MetaboLightsapplication/xmlftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14845/m_MTBLS14845_LC-MS_negative_hydrophilic-interaction-liquid-chromatography_v2_maf.tsvftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14845/m_MTBLS14845_LC-MS_positive_hydrophilic-interaction-liquid-chromatography_v2_maf.tsvftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14845/a_MTBLS14845_LC-MS_positive_hydrophilic-interaction-liquid-chromatography-1.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14845/a_MTBLS14845_LC-MS_positive_hydrophilic-interaction-liquid-chromatography.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14845/i_Investigation.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14845/a_MTBLS14845_LC-MS_negative_hydrophilic-interaction-liquid-chromatography-1.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14845/a_MTBLS14845_LC-MS_negative_hydrophilic-interaction-liquid-chromatography.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14845/s_MTBLS14845.txtprimary200OKftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS14845<p>Metabolite features were annotated after peak extraction and preprocessing. Feature annotation was based on accurate mass, retention time, isotope and adduct information, and MS/MS spectral matching when available. The processed feature table was used for metabolite structure annotation and downstream statistical analysis. Features with insufficient quality were removed during preprocessing, including features with more than 50% missing values and features with RSD greater than 50% in quality control samples.</p>MetaboLightsPublicLiquid Chromatography MS - positive - hydrophilic-interaction-liquid-chromatographyLiquid Chromatography MS - negative - hydrophilic-interaction-liquid-chromatography<p>Chromatographic separation was performed using an HILIC method. For AB Sciex TripleTOF 6600 assays, samples were separated on an Agilent 1290 Infinity LC UHPLC system. For Thermo Scientific Orbitrap Exploris 480 assays, samples were separated on a Thermo Scientific Vanquish UHPLC system. A Waters ACQUITY UPLC BEH Amide column (1.7 um, 2.1 mm x 100 mm) was used. The column temperature was maintained at 25 C, the flow rate was 0.5 mL/min, and the injection volume was 2 uL. Mobile phase A consisted of water containing 25 mM ammonium acetate and 25 mM ammonium hydroxide, and mobile phase B was acetonitrile. The gradient was 95% B from 0 to 0.5 min, 95-65% B from 0.5 to 5 min, 65-40% B from 5 to 5.5 min, 40-95% B from 5.5 to 6 min, and 95% B from 6 to 8 min. Samples were kept at 4 C in the autosampler and analyzed in randomized order. Pooled QC samples were inserted throughout the analytical sequence to monitor system stability and data reliability.</p>Early microbial and metabolic remodeling of the neovagina after laparoscopic peritoneal vaginoplasty in MRKH syndrome.Shantou University Medical CollegeYUXUE WANGvestibular dimple secretionpooled vaginal/neovaginal secretionneovaginal secretionmass spectrometry assay<p>Samples were thawed slowly at 4 C. An appropriate aliquot of each sample was mixed with precooled methanol/acetonitrile/water (2:2:1, v/v/v), vortexed, sonicated at low temperature for 30 min, incubated at -20 C for 10 min, and centrifuged at 14000 g for 20 min at 4 C. The supernatant was collected and vacuum dried. Before LC-MS analysis, the dried extract was reconstituted in 100 uL acetonitrile/water (1:1, v/v), vortexed, and centrifuged at 14000 g for 15 min at 4 C. The resulting supernatant was used for untargeted LC-MS metabolomics analysis. Pooled quality control samples were prepared by mixing aliquots from study samples and were used to monitor analytical stability.</p>Homo sapienshttps://www.ebi.ac.uk/metabolights/MTBLS14845Dan Xiong. Shantou University Medical College. sunny543@126.com.YUXUE WANG. Shantou University Medical College. 564635712@qq.com.<p>Raw LC-MS data were converted to mzXML format using ProteoWizard MSConvert. The converted files were processed using XCMS for peak detection, peak alignment, retention time correction, and peak area extraction. Metabolite feature annotation was performed after peak extraction. Data preprocessing included removal of ion features with more than 50% missing values, missing value imputation using the KNN method, and filtering of features with relative standard deviation (RSD) greater than 50% in quality control samples. Quality control assessment was performed before downstream statistical analysis.</p>Timepoint564635712@qq.com<p>Preoperative vestibular dimple secretion samples (PRE) were collected before laparoscopic peritoneal vaginoplasty, and postoperative day 14 neovaginal secretion samples (P14D) were collected from the neovagina after surgery. All samples were obtained from patients with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome using sterile collection procedures, transferred into sterile tubes, and stored at low temperature until untargeted LC-MS metabolomics analysis. Pooled quality control samples were prepared by combining aliquots from study samples and were inserted throughout the analytical sequence to monitor system stability and data reliability.</p>MetabolomicsAgilent 1290 Infinity LC UHPLCbiological sampleMetabolomicsThermo Scientific Vanquish UHPLCuntargeted analysisLiquid chromatography-mass spectrometrypooled vaginal/neovaginal secretionquality control sampleHomo sapiensneovaginal secretionThermo Scientific Orbitrap Exploris 480Mayer-Rokitansky-Kuster-Hauser syndromevestibular dimple secretionXCMSAB SCIEX TripleTOF 6600Agilent 1290 Infinity LC UHPLCbiological sampleMetabolomicsThermo Scientific Vanquish UHPLCuntargeted analysisLiquid chromatography-mass spectrometrypooled vaginal/neovaginal secretionquality control sampleHomo sapiensneovaginal secretionThermo Scientific Orbitrap Exploris 480Mayer-Rokitansky-Kuster-Hauser syndromevestibular dimple secretionXCMSAB SCIEX TripleTOF 6600<p>Mass spectrometry was performed using electrospray ionization in both positive and negative ion modes. For AB Sciex TripleTOF 6600 assays, MS data were acquired on an AB Sciex TripleTOF 6600 Q-TOF mass spectrometer. Source parameters were Gas1 60, Gas2 60, curtain gas 30 psi, ion source temperature 600 C, and ion spray voltage +/-5500 V. The MS1 scan range was m/z 60-1000 with an accumulation time of 0.20 s/spectrum. The MS/MS scan range was m/z 25-1000 with an accumulation time of 0.05 s/spectrum. Information-dependent acquisition was performed in high-sensitivity mode with declustering potential +/-60 V, collision energy 35 +/- 15 eV, isotope exclusion 4 Da, and 10 fragment spectra collected per scan.</p><p><br></p><p>For Thermo Scientific Orbitrap Exploris 480 assays, MS data were acquired on a Thermo Scientific Orbitrap Exploris 480 mass spectrometer. Source parameters were Gas1 50, Gas2 2, ion source temperature 350 C, spray voltage 3500 V in positive ion mode, and spray voltage 2800 V in negative ion mode. The MS1 scan range was m/z 70-1200 with a resolution of 60000 and an accumulation time of 100 ms. MS/MS data were acquired using a segmented acquisition method over m/z 70-1200 with a resolution of 60000, an accumulation time of 100 ms, and a dynamic exclusion time of 4 s.