MetaboLightsapplication/xmlftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/m_MTBLS15130_LC-MS_negative_reverse-phase_v2_maf.tsvftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/m_MTBLS15130_LC-MS_positive_reverse-phase_v2_maf.tsvftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/s_MTBLS15130.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/i_Investigation.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/a_MTBLS15130_LC-MS_negative_reverse-phase.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/a_MTBLS15130_LC-MS_positive_reverse-phase.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/SD_N2_N.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/SD_N1_N.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/SD_N3_N.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/LD_C3_P.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/LD_C2_P.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/LD_N3_P.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/LD_N2_P.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/LD_N1_P.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/SD_C2_P.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/SD_C1_P.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/LD_N3_N.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/LD_C1_P.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/LD_N2_N.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/LD_N1_N.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/SD_N1_P.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/SD_N2_P.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/SD_N3_P.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/SD_C3_P.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/LD_C1_N.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/LD_C2_N.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/SD_C3_N.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/SD_C1_N.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/SD_C2_N.mzMLftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130/FILES/RAW_FILES/LD_C3_N.mzMLprimaryOK200ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15130<p>Metabolite identification was performed based on the in-house Metware Database using MS/MS spectral information. During data processing, signals from isotopes, adduct ions including K, Na, and NH4, and fragment ions derived from larger precursor molecules were excluded to eliminate redundancy.</p><p><br></p><p>Metabolite quantification was achieved using multiple reaction monitoring mode on a triple quadrupole mass spectrometer. In this mode, the first quadrupole selects the precursor ion of the target compound, while the third quadrupole isolates a specific characteristic product ion following collision-induced dissociation. This process minimizes non-target interference, ensuring high quantitative precision and reproducibility.</p><p><br></p><p>Upon data acquisition, peak areas for all metabolites were integrated. Subsequently, peak integration correction was performed for the same metabolite across different samples (Fraga et al., 2010).</p>MetaboLightsPublicLiquid Chromatography MS - negative - reverse-phaseLiquid Chromatography MS - positive - reverse-phase<p>The sample extracts were analyzed using an UPLC-ESI-MS/MS system UPLC, ExionLC AD and Tandem mass spectrometry system. The analytical conditions were as follows, UPLC: column, Agilent SB-C18 1.8 µm, 2.1 mm x 100 mm; The mobile phase was consisted of solvent A, pure water with 0.1% formic acid, and solvent B, acetonitrile with 0.1% formic acid. Sample measurements were performed with a gradient program that employed the starting conditions of 95% A, 5% B. Within 9 min, a linear gradient to 5% A, 95% B was programmed, and a composition of 5% A, 95% B was kept for 1 min. Subsequently, a composition of 95% A, 5.0% B was adjusted within 1.1 min and kept for 2.9 min. The flow velocity was set as 0.35 mL per minute; The column oven was set to 40°C; The injection volume was 2 µL. The effluent was alternatively connected to an ESI-triple quadrupole-linear ion trap QTRAP-MS.</p>Photoperiod-mediated transcriptional and metabolic reprogramming confers salt stress tolerance via the ascorbate-glutathione cycle and phenylpropanoid pathway in Ginkgo biloba.Peking UniversityDuo Keaiseedingsmass spectrometry assay<p>Using vacuum freeze-drying technology, place the biological samples in a lyophilizer (Scientz-100F),</p><p><br></p><p>then grinding (30 Hz, 1.5 min) the samples to powder form by using a grinder (MM 400, Retsch). Next, weigh</p><p><br></p><p>30 mg of sample powder using an electronic balance (MS105DΜ) and add 1500 μL of -20 °C pre-cooled 70%</p><p><br></p><p>methanolic aqueous internal standard extract (less than 30 mg added at the rate of 1500 μL extractant per 30</p><p><br></p><p>mg sample). Vortex once every 30 min for 30 sec, for a total of 6 times. After centrifugation (rotation</p><p><br></p><p>47speed 12000 rpm, 3 min), the supernatant was aspirated, and the sample was filtered through a microporous</p><p><br></p><p>membrane (0.22 μm pore size) and stored in the injection vial for UPLC-MS/MS analysis.