Metabolite identification was performed using the PerSonalbio Next-Generation Metabolomics Database (PSNGM Database), which includes a self-built standard library, the mzCloud library (https://www.mzcloud.org/), LIPID MAPS (https://www.lipidmaps.org/), HMDB (https://hmdb.ca/), MoNA (https://mona.fiehnlab.ucdavis.edu/), NIST_2020_MSMS, and an AI-predicted MSMS map library. The main search parameters were as follows: MS1 tolerance for identification 0.01, MS2 tolerance for identification 0.05, smoothing level 3, minimum peak height 10000, minimum peak width 5, mass slice width 0.05, and identification score cut-off 70.
"],"repository":["MetaboLights"],"study_status":["Public"],"ptm_modification":[""],"instrument_platform":["Liquid Chromatography MS - negative - reversed-phase-chromatography","Liquid Chromatography MS - positive - reversed-phase-chromatography"],"chromatography_protocol":["Metabolites were separated using a ThermoVanquish Flex chromatograph ( Thermo Fisher Scientific, Waltham, MA, USA ) and identified in both positive and negative ion modes using a Thermo Orbitrap Exploris 120 mass spectrometer (Thermo Fisher Scientific, Waltham, MA, USA) equipped with a HESI source . An ACQUITY UPLC HSS T3 column (100Å, 1.8 µm, 2.1 mm × 100 mm) was used at a flow rate of 0.4 mL/min , a column temperature of 40°C, an autosampler at 8°C, and an injection volume of 2 μL . The mobile phases consisted of 0.1% formic acid in water (mobile phase A) and acetonitrile (containing 0.1% formic acid, v/v) (mobile phase B). The mobile phase gradient for 8.5 min on the machine is as follows: 0-1 min, 5% B; 1-4.7 min, 5%-95% B; 4.7-6 min, 95% B; 6-6.1 min, 95%-5% B; 6.1 min-8.5 min, 5% B. The mobile phase gradient for 12 min on the machine is as follows: 0-1 min, 5% B; 1-7 min, 5%-95% B; 7-8 min, 95% B; 8-8.1 min, 95%-5% B; 8.1 min-12 min, 5% B .
"],"publication":["Tryptophan Metabolism and AHR Signaling in the Intraocular Fluid of Uveitis: An Exploratory Study Integrating Metabolomics, Single-Cell Transcriptomics, Molecular Docking, and Mendelian Randomization within a Gut–Eye Axis Framework."],"submitter_name":["luo qiulin"],"submitter_affiliation":["The Affiliated Hospital of Yunnan University"],"organism_part":["vitreous humor"],"technology_type":["mass spectrometry assay"],"disease":[""],"extraction_protocol":["Transfer 50 μL of sample into a 2 mL centrifuge tube ; Add 200 μL of pre-cooled methanol:acetonitrile (1:1, v/v) , vortex for 30 s ; 10. Freeze in a-20°C freezer for 30 minutes; Centrifuge at 2,000 rpm and 4℃ for 10 min, and take 200 μL of the supernatant and concentrate it under vacuum until dry . Redissolve in 150 μL of 50 % methanol ( containing 5 ppm 2- chlorophenylalanine ) and vortex for 30s ; Centrifuge at 12,000 rpm and 4℃ for 10 min, take the supernatant and filter it through a 0.22 μm filter membrane, and add the filtrate to the test bottle ; Take 10-20 μL of each sample filtrate and mix them to form a QC sample , This is used to evaluate instrument stability and data reliability .
"],"organism":["Homo sapiens"],"full_dataset_link":["https://www.ebi.ac.uk/metabolights/MTBLS15487"],"author":["Qiulin Luo. The Affiliated Hospital of Yunnan University (The Second People's Hospital of Yunnan Province). 18313956584@163.com.","Wenli Yuan. The Affiliated Hospital of Yunnan University (The Second People's Hospital of Yunnan Province). yuanwenli1018@126.com.","Kangwei Jiao. The Affiliated Hospital of Yunnan University (The Second People's Hospital of Yunnan Province). Kangweijiao@hotmail.com."],"data_transformation_protocol":["Import the raw data from the analyzer into MS-DIAL software (version 4.9.221218). Peak extraction, alignment, filtering, and metabolite identification are then performed using this software. Compounds with more than 50% deletion within each group are filtered out , and undetected peaks are filled with missing values and normalized.