</p>Staurosporine2(1h)-pyridinoneSolanidineMorphine n-oxideN-(octadecanoyl)sphing-4-enine-1-phosphocholine2,3-diethylpyrazine1-o-octadecyl-sn-glyceryl-3-phosphorylcholineStearoyl ethanolamideButamifosPantothenolMethapyrileneL-Histidine5-methylbenzotriazoleN-(omega)-Hydroxyarginine4-[5-(4-hydroxy-3-methoxyphenyl)-3,4-dimethyloxolan-2-yl]-2-methoxyphenolIle-thr(-)-quebrachitolDL-prolineThymoquinoneD-erythro-sphingosine-1-phosphateAmphetamine4-androsten-17.beta.-ol-3-one glucosiduronate2,2,6,6-tetramethyl-4 piperidoneLupinineDiphenamid3-cyclohexyl-6-(dimethylamino)-1-methyl-s-triazine-2,4(1h,3h)-dioneBrassicasterolIpratropiumLipoxin a4CyclohexylamineTributylphosphine oxideNorgestimatePilocarpineL-Pipecolic acidMyristoyl-l-carnitine(-)-caryophyllene oxideArginineEurycomalactone2-aminoacetophenoneCinosulfuron3-hydroxybutyrylcarnitineBoldioneMyxalamid bCyhalothrin5-androstene-3.beta.,17.beta.-diolLeucylleucine4-hydroxymandelonitrile1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-n,n-dimethyl4-hydroxy-3-methoxybenzyl alcoholN6-Methyl-L-lysineL-carnitineTetrabenazineFexofenadineMaltopentaose(5.alpha.)-androstane-3,11,17-trioneN-lauroyl-d-erythro-sphinganineIsophorone.epsilon.-caprolactamOleamide2-aminobenzimidazoleMethylergonovineHeliotrineAflatoxin g2LidocaineCyazofamidProscillaridin aMoxonidineDL-arginineAnthranilic acid (Vitamin L1)RitonavirSolanidine base + o-hex-hexXanthurenic acidSialyl lewis x5-methoxydimethyltryptamineFucosterolAflatoxin b2AcetylglycineOctaethylene glycol1,2-dioleoyl-sn-glycero-3-phosphatidylcholineIcariinBrucineCrustecdysoneN-hexanoyl-l-homoserine lactoneGln-proChymostatinPyraclonilDihydrotachysterolBenzyl alcoholRutinose1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphoserineA-methylserineAlprazolamMethylguanidine2-oxo-5-(3,3-dimethylguanidine-1-yl)pentanoic acidL-saccharopine1-(1z-octadecenyl)-2-(5z,8z,11z,14z-eicosatetraenoyl)-sn-glycero-3-phosphocholineMetforminPhe-glyOrnithineAzamethiphosDimethylallyl pyrophosphate5-pregnen-3.beta.-ol-20-one5-aminovaleric acidTepraloxydimL-glutarylcarnitineDextromethorphanD-ornithine3,7-Dimethyluric acid5-androsten-3.beta.,16.alpha.-diol-17-oneFumonisin b1Coniine6-methyl-2-thiouracilhydrocortisone 21-acetateMitraphyllineFumonisin b2N,n-dimethylguanosineDendrobinePseudopelletierineLeupeptinSulfasalazineVenlafaxineN.epsilon.-methyl-l-lysineTylosinGln-argAminoalbendazole sulfoneDoxepinAdenosine4-nitrophenolThyrotropin-releasing hormoneLanatoside cMexiletineCyclopiazonic acid4-imidazoleacrylic acidGuanidoacetic acidPterostilbeneGln-asnMatairesinolLobelanidineDibucaineCis-11,14-eicosadienoic acidPrallethrinDauricineDL-threonineBetonicinePeimineStearidonic acid5-MethylcytosineArgatroban2-hexenalSchisandrin b6-hydroxymelatoninIsoproterenol2-arachidonoyl-1-palmitoyl-sn-glycero-3-phosphoethanolamine4-hydroxyquinoline5.beta.-androsterone4-piperidinecarboxamidePC(16:0/16:0)SphingosineMinocyclineCalcimycin2'-hydroxy-4'-methoxyacetophenone1,3-diaminopropane2-amino-2-methyl-1,3-propanediolIsomenthone1-(1z-octadecenyl)-2-(4z,7z,10z,13z,16z,19z-docosahexaenoyl)-sn-glycero-3-phosphocholineTetrandrineN-phenyl-1-naphthylamineN-acetyl-d-galactosamineTelmisartan2-chloro-2',6'-diethylacetanilidePsychosineBuprenorphineAcetaminophen2-isopropoxyphenyl n-methylcarbamate5-methylcytosineL-kynurenineLinoleoylcarnitineMetconazoleCabergolinePhenylacetaldehydeAstragaloside iiTrehaloseBispyribacBufotalinGuanineMeperidineN,n-diethylcathinoneTrihydroxycholestanoic acidNivalenolRifampicinS-methyl-5'-thioadenosineUdp-n-acetylglucosamineLontrelDihydroberberine2-amino-1-phenylethanolIsosafroleEriodictyolSiduronParoxetineLupenoneFlunisolideL-propionylcarnitine1,3-DiaminopropaneAtrazine desisopropyl1-methyladenosineVasicineMyriocinNorcodeineDocosanamideTrans-ferulic acidTris(hydroxymethyl)aminomethaneAtrazineGyromitrin9-oxo-11-(3-pentyl-2-oxiranyl)-10e-undecenoic acid1,2-dioleoyl-sn-glycero-3-phospho-l-serineN-acetylputrescineN-acetylglutamineTrans-4-(aminomethyl)cyclohexanecarboxylic acidVeratramineZolmitriptan7-keto-8-aminopelargonic acid2-EthoxyethanolMilrinoneDimethachlonPravastatinGlycocholic acidZingeroneChenodeoxycholateGlycocholateRanolazine1-(1z-octadecenyl)-sn-glycero-3-phosphocholine1,2-dioctadecanoyl-sn-glycerolSimetrynDipropyl phthalateIndole-3-carboxaldehydeStachyoseAla-ProGlutethimide(+)-pseudoephedrineN-acetylneuraminic acid, 2,3-dehydro-2-deoxy-4-hydroxyphenylethanolEsculetinEddp2-amino-9h-pyrido[2,3-b]indole2'-Deoxyadenosine 5'-monophosphate (dAMP)DL-isoleucineZaleplonOxyacanthineHydroquinoneO-acetyl-l-serineWogoninGuanidinopropionic acidGuanidinoethyl sulfonateL-GlutamateAsiatic acidCafestol3-methylthiopropylamineGenisteinPyrimethanilDl-2,4-diaminobutyric acidTestosterone enanthateHinokiflavoneHis-Lys.alpha.-cyperonePymetrozin5.alpha.-androstan-3.beta.-ol1,2-dieicosenoyl-sn-glycero-3-phosphocholineLithocholylglycineHydrocortisone 21-hemisuccinateFarrerol7-methylguanine13-keto-9z,11e-octadecadienoic acidFosinoprilDihydromorphineO-anisidineErgocristine16-Hydroxypalmitic acidTaurineDiafenthiuronTrans-cinnamic acidTropacocaine.alpha.-L-Glu-GlyGeldanamycin2,4-diaminotolueneTrans-androsteroneL-ThreonineCyclopamineNelfinavir1-palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine1-stearoyl-2-linoleoyl-sn-glycerolAndrographolideAgmatineN-methyltryptamineNodakeninMyristoleic acidEpothilone bTrigonellineIsoliquiritigeninVinblastinePalmitoylserinolAngiotensin iiiAcetohexamidePhentermineSecbumetonN-Acetyl-D-glucosamineStylopineDanazolAjmalicinePentoxifyllinePrometon(-)-atropineForskolinL-aspartic acid5-methyl-2'-deoxycytidine7-Methylguanosine2-linoleoyl-1-palmitoyl-sn-glycero-3-phosphoethanolamineSolanidine base + o-hex-dhexConessine2-oleoyl-1-stearoyl-sn-glycero-3-phosphoserineDibenz(a,j)acridineArtemisininMedicarpinFenfluramine17alpha-hydroxyprogesteroneDL-glutamine.alpha.-ergocryptineN-tetracosenoyl-4-sphingenineOrlistatTriethanolamineN-acetylcadaverine1-Stearoyl-2-oleoyl-sn-glycerol 3-phosphocholine (SOPC)Oleoyl-l-carnitineO-phenylphenol1-stearoyl-2-docosahexaenoyl-sn-glycerolNeohesperidosePhenylalanine1-Myristoyl-sn-glycero-3-phosphocholineCholesterolFamotidineTestosteronePsoralidinSorbitane monostearate - polysorbate 60 in-source fragmentVernolateZeta-carotene19-hydroxytestosteroneHydroxyitraconazoleTrifloxystrobinMyosmine2-docosahexaenoyl-1-stearoyl-sn-glycero-3-phosphoserineBaccatin iiiEllipticineTryptaminePepstatin aMycophenolic acid.delta.