</p>Ginkgo bilobahttps://www.ebi.ac.uk/metabolights/MTBLS15130yadi Chen. Yangzhou University. yadichen@yzu.edu.cn.weixing Li. Yangzhou University. liwx@yzu.edu.cn.<p>Raw mass spectrometry data were processed using Analyst 1.6.3 software (AB Sciex). The peak areas of the metabolites were extracted based on the retention time and specific MRM transitions defined in the method.</p>Groupkeaiduoduo998@126.com<p>One-month-old Ginkgo biloba seedlings grown in a greenhouse at Yangzhou University were transferred to hydroponic boxes containing either distilled water or 200 mM NaCl solution. The seedlings were then cultivated under two photoperiod regimes: 16 h light/8 h dark (long-day) and 8 h light/16 h dark (short-day). After one week of treatment, samples were collected, immediately frozen in liquid nitrogen, and stored at -80 °C until further use.</p>MetabolomicsGinkgo bilobaMetabolomicsSCIEX ExionLC ADtargeted analysisphenylpropanoid biosynthesissalt stressseedingsascorbate-glutathione cycleAB SCIEX QTRAP 6500photoperiodleafGinkgo bilobaMetabolomicsSCIEX ExionLC ADtargeted analysisphenylpropanoid biosynthesissalt stressseedingsascorbate-glutathione cycleAB SCIEX QTRAP 6500photoperiodleaf<p>The ESI source operation parameters were as follows: source temperature 500°C; ion spray voltage IS 5500 V positive ion mode and -4500 V negative ion mode; ion source gas I GSI, gas II GSII, curtain gas CUR were set at 50, 60, and 25 psi, respectively; the collision-activated dissociation CAD was high. QQQ scans were acquired as MRM experiments with collision gas nitrogen set to medium. DP declustering potential and CE collision energy for individual MRM transitions was done with further DP and CE optimization. A specific set of MRM transitions were monitored for each period according to the metabolites eluted within this period.</p>3-(10)-10-Pentadecenyl-1,2-benzenediolSchaftoside2-Decanol2-(2,3-dihydroxypropoxy)-3-(((2-(dimethylamino)ethoxy)(hydroxy)phosphoryl)oxy)propyl (11Z,14Z)-octadeca-11,14-dienoateAstraflavonoid CPratensein 7-O-glucopyranoside*PiceatannolGinkgoic acid1-Hexanol arabinosylglucosideIsohemiphloin2,5-dihydroxy-1,3-dimethoxy-6-methylanthracene-9,10-dioneDihydrokaempferolAdipate*D-GlycerateQuercetin 3-sulfate1-O-Feruloyl-beta-D-glucoseOctyl 6-O-Alpha-L-Arabinopyranosyl-Beta-D-Glucopyranoside6''-Carboxyraffinose3-O-Methylellagic acid 4-sulfate*5-O-(3'-O-Glucosylcaffeoyl)Quinic AcidGinnalin C (2-O-Galloyl-1,5-Anhydro-D-Glucitol)2,3-Dihydroamentoflavone 4'-methyl Ether*Buddlenol E1-O-p-Coumaroylquinic acid*Vitrofolal ATerephthalate2-Hydroxyhexadecanoic acid*Hesperetin-5-O-glucoside3,4-Methylenedioxyellagic AcidFerulic acid-4-O-glucoside3-Methoxybenzoic acid4-HydroxybenzaldehydeGnetifolin B*7''-O-MethylamentoflavoneIroneAlpha-Methyl-DL-PhenylalanineFormylanthranilateTamarixetin-3-O-rutinoside7-O-Methylamentoflavone*3,7-Dimethyl-8-Hydroxy-2,6-Octadienyl Beta-D-Glucopyranoside1-Hydroxypinoresinol-4'-O-Glucoside(1s,2e,6e,10z,14s)-14-hydroxy-3-isopropyl-6,14-dimethyl-15-oxabicyclo[8.4.2]hexadeca-2,6,10-trien-16-one3',5'-Cyclic GMP4-Hydroxycinnamyl aldehyde(R,R)-Tartaric acid3-(8,10,12-Heptadecatrienyl)-1,2-benzenediolVicenin-3Glutathione12,13-DHOMEKaempferol-7-O-glucoside*Mussaenosidic acidSyringetin-7-O-glucoside*1-O-Salicyloyl-¦Â-D-glucoseN-carboxy-N-(2-oxo-2-phenylethyl)-L-alanineLimocitrin-3-O-glucoside*Cagayanone APiperonylic acid4,5,8-Trihydroxy-¦Á-tetralone-5-O-glucosideMearnsetin-3-O-glucoside*Kaempferol-7-O-rhamnoside(S)-2-Aceto-2-hydroxybutanoateN-(malonyl)tryptophanDehydroxy-Dihydroabscisic Acid 4'-O-glucoside3-Hydroxyoctanedioicacid(+/-)-6-Hydroxy-3-oxo-alpha-ionol5,7-Dihydroxy-2'-methoxy-3',4'-methyleneoxydihydroisoflavone*N-(1-Deoxy-1-fructosyl)LeucineHydroxyAloe-emodin-8-O-glucosidedGDP*2-hydroxynaringenin*Isocoreopsin*Gallic Acid 4-O-Glucoside4,6-Dihydroxy-2-[(4-Hydroxy-3,5-Dimethoxyphenyl)Methylidene]-1-Benzofuran-3-OneGlucosyl 2,3-Dihydroxy-2-Methylbutanoic AcidVanillate5S,8R-DiHODE1-Caffeoylquinic acidGlyceraldehydeMaesopsin*Tichocarpol A*4-Coumaryl alcoholErucic acidFarrerol-5,7-di-O-glucoside12(S)-HETERobininRoseoside8-Methoxykaempferol-7-O-rhamnoside2,3-Dihydroxybenzoate*3-Galloylshikimic acid7,2',4'-Trihydroxy-8,3'-dimethoxyisoflavanglucoside5,7,8-trihydroxy-6-methoxy-2-(4-methoxyphenyl)chromen-4-one(E)-caffeyl alcohol 4-O-¦Â-D-glucopyranoside1-Octanol RhamnosylglucosideRutinoseQuercimeritrin*HarpagideCoumaroyl Quinic Acid1-O-Galloyl-2-O-p-Coumaroyl-¦Â-D-glucose7R,8S-erythro-3',4,9,9'-tetrahydroxy-3-methoxy-8-O-4'-neolignan-7-O-glucopyr-anoside,Manglieside DEugeniinDihydrophaseic acidDL-3-Phenyllactic acid*4-(3,4-dihydroxyphenyl)-7-hydroxy-5-[(3,4,5-trihydroxy-6-{[(3,4,5-trihydroxyoxan-2-yl)oxy]methyl}oxan-2-yl)oxy]-2H-chromen-2-oneEucommin A*2-¦Â-D-Glucopyranosyloxy-4-methoxy-cis-cinnamic acidIsobiflorinTricin-4'-O-(guaiacylglycerol)ether*DemethylsyringinTheasinensin CChrysoeriol 5-O-beta-D-glucopyranosyl-(1¡ú2)-O-[alpha-L-rhamnopyranosyl-(1¡ú6)]-beta-D-glucopyranoside3,3'-Dihydroxy-5-methoxybibenzylAdenosineIsoginkgetin*Myricetin-3-O-neohesperidoside3-O-(3,5-Dimethoxy-4-hydroxybenzoyl)-4-O-caffeoylquinic