MetaboLightsapplication/xmlftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/m_MTBLS15141_LC-MS_positive_hilic_v2_maf.tsvftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/m_MTBLS15141_LC-MS_negative_hilic_v2_maf.tsvftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/a_MTBLS15141_LC-MS_negative_hilic.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/s_MTBLS15141.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/i_Investigation.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/a_MTBLS15141_LC-MS_positive_hilic.txtftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/TZ_2_2.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/TZ_1_3.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/CS_1_2.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/CS_4_2.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/CS_4_1.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/CS_3_3.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/TZ_2_1.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/TZ_2_3.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/CS_1_3.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/CS_4_1.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/TZ_2_2.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/CS_2_1.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/CS_3_2.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/CS_4_3.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/QC2.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/TZ_3_1.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/CS_1_2.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/TZ_2_3.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/CS_4_2.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/TZ_3_1.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/QC1.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/CS_1_1.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/TZ_3_3.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/CS_1_1.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/TZ_3_2.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/CS_4_3.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/TZ_4_1.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/CS_2_2.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/QC4.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/CS_3_1.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/TZ_3_2.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/CS_2_3.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/QC2.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/CS_2_1.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/TZ_3_3.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/CS_1_3.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/TZ_1_1.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/QC3.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/TZ_4_1.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/TZ_4_2.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/QC1.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/TZ_1_1.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/CS_3_3.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/TZ_4_3.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/QC4.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/CS_3_1.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/CS_2_2.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/TZ_4_2.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/CS_3_2.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/TZ_1_2.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/TZ_1_2.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/QC3.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/TZ_2_1.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/CS_2_3.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/POS/TZ_1_3.rawftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141/FILES/RAW_FILES/NEG/TZ_4_3.rawprimaryOK200ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15141<p>Metabolite identification was performed using the PerSonalbio Next-Generation</p><p>Metabolomics Database (PSNGM Database), which includes a self-built standard library, the mzCloud</p><p>library (https://www.mzcloud.org/), LIPID MAPS (https://www.lipidmaps.org/), HMDB (https://hmdb.ca/),</p><p>MoNA (https://mona.fiehnlab.ucdavis.edu/), NIST MSMS, and an AI-predicted MSMS map library.