-tocotrienol2-hydroxyestradiolSolanineMorphineN-acetylhistamineCreatineCytidine 5'-monophosphateChlorzoxazoneN-desbutylbupivacaineGamma-glutamylleucineBehenic acidNG,NG-dimethyl-L-arginine(ADMA)CytosineDihydrojasmonic acidPhenaceturic acid2,4-diamino-6-nitrotolueneAuranofinEthosuximideSumithrin4-hydroxy-l-phenylglycine2-Phenylbutyric acidGuanidinosuccinic acidErythromycinBisoprolol3-methylhistidineArachidonoylserinolSimazine1-oleoyl-sn-glycero-3-phosphoethanolamineSulfallateCarvedilolMetribuzinHirsuteine2-furanpropanoic acid, 3-carboxy-4-methyl-5-propyl-Bisphenol a diglycidyl ether4-amino-2,6-dinitrotolueneTrillinTralkoxydimNicotine5-aminoimidazole-4-carboxamideEthirimolDesmosterol1,4-d-xylobioseApigenin 7-glucoside1,2-dipalmitoleoyl-sn-glycero-3-phosphocholine2-pyrrolidinone, 1-methyl-Disopyramide1-Stearoyl-2-arachidonoyl-sn-glycerolSalanninDiacetoxyscirpenolIndinavirN-acetyl-.beta.-d-mannosaminePiperanineHarmalineZerumbone2-o-rhamnosylvitexinN2-Acetyl-L-ornithine(3r,7r,9s,10s,12s,13r,14s,17r)-17-((2r)-6,7-dihydroxy-6-methylheptan-2-yl)-10,13-dimethylhexadecahydro-1h-cyclopenta[a]phenanthrene-3,7,12-triolAcetamipridGln-thrFludarabineCdp-ethanolaminePhenanthridinePyridabenDimethylglycinePro-TrpDL-Glutamic acid.gamma.-l-glu-.epsilon.-l-lysN-acetyl-d-lactosamine4-cholestenoneChitobioseD-glucosaminic acid2-piperidone4-phenylpyridineHistidineLntConvallatoxinDiethylstilbestrolValidamycin aStearamideTyramineMetyraponePyraflufen-ethylTrinexapac-ethylNe-acetyllysineDeoxyadenosineSufentanyl1-stearoyl-2-oleoyl-sn-glycero-3-phosphoethanolamineEpigallocatechin gallateMelezitoseButyric acid, 4-[(4-chloro-o-tolyl)oxy]-GlycerophosphocholineSenkirkin3-methyladenineDiethyl phthalateDL-phenylalanineErgothioneineGlimepiride1-Aminocyclopropanecarboxylic acid(+)-.gamma.-tocopherolEthionamideNorharmaneRetrorsine n-oxide7-ethoxyresorufinPhencyclidineNizatidineMicrocystin lrCinobufotalin2-methoxyestradiolKynurenineCynarinDiethylcarbamazineCholecalciferol (Vitamin D3)4-nitroanisoleAlanineCordycepinPramoxineL-GlutamineNobiletinHis-LeuCholineSchizandrinN,n-diethyl-2-aminoethanolN-carboxyethyl-.gamma.-aminobutyric acidGlu-Lys1h-1,2,4-triazol-3-amineIsosakuranetinN-alpha-acetyl-l-lysine.delta.-hexalactone1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamineHomatropineO-succinyl-l-homoserineCis-7,10,13,16,19-docosapentaenoic acidAmetryneLsdN.epsilon.-acetyl-l-lysineBetulinGlufosinateDocetaxel1-deoxynojirimycinL-pipecolic acidPhosphorylcholine1,2-dioleoyl-sn-glycero-3-phosphoethanolamineChlormadinone acetate1-stearoyl-2-hydroxy-sn-glycero-3-phosphocholine3-dehydrocarnitine4,6-dioxoheptanoic acidFluphenazineN-nervonoyl-d-erythro-sphingosylphosphorylcholineSolasodineEchimidineN-acetyl-d-glucosaminePhyllanthinMarrubiinProcaine2'-deoxyinosine1-amino-1-cyclopentanecarboxylateHis-TyrNordihydrocapsaicinLeucine7-diethylamino-4-methylcoumarinEvodiamineCitalopram1-methyl-l-histidine1h-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione, 4,11-diethyl-4,9-dihydroxy-, (4s)-MifepristoneCurcuminPiperidine4-androstene-11.beta.,17.beta.-diol-3-oneN-acetylglucosamine6-benzylaminopurineGln-pheAtazanavir2-aminoadipic acidN-lauroyl-d-erythro-sphingosylphosphorylcholineArecaidineDethiobiotin10-nitrooleic acid.beta.-estradiol 3,17-dipropionatePhosphocholineBenz[a]anthraceneAndrostane-3,17-diol, (3.beta.,5.alpha.,17.beta.)-Linolenic acidMandelonitrileSulfathiazoleGln-AlaTebutam4,4'-thiodianilineAcenapthyleneLauric acid diethanolamide1-O-Octadecyl-sn-glyceryl-3-phosphorylcholineL-bunololPyocyaninProstaglandin h2RiboflavinErgocalciferol (Vitamin D2)Tributyl phosphate1-methylxanthine4-anisaldehydeDictamineEthylenediaminetetraacetic acidAspartameProstaglandin f1.alpha.StearoylcarnitineHeptanoic acid5-methoxytryptopholThalidomideCys-glyTriflumuronD-glucosamine 1-phosphateHydroxyflutamideTrichothecine2-octenoic acid, (e)-L-ProlineUreaDL-tryptophanAmpicillinHederagenin base + o-hexa-hexMyclobutanilIngenolFumagillinL-Aspartyl-L-phenylalanineTetraethylene glycol monomethyl etherDicyclohexylamineL-methionine1,2,3-benzenetriolPatchouli alcoholGinkgolide bL-AsparaginePhenyl phosphateThapsigarginN,n'-diacetylchitobiose1-arachidoyl-2-hydroxy-sn-glycero-3-phosphocholineGlu-ArgGlutaric acidDicyclomineEstriol1,2-di(4z,7z,10z,13z,16z,19z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamineIsoalantolactone3-phenylazopyridine-2,6-diamine20-hydroxycholesterol5.beta.-pregnane-3.alpha.,17.alpha.,20.alpha.-triolSchizandrin aN-octanoyl-l-homoserine lactoneMelamineAnastrozoleMiglitolDecanoyl-l-carnitine17alpha-ethynylestradiolFenpropidinall cis-(6,9,12)-Linolenic acid1-palmitoyl-2-hydroxy-sn-glycero-3-phosphoethanolamineL-homoarginineLinoleyl carnitine1,3-propanediolTriethylenetetramineThiaclopridButorphanolGuanosineRibothymidineTrimethoprim1-naphthaleneacetamide4-methylumbelliferyl .beta.-d-glucuronideCrotonosideCartapEthiofencarb sulfoneTillamPriminN,n-dimethylsphingosineGlu-AlaOctanoylcarnitine1,2-ditetradecanoyl-sn-glycero-3-phosphocholineG-guanidinobutyrateBuspironeDL-cysteineFormetanateCandesartan cilexetilImatinibArenobufaginBiliverdin1,2-dilauroyl-sn-glycerol4-hydroxybenzyl alcoholSipeimineLoganinCytochalasin a1-stearoyl-2-linoleoyl-sn-glycero-3-phosphocholineCytochalasin bPalmitoyl sphingomyelinMemantineFlumethasone pivalateSulfamethazinePenicillic acidFlonicamidCyproconazoleEnterodiolN-nitrosopyrrolidinePindololTrans-zeatin1-oleoyl-2-myristoyl-sn-glycero-3-phosphocholineJugloneCoproporphyrin iCymarin2-HydroxyadenineN-myristoylsphinganineBullatine gPuromycinN-oleoyl-d-erythro-sphingosylphosphorylcholineBeclomethasoneGestrinoneD-xylosePyroquilonDecanalEmetineDiethanolamineObacunoneKitasamycin1,2-di-(9z,12z,15z-octadecatrienoyl)-sn-glycero-3-phosphocholineSwainsonine.gamma.-aminobutyric acidCatalposideGlycochenodeoxycholateTomatidineGalanthamineCycloheximideL-TyrosineAcetylcarnitineDihydroconiferyl alcoholArgininosuccinic acidGlu-TrpPhorbol 12-myristate 13-acetate3,4-dihydroxy-l-phenylalanineDiboaPropentofyllineBenzothiazole, 2-methylmercapto-TrihexyphenidylTrachelanthineGuanabenz3-[(cholamidopropyl)dimethylammonio]-1-propanesulfonate1-(1z-octadecenyl)-2-(9z-octadecenoyl)-sn-glycero-3-phosphocholineCortexoloneSpermidineDisulfiram1-phenylethanol3-hydroxybenzoic acid2-[2-[19-acetamido-6-(3,4-dicarboxybutanoyloxy)-16,18-dihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic aci(-)-riboflavinPhe-proAsulamLopinavirSpectinomycinArctiinNorfloxacinUrocanic acid1-(1z-hexadecenyl)-sn-glycero-3-phosphocholinePropionylcarnitineDioctyl phthalateAmentoflavone2,3-dinor-8-isoprostaglandin-f2.alpha.Maprotiline3-methyl-2-buten-1-olPolygodialPerindoprilTrimethylamine n-oxideNeburonValsartanPheniramineGibberellin a4NefazodoneZearalenoneL-rhamnoseTetraethylene glycolLauroyl-l-carnitineIrisflorentin1-palmitoyl-2-oleoyl-sn-glycerol1-octadecyl lysophosphatidic acidBenzimidazolePerillaldehyde(-)-norephedrineAlprenololDimethyl sulfone5-methyl-5,6-dihydrouracilOcthilinoneOleandrinProsulfocarbCreatinineDexpanthenol.alpha.-ionone3-Aminobutanoic acidPyridoxineTrans-zeatin-ribosideN-.alpha.-acetyl-l-ornithineDiacetylL-tryptophanamideCyproheptadineTrimethylamineOxethazaine5-Aminopentanoic acidN-palmitoyl-d-sphingosineStachydrine.gamma.-undecalactone11-oxoandrosteronePalmitoleoyl ethanolamideHexaethylene glycolThiabendazole4-hydroxyphenethyl alcoholMalonyl-l-carnitine.beta.