acidD-Glucose*Andropanoside3-DehydroshikimatePhloretin-4'-O-glucoside (Trilobatin)*Tracheloside*3,4-Dimethoxyphenyl acetic acidResveratroloside*(S)-2-AcetolactateD-Erythrose 4-phosphate(9S)-Hydroxyoctadecadienoic acid1,5-Anhydro-D-glucitol7''-O-Glucosyl-ginkgetin*Quercetin-3,7-Di-O-glucoside9,12,13-Trihydroxy-10,15-octadecadienoic acidJusticiresinol xyloside2-hydroxy-6-(tridec-6-en-1-yl)benzoic acid1'-(3-isobutyl)-3-hexanoyl-3'-octanoyl-sucroseEriodictyol-7-O-rutinoside-4'-O-Sophoroside6-O-Caffeoyl-D-glucose*AfzelinBenzyl-(2''-O-xylosyl)glucosideNepetin-7-O-glucoside(Nepitrin)4-Hydroxy-2-quinolinecarboxylic acidPhloretin-2'-O-(6''-O-glucoside)glucosideDL-O-tyrosine20-Carboxyarachidonic Acid(2Z)-2-[(3,4-dimethoxyphenyl)methylidene]-5,6-dimethoxy-3H-inden-1-oneSecoisolariciresinol diglucosideTricetin 7-O-glucuronide*3-O-p-Coumaroylquinic acid-O-glucoside4-acetoxy-2-geranyl-5-hydroxy-3-n-pentylphenol3-O-Feruloylquinic acid-O-glucoside1-(¦Â-D-Glucopyranosyl)-3-ethyl-4-methyl-1H-pyrrole-2,5-dioneDimethylglyceric Acid Glucoside7S,8R-threo-3',9,9'-trihydroxy-3-methoxy-4',7-epoxy-neolignan-4-O-rhamnosideOctanoyl arabinosylglucoside9,12,13-TriHOME4',4''',5,5'',7,7''-Hexahydroxy-3',6''-biflavanone1-(4-Hydroxy-3-methoxyphenyl)-2-[4-(1,2,3-trihydroxypropyl)-2-methoxyphenoxy]-1,3-propanediolisatioxyneolignoside EEriodictoyl-7-O-sophorosideStrictinin*isatioxyneolignoside A5,7-Dihydroxy-4-oxo-2-(3,4,5-trihydroxyphenyl)-4H-chromen-3-yl-allosideEpigallocatechin gallate*2-Palmitoyl-Sn-Glycerol 3-O-DiglucosideNorartocarpetin*Corilagin*Mucic acid-1,4-lactone-3,5-di-O-gallatetetrahydrodehydrodiconiferyl alcohol glucosideFeruloyloctose*Erythro-Guaiacylglycerol-¦Â-O-4'-dehydrodisinapyl EtherTheaflavate B;3'-O-(3,4,5-Trihydroxybenzoyl)gamma-L-Glutamyl-L-cysteinePinocembrin chalcone1-O-Vanilloyl-beta-D-glucose1,6-dihydroxy-3,7-dimethoxy-8-(3-methoxy-3-methylbutyl)-2-(3-methylbut-2-en-1-yl)xanthen-9-oneLysoPG 16:04-Hydroxyphenylacetate7-(6-hydroxy-4-pentylcyclohex-2-en-1-yl)heptanoic acidTortoside A*Nepetariaside7-ethenyl-10a-hydroxy-1,4b,7-trimethyl-decahydrophenanthrene-1-carboxylic acidCimidahurinine5-hydroxy-3,4-dimethyl-5-pentylfuran-2(5H)-one*DGMG 18:2DGMG 18:3DGMG 18:1Malic acid-1-O-glucopyranosideXanthosinedGMPPhthalic acid,6-ethyl-3-octylbutyl esterDihydromyricetin-3-O-glucosideDihydrocoumaroyl Hexoside*Datiscetin3-O-Feruloylquinic acidMonomethyl succinate*Acetyl 4-Aminophenyllactic[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl](2E,4E)-5-[(1R,3S,5S,8S)-3,8-dihydroxy-1,5-dimethyl-6-oxabicyclo[3.2.1]octan-8-yl]-3-methylpenta-2,4-dienoate9,12,13-Trihydroxy-10-octadecenoic acidPatuletin-7-O-Galactoside*Epipinoresinol*Chrysoeriol-8-C-glucoside (Scoparin)(6Z)-2-Methoxy-6-pentadecenoic acidGlutathione disulfideAgrimonolide5'-methoxybilobetiniristectorigenin B-7-O-¦Â-glucosyl(1¡ú6)glucoside2-OxoglutarateDihydrophelloside3-Oleoyl sucrose2-(2,3-dihydroxypropoxy)-3-(((2-(dimethylamino)ethoxy)(hydroxy)phosphoryl)oxy)propan-2-yl (Z)-14-Octadecenoic Acid3-O-(3-Methoxy-4-hydroxybenzoyl)-4-O-caffeoylquinic acid2-((6-hydroxy-4-(hydroxy(methoxy)methyl)-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-1-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triolL-Aspartate*Syringetin-3-O-rutinosideNeochlorogenic acid*Myricetin-3-O-xyloside*3-[4-(Beta-D-Glucopyranosyloxy)Phenyl]Propionic Acid*Glutarate*1,2,4-Trihydroxynaphthalene-1,4-di-glucoside (Lawsoniaside)Salicin 6'-AcetateArtocarpanoneGlucosyl 6-methylhept-6-ene-1,2,3,4,5-pentaolNaringenin-5-methyl etherDrimiopsin C*PoncirinIsosakuranetin 7-Alpha-L-Arabinofuranosyl-(1¡ú6)-Glucoside(2R,3R)-3,5,7,3',5'-PentahydroxyflavanD-Arabinose*DGMG 18:1(2n isomer)SalirepinSalviaflaside3'-p-Coumaroyl-sucroseHellicoside1-Methoxybenzoyl-6-O-Galloyl-D-GlucoseEucommiosideMonobutyl phthalateCarthamidin4-O-galactopyranosylxyloseMangiferinAminomalonategnetifolin EIsorhamnetin-3-O-glucoside-7-O-rhamnosideSibiricose A6UDP-D-galactose3-O-Methylellagic acid 4'-rhamnoside2-Hydroxy-7-carboxy-1-methyl-5-ethenyl-9,10-dihydrophenanthrene*Bilobetin-7-O-glucoside1-O-Caffeoyl-(6-O-glucosyl)-¦Â-D-glucose3-oxo-2-[(2,4,5-trimethoxyphenyl)methylidene]-1-benzofuran-6-yl 4-tert-butylbenzoate1-O-(3,4,5-Trimethoxybenzoyl)-B-D-Glucopyranoside2-OxoadipateRobustaflavone*Pinobanksin*4-Hydroxyhex-2-enoic acid*4-O-Feruloylquinic acid4-(3-Hydroxyphenyl)-4-(beta-D-glucopyranosyloxy)butyric acidIsocitric acid-1-O-diglucoside1-O-Feruloyl 9,10,12,13-tetrahydroxynonadecanoic acid(2S,3R)-2,3-dihydroxy-5-oxohexanedioic acidPrunetin (5,4'-Dihydroxy-7-methoxyisoflavone)6-Geranylnaringenin; Mimulone; Bonannione AGlycerone phosphatekaempferol-3-methoxycaffeoyldiglucosideD-Ribose5,7,2'-Trihydroxy-8-methoxyflavone*BilobolN-Alpha-Acetyl-L-AsparagineDihydromareinSoraphen ODemethylgeranyl 6-O-xylopyranosyl-glucopyranoside1-(2,3-dihydroxypropoxy)-3-(((2-(dimethylamino)ethoxy)(hydroxy)phosphoryl)oxy)propan-2-yl (Z)-14-Octadecenoic AcidNyasolProtocatechuic Acid Methyl EsterClemastanin AXanthurenic Acid 8-O-GlucosideDihydroxyoctanoic acid glucosideIsolariciresinol2'',3''-Dihydrorobustaflavone 7,4'-dimethyl