"],"study_factor":["Group"],"submitter_email":["18313956584@163.com"],"sample_collection_protocol":["Undiluted intraocular vitreous fluid was obtained during surgical procedures. Fresh vitreous humor samples were immediately placed into pre_chilled cryovials after collection, snap_frozen in liquid nitrogen, and stored at _80 °C until metabolite extraction. Repeated freeze_thaw cycles were strictly avoided.
"],"omics_type":["Metabolomics"],"study_design":["Metabolomics","Thermo Orbitrap Exploris 120","tryptophan metabolism","untargeted analysis","Homo sapiens","vitreous humor","uveitis","indole-3-lactic acid","Thermo Vanquish Flex"],"curator_keywords":["Metabolomics","Thermo Orbitrap Exploris 120","tryptophan metabolism","untargeted analysis","Homo sapiens","vitreous humor","uveitis","indole-3-lactic acid","Thermo Vanquish Flex"],"mass_spectrometry_protocol":["The mass spectrometer parameters were as follows: spray voltage 3.5 kV/-3.0 kV, sheath gas 40 arb, auxiliary gas 10 arb, capillary temperature 320°C, auxiliary gas temperature 300°C, primary resolution 60,000, scan range 70–1000 m/z, AGC Target Standard, Max IT 100 ms, screening of the top 4 ions for secondary fragmentation, dynamic exclusion time 4 s, secondary resolution 15,000, HCD collision energy 30%, AGCTarget Standard, Max IT Auto.
"],"metabolite_name":["Glycochenodeoxycholic Acid-3-O-beta-glucuronide","3-carboxy-4-methyl-5-pentyl-2-furanpropanoic acid","2-Aminonicotinic acid","2-Chloro-L-alanine","Neurokinin-1 Receptor Antagonist","Humulinic acid A","Augustamine","Streptidine","C75 trans","Urolithin B","2-(Ethoxymethyl)-1h-Imidazo[4,5-C]quinolin-4-Amine","Tridecanoylglycine","3-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]-dihydrofuran-2-one","Lumirubin","8-Amino-7-oxononanoic acid","1-Naphthalenesulfonyl chloride","5-((7-(Benzyloxy)quinazolin-4-yl)amino)-4-fluoro-2-methylphenol","alpha-(Dimethylaminomethyl)-2-(3-ethyl-5-methyl-4-isoxazolyl)-1H-indole-3-methanol","4-Allylphenol sulfate","hydroxyoxazolone","5,7-Dihydroxy-3-methoxyflavone","Kamolonol","5-Hydroxyindole-3-acetic acid","Oxoglutaric acid","N-Nonanoylglycine","2,5-Dihydroxybenzenesulfonic Acid","Scopoletin","4-Oxoproline","4-[(S)-Amino(carboxy)methyl]-3-methylbenzoic acid","3-Hydroxy-6,8-dimethoxy-7(11)-eremophilen-12,8-olide","3-Hydroxy-3-methylglutarate","(3S)-4-[[(1S)-1-Carboxy-2-phenylethyl]amino]-3-[8-(diaminomethylideneamino)octanoylamino]-4-oxobutanoic acid","Calystegine A7","3-Hydroxydodecanoic acid","2,4-Dichlorophenoxyacetic acid","1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine","4,6-Dichloropyrimidine-5-carboxylic acid","2,2-Methylenebis(4-ethyl-6-tert-butylphenol)","Methyltrienolone","Pyruvic acid","1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine","Pyrroline hydroxycarboxylic acid","4-Ethylphenylsulfate","Glycolic acid","L-Tryptophan","Monoisobutyl phthalic