-d-glucoseTheobromineSteviolGinsenoside rh21-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-myo-inositol)BilirubinPropamocarbCinobufaginGamma-glu-gluUrobilin1,2-diarachidonoyl-sn-glycero-3-phosphocholineBetaineC16 lactosyl ceramide (d18:1/16:0)D-erythro-imidazolylglycerol phosphate3-methoxytyramine3'-hydroxyrepaglinideJasmonic acidGomisin cHesperetinD-Alanyl-D-alanine (D-Ala-D-Ala)2'-Deoxy-D-riboseEnrofloxacinCytidine3-methylxanthineBorrelidin3-methylglutarylcarnitineGlu-AsnTryptophan betaine3-amino-2,3-dihydrobenzoic acidAtorvastatin4-quinolinecarboxylate3,4,5-trimethoxycinnamic acidHomostachydrineL-Lysine3-hydroxybenzyl alcoholMorphine-3-glucuronideBupirimateDioxacarbN-(8z,11z,14z-eicosatrienoyl)ethanolamineAlfentanyl2-linoleoylglycerol4-methylbenzyl alcohol1-MethylhistidineHydrocortisoneCaffeateEconazoleGenipinUridine 5'-diphosphatePiperonyl sulfoxideHydrocotarninePalmitamidePhytolaccasaponin GStrychnineTrioxsalen(+)-6-aminopenicillanic acidCadusafosGlutathione, oxidizedMetoprololSphingomyelin (d18:1/18:0)Capsorubin1-o-hexadecyl-2-o-(4z,7z,10z,13z,16z,19z-docosahexaenoyl)-sn-glyceryl-3-phosphorylcholineMefenoxamHexanoyl-l-carnitineEsfenvalerateNudifloramideArachidonyl trifluoromethyl ketonePirimiphos-ethyl19-hydroxyandrost-4-ene-3,17-dione4-imidazoleacetic acid2-oleoyl-1-palmitoyl-sn-glycero-3-phosphocholineS-allyl-l-cysteineL-AspartateEthisterone5-acetylamino-6-amino-3-methyluracil5-methyluridineN-(phenylacetyl)-l-phenylalanineNaringenin3'-galactosyllactoseDigoxinEphedrineAla-ValDapsoneOrsellinic acidGlutaraldehydeGamma-l-glutamyl-l-glutamic acidL-SaccharopineXylometazolineN-FormylmethionineIndole-3-acetonitrileCytidine 5'-diphosphocholine1,2-dipentadecanoyl-sn-glycero-3-phosphoethanolaminePicrotinPodofiloxAnabasineNg,ng-dimethyl-l-arginineCastanospermineLeukotriene f4PentamidineFlindersineAlbiflorinN-desmethyltapentadolCaldine12-hydroxydodecanoic acid1,2-dimyristoyl-sn-glycero-3-phospho-l-serineGabapentinPodophyllotoxinRoridin a6'-sialyl-n-acetyllactosamine5.beta.-androstan-3.alpha.-ol-11,17-dioneEthyl glucuronide(3.beta.,5.alpha.)-4,4-dimethylcholesta-8,14,24-trien-3-olCitrininMethoxsalenBenthiavalicarb-isopropylHyperforinL-citrullineDaunorubicinResiniferatoxinLincomycinL-NorleucineDfplnnhCnicinDl-normetanephrineDL-valinePyridateNiacinamideCis-13-eicosenoic acidSuccinylcholineNordihydroguaiaretic acid7.alpha.-hydroxy-4-cholesten-3-oneOstholeBenzalkonium chloride (c12)Hc toxin13-oxoodeFlutamide2,4-dihydroxybenzophenoneLeukotriene c4MolinateN-AcetylmannosamineHexylamineN-(dodecanoyl)sphing-4-enine-1-phosphateEvodin3',5'-dimethoxy-3,5,7,4'-tetrahydroxyflavoneAcetolN-3-hydroxyoctanoyl-l-homoserine lactoneErythrodiolHarmineGossypolGinkgotoxin7-methylguanosine2,6-di-tert-butyl-4-hydroxymethylphenolAcetyleugenolPhytosphingosinePro-hypButyl oleateFenpropimorphPropranololD-sorbitolTyrosine4-hydroperoxy-2-nonenalResmethrinRhaponticin1-palmitoyl-sn-glycero-3-phosphocholineHypoxanthinePhenyllactic acid1-palmitoyl-2-myristoyl-sn-glycero-3-phosphocholineAmarogentinL-ArginineMethimazoleD-glutamineAdenosine 2'-monophosphatealpha-Linolenic acidAndrostan-3-ol-17-one 3-glucuronide3-Aminosalicylic acid1-oleoyl-sn-glycero-3-phosphocholineButylatePhenylethylamineDecursinolHypaconitineN-stearoylsphinganineErgosineScoulerineL-homocitrullineCytarabine1,2-dioleoyl-sn-glycerolL-CysteineN6,N6,N6-Trimethyl-L-lysineTomatidinPhenylacetyl-l-glutamineNicotinate d-ribonucleotideTropineGardenin bAdenineAmino-2-propanolEnoxacinGlu-IleN-acetyl-l-tyrosine2-arachidonoylglycerolCortisone3-hydroxyanthranilic acid1-Stearoyl-sn-glycerol 3-phosphocholine(LPC(18:0))Isobutyric acidDL-leucineWortmanninIsocarbamidEnalaprilatCocaineQuinacrine4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol1-naphthaldehydeGartanin(2e,4e)-hexa-2,4-dienoic acidOuabainCucurbitacin iCholic acid2'-O-methyladenosineHistidinolCucurbitacin eCarnosolCucurbitacin bBenzoylecgonineCellobiosePirimicarbMelibioseAnserineDL-3-Hydroxybutyric acidConiferyl aldehydeMethotrexatePantethineClothianidinCaffeineGeniposidic acidMaltotrioseAconineDichlormidAconitineSebacic acid4-methyl-1h-pyrazoleAcridine orangeThioridazine.beta.-sitosterolAntipyrineMethyldopaFlavine mononucleotideNicotinamideThreitolMetronidazoleTigecyclineTheophyllineIridinTestosterone decanoateVeratridineOleic acid methyl esterGambogic acidJacobineDimethyl phthalate2-docosahexaenoyl-1-palmitoyl-sn-glycero-3-phosphoethanolamine1-myristoyl-sn-glycero-3-phosphocholineDodemorphS-adenosyl-l-homocysteineAntheraxanthin3-aminohexanoic acidBetaine aldehydeO-acetyl-l-homoserineNisoldipine2`-methylacetanilideS(-)-cathinoneIsomaltoseFlavanole base + 2o, 2prenyl4-nitrosodiphenylamineEDTA7-amino-4-methylcoumarinL-palmitoylcarnitineProtriptylinePicloramN-octadecylamineIsopropalinAzatadineMefenamic acidN-Acetyl-L-alanine.gamma.-hexalactoneAcetylcholinePenitrem aAdenosine 5'-monophosphateCamptothecinFluorene2-oleoyl-1-palmitoyl-sn-glycero-3-phosphoserinePrednisolone 21-acetate2,6-dimethoxyphenolDibutyl phthalate3-acetylindoleSofalconeDiphenylamineSorbitane monopalmitate - polysorbate 40 in-source fragmentGlu-Thr2-aminophenolChlorothiazideArcaineTerbutalineIndole-3-acetamideFurmecyclox.beta.-Cyano-L-alanine10-deacetylbaccatin iii2-pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-n-methyl-1,5-diaminonaphthalene1-stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine3-(2-hydroxyethyl)indoleChrysosplenetinEstriol 16alpha-(beta-d-glucuronide)ValganciclovirDeoxycorticosterone acetateIndole-3-acetaldehydeLathosterolCidofovirMaltoseL-hydroxyarginineIndaloneBufalinMethyl jasmonateHistamine1-methylhistamineOrcinolPicrotoxinin(r)-butyrylcarnitineOphiobolin aMethionine sulfoxidePterineN,n,n-trimethyllysineOxycodone3-methyl-l-histidineOxazepam(-)-(3s)-3-hydroxyquinineN-methyl-l-alanineSenecionineByakangelicolLappaconitineBromodiphenhydramine1-heptadecanoyl-sn-glycero-3-phosphocholine1-docosahexaenoyl-2-stearoyl-sn-glycero-3-phosphocholine1-acetylimidazole5alpha-pregnan-3,20-dione3,3'-dimethyl-4,4'-diaminodiphenylmethanePyrrolidineQuinolinateAnemoninDiallyl sulfideDiethyltoluamideAlbizziinDL-serineVindesineL-canavanineNicotinate1,2-di-(9z-tetradecenoyl)-sn-glycero-3-phosphocholineTerfenadinePhosphocreatineImazethapyrN-acetylhistidineAnisomycinD-fructose 6-phosphate6,7-dimethylesculetin2-methylamino-1-(3,4-methylenedioxyphenyl)propan-1-oneHerbimycin a2-hydroxy-4-methoxybenzophenone5-hydroxyvalproic acidDaidzeinDL-Methionine sulfoxidefalseEarly microbial and metabolic remodeling of the neovagina after laparoscopic peritoneal vaginoplasty in MRKH syndromeThis integrated multi-omics study investigated early microbial succession and metabolic remodeling of the neovagina in patients with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome after laparoscopic peritoneal vaginoplasty. Preoperative vestibular dimple samples (PRE) and postoperative day 14 neovaginal secretion samples (P14D) were collected and analyzed using