etherGastrodinTetrahydro-2-(4-Hydroxy-3-Methoxyphenyl)-6-(Alpha,4-Dihydroxyphenethyl)-4H-Pyran-4-OlD-GalactarateTridecanedioic acid2-trans-abscisic acid D-glucosyl esterArecatannin B1NodakeninTribulosideKaempferol-3,7-O-diglucosideIsorhamnetin-3-O-arabinoside-7-O-rhamnoside1-Hydroxypinoresinol-1-O-Glucoside*3-[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybenzoic acidCatecholN-Acetyl-L-threonineTrifolirhizin2¦Á,3¦Á-Epoxy-5,7,3',4'-tetrahydroxyflavan-(4¦Â¡ú8)-catechin11-Hydroxyazadirachtin BSyringaldehyde; 4-Hydroxy-3,5-Dimethoxybenzaldehyde2'3'4'-Trimethylcalythropsin 2-O-glucosideNortrachelogenin-4-O-glucosideKoaburaside2-Benzylsuccinic AcidSalicin9-Hydroxy-12-oxo-15(Z)-octadecenoic acid*2,6-Di-(4-hydroxycinnamoyl)glucoside3,4-Dihydroxyallylbenzene-4-O-xylosyl(1¡ú6)glucoside2-hydroxy-2-isobutylsuccinic acidProtocatechuic acid 1-O-(Glucosylvanilloyl)N-succinyl-proline1-O-Sinapoyl-beta-D-glucose1-O-Acetyl-Glucopyranose 6-DecanoateUDP-D-xylose1-O-Gentisoyl-¦Â-D-glucosideNeosakuranin2-(3,5-Dihydroxy-4-Methoxyphenyl)-5,7-Dihydroxy-4H-1-Benzopyran-4-OnePhenylacetylaspartic acid6-Hydroxykaempferol-7-O-glucosideGlucosyringic acid2',8''-Biapigenin*4-[(1E,4E)-5-(3-hydroxyphenyl)penta-1,4-dien-1-yl]phenolEpigallocatechin-(4¦Â¡ú8)-catechin2,6-Dihydroxy-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybenzoic acidD-Fructose*2,6-Dimethyl-7-octene-2,3,6-triolsec-o-GlucosylhamaudolPodocarpusflavone B*D-ThreonateSuspensoside AMethylmalonate*Epicatechin-4'-O-¦Â-D-glucopyranoside*dCMP10-Hydroxydecanoic acid glucoside1-(3-Methoxy-4-Hydroxyphenyl)-2-[2-Methoxy-4-[(E)-3-Hydroxy-1-Propenyl]Phenoxy]-3-Hydroxypropyl Beta-D-GlucopyranosideIlicifolinoside BMethyl cumalateSoyasapogenol BTricin-7-O-(6''-O-acetyl)glucoside3-[(2S,3S)-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-3-methyl-2,3-dihydro-1-benzofuran-5-yl]prop-2-enal1-Octen-3-Yl Primeveroside2(3H)-BenzothiazoloneQuercetin-5-O-glucuronide*Uracil5-O-p-Coumaroylshikimic acid O-glucosideLaricitrin-3-O-(6''-acetyl)glucosideOlivilN-(E-4-coumaroyl)-aspartateRheinIsoetin*Mandelic acid-¦Â-glucoside2-Hydroxy-4-methylpentanoic acid2,6-Di-tert-butyl-4-hydroxymethylphenolMalonateAICAR phosphate (Acadesine phosphate)Luteolin-7-O-neohesperidoside (Lonicerin)*Polygonimitin B2-(2,3-dihydroxypropoxy)-3-(((2-(dimethylamino)ethoxy)(hydroxy)phosphoryl)oxy)propyl palmitate*1-Naphthol*CannabiscitrinIminodiacetate*alpha-IsopropylmalateEriodictyol-7-O-glucuronide(+)-Pinoresinol*Machilusolide D2-hydroxy-6-[(Z)-undec-6-enyl]benzoic acidDehydroascorbate(2R,3R,4S,5S,6R)-2-[3-(2,4-dihydroxyphenyl)propoxy]-6-(hydroxymethyl)oxane-3,4,5-triol1,8-dihydroxy-4,5-dimethoxy-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}xanthen-9-oneQuercetin-3-O-robinobioside3'-O-Beta-D-Glucopyranosyl plumbagic acidampelopsin C3,7-Dimethylocta-2,6-Diene-1,4-Diol 1-O-Beta-D-Glucopyranoside2-Hydroxy-2,3-dihydrogenistein*Pantetheine 4'-phosphate2,4-Dihydroxy-6-(8Z)-8-pentadecen-1-ylbenzoic acid6-Methylaloe emodin3,5-dihydroxy-2-tridecylbenzoic acid5,15-O-Dimethyl morindolMalateampelopsin EAracarpene 2*MareinSciadopitysin-5-O-glucoside¦Â-HydroxyacteosideD-erythro-3-Methylmalate*3-Hydroxypropanoate7-O-GalloyltricetiflavanTheaflavic acid3-methyl-4-(15-oxohexadecyl)furan-2,5-dioneOlivil-4'-O-glucoside1,4-O-dicaffeoyl-3-O-succinoyl-quinic acidsorbose*2-[3,5-dihydroxy-2-[4-[4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-(hydroxymethyl)oxolan-2-yl]-2-methoxyphenoxy]-6-(hydroxymethyl)oxan-4-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol*1,7-dihydroxy-2-(hydroxymethyl)anthracene-9,10-dioneUrolignoside*Rumexobtusifoliusp-Hydroxypheny-¦Â-D-allopyranoside3-Hydroxyoctadecanoic Acid4'-O-beta-D-Glucosyl-cis-p-coumarate(-)-EpicatechinTetrahydroxyflavan-(4¦Á-8-epicatechin)Theogallin3,7-Di-O-methylquercetinHydroxypentadecenoic acid glucosideNADP+Beta-Hydroxypalmitic Acid*(X)-1,2-Propanediol 1-O-B-D-GlucopyranosideCatalpolTricin-5,7-O-diglucoside*2,3,23-Trihydroxyolean-12-ene-28,29-dioic acid 29-methyl ester (Phytolaccagenin)17-(4-methyl-2,5-dioxo-2,5-dihydrofuran-3-yl)heptadecyl acetate2,5-dihydroxy-1-methoxy-anthraquinone2-Feruloyl-6-(4-hydroxycinnamoyl)glucosideBrevifolin carboxylic acid3,4-bis(2-ethylhexyl)benzene-1,2-dicarboxylic acidMorin*2-Propylmalate*3-Hydroxyglutaric acidProcyanidin B11,5-O-dicaffeoyl-3-O-succinoyl-quinic acid3-O-(4'-O-caffeoylglucosyl)quinic acidIsoascorbic acid 2-O-glucoside2,5-dihydroxy-1,6-dimethoxy-8-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}xanthen-9-oneRobustaflavone-7''-methyl etherGeranyl 3-O-xylopyranosyl-glucopyranosideDGMG 18:3(2n isomer)D-ErythronolactoneLaminarinQuercetin-3-O-(6''-O-acetyl)galactoside2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone2',3',4',5,7-pentahydroxyflavone*12-Hydroxydodecanoic acidProcyanidin C25,8¦Á-dioxy-3¦Â,16¦Á-dihydroxyl-lanost-7(11),24-dien-21-oic acidProcyanidin B44'-MethoxyresveratrolTricin-4'-O-glucoside-7-O-glucoside*Procyanidin B2Procyanidin B3Naringenin (5,7,4'-Trihydroxyflavanone)*13(S)-HOTE,E,Z-1,3,12-Nonadecatriene-5,14-diol1-(4-Hydroxy-3,5-dimethoxyphenyl)propane-1,2,3-triol-glucoside4-O-Glucosyl-3,4-dihydroxybenzyl