</p><p>The main search parameters were as follows: MS1 tolerance for identification 0.01, MS2 tolerance for</p><p>identification 0.05, smoothing level 3, minimum peak height 10000, minimum peak width 5, mass slice</p><p>width 0.05, and identification score cut-off 70.</p>MetaboLightsPublicLiquid Chromatography MS - positive - hilicLiquid Chromatography MS - negative - hilic<p>Metabolites were separated using a ThermoVanquish Flex chromatograph ( Thermo Fisher Scientific,</p><p>Waltham, MA, USA ) and identified in both positive and negative ion modes using a Thermo Orbitrap</p><p>Exploris 120 mass spectrometer (Thermo Fisher Scientific, Waltham, MA, USA) equipped with a HESI</p><p>source . An ACQUITY UPLC HSS T3 column (100Å, 1.8 µm, 2.1 mm × 100 mm) was used at a flow rate of</p><p>0.4 mL/min , a column temperature of 40°C, an autosampler at 8°C, and an injection volume of 2 μL . The</p><p>mobile phases consisted of 0.1% formic acid in water (mobile phase A) and acetonitrile (containing 0.1%</p><p>formic acid, v/v) (mobile phase B).</p><p>The mobile phase gradient for&nbsp;8.5 min&nbsp;on the machine is as follows: 0-1 min, 5% B; 1-4.7 min, 5%-95%</p><p>B; 4.7-6 min, 95% B; 6-6.1 min, 95%-5% B; 6.1 min-8.5 min, 5% B.</p><p>The mobile phase gradient for&nbsp;12 min&nbsp;on the machine is as follows: 0-1 min, 5% B; 1-7 min, 5%-95%</p><p>B; 7-8 min, 95% B; 8-8.1 min, 95%-5% B; 8.1 min-12 min, 5% B</p>Microbiome-metabolome reveals rhizosphere ecology, bioactives and antioxidant shifts in Paeonia lactiflora Pall under intercropping and harvest periods.Jinggangshan UniversityCheng Jingrootmass spectrometry assay<p>40 mg of the ground plant sample ( 10 mg of dried, lyophilized, or lyophilized powdered plant sample )</p><p>into a 2 mL centrifuge tube ;</p><p>Add 300 μL of pre-cooled methanol:acetonitrile :water ( 2:2 :1, v/ v/v , containing 5 ppm 2-</p><p>chlorophenylalanine) , add 2 steel balls, and vortex for 30 s ;</p><p>Place in a high-throughput tissue homogenizer, homogenize at 55 Hz for 60 s, and repeat this step once;</p><p>Place in an ultrasonic cleaner and sonicate for 10 minutes.</p><p>Freeze in a -20°C freezer for 30 minutes;</p><p>Centrifuge at 12,000 rpm and 4℃ for 10 min, take the supernatant and filter it through a 0.22 μm filter</p><p>membrane, and add the filtrate to the test bottle ;</p><p>Take 10-20 μL of each sample filtrate and mix them to form a QC sample . No QC is performed for 11</p><p>or fewer samples . This is used to evaluate instrument stability and data reliability.</p>Paeonia lactiflora Pallhttps://www.ebi.ac.uk/metabolights/MTBLS15141Cheng Jing. Jinggangshan University. 2455452884@qq.com.<p>Import the raw data from the analyzer into MS-DIAL software (version 4.9.221218). Peak extraction,</p><p>alignment, filtering, and metabolite identification are then performed using this software. Compounds with</p><p>more than 50% deletion within each group are filtered out , and undetected peaks are filled with missing</p><p>values and normalized.</p>Treatment2455452884@qq.com<p>Samples were collected from the root of medicinal&nbsp;Paeonia lactiflora&nbsp;(white peony) grown under different cropping patterns and harvested at different stages in Jinggangshan City, Jiangxi Province, China, in September 2025. Two cropping treatments were established: intercropping (peony–tea plant intercropping system, designated as TZ) and monocropping (designated as CS), each with three biological replicates. Sampling was performed every 20 days starting from September 2025, at four time points, yielding samples designated as TZ-1/CS-1, TZ-2/CS-2, TZ-3/CS-3, and TZ-4/CS-4, respectively. Each sample comprised three replicates (e.g., TZ-1-1, TZ-1-2, TZ-1-3, and so forth). At each sampling time point, three healthy&nbsp;P. lactiflora&nbsp;plants with uniform growth were randomly selected. The root surface soil was removed, and the roots were thoroughly washed with distilled water and blotted dry. After drying, the roots were cut into 1-cm segments, ground into a fine powder in liquid nitrogen, transferred into cryovials, and stored at −80°C for subsequent metabolomic analysis.