untargeted UHPLC-Q-TOF metabolomics, 16S rRNA gene sequencing, and fluorescence quantitative PCR for sexually transmitted infection detection. The metabolomics component aims to characterize biochemical changes associated with early neovaginal epithelialization and to explore microbiota-metabolite associations during postoperative microenvironmental remodeling.2026-06-302026-06-24MTBLS14845HMDB0028819HMDB0062770HMDB0002780;C06562HMDB0012097HMDB0005780HMDB0011460HMDB0011339HMDB0011352HMDB0137236;C10494HMDB0010407HMDB0005779HMDB0001213;C11437HMDB0012108HMDB0062325HMDB0011729HMDB0003099;C16359HMDB0007982HMDB0007973HMDB0010381HMDB0010384;C04230HMDB0011130HMDB0008994HMDB0008038HMDB0002107;C01606HMDB0012330HMDB0007865HMDB0010159HMDB0010565HMDB0010564HMDB0012378HMDB0002712;C07326HMDB0013633;C14807HMDB0004702HMDB0006294;C18218HMDB0000374;C01176HMDB0000403HMDB0001864;C00902HMDB0008928HMDB0011723HMDB0010163HMDB0000225;C00322HMDB0012141;C04272HMDB0005998;C14748HMDB0004026;C05485HMDB0001032;C04555HMDB0000387HMDB0000428HMDB0000754HMDB0001954;C20793HMDB0001490;C05594HMDB0003332HMDB0000019;C00141HMDB0001955HMDB0000609HMDB0001856;C00230HMDB0000423;C10447HMDB0062295HMDB0014378;C02518HMDB0013848HMDB0001101;C02519HMDB0001858;C01468HMDB0001232;C00870HMDB0000017;C00847HMDB0003192;C04051HMDB0006248;C03740HMDB0010217HMDB0012843;C06103HMDB0014797HMDB0000060;C00164HMDB0000034;C00147HMDB0001003;C00224HMDB0000303;C00398HMDB0000462;C01551HMDB0003345;C00267HMDB0001586;C00103HMDB0000208;C00026HMDB0006344;C04148HMDB0015274;C06819HMDB0002829;C11135HMDB0030837;C10428HMDB0001043;C00219HMDB0035782;C08617HMDB0000168;C00152HMDB0000191;C00049HMDB0035473HMDB0000784;C08261HMDB0000011;C01089HMDB0030094;C08619HMDB0033826;C14693HMDB0000511;C01571HMDB0000055;C06422HMDB0000653;C18043HMDB0030282;C06528HMDB0002183;C06429HMDB0003229;C08362HMDB0000072;C00417HMDB0006331;C02480HMDB0000570;C05770HMDB0031340;C02824HMDB0001176;C00128HMDB0001321;C00279HMDB0062538;C00095HMDB0000625;C00257HMDB0000150;C00198HMDB0001109;C06156HMDB0000186;C00243HMDB0000163;C00208HMDB0000169;C00159HMDB0003848;C04520HMDB0003411;C00763HMDB0004136;C16884HMDB0011740;C19636HMDB0000626;C04483HMDB0000071;C05512HMDB0001192;C04058HMDB0015468;C06955HMDB0000079;C00906HMDB0000076;C00429HMDB0001882;C00184HMDB0000779/HMDB0014712;C01479HMDB0000008;C05984HMDB0000742;C05330HMDB0000623;C02678HMDB0000638;C02679HMDB0041886;C11720HMDB0002068;C08316HMDB0004483;C11133HMDB0131282HMDB0061650;C19418HMDB0130571;C09734HMDB0005808;C00858HMDB0015118;C07805HMDB0004089;C05653HMDB0001076;C01094HMDB0001049;C00669HMDB0034367HMDB0004062;C05585HMDB0028799HMDB0028823HMDB0029156HMDB0028827HMDB0028832HMDB0000148;C00025HMDB0000641;C00064HMDB0000139/HMDB0031818;C00258HMDB0000086;C00670HMDB0000138;C01921HMDB0000631;C05464HMDB0002259HMDB0000672;C19615HMDB0000714;C01586HMDB0000133;C00387HMDB0000665;C03264HMDB0000350HMDB0029737;C08493HMDB0003320;C19837HMDB0000197;C00954HMDB0000671;C02043HMDB0000682HMDB0000195;C00294HMDB0000175;C00130HMDB0015163;C07469HMDB0000730HMDB0000689HMDB0015303;C01822HMDB0000695;C00233HMDB0030392HMDB0000715;C01717HMDB0000194;C01262HMDB0001851;C00532HMDB0000033;C00386HMDB0003349;C00337HMDB0062489;C01019HMDB0001265;C02985HMDB0003466;C01040HMDB0002205;C16511HMDB0000687;C00123HMDB0011756;C02710HMDB0000156;C00149HMDB0000267;C01879HMDB0000849;C00507HMDB0000187/HMDB0062263;C00065HMDB0000943/HMDB0062620;C01620HMDB0014736;C07063HMDB0001251;C01724HMDB0001085;C02165HMDB0003080;C05951HMDB0000720HMDB0002003;C08320HMDB0000673;C01595HMDB0000761;C03990HMDB0001198;C02166HMDB0002928HMDB0001296;C02052HMDB0001262;C01835HMDB0030017;C00828HMDB0015446;C07618HMDB0061859;C16995HMDB0000202;C02170HMDB0000227/HMDB0059629;C00418HMDB0015335;C11195HMDB0041933;C09226HMDB0000211;C00137HMDB0000806;C06424HMDB0001348;C00550HMDB0001367;C04256HMDB0001129;C00645HMDB0000766HMDB0000812;C01042HMDB0001138;C00624HMDB0011745;C02712HMDB0000230;C00270HMDB0002064;C02714HMDB0002931HMDB0004949HMDB0003556;C01674HMDB0005923HMDB0014629HMDB0014745;C07250HMDB0002368;C08323HMDB0014760;C07264HMDB0015595HMDB0000827;C01530HMDB0000207;C00712HMDB0014906;C07789HMDB0000788;C01103HMDB0059933;C06677HMDB0000220;C00249HMDB0000210;C00864HMDB0000826;C16537HMDB0000228;C00146HMDB0000159;C00079HMDB0000205;C00166HMDB0036634;C01604HMDB0000263;C00074HMDB0001565;C00588HMDB0138206HMDB0000245;C00931HMDB0060382;C18044HMDB0001830;C00410HMDB0060933HMDB0002982;C00959HMDB0001220;C00584HMDB0000767;C02067HMDB0034050;C10523HMDB0001167;C00546HMDB0000243;C00022HMDB0000232;C03722HMDB0003213;C00492HMDB0014351;C06539HMDB0133830HMDB0133823;C10176HMDB0034297;C08365HMDB0000840;C07588HMDB0000187;C00065HMDB0000114;C01233HMDB0000254;C00042HMDB0002085;C10833HMDB0015002;C01375HMDB0000951;C05465HMDB0000036;C05122HMDB0002580;C03642HMDB0015101;C07710HMDB0000234;C00535HMDB0000167;C00188HMDB0000262;C00178HMDB0000933;C16308HMDB0001160HMDB0000302;C00052HMDB0000290;C00043HMDB0000300;C00106HMDB0000289;C00366HMDB0000296;C00299HMDB0000288;C00105HMDB0000301;C00785HMDB0000892;C00803HMDB0000484;C06672HMDB0014681;C07204HMDB0000044;C00072HMDB0000292;C00385HMDB0000299;C01762HMDB0001554;C00655HMDB0002917;C00379HMDB0014543HMDB0000645;C00446HMDB0000729HMDB0002520;C02979HMDB0000710;C00989HMDB0038361;C12136HMDB0013692;C18167HMDB0035140;C06082HMDB0009036HMDB0012183HMDB0000452;C02356HMDB0000992;C19569HMDB0036458;C01234HMDB0010405HMDB0000001;C01152HMDB0012138;C11714HMDB0011506HMDB0011503HMDB0012380HMDB0008039HMDB0030571HMDB0124831;C02814HMDB0001857HMDB0011103;C16356HMDB0006485;C03204HMDB0060906HMDB0004031;C05498HMDB0112194HMDB0000335;C05300HMDB0062612HMDB0011747;C03557HMDB0009003HMDB0001353;C01216HMDB0001031;C00673HMDB0001975HMDB0061112HMDB0000407HMDB0000624;C03264HMDB0000402;C02504HMDB0030524;C14437HMDB0003745;C03576HMDB0000354HMDB0002340;C07215HMDB0000422HMDB0013211HMDB0000397;C00196HMDB0004811;C02625HMDB0004812;C20450HMDB0013676;C21298HMDB0003224;C01801HMDB0000905;C00360HMDB0006555;C06196HMDB0004326;C04779HMDB0029646;C10680HMDB0000016;C03205HMDB0002199;C01744HMDB0240217HMDB0000955;C10470HMDB0000357;C01089HMDB0061656HMDB0000440;C05593HMDB0000021;C02515HMDB0012156;C04411HMDB0000491;C03465HMDB0000764;C05629HMDB0000181;C00355HMDB0029661;C10675HMDB0059965;C16700HMDB0001866;C05580HMDB0001336;C01161HMDB0032616;C00482HMDB0140470HMDB0038925HMDB0004815HMDB0011718;C00633HMDB0002035;C00811HMDB0000873;C06730HMDB0000543;C21793HMDB0013636;C00113HMDB0135607;C14232HMDB0136142HMDB0014389;C07138HMDB0060396;C16633HMDB0000472;C00643HMDB0000763;C05635HMDB0000450;C16741HMDB0000469;C03088HMDB0001855HMDB0002004;C08309HMDB0011725;C16199HMDB0032950;C09001HMDB0062657HMDB0001517;C04677HMDB0060412;C16614HMDB0001537HMDB0141530;C14137HMDB0002658;C01020HMDB0000530HMDB0015167;C02380HMDB0059622;C03081HMDB0141531;C11264HMDB0000897;C02242HMDB0011107;C16355HMDB0030701HMDB0059801;C11430HMDB0062179;C04663HMDB0001494;C00227HMDB0001890;C06809HMDB0001879;C01405HMDB0000448;C06104HMDB0028695HMDB0028700HMDB0006254;C16677HMDB0006285HMDB0001209;C00499HMDB0005843;C19317HMDB0001867;D06890HMDB0001147;C00872HMDB0029