alcoholmyo-Inositol 4-phosphatepentylO-beta-(2'-O-beta-D-glucopyranosyl)-D-glucopyranosideEthanolamine phosphate5-Glucosyloxy-2-Hydroxybenzoic acid methyl esterAmentoflavanoneOxalateGlucosyl 2-Hydroxy-4-Methylpentanoic Acid5-methoxycarbonylpentyl alpha-D-mannopyranoside3'-O-Methylellagic acid-4-O-glucuronide10,16-Dihydroxyhexadecanoic acidIsorhamnetin 3,4'-DiglucosideHypolaetin*Feruloyl Lactate1-(2,3-dihydroxypropoxy)-3-(((2-(dimethylamino)ethoxy)(hydroxy)phosphoryl)oxy)propan-2-yl (11Z,14Z)-octadeca-11,14-dienoate2-hydroxy-4-pentadecylbenzoic acidQuercetin-3-O-(2''-O-rhamnosyl)galactosideDihydrocharcone-4'-O-glucoside*L-Glutamyl-L-Cysteinyl-Glycine3-O-p-Coumaroyl 2,3-dihydroxypropyl-3-Hydroxytetradecanoate2-Methylguanosine9-hydroxy-8-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1H,3H-naphtho[2,3-c]furan-1-oneKaempferol-3-O-(6''-O-acetyl)glucoside2-Deoxy-D-ribose 1-phosphate*Tryptophan(3S,4S,5R)-2-(((2R,3S,4S,5R,6R)-6-(((2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methoxy)-3,4,5-trihydroxycyclohexane-1-carboxylic acid2¦Á,3¦Á-Epoxy-5,7,3',4'-tetrahydroxyflavan-(4¦Â¡ú8)-epicatechin4'-HydroxyacetophenoneXanthine4-O-(4'-O-alpha-D-Glucopyranosyl)caffeoylquinic acidLuteolin 7-O-beta-D-glucoside*5,7-dihydroxy-6,8-dimethoxy-3-(4-methoxyphenyl)chromen-4-oneTricetinHedyotol Cindigoticoside A*Apigenin-5-O-glucosideGlucosyl 6,9-dihydroxydec-4-enoic acid4'-O-methyl robustaflavone*Kaempferol-3-O-(4''-(E)-p-coumarylrobinobioside)1,3,6,8-tetrahydroxy-2,5-dimethoxyxanthen-9-one(2S,3R,4S,6S)-2-[4-[(1R,2R)-1,3-Dihydroxy-2-[4-[(E)-3-hydroxyprop-1-enyl]-2,6-dimethoxyphenoxy]propyl]-2,6-dimethoxyphenoxy]-6-(hydroxymethyl)oxane-3,4-diol13-Amino-13-oxotridecanoic acid7,8-Dihydro-Buddlenol BD-Glucuronate*MajorosideEriodictyol chalcone3,7-Dihydroxy-2-(4-Hydroxy-3,5-Dimethoxyphenyl)-4H-1-Benzopyran-4-OneUndecanedioic acid4-hydroxy-2-(14-hydroxypentadecyl)-6-methoxybenzoic acidWedelolactoneDiosmetin*trans-CinnamateQuercetin3-O-|A-D-(6''-p-coumaroyl)glucopyranosyl(1-2)-|A-L-rhamnopyranoside5,7-dihydroxy-6,8-dimethoxy-2-(3-methoxyphenyl)-4H-chromen-4-oneChrysoeriol-6-C-glucoside-4'-O-glucosideCaffeoyl-p-coumaroyltartaric acid2,6-dimethoxybenzene-1,4-diol 1-O-¦Â-D-glucopyranoside8-[2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2h-1-benzopyran-4-yl]-2-(4-hydroxyphenyl)-3,4-dihydro-2h-1-benzopyran-3,5,7-triolLaricitrin-3-O-xyloside7-DeoxyloganateCantleyineD-Galacturonate*(2R,3R,4S)-2,4-Dimethyl-5-Oxotetrahydrofuran-3-Carboxylic AcidGardoside3',5'-Cyclic AMPGallocatechin 3-O-gallate*(10E,12Z,15Z)-9-oxooctadeca-10,12,15-trienoic acidSalicylic acid-2-O-glucosideUrocanate6-Hydroxyluteolin 5-glucoside*Resveratrol-4'-O-¦Â-D-(6''-O-galloyl)-glucopyranosideEthylmalonic acid*Kaempferol-3-O-(6'''-Caffeoyl)glucosyl-(1¡ú2)-GalactosideKaempferide*N-Acetyl-L-glutamate3,5,3',4',5'-penta-hydroxyflavan-7-gallate*(Indol-3-yl)acetyl-L-aspartateN1-(5-Phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazoleD-Fructose 6-phosphate*3,4-dihydroxy-allylbenzene-3-O-¦Â-D-glucopyranosideSedoheptulose 7-phosphate(1S,4aS,7aR)-7-(3-hydroxybutyl)-4-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-1-yl acetateLuzonoside C2¦Á,3¦Á-Dihydroxyolean-12-en-28-oic acid5-Hydroxyferuloylquinic acidkaempferol-3-caffeoyldiglucoside8-Hydroxypinoresinol 4-Glucoside*Chrysoeriol-7-O-glucoside*Myricetin-3-O-rutinosideDihydrogenistin*(2s,3r,4s,5s,6r)-2-{[(2r,3r,4s,5s,6r)-2-(hexyloxy)-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triolArecatannin C1Sorbitol 6-phosphateGinkgoside ATricin-5-O-guaiacylglycerol*3-Crotonyl-3'-(3-methylbutanoyl)sucrose3-O-Methylgallate(+)-PiperitolCinnamtannin A1N-Acetyl-L-aspartateEchinacoside2,5-dihydroxy-6-methoxy-9-phenylphenalen-1-oneConiferyl alcoholVelutin (5,4'-dihydroxy-7,3'-dimethoxyflavone)*(2R,3S,4R,5R,6S)-3,4,5,6,7-pentahydroxy-2-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}heptanal*Loureirin Calpha,alpha'-Trehalose 6-phosphate5'-Glucosyloxyjasmonic acidCryptochlorogenic acid (4-O-Caffeoylquinic acid)*Dehydroabietic acidKaempferol-3-O-sophoroside-7-O-rhamnoside6-Hydroxyhexanoic acidQuercetin-3-O-arabinosideDihydromyricetin2,4-Dihydroxy-3,5-bis(3-methylbut-2-enyl)-6-pentylbenzoic acid3-Oxopentanedioic acidIsoferulic Acid*Aromadendrin-3-O-rhamnoside; Engeletin3-(4-Hydroxyphenyl)lactate*Epicatechin 3-glucosidePropyl 4-hydroxybenzoate3-Hydroxy-3-methylglutarateCitric acid glucoside4-Hydroxy-3-methoxy-benzaldehydeL-FucitolAbyssinone II(S)-3-Methyl-2-oxopentanoic acid*5-O-p-Coumaroylquinic acid O-glucosidePorrigenic acidAucubinGingerglycolipid BHerbacetin-3,8-Di-O-glucoside(9Z,12Z,15Z)-Octadecatrienoic acid*Gingerglycolipid C5-AcetamidopentanoateGingerglycolipid ADihydrokaempferol-7-O-glucosideD-Arabinono-1,4-lactoneBridelionoside B3-O-p-Coumaroylshikimic acid-O-glucoside2-(2,3-dihydroxypropoxy)-3-(((2-(dimethylamino)ethoxy)(hydroxy)phosphoryl)oxy)propyl (8E,11Z,14Z)-octadeca-8,11,14-trienoate8-O-Acetylmussaenoside2-Hydroxy-8-carboxy-1-methyl-5-ethenyl-9,10-dihydrophenanthrene*Epicatechin-3'-O-¦Â-D-glucopyranoside*9,10,13-TriHOME(2R,3R,4S,5R,6R)-6-[(2R,3R,4R,5R,6S)-4,5-dihydroxy-2-(hydroxymethyl)-6-(4-methoxyphenoxy)oxan-3-yl]oxy-2-(hydroxymethyl)-5-(methoxymethoxy)oxane-3,4-diolMakomotine