</p>MetabolomicsMetabolomicsuntargeted analysisThermo Scientific Vanquish Flex UHPLC SystemThermo Scientific Orbitrap Exploris 120Paeonia lactiflora PallrootActive IngredientPaeonia lactiflora Pall (P. lactiflora)experimental blankantioxidant activitymicrobiomeuntargeted metabolite profilingMetabolomicsuntargeted analysisThermo Scientific Vanquish Flex UHPLC SystemThermo Scientific Orbitrap Exploris 120Paeonia lactiflora PallrootActive IngredientPaeonia lactiflora Pall (P. lactiflora)experimental blankmicrobiomeantioxidant activityuntargeted metabolite profiling<p>The mass spectrometer parameters were as follows: spray voltage&nbsp;3.5 kV/-3.0 kV, sheath gas 40 arb,</p><p>auxiliary gas 10 arb, capillary temperature 320°C, auxiliary gas temperature 300°C, primary resolution</p><p>60,000, scan range 70–1000 m/z, AGC Target Standard, Max IT 100 ms, screening of the&nbsp;top 4 ions&nbsp;for</p><p>secondary fragmentation, dynamic exclusion time 4 s, secondary resolution 15,000, HCD collision energy</p><p>30%, AGC Target Standard, Max IT Auto</p>Benzoic acidTaurineCorchorifatty acid FPA(18:3(9Z,12Z,15Z)/0:0)NaringeninGentianoseProcyanidin B1Oleanolic acidVerbenalinConiferyl alcoholbeta-hydroxylauric acidEllagic acidD-(+)-Glucose3,5-dihydroxybenzoic acidEthyl gallateD-PANTOTHENIC ACID3,5-Dihydroxy-4-methoxybenzoic acidKaempferol-3-O-beta-glucopyranosyl-7-O-alpha-rhamnopyranosidePhosphoric acidD-(-)-Quinic acid2-Isopropylmalic acidAcetylsalvipisonecarglumic acidScopoletinDibenzyl disulfideCamphoric Acid, (+)-Ribonolactonebeta-D-Ethyl glucuronide5-MethoxypsoralenProcyanidin B33-[(Carboxycarbonyl)amino]-L-alanine2-Oxoglutaric acid9-HODESwerosideHomovanillic acid sulfateMaslinic acid1-O-Sinapoyl-beta-D-glucosetrans-Aconitic acidHyperosidePyruvic acidNaringin dihydrochalcone(-)-3-dehydroshikimic acidUridine diphosphategalactoseSalidrosideD-MannitolKutkoside1-(9Z,12Z-Octadecadienoyl)-2-hydroxy-sn-glycero-3-phosphoethanolamineGlycolic acid1,2,3,6-tetragalloylglucoseAstragalinL-TryptophanEriodictyolXylobioseD-MannoheptuloseharpagideIsomaltose2-Hydroxypalmitic AcidGlutarateDiacetylCitric acidOxypaeoniflorinNorgestrelIsoferulic acid(-)-Epigallocatechin GallateMYO-INOSITOLNovobiocinPE(16:0/0:0)HexoseGlyceraldehyde3-Hydroxydecanoic acidPMPACreatine3-hydroxyhexadecanoic acidD-(-)-ErythroseSyringateVanillic acidN-MethylhydantoinStachyoseD-Glucose 6-phosphateHexadecanedioic acidGLUCONIC ACIDL-SORBOSELoganinPimpinellindihydrocitrinoneL-Malic acidCyanuric acidGeniposideswertiamarinAcuminosideOxalic acid2-Methylcitric acidSuccinic acidOxypurinolOrnithineMarein(R)-3-Hydroxy myristic acid4-Dodecylbenzenesulfonic acidMaleic AcidRaffinoseD-AlloseAzelaic acidHamamelitanninThioacetic acidL-2-Hydroxyglutaric acid(+/-)9-HpODEDihydrocaffeic acid1-palmitoyl-2-oleoyl-sn-glycero-3-phosphateNystoseAurantio-obtusinCatechinTREHALOSEMonoethyl phthalateEnoxacinCatalpolMoclobemide2,5-Furandicarboxylic acidFructoseSACCHARATEMethylglyoxalBenzoylpaeoniflorinAceglutamideL-SerineLactic acidfalseMicrobiome-metabolome reveals rhizosphere ecology, bioactives and antioxidant shifts in Paeonia lactiflora Pall under intercropping and harvest periodsPaeonia lactiflora Pall (P. lactiflora) is a plant with medicinal and economic value; during its growth, root secondary metabolism and rhizosphere microbes interact, but no systematic study has examined microbiome and metabolome changes under different planting and harvest times; to address this, we used amplicon sequencing for microbial diversity and untargeted metabolomics for metabolite profiling, then integrated and correlated the datasets. We measured paeoniflorin (PC) by HPLC, total phenolic content (TPC) by the Folin-Ciocalteu method, total flavonoid content (TFC) by the NaNO2-Al(NO3)3 method, and antioxidant activity by DPPH, ABTS, hydroxyl radical scavenging, and FRAP assays. From bacterial results, Proteobacteria was the dominant phylum, and Subgroup_2 was the most abundant genus; for fungi, Ascomycota dominated, and Coniosporium was the top genus. Metabolomic PCA separated all treatment groups, and we identified 447, 471, 493, and 453 differential metabolites from four pairwise comparisons, including lipids, phenylpropanoids, polyketides, and benzenoids. Enrichment analysis indicated these differences were mostly related to amino acid metabolism, secondary metabolite biosynthesis, and ABC transporter pathways. Notably, CS-4 had higher PC, TPC, and TFC, and also stronger radical-scavenging activity than other groups. Overall, our findings suggest planting pattern and harvest time both affect plant phenotype and metabolic profiles, providing a solid theoretical basis for improving cultivation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