683;C10759HMDB0000053;C00280HMDB0002759HMDB0003012;C00292HMDB0002124;C01477HMDB0002212;C06425HMDB0005006;C06834HMDB0041833;C00813HMDB0030636HMDB0001870;C00180HMDB0015605;C12864HMDB0013679;C00758HMDB0000151;C00951HMDB0003134;C05552HMDB0002114;C17743HMDB0041842;C08299HMDB0000039;C00246HMDB0003501;C01481HMDB0001847;C07481HMDB0141765HMDB0000535/HMDB0061883;C01585HMDB0000482/HMDB0062511;C06423HMDB0000828;C00438HMDB0014809;C06881HMDB0240226;C07778HMDB0000518;C02528HMDB0000619;C00695HMDB0012199;C00251HMDB0036619;C10028HMDB0014513;C06909HMDB0015535;C01675HMDB0036576;C03440HMDB0002226;C16527HMDB0240219;C21944HMDB0000634;C02226HMDB0000094;C00158HMDB0060464;C16577HMDB0006709;C00399HMDB0141782;C02666HMDB0001547;C02140HMDB0000064;C00300HMDB0033960;C16942HMDB0000099;C02291HMDB0002757;C00506HMDB0000731;C05824HMDB0000089;C00475HMDB0033704;C00124HMDB0062473;C00936HMDB0003391;C00197HMDB0001310;C01401HMDB0001151;C01487HMDB0000539;C00878HMDB0000568;C01904HMDB0006483;C00402HMDB0000277;C06124HMDB0000349HMDB0062538;C00095/C05003/C10906HMDB0000639;C00879HMDB0000663;C00818HMDB0001254;C00352HMDB0000127;C00191HMDB0003423;C00064HMDB0000765;C00392HMDB0001530;C00644HMDB0001078;C00275HMDB0001498;C01245HMDB0003374;C00515HMDB0000283;C00121/C21057HMDB0001548;C00199HMDB0003418;C00795HMDB0001264;C05422HMDB0033801;C17742HMDB0000101;C00559HMDB0003581;C01909HMDB0015251;C06949HMDB0001473;C00111HMDB0003701;C03114HMDB0000318;C05576HMDB0060475;C00025HMDB0006050HMDB0000158;C00082HMDB0133489;C05584HMDB0014979;C06967HMDB0059915HMDB0000073;C03758HMDB0000107;C01697HMDB0001999;C06428HMDB0002899;C10788HMDB0006101;C18165HMDB0032280HMDB0030820;C09264HMDB0000145;C00468HMDB0031233HMDB0014887;C06991HMDB0094711;C16322HMDB0015326;C07001HMDB0000121;C00504HMDB0000660;C01496HMDB0000134;C00122HMDB0005826;C01235HMDB0029521;C10044HMDB0005807;C01424HMDB0011738HMDB0011737;C05282HMDB0015178;C07661HMDB0015371;C07020HMDB0003217;C06563HMDB0000152;C00628HMDB0001285;C05847HMDB0004486;C00353HMDB0028790HMDB0028809HMDB0003764HMDB0001514;C00329HMDB0000122;C00031HMDB0000661;C00489HMDB0000125;C02471HMDB0011733;C02037HMDB0000759;C02155HMDB0001051;C02154HMDB0001112;C00661HMDB0000131;C00116HMDB0000126;C00093HMDB0000123;C00037HMDB0000115;C00160HMDB0000119;C00048HMDB0013222;C03065HMDB0001397;C00144HMDB0030311;C06538HMDB0005801;C05903HMDB0000273;C00214HMDB0028894HMDB0000130;C00544HMDB0011719HMDB0000755;C03672HMDB0000965;C00519HMDB0001925;C01588HMDB0000012;C00526HMDB0040292;C11110HMDB0011753;C19911HMDB0034376;C09269HMDB0000738;C00463HMDB0002096;C11284HMDB0060484;C00331HMDB0001873;C02632HMDB0000193;C00311HMDB0030871;C10070HMDB0002923;C00252HMDB0001347;C00129HMDB0032797;C08491HMDB0000190;C00186HMDB0059655;C03196HMDB0000161;C00041HMDB0000517;C00062HMDB0060179;C00606HMDB0000192;C00491HMDB0062697;C00051HMDB0000670;C01924HMDB0000679;C02427HMDB0000719;C00263HMDB0004224;C05933HMDB0011632;C01507HMDB0000172;C00407HMDB0000162;C00148HMDB0034365;C01047HMDB0000943;C01620HMDB0000883;C00183HMDB0000740;C07064HMDB0001929;C07660HMDB0041920HMDB0005800;C01514HMDB0003405;C00047HMDB0031518;C00711HMDB0000176;C01384HMDB0000691;C00383HMDB0001389;C01598HMDB0000749;C01732HMDB0240280;C11145HMDB0240266HMDB0059629;C00418HMDB0061039HMDB0013247HMDB0000858HMDB0000512;C03519HMDB0000866;C01657HMDB0000215;C00140HMDB0006029HMDB0001238;C00978HMDB0062723;C03622HMDB0033835;C11155HMDB0000206;C02727HMDB0002099;C08434HMDB0001132;C01185HMDB0003269;C05380HMDB0014537;C07267HMDB0001904HMDB0000847;C01601HMDB0015192;C06687HMDB0011185;C12147HMDB0000224;C00346HMDB0006049;C06501HMDB0012209;C06608HMDB0061737HMDB0033375HMDB0000226;C00295HMDB0015126;C07356HMDB0000786;C07599HMDB0128505;C10273HMDB0135648;C05608HMDB0003654;C02646HMDB0014427;C07395HMDB0004231;C05944HMDB0059586;C18142HMDB0004586;C11924HMDB0014928;C07706HMDB0011177HMDB0060014HMDB0014950;C07440HMDB0000779;C01479HMDB0003306;C00774HMDB0137958;C06356HMDB0125090HMDB0001511;C02305HMDB0014966;C06454HMDB0000973;C00009HMDB0000272;C01005HMDB0002243;C10164HMDB0000857;C02656HMDB0015264;C07675HMDB0030564;C10275HMDB0005022;C01844HMDB0004620HMDB0015537;C07373HMDB0000237;C00163HMDB0005102;C06438HMDB0002664;C06439HMDB0001483;C02314HMDB0001335;C01312HMDB0001366;C15587HMDB0001491;C00018HMDB0000957;C00090HMDB0000842;C06325HMDB0003072;C00296HMDB0003364;C00472HMDB0061005HMDB0000253;C03582HMDB0001358;C00376HMDB0000305;C19962HMDB0032876;C10401HMDB0005031HMDB0029415;C03727HMDB0001066;C03451HMDB0029723;C12283HMDB0034170;C06202HMDB0034344;C01752HMDB0000792;C08277HMDB0014562HMDB0003966;C05335HMDB0000238;C00835HMDB0000259;C00780HMDB0003070;C00493HMDB0030579;C17412HMDB0013070;C02325HMDB0014632;C07309HMDB0000893;C08278HMDB0001259;C00232HMDB0000258;C00089HMDB0000956;C00898HMDB0000251;C00245HMDB0060619;C21518HMDB0002428;C06337HMDB0000872HMDB0000268;C05476HMDB0002666;C01081HMDB0003252;C05963HMDB0060597HMDB0001568HMDB0001470;C08279HMDB0000077;C01227HMDB0000910;C17076HMDB0014118HMDB0001202;C00239HMDB0000888HMDB0000286;C00029HMDB0003555;C02059HMDB0059883;C12286HMDB0060245;C02512HMDB0000852;C01753HMDB0003869;C21730HMDB0034221;C08257HMDB0000244;C00255HMDB0029581HMDB0002013HMDB0011262HMDB0011253HMDB0011243HMDB0013122HMDB0008727HMDB0003331;C02494HMDB0000898;C05127HMDB0000001/HMDB0000479;C01152HMDB0010738;C16358HMDB0010379HMDB0013409HMDB0011149HMDB0011144HMDB0008097HMDB0002815HMDB0007991HMDB0007102HMDB0010382HMDB0032619;C07112HMDB0009815HMDB0012383HMDB0007098/HMDB0007099/HMDB0007100/HMDB0007101/HMDB0007103/HMDB0007108/HMDB0007112/HMDB0007131/HMDB0007132/HMDB0007156/HMDB0007166/HMDB0007170/HMDB0007223/HMDB0007224/HMDB0007248/HMDB0007257/HMDB0007398;C00165HMDB0008057HMDB0007179HMDB0007161HMDB0008993HMDB0000564/HMDB0007878/HMDB0007879/HMDB0007880/HMDB0007882/HMDB0007884/HMDB0007886/HMDB0007887/HMDB0007897/HMDB0007898/HMDB0007911/HMDB0007912/HMDB0007913/HMDB0007914/HMDB0007936/HMDB0007937/HMDB0007938/HMDB0007939/HMDB0007940/HMDB0007958/HMDB0007959/HMDB0007960/HMDB0007961/HMDB0007964/HMDB0007966/HMDB0007967/HMDB0007981/HMDB0007982/HMDB0007983/HMDB0007984/HMDB0007985/HMDB0008002/HMDB0008003/HMDB0008004/HMDB0008005/HMDB0008028/HMDB0008029/HMDB0008065/HMDB0008066/HMDB0008067/HMDB0008068/HMDB0008069/HMDB0008070/HMDB0008071/HMDB0008091/HMDB0008092/HMDB0008119/HMDB0008120/HMDB0008121/HMDB0008126/HMDB0008129/HMDB0008145/HMDB0008147/HMDB0008182/HMDB0008183/HMDB0008186/HMDB0008191/HMDB0008192/HMDB0008230/HMDB0008231/HMDB0008232/HMDB0008233/HMDB0008269/HMDB0008270/HMDB0008271/HMDB0008272/HMDB0008274/HMDB0008304/HMDB0008306/HMDB0008308/HMDB0008309/HMDB0008312/HMDB0008317/HMDB0008322/HMDB0008323/HMDB0008324/HMDB0008375/HMDB0008377/HMDB0008379/HMDB0008400/HMDB0008401/HMDB0008402/HMDB0008409/HMDB0008410/HMDB0008413/HMDB0008414/HMDB0008415/HMDB0008416/HMDB0008426/HMDB0008427/HMDB0008428/HMDB0008429/HMDB0008431/HMDB0008444/HMDB0008507/HMDB0008508/HMDB0008509/HMDB0008510/HMDB0008514/HMDB0008515/HMDB0008516/HMDB0008522/HMDB0008536/HMDB0008537/HMDB0008538/HMDB0008539/HMDB0008540/HMDB0008541/HMDB0008542/HMDB0008543/HMDB0008606/HMDB0008607/HMDB0008608/HMDB0008609/HMDB0008610/HMDB0008611