CErigeside B4,5,8-Trihydroxy-¦Á-tetralone-5-O-[6'-O-(4''-acetoxylbenzoyl)]glucoside2,3-Dihydroamentoflavone 7'''-methyl Ether*D-Galactose*Frehmaglutoside GCitric acid-1-O-diglucoside2-crotonylsucroseAstilbin2,3-Dihydroamentoflavone6-Hydroxykaempferol-3,6,7-O-triglucosideAloe emodin anthroneHamiltone AGinkgolide B3,4-Dimethylellagic acid 4'-sulfateFisetinidol-(4¦Á,6)-gallocatechinPodocarpusflavone AImperanene glucosideAromadendrin-7-O-glucoside*8''-O-Glucosyl-isoginkgetin*Grevilloside F3-Hydroxyisovalerate2,3,19,23-Tetrahydroxyurs-12-en-28-oic acidDihydrodehydrodiconiferyl alcoholCitrateSequoiaflavone-5-O-glucoside*Ascorbatesyringaresinol-4-O-glucoside*Glyceraldehyde 3-phosphate1-(4-Hydroxybenzoyl)Glucose; 25545-07-7Homomevalonic Acid GlucosideMethyl 2,4-dihydroxyphenylacetate*3-Methyl-4,8-dihydroxy-3,4-dihydroisocoumarinPiceid*Benzyl gentiobioside*Phenyllactate1-O-rhamnose-3-O-Caffeoyl Quinic AcidRumphioside BMethyl gallate*Podocarpusflavone A glucoside*Methyl 3-O-Beta-Glucopyranosyl-Gallate2,3-Dihydrosciadopitysin2-O-Caffeoylglucarate1-(2,3-dihydroxypropoxy)-3-(((2-(dimethylamino)ethoxy)(hydroxy)phosphoryl)oxy)propan-2-yl palmitate*FerreirinChicoric acidcis-Aconitate3,3'-O-Dimethylellagic AcidUridineKaempferol-4'-O-glucosideD-Gluconic acidL-threo-3-MethylaspartateVicianose¦Â-Hydroxy-(3,4-dihydroxyphenylethanolyl)-glucoside(6Z,9Z,12Z)-Octadecatrienoic acid*Bilobetin*Quercetin*Salvadorasidedihydrodehydrodiconiferyl alcohol-9-O-¦Â-D-glucopyranoside4-(Beta-D-Glucopyranosyloxy)-2,4',6-TrihydroxybenzophenoneDehydrodiconiferyl alcohol9,16-Dihydroxypalmitic acidTricetin 5-(4''-galloylrhamnoside)Demethyl coniferinD-¦Á-D-Hep-(1¡ú6)-¦Â-D-Glc*Rubusin BMorin-3-O-arabinoside*3'-linoleoyl sucrosebutyl 3-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}butanoateS-Ribosyl-L-homocysteine1,6-anhydro-¦Â-D-glucose5,7-Dihydroxy-2-(2-Hydroxyphenyl)-6,8-Dimethoxy-4H-1-Benzopyran-4-One*coleoside-BLuteolin-4'-O-glucoside*5-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]pentanoic acidGambiriin A1ArachidonateN-Acetyl-D-glucosamine 1-phosphateSakuranin5,3'-Dihydroxy-7,4'-Dimethoxyflavonelaricitrin-7-O-rhamnosideGlucaric acid-1-PhosphateMyricetin-3-O-arabinoside*3,5-Dinitrosalicylic acidMelilotoside4-O-(6'-O-Glucosylcaffeoylglucosyl)-4-hydroxybenzyl alcoholD-Ribulose 5-phosphate10-O-Caffeoyl-geniposidic acidHomoeriodictyol p-Coumaroyl apiosyl glucoside3,4-Dihydroxyphenylacetate*Hexadecanalent-3¦Á,16¦Â,17,19-Tetrahydroxykauran-19-ylacetate-17-O-¦Â-D-glucopyranoside2(R)-HOT6-O-DihydrocaffeoylglucoseChlorogenic acid methyl esterPhloretinmethyl 2-[(2E)-3-ethyl-5-[(3E)-2-ethylhept-3-en-1-yl]-2,5-dihydrofuran-2-ylidene]acetateHomovanillic acid sulfate*Hydroperoxylinoleic acid*sn-1-O-(cis-12-oxophytodienoyl)-sn-3-O-(beta-D-galactopyranosyl)glyceride3'-Norspongiolactone5'-Methoxymatairesinoside*Mansorin IIItrans-2-Hydroxycinnamate*3-Dehydro-L-gulonate 6-phosphate6-Hydroxyluteolin 7-rutinosidep-Menth-4(5)-ene-1,2-diol-1-O-¦Â-D-(2-O-acetyl)-glucoside5,7-DihydroxycoumarinADP*3,4-dimethoxy-2-[(3,4,5-trihydroxy-6-{[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy]methyl}oxan-2-yl)oxy]xanthen-9-oneLariciresinol 4-O-glucosideMethyl 4-hydroxybenzoateSenkyunolide I2-Phenylethyl beta-primeveroside5-O-Galloyl-D-hamamelose*Tricin-5-O-GlucosideIsolariciresinol-9'-O-glucoside*Kaempferol-3-O-Gentiobioside-7-O-Rhamnoside*AmentoflavoneTetrahydroswertianolinBenzyl alcohol beta-D-rutinosidePedalitin1-(2,3-dihydroxypropoxy)-3-(((2-(dimethylamino)ethoxy)(hydroxy)phosphoryl)oxy)propan-2-yl (E)-hexadec-9-enoate3,4-Dihydroxybenzoate*1-O-(3,4-Dihydroxy-5-methoxy-benzoyl)-glucosideS-AcetylphosphopantetheineKaempferol 3-sophorotrioside*L-Ascorbic acid-2-glucoside3,6,7-trihydroxy-8-methoxy-2-phenyl-4H-chromen-4-one4,7,9,9'-Tetrahydroxy-3,3'-dimethoxy-8-O-4'-neolignanalpha-D-Glucose 1,6-bisphosphate(+)-Syringaresinol O-beta-D-glucoside*4-caffeoylshikimic acidMethyloxaloacetate1alpha,7beta-Dihydroxykaura-16-ene-18-oic acid2-HydroxypyridineLoganateGuaiacylglycerol-¦Â-Guaiacyl Ether glucosideN-acetyl-tryptophanKayaflavoneTricetin 3'-glucuronide*MyricetindiglucosideConiferinD-XylonateFeruloyltartaric acid (Fertaric acid)trans-Cinnamoyl beta-D-glucoside3-O-Methylellagic acid 4'-sulfate*Dihydroferulic acid glucoside3,5-Dihydroxy-4-methoxybenzoic acid; 4-O-Methylgallic Acid*2-Naphthol*naringenin 5-glucoside*Icariside E5*4'-demethyl-3,9-dihydroeucomin glucoside1-Palmitoyl-Sn-Glycerol 3-O-DiglucosideLitsealactone B1-O-rhamnose-3-O-glucoside-Caffeoyl Quinic Acid4,9-Dihydroxy-17-methoxy-2-oxatricyclo[13.2.2.13,7]icoSa-1(17),3,5,7(20),15,18-hexaen-10-oneEpicatechin-(3'-O-7'')-epiafzelechin2,3-Dihydroamentoflavone 4'''-methyl Ethermethyl alpha-D-fructofuranosideSanguiin H4*1-(2,3-dihydroxypropoxy)-3-(((2-(dimethylamino)ethoxy)(hydroxy)phosphoryl)oxy)propan-2-yl (8E,11Z,14Z)-octadeca-8,11,14-trienoate6,7-dihydroxy-1,3-dimethoxyxanthen-9-onep-Coumaric acid methyl esterOrotate8-(Beta-D-Glucopyranosyloxy)-2,7-Dimethyldec-2-enedioic acid3'-O-methyl-ellagic acid-4-O-beta-D-xylopyranosideEucomic acidGallocatechin