","N-oleyl-leucine","Benzoin"],"additional_accession":[]},"is_claimable":false,"name":"Gut Microbiota Contributes to Heat Tolerance Through Metabolic Remodeling and Suppression of Thermogenesis in Chickens","description":"Background The gut microbiota is increasingly recognized as a key regulator of host metabolic adaptation to environmental challenges. However, whether breed-specific gut microbiota contributes to variation in heat tolerance among poultry breeds remains unclear. This study used Cyan-shank partridge chickens, a native Chinese breed with superior environmental adaptability, to investigate the role of the gut microbiota in heat tolerance and its underlying mechanisms. Results Cyan-shank partridge chickens exhibited a higher inflection point temperature of rectal temperature and greater tolerance to heat stress than Arbor Acres (AA) broilers. Under cyclic heat stress, Cyan-shank partridge chickens maintained lower body temperatures, superior growth performance, and reduced expression of thermogenesis-related genes in skeletal muscle and liver. Concurrently, Cyan-shank partridge chickens exhibited lower cecal microbial α-diversity and a distinct microbial community structure compared with AA broilers. Fecal microbiota transplantation (FMT) of Cyan-shank partridge chickens derived microbiota into AA broilers improved growth performance and reduced the expression of the thermogenesis-related genes under heat stress. FMT also substantially remodeled the recipient gut microbiota, decreasing the abundance of Bacteroides while enriching several potentially beneficial taxa, including Limosilactobacillus and Phascolarctobacterium. Furthermore, untargeted metabolomics revealed profound alterations in microbial metabolic functions, particularly in pathways related to the tricarboxylic acid cycle, amino acid metabolism, and neurotransmitter metabolism. These metabolic functional changes support the potential mechanisms by which the altered microbiota may contribute to the observed improvements. Conclusions These findings demonstrate that the gut microbiota contributes to the superior heat tolerance of Cyan-shank partridge chickens and that this phenotype can be partially transferred through FMT, accompanied by reduced thermogenic activity in recipient broilers. This study provides a potential microbiota-based strategy for improving the heat tolerance of commercial broilers.","dates":{"publication":"2026-06-18","submission":"2026-06-18"},"accession":"MTBLS14785","cross_references":{}}