/HMDB0008612/HMDB0008614/HMDB0008615/HMDB0008655/HMDB0008657/HMDB0008658/HMDB0008659/HMDB0008660/HMDB0008661/HMDB0008662/HMDB0008663/HMDB0008664/HMDB0008665/HMDB0008668/HMDB0008669/HMDB0008670/HMDB0008671/HMDB0008672/HMDB0008673/HMDB0008674/HMDB0008676/HMDB0008681/HMDB0008682/HMDB0008683/HMDB0008684/HMDB0008686/HMDB0008688/HMDB0008690/HMDB0008691/HMDB0008692/HMDB0008697/HMDB0008698/HMDB0008699/HMDB0008700/HMDB0008702/HMDB0008703/HMDB0008704/HMDB0008706/HMDB0008707/HMDB0008730/HMDB0008731/HMDB0008732/HMDB0008733/HMDB0008734/HMDB0008735/HMDB0008736/HMDB0008737/HMDB0008738/HMDB0008745/HMDB0008746/HMDB0008747/HMDB0008748/HMDB0008749/HMDB0008750/HMDB0008751/HMDB0008752/HMDB0008754/HMDB0008758/HMDB0008761/HMDB0008762/HMDB0008766/HMDB0008768/HMDB0008770/HMDB0008773/HMDB0008774/HMDB0008775/HMDB0008791/HMDB0008792/HMDB0008793/HMDB0008795/HMDB0008796/HMDB0008798/HMDB0008799/HMDB0008800;C00157HMDB0007900HMDB0008206HMDB0009705HMDB0008443HMDB0008308HMDB0007158HMDB0062690HMDB0012390HMDB0007218HMDB0008002HMDB0007866HMDB0000002;C00986HMDB0002059;C08317HMDB0004668HMDB0001926;C07534HMDB0034699HMDB0001065;C02735HMDB0000510;C00956HMDB0008937HMDB0032855;C21712HMDB0008946HMDB0031213;C14687HMDB0011538HMDB0000405;C05302HMDB0007972HMDB0012357HMDB0240212HMDB0011749;C10482HMDB0032048HMDB0034158;C10787HMDB0013751;C02502HMDB0031654HMDB0029168HMDB0001972HMDB0012154;C02636HMDB0062735HMDB0030124;C01390HMDB0000479;C01152HMDB0000552HMDB0006599HMDB0003193;C11134HMDB0032012;C06317HMDB0011724;C17467HMDB0004284;C06044HMDB0003355;C00431HMDB0001896HMDB0002894;C02376HMDB0000884HMDB0005830HMDB0000490;C04373HMDB0006584HMDB0001107HMDB0001993;C05455HMDB0013623HMDB0001859;C06804HMDB0000895;C01996HMDB0000532;C02055HMDB0000050;C00212HMDB0000045;C00020HMDB0001432;C00179HMDB0014940;C08005HMDB0003073;C06426HMDB0001388;C06427HMDB0030832;C10018HMDB0015348;C08159HMDB0004484;C11136HMDB0000493;C12525HMDB0001036;C15848HMDB0001123;C00108HMDB0037340;C04608HMDB0013650HMDB0015205HMDB0015130;C06836HMDB0013609;C06842HMDB0000043;C00719HMDB0001252;C00576HMDB0000054;C00486HMDB0001008;C00500HMDB0014750;C06852HMDB0032737;C14348HMDB0015367HMDB0060665;C09084HMDB0014633;C06861HMDB0014749;C06863HMDB0014393;C08187HMDB0015267;C06875HMDB0000876;C05443HMDB0000067;C00187HMDB0000097;C00114HMDB0035159HMDB0006528;C16513HMDB0005038;C07572HMDB0000643;C05769HMDB0000562;C00791HMDB0002269;C10443HMDB0031404;C00571HMDB0015122;C02961HMDB0001413;C00307HMDB0000095;C00055HMDB0000630;C00380HMDB0003459;C00993HMDB0060254;C00181HMDB0003312;C10208HMDB0014395;C07666HMDB0014832;C01907HMDB0062631HMDB0002719;C01802HMDB0000579HMDB0003407;C00741HMDB0036491;C08370HMDB0033733;C15770HMDB0014668;C07879HMDB0033244;C14214HMDB0004437;C06772HMDB0014849;C07968HMDB0001917;C06956HMDB0033524HMDB0033601HMDB0015203;C06957HMDB0004983;C11142HMDB0001120;C00235HMDB0000092;C01026HMDB0002362;C03283HMDB0000011/HMDB0000357;C01089HMDB0030396;C00078HMDB0015378;C11231HMDB0015109;C00284HMDB0003153;C09731HMDB0000900;C05441HMDB0003045;C05570HMDB0014344;C01912HMDB0000153;C05141HMDB0006766;C05504HMDB0010325HMDB0005030;C06999HMDB0029532HMDB0001520;C00061HMDB0014801HMDB0014326;C07005HMDB0014761;C07010HMDB0014642;C07653HMDB0014635;C07016HMDB0034702;C19241HMDB0034703;C19242HMDB0003464;C01035HMDB0011171HMDB0034942;C11673HMDB0014367;C07669HMDB0028791HMDB0028804HMDB0028805HMDB0028807HMDB0028813HMDB0028814HMDB0028822HMDB0004207HMDB0028830HMDB0029599;C12518HMDB0003337;C00127HMDB0000637;C05466HMDB0040723;C07667HMDB0000132;C00242HMDB0034540HMDB0000756HMDB0060263;C00388HMDB0000177;C00135HMDB0002434;C00530HMDB0061035HMDB0000157;C00262HMDB0014757HMDB0014369;C07051HMDB0001190;C00637HMDB0029739;C02693HMDB0006524;C02938HMDB0015197;C07056HMDB0030773;C03840HMDB0000706HMDB0015341;C07914HMDB0062496;C00318HMDB0000904;C00327HMDB0013130HMDB0000182;C00047HMDB0000696;C00073HMDB0000222;C02990HMDB0000070/HMDB0000716;C00408HMDB0062514HMDB0000279/HMDB0062698;C00449HMDB0001170;C01189HMDB0002250HMDB0028933;C11332HMDB0006469HMDB0006461HMDB0000698;C15557HMDB0006566HMDB0015539;C12871HMDB0000802;C00715HMDB0062592HMDB0012254HMDB0014922;C02168HMDB0041922;C08737HMDB0011730;C08243HMDB0000048;C05402HMDB0014597;C07128HMDB0015052;C07203HMDB0014972;C07652HMDB0014634;C07708HMDB0015152;C07225HMDB0014440;C01516HMDB0041936;C16643HMDB0015159;C20380HMDB0002000;C08322HMDB0005066HMDB0003357;C00437HMDB0013625HMDB0002372HMDB0006583;C00611HMDB0013253;C05135HMDB0014748;C02997HMDB0002201HMDB0060725HMDB0001015;C03145HMDB0012096HMDB0011759HMDB0012107HMDB0012101HMDB0011761HMDB0004953HMDB0033971HMDB0004824HMDB0013645HMDB0002038;C02728HMDB0001325;C03793HMDB0015280;C07256HMDB0014365;C07257HMDB0001539;C03626HMDB0001406;C00153HMDB0001488;C00253HMDB0029540;C10112HMDB0015092HMDB0012897;C20157HMDB0004193;C05842HMDB0094680HMDB0000791HMDB0002117;C19670HMDB0005065HMDB0000214;C01602HMDB0030172;C09598HMDB0061712HMDB0003828;C12661HMDB0014853;C07415HMDB0000564;C00157HMDB0014876;C07420HMDB0015557HMDB0006236;C00601HMDB0012275;C05332HMDB0034636HMDB0004610;C12144HMDB0002322;C09529HMDB0033874HMDB0015310;C08411HMDB0006695HMDB0000269;C00836HMDB0014859;C07375HMDB0000648;C01747HMDB0031641HMDB0015235;C07339HMDB0014388HMDB0014646;C07240HMDB0000939;C00021HMDB0034323;C16759HMDB0001173;C00170HMDB0006565HMDB0042013HMDB0033696HMDB0035282;C10822HMDB0029887HMDB0015055;C02078HMDB0001348/HMDB0010168/HMDB0010169/HMDB0011698/HMDB0011699/HMDB0012084/HMDB0012085/HMDB0012087/HMDB0012088/HMDB0012089/HMDB0012090/HMDB0012091/HMDB0012092/HMDB0012093/HMDB0012094/HMDB0012095/HMDB0012096/HMDB0012100/HMDB0012101/HMDB0012102/HMDB0012103/HMDB0012104/HMDB0012105/HMDB0012107/HMDB0013461/HMDB0013462/HMDB0013463/HMDB0013464/HMDB0013465/HMDB0013466/HMDB0013467/HMDB0013468/HMDB0013469;C00550HMDB0000252;C00319HMDB0004827;C10172HMDB0003553;C01613HMDB0034146;C13846HMDB0006547;C16300HMDB0011614;C06522HMDB0014846;C08022HMDB0015522;C19530HMDB0014486;C07463HMDB0094708HMDB0062236HMDB0002825;C07480HMDB0014817HMDB0060080;C03958HMDB0012204;C00371HMDB0000975;C01083HMDB0032538;C06771HMDB0000875;C01004HMDB0014520;C07171HMDB0014583;C01965HMDB0000906;C00565HMDB0000925;C01104HMDB0061115;C09213HMDB0034108;C01457HMDB0000306;C00483HMDB0000294;C00086HMDB0015548HMDB0014323HMDB0014454HMDB0036927HMDB0032590;C17497HMDB0000516;C00221HMDB0000453HMDB0062769;C06593HMDB0000112;C00334HMDB0003843HMDB0038311;C08571HMDB0014568;C02046HMDB0001942;C16719HMDB0060618;C02954HMDB0001943;C02765HMDB0001023;C11455HMDB0002180HMDB0062225;C03969HMDB0010390HMDB0060325;C14090HMDB0032710;C18533HMDB0007965HMDB0008927HMDB0093027HMDB0009059HMDB0008889HMDB0013674;C01108HMDB0062737HMDB0003955;C05290HMDB0060089;C05294HMDB0060510;C11173HMDB0033141;C19186HMDB0032628;C09764HMDB0004666;C13856HMDB0010167HMDB0015497;C14285HMDB0000338;C05301HMDB0000329HMDB0014542HMDB0031179;C11037HMDB0041253HMDB0060362;C16396HMDB0041799;C14401HMDB0003447;C00955HMDB0014511;C10926HMDB0001476;C00632HMDB0002466;C00587HMDB0059712;C03351HMDB0000022;C05587HMDB0011600;C00913HMDB0001886;C16357HMDB0015506;C07429HMDB0002511HMDB0001982;C16360HMDB0060979HMDB0041809;C19574HMDB0034179