gallate*6-HydroxyluteolinSequoiaflavoneEpitheaflavic acid-3'-GallateHomogentisate*Hesperetin2-Acetylphloroglucinol2-ethyl-3-methylbut-2-enedioicacidKankanoside EFicusesquilignan B(-)-Pinoresinol glucoside6-O-p-Coumaroyl-¦Â-D-glucoseAmarantholidoside IV malonatePterosupin(S)-2-Methylmalate2-Aldehydo-A(1)-norlup-20(29)-en-27,28-dioic acid (Zizyberanal acid)Itaconate4-O-Feruloylquinic acid GlucosideLanceolitol B44-Hydroxyphenyl 6-O-(2-Methyl-3-Hydroxypropionyl)-Beta-D-GalactopyranosideQuercetin-3,3'-dimethyl ether9(S)-HODE*Dodecanoic acidCaffeateHydroxydihydrobovolide*Persicarin (Isohamnetin-3-O-sulfate)10-Hydroxydecanoic acidChrysoeriol-7-O-gentiobioside2-hydroxy-3-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propyl octadeca-9,12,15-trienoateBorneol 7-O-[¦Â-D-apiofuranosyl-(1¡ú6)]-¦Â-D-glucopyranoside3'-Hydroxy-4'-methoxy-4'-dehydroxynyasolHyperinalpha-Hydroxylinoleic acid*3-Methylbutyl 6-O-(alpha-L-arabinopyranosyl)-beta-D-glucopyranosidemyo-Inositol 5-phosphate*2-[(1-hydroxy-2-methylpropan-2-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triolMethylgrandiflorosideQuinateMucic acid Dimethyl Ester3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl] 3-hydroxy-4,5-dimethoxybenzoateDihydrodehydrodiconiferyl alcohol-4-O-glucoside*Caffeic acid 4-O-glucoside3,7-Dimethyl-5-Oxo-2,6-Octadien-1-Yl]Beta-D-Glucopyranoside3-Dehydro-L-threonate2-(2-ethoxyethoxy)acetic acid3-(8,11-Heptadecadienyl)-1,2-benzenediolAllantoinEmbelinTheasinensin E*Galloyl-piceidSyringinCatechin gallate*2-Methylsuccinic acid*4-O-Galloylquinic AcidPhosphoenolpyruvateL-Xylose*Taxifolinbeta-Lactose*Apigenin-7-O-glucoside-4'-O-rutinosideBergenincyclic ADP-riboseCatechin-(4¦Á¡ú8)-catechin-(4¦Á¡ú6)-catechinChaenorrhinosideKaempferol-3-O-galactoside (Trifolin)*3-hydroxy-4-[(2r,5s)-5-isopropyl-2-methyloxolan-2-yl]benzoic acid(2R)-2-[(2E)-3-(4-hydroxyphenyl)prop-2-enamido]butanedioic acidCatechin 4'-O-beta-D-glucopyranoside*Carissanol DiglucosideRicinoleic acidKaempferol-xylosyl glucosyl glucosideCupressuflavone6-Hydroxy-4'-O-MethylamentoflavoneD-Mannose*2,6-Dimethoxybenzaldehyde(2S)-1-O-palmitoleyl-3-O-beta-D-galactopyranosylglycerolQuercetin-3,7-Di-O-rhamnosideL-Gulono-1,4-lactone4-HydroxybenzoateMyricitrinShikimate9,10,11-Trihydroxy-12-octadecenoic acidpicrorhizinVanillic acid glucoside2-Dehydro-3-deoxy-L-arabinonatePhaseic acid9-(Arabinosyl)hypoxanthine3-O-Feruloyl Octose*(S)-2-Hydroxyglutarate*Eucalyptin (5-Hydroxy-7,4'-dimethoxy-6,8-dimethylflavone)4-p-Coumaroylquinic acid(+)-Catechin6,9,10-Trihydroxyoctadec-7-enoic acid; Sanleng acidMonogalloyl-diglucose1-(4-Hydroxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diolFumarateD-Glucose 6-phosphate*IsoorientinATP(3S,5R,6R,7E,9S)-megastigm-7-ene-3,5,6,9-tetrol3-(beta-D-glucopyranoside)8-Epiloganic acidCreoside IV4-O-beta-D-Glucosyl-sinapate9-Oxodemethylmyricanane B(2e)-5,7-dihydroxy-2-pentadecylidene-3h-1-benzopyran-4-one5-L-Glutamyl-L-Alanine(2R,3S)-3-Isopropylmalate*AbscisateEllagic acid-4-O-glucosideEriodictyol-8-C-glucoside-4'-O-glucoside5'-Methylbilobetin*SyringetinShikimate 3-phosphate2,4-dihydroxy-6-(15-hydroxyheptadecyl)benzoic acid2,4-Di-Tert-Butylphenol*DGMG 18:2(2n isomer)BilobalideErythro-Guaiacylglycerol-¦Â-Coniferyl EtherCitric Acid glucuronide2-Deoxy-D-ribose 5-phosphate*Dehydroepiandrosterone1-(4-hydroxyphenyl)-3-(2,4,6-trihydroxyphenyl)propan-1-oneRugosic acid AMethyl caffeate2,4-Dinitrophenol(7S,8S-Threo-3',4,7,9-tetrahydroxy-3-methoxy-8-O-4'-neolignan-9'-O-rhamnosideD-Threo-guaiacylglycerol-7-O-¦Â-D-glucoside8-hydroxy-4-(3-hydroxy-4-methoxyphenyl)-5,7-dimethoxychromen-2-oneSuccinate*3-Hydroxy-1-(4'-hydroxy-3'-methoxyphenyl)-propan-1-one(R)-2-Hydroxybutane-1,2,4-tricarboxylateQuercetin-3-O-arabinoglucosideAurantio-obtusin beta-D-glucoside2-O-Galloyl-D-glucose(2S)-5,7,3',5'-tetrahydroxyflavanone-7-O-beta-D-glucopyranoside*Gallocatechin-(4¦Á¡ú8)-epigallocatechin*Ginkgolic Acid (C13:0)Resveratrol2-[3-[4-[1,3-dihydroxy-1-(4-hydroxy-3-methoxyphenyl)propan-2-yl]oxy-3-methoxyphenyl]propoxy]-6-(hydroxymethyl)oxane-3,4,5-triolPhloroglucinol-1-O-¦Â-D-glucopyranosideAbeograndinoic AcidN-Fructosyl Pyroglutamate2,5-Dihydroxybenzoate*Plantaginin2',3,4,4',6'-Peptahydroxychalcone 4'-O-glucoside*FADCornusoside A3-(Hydroxycinnamoyl)-quinic acid*Secoisolariciresinol 4-O-glucoside*2,6-Di-tert-butylphenol*Ferulate*5,2'-Dihydroxy-7-methoxyflavanone3,8-Dimethylherbacetin3'-MethoxypuerarinVanillolosidePhyllanemblinin B*Dihydrotricetin3,3-bis-(4-hydroxy-3-methoxyphenyl)-propane-1,2-diolErythorbic acidMelibiose2-Methylglutaric acid*[(2,3,4,6,7-pentahydroxy-5-oxoheptyl)oxy]phosphonic acidChoerospondin*9,11-dimethoxy-2h-[1,3]dioxolo[4,5-b]xanthen-10-one*3,4,10-trimethylpyrano[3,2-g]chromene-2,6-dioneZizybeoside I*ArbutinN-Acetyl-L-Glutamine1',3,3'-tris-(3-methylbutanoyl)-2-acetyl sucrose6-O-Galloyl-¦Â-D-glucose*Quercetin-4'-O-glucuronide*Myricetin 5-methyl ether 3-O-galactoside4-C-Glucose-1,3,6-trihydroxy-7-methoxyxanthonetrans-3-Hydroxycinnamate*Phellavin3-DehydroquinateEpicatechin-6-C-¦Â-D-glucopyranoside*Morin 3-alpha-L-lyxopyranoside*3-O-p-Coumaroylquinic acidN-AcetylisatinPhthalateCalyxanthone*Kaempferol-3-O-sophorotrioside-7-O-glucosideSalidrosidePicolinic acidD-GlucarateHymenoside M1-O-Caffeoyl-¦Â-D-glucose*Persicosidemyo-Inositolbeta-Maltose*3,4-dihydroxybenzaldehyde-xylose-glucosidep-Coumaroyl-D-glucoseJavanicolide CsachalisideKaempferol triglucoside*Lariciresinol 4,4'-Bis-O-Beta-D-GlucopyranosideGossypetin-8-O-glucosideDihydrophaseic acid-O-¦Â-D-glucoside(2-phenylacetyl)-L-glutamicacid3,3',4,5'-Tetrahydroxybibenzyl(-)-Epigallocatechin3-[(1-Carboxyvinyl)oxy]benzoatePhenyl beta-D-glucopyranoside1,3,6,7-tetrahydroxy-2-(3,4,5-trihydroxyoxan-2-yl)xanthen-9-oneEpicatechin gallate*Naringenin-4'-O-glucoside*Phenyl acetate4,7,10-Hexadecatrienoicacid,(Z,Z,Z)-Lactate1-O-Glucopyranosylamplexine4-Hydroxyphthalate6-((4-(3-hydroxy-2-(4-(3-hydroxypropyl)-2-methylphenoxy)propoxy)-2-methoxyphenoxy)methyl)tetrahydro-2H-pyran-2,3,4,5-tetraol*Cochinolide beta-glucopyranoside3,5-Dihydroxy-7,4'-dimethoxyflavoneVitexin13(S)-HODE*2-Hydroxy-3-(4-Hydroxyphenyl)Propanoic Acid*Chrysophanol-1-O-¦Â-D-glucosidePantetheine8-O-AcetylharpagideGuaiacylglycerol 8-O-(1''-O-Glucosyl)Vanillic Acid Ether5-O-Caffeoylshikimic acid2-[3-hydroxy-5-(hydroxymethyl)phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol3-Aminopropanesulfonate1,8-dihydroxy-2,6-dimethoxy-5-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}xanthen-9-one6¦Â-diydrocormic acidProanthocyanidinsChlorogenate*UDP(-)-Isolariciresinol 4-O-beta-D-glucopyranoside2-(1,3-Dihydroxy-but-2-enylidene)-6-methyl-3-oxo-heptanoic acid2,5-Dihydroxybenzoic acid-5-O-glucoside(2E)-3-{5-[(1E,5E)-2,4-diethylocta-1,5-dien-1-yl]-3,5-diethyl-1,2-dioxolan-3-yl}prop-2-enoic acidD-Glucose 1-phosphate*Methyl 3-O-glucosyl-4-hydroxybenzoate4-O-(3'-O-alpha-D-Glucopyranosyl)caffeoylquinic acidIcariside C1 AcetateKaempferol-3-O-rutinoside-7-O-glucoside*Ellagic acid-4-O-XylosidePhellatinMyricetin-3-O-sulfonatemethyl 2,3,4,5-tetrahydroxypentanoate*LigballinolPhloretate*5,4'-Dihydroxy-3,7-dimethoxyflavone(Kumatakenin)*Chrysoeriol*Homosyringic Acid 4-O-GlucosideLeucocyanidinD-GlucuronolactoneDimethylmalonic acid*RaffinoseResveratrol-3,5-di-O-glucosideAzelaic acidAracarpene 16-DeoxyCatalpolNaringenin-7-O-glucoside (Prunin)*2-(2,3-dihydroxypropoxy)-3-(((2-(dimethylamino)ethoxy)(hydroxy)phosphoryl)oxy)propan-2-yl (E)-hexadec-9-enoate(2Z)-2-hydroxy-3-(4-hydroxyphenyl)prop-2-enoic acidGallate(9Z,11E)-(13S)-13-Hydroperoxyoctadeca-9,11-dienoic acidQuercetin-3-O-glucosyl(1¡ú3)rhamnosyl(1¡ú6)Galactoside12-Hydroxyjasmonic Acid Glucoside5-Hydroxyindoleacetate(R)-2-HydroxyisocaproateRobinlin2-¦Â-D-Glucopyranosyloxy-5-hydroxy-phenylacetic acidPinobanksin 3-O-acetate2,4-dihydroxy-6-[(1e)-2-phenylethenyl]benzoic acid3-(Methoxycarbonyl)propyl-beta-D-glucopyranosideHexadecanedioateHydroxy isoliquiritigenin glucoside*Kaempferol-3-O-rutinoside*LucidinfalsePhotoperiod-mediated transcriptional and metabolic reprogramming confers salt stress tolerance via the ascorbate-glutathione cycle and phenylpropanoid pathway in Ginkgo bilobaGinkgo biloba, one of the oldest extant relict tree species, is highly valued for its medicinal properties. However, soil salinization has emerged as a severe global ecological challenge, substantially restricting plant growth, development, and geographical distribution. While light signaling, particularly photoperiod, is a critical environmental cue, its specific role in the salt stress adaptation of G. biloba remains largely elusive. In this study, we employed a multi-omics approach to analyze the complex mechanisms underlying the responses to salt stress under long-day and short-day conditions. Our results revealed that long-day treatment significantly enhanced salt stress tolerance compared to the short-day condition. Under long-day conditions, plants exhibited significantly higher activities of superoxide dismutase and catalase, which effectively scavenged reactive oxygen species and mitigated membrane lipid peroxidation under salt stress. In parallel, these plants accumulated higher levels of key metabolites such as phenylpropanoids, flavonoids and reduced glutathione. Integrated transcriptomic and metabolomic analyses indicated that the long-day regime mitigates salt stress by coordinately modulating glutathione metabolism, phenylpropanoid biosynthesis, and flavonoid biosynthesis pathways. Crucially, the expression patterns of key biosynthetic genes aligned consistently with the observed accumulation levels of these metabolites. Taken together, these findings demonstrate that long-day conditions enhance salt tolerance in G. biloba by promoting the accumulation of ascorbate-glutathione cycle components and secondary metabolites, thereby strengthening its antioxidant and detoxification capacities. These insights reveal a photoperiod-dependent metabolic reprogramming mechanism, advancing our understanding of how environmental light cues modulate abiotic stress resilience in woody perennial species.2026-07-222026-07-22MTBLS15130Cmsp004086Cmhp002692Cmyp005062Cwjp002051Cmzp002057Cwjp002007Cmxp003531Cmjp002127Cmsp006026Cmsn002067Cmqn010698Cmmn012461Cmqn011321Cmsn002383Cmsn001914Cmqn011996Cmrn001591Cmxn004016Cmrn003275Cmjn004337