HMDB0060339;C18075HMDB0029686;C10761HMDB0000921;C00599HMDB0060287HMDB0002024;C02835HMDB0015344;C07837HMDB0041609;C06757HMDB0033123;C11481HMDB0000635HMDB0004400;C16366HMDB0000352;C05139HMDB0003818;C04295HMDB0013898;C16650HMDB0000253;C01953HMDB0006031;C14552HMDB0003759;C03681HMDB0039238;C11263HMDB0004081;C05643HMDB0030818;C09311HMDB0001107;C20674HMDB0001944;C06946HMDB0014558;C06806HMDB0006961;C05235HMDB0034122;C14567HMDB0035208;C16753HMDB0030475;C16754HMDB0014548;C06817HMDB0015004HMDB0012136;C05771HMDB0014328;C07514HMDB0014559;C06574HMDB0004350;C06180HMDB0036582;C08579HMDB0015503;C13244HMDB0030352;C10128HMDB0000052;C03406HMDB0041830;C06551HMDB0031310;C06556HMDB0014857;C07774HMDB0000944;C08281HMDB0015695;C02009HMDB0003119;C00556HMDB0029412;C08269HMDB0003422;C20144HMDB0015057;C08007HMDB0062659HMDB0006750HMDB0035710;C09066HMDB0125102;C01481HMDB0011634;C03375HMDB0002121;C09069HMDB0001564;C00570HMDB0015018;C07461HMDB0014500;C07931HMDB0005060HMDB0041857;C16765HMDB0015043;C01416HMDB0000015;C05488HMDB0002802;C00762HMDB0030180;C02633HMDB0030093;C10445HMDB0014578;C06935HMDB0000078;C01419HMDB0000124;C00085HMDB0000247;C00794HMDB0002835;C06938HMDB0011623;C12307HMDB0014942;C06951HMDB0094660;C14175HMDB0032562;C11016HMDB0014425;C06965HMDB0014960;C01692HMDB0000574;C00097HMDB0033923;C00407HMDB0062203;C16439HMDB0002005;C02989HMDB0000819;C05589HMDB0062263;C00065HMDB0000583HMDB0015259;C08069HMDB0015323;C09421HMDB0014610;C06979HMDB0029861HMDB0005056;C18166HMDB0015451;C01575HMDB0126018;C05631HMDB0030819;C09263HMDB0031791;C10988HMDB0040288HMDB0014747;C07665HMDB0060580;C14487HMDB0014731;C07505HMDB0001919HMDB0037270;C18787HMDB0005015;C07018HMDB0014812;C08526HMDB0030700;C10063HMDB0035830;C09780HMDB0002720HMDB0029455HMDB0028792HMDB0028829HMDB0015505;C07489HMDB0003584;C01959HMDB0000128;C00581HMDB0030310;C06536HMDB0000666;C17714HMDB0005782;C01709HMDB0061822HMDB0032323;C08306HMDB0014620;C06906HMDB0000870;C00388HMDB0003431;C00860HMDB0033433;C08283HMDB0000063;C00735HMDB0033701;C00353HMDB0060949;C14204HMDB0014917;C05079HMDB0037316;C08650HMDB0034972HMDB0031195;C14743HMDB0000684;C01718HMDB0062186;C00049HMDB0002706;C00308HMDB0000684;C00328HMDB0001645;C01933HMDB0000716;C00408HMDB0062698;C00449HMDB0032358HMDB0001190;C01591HMDB0014426;C07073HMDB0004385;C06314HMDB0034666;C00561HMDB0015069;C07107HMDB0035698;C10682HMDB0015177;C13736HMDB0001921;C07151HMDB0014901;C07190HMDB0014703;C01937HMDB0014693;C01864HMDB0036583;C11512HMDB0000745;C00884HMDB0001522;C02294HMDB0001932;C07202HMDB0015146;C07205HMDB0014523;C07220HMDB0014380;C07224HMDB0041938;C07451HMDB0030386;C10160HMDB0010699HMDB0000212;C01074HMDB0002284HMDB0060611HMDB0011758HMDB0094692;C02721HMDB0004370;C06213HMDB0031642;C19285HMDB0029586HMDB0015072;C06954HMDB0002670;C00509HMDB0001934;C16150HMDB0014545;C07699HMDB0014723;C07270HMDB0060657;C16576HMDB0036328;C20216HMDB0003011;C00979HMDB0032582;C02499HMDB0015215HMDB0015224;C01443HMDB0014980;C07359HMDB0014640;C08018HMDB0012273HMDB0013648HMDB0013654HMDB0014944;C07424HMDB0003647;C02576HMDB0000821;C05598HMDB0014337;C07438HMDB0012275/HMDB0060276;C05332HMDB0015217;C07474HMDB0015095;C07445HMDB0034301;C01746HMDB0000852;C07892HMDB0014645;C01814HMDB0000824HMDB0001849;C07407HMDB0002685;C06475HMDB0001381;C00427HMDB0014488;C07408HMDB0034580;C10865HMDB0130987;C10287HMDB0000239;C00314HMDB0033135;C11180HMDB0037113;C18487HMDB0003236;C06543HMDB0030321HMDB0029888HMDB0001257;C00315HMDB0013078HMDB0000848HMDB0036706;C20212HMDB0014347;C07546HMDB0014933;C07316HMDB0015619;C11169HMDB0015009;C07129HMDB0005814;C08157HMDB0015592;C11168HMDB0015175;C07910HMDB0001889;C07130HMDB0014868;C07131HMDB0034732HMDB0035030;C08325HMDB0014447;C12535HMDB0000930;C00423HMDB0000954;C01494HMDB0000601;C04722HMDB0015575;C09314HMDB0240288;C07182HMDB0029367;C00729HMDB0000295;C00015HMDB0000301/HMDB0034174;C00785HMDB0005016;C07187HMDB0000881;C02470HMDB0015640;C07913HMDB0015097;C07484HMDB0014460;C07218C06082C16165C10462C10664C15553C06473C15673C06670C22127C17335C05822C21168C13672C09313C06315C17495C00732C17590C02013C08476C00333C00476C06468C02522C02273C01125C01432C08942C16526C09732C08449C09929C08945C08866C09783C12888C10696C10067C16980C16883C02983C01114C16985C03212C12989C18128C08073C17148C09281C07393C18021C10720C08633C00639C08972C06415C17058C12081C05610C01341C13666C09743C10840C14751C02483C05366C03203C14091C05964C02357C01801C04284C16393C17385C06165C14130C16213C02496C07101C07098C10712C03349C00944C14418C02124C07088C18653C01017C02811C13668C18083C14633C06087C18528C20142C09320C11033C06831C20035C10645C18597C08291C14225C20219C06878C00652C06601C09842C11379C04666C01182C10036C09419C13154C11020C00975C18509C18671C14283C13732C10858C06231C18399C18462C18401C09265C11863C10794C10421C08415C19132C06537C16971C05010C18598C18864C18865C08648C18504C02045C01100C10366C10646C10805C21130C01727C10651C18525C20396C11011C01705C05353C12508C08244C09954C14695C13734C19494C08378C18481C17045C09171C18742C05954C13802C05956C18584C00623C08247C09240C09643C01096C10996C14179C16868C18526C11682C01619C08260C07545C01630C11700C01987C12628C06193C05500C11321C11620C03493C03742C06343C07555C08043C03592C04418C02571C19990C06091C19315C09024C17457C09767C16627C01397C16915C04931C09538C11045C17798C11900C18415C06523C15687C16923C18776C11022C18395C11309C07709C08585C02256C09775C12729C11308C16931C18818C18508C06545C08858C08431C08794C08797C06685C03032C10983C08859C19953C19954C09943C09662C14686C10935C14227C18953C00792C00303C18786C10299C09154C12154C09164C09167C20945C03514C18726C09076C08817C09668C18912C10062C11222C07602C22128C10881C15676C10324C11225C10057C08688C07608C17555C10465C19047C19063C10472C10339C14064C00977C13470C08694C06462C10156C01433C16990C10503C18476C02989C05371C11086C11786C19914C06080C09279C19191C08775C19987C09145C12552C20070C07575C10746C11079C10874C09712C12816C01748C09179C10991C10333C10288C06688C09716C08780C10555C17064C16951C06176C10396C18435C10808C10820C02079C19096C10173C18896C14607C09654C09561C18512C12012C10826C14439C09742C18562C20709C18541C10848C05794C12112C10829C06544C07201C15181C17090C13077C14156C07344C16908C14269C02560C16843C02457C19463C14671C14765C11261C11260C10901C08497C14334C20126C11118C14794C14215C10619C12110C03354C19260C16394C13638C11584C19479C19303C14680C19265C01386C13630C01092C02115C18507C00946C08264C18700C20214C16913C11281C03047C18350C18702C14317C10910C10847C08618C10915C08813C16922C08707C14323C18529C16925C01897C11080C10030C16932C09362C08432C08800C18573C10798C18456C03752C09259C14554C06947C18781C19220C18782C10660C07620C10448C11782C10987C11233C18722C14469C02057C06971C16659C18828C08759C09187C06996C10679C18463C21550C07715C18668C15109C11864C05042C07034C03139C08305C07814C02821C19142C09112C07052C17958C09484C05334C06812C18779C10773C09128C18626C11114C07194C14332C09227C18477C12159C21200C04580C21197C21199C14405C11188C10719C01077C01118C18752C03425C00727C01839C09280C09705C10830C19495C00773C06975C10610C05151C14310C09528C19147C19012C18510C08180C10390C14186C18885C18760C01610C18590C18613C18554C18614C18803C08301C02106C19106C11172C14457C05175C14387C18540C18755C18769C07635C10955C07166C18615C10733C19097C10197C09981C20262