acid","2H-Pyran-2-one, tetrahydro-4-hydroxy-4-methyl-, (R)-","6-Methylquinoline","3,5-Dimethoxy-2,7-phenanthrenediol","INDOLE-2-ACETIC ACID","(8E,15E)-1,8,15-Heptadecatriene-11,13-diyne","Dihydrolipoate","2-Hydroxypalmitic Acid","Tofisopam","Pseudouridine","Cyheptamide","URIC ACID","2,3-Dihydro-2,3-dihydroxy-4-(4-hydroxyphenyl)-1H-phenalen-1-one","Nitazoxanide","7-hydroxyolanzapine","Mepyramine","(S)-2-Hydroxy-3-phenylpropanoic acid","2,3,5,6-Tetrafluorobenzenethiol","N-Acetyl-L-methionine","Diphenyl sulfone","3-Hydroxydecanoic acid","Allyl chloride","2-Amino-3,7,8-trimethylimidazo(4,5-f)quinoxaline","16beta-OH-Dhea sulfate","Malonic semialdehyde","14-Fluoro-6-thiaheptadecanoic acid","1,4-Bisdesoxycyadox","Isopropyl 4-hydroxybenzoate","epiandrosterone sulfate","Decanedioic acid","GlycolithoCholic acid-3-Sulfate","Busulfan","Indoleacrylic acid","4-oxo-4-(3-pyridyl)butanoic acid","Hexadecanedioic acid","trans-4-[4-(4-Amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexaneacetic acid","Phthalic acid","(S)-3-Hydroxyisobutyric acid","Biliverdin","Brassylic acid","Homocitric acid","Cyanuric acid","Oxalic acid","Quisqualic acid","5-Sulfosalicylic acid","Succinic acid","Bis(2-ethylhexyl) hydrogen phosphate","2-(5-Hydroxy-1H-indol-2-yl)acetic acid","Adipic acid","2,4-Dinitrophenol","3-oxovaleric acid","4-Dodecylbenzenesulfonic acid","5-Hydroxyisourate","2,3-Epoxymenaquinone","Myricanone","Testosterone sulfate","Codeine N-oxide","1,3-Dithiole-2-thione","3-(4-(2-Dimethylamino-1-methylethoxy)phenyl)-1H-pyrazolo(3,4-b)pyridine-1-acetic acid","Diacetoxyscirpenol","Gamma-delta-Dioxovaleric acid","(E)-Ethyl caffeate","1,2-Dichloroethane","Inositol trisphosphate","L-Ascorbic acid","P-cresyl sulfate","Isolysergol","20-HDoHE","2-Methylhippuric acid","Asp-Gln","1-Carboxyethylleucine","Threonic acid","1,3-Diacetylbenzene","Cyclamate","beta-CCM","Carboxyibuprofen","4-O-Methylgallic acid","ALLOSE","7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, N-oxide","N-Acetylcyanamide","Benzoic acid","Emopamil","Palmitoylglycine","2-Fluorobutyl 2-(8-azabicyclo[3.2.1]octan-1-yl)-5-iodobenzoate","Tetradecanedioic acid","Methyl 2-hydroxy-4-methylvalerate","(8R,9S,13S,14S)-3-Hydroxy-13-methyl-4,6,7,8,9,11,12,14,15,16-decahydro-3H-cyclopenta[a]phenanthren-17-one","2,4-Dinitroanisole","Dodecyl gallate","Ethyl isothiocyanate","Gamma-Hydroxybutyric acid","INDOXYL SULFATE","1,2,4-Trichlorobenzene","Cuprizone","Eglumetad","Veliparib","2-Hydroxyundecanoate","D-(+)-Glucose","3,5-Dichloro-2,6-dihydroxybenzoic acid","Yuccagenin","Cyanoacetic acid","Myrmicacin","kainic acid","curcumin II","O-glutaroyl-L-carnitine","Nitrosyl acetate","N-Undecanoylglycine","Diferuloylputrescine","Vanillylmandelic acid","3-[[(2S)-3-(4-Phenylphenyl)-2-(phosphonomethylamino)propanoyl]amino]propanoic acid","N-acetyl-L-2-aminoadipate(2-)","(S)-3,4-Dihydroxybutyric acid","N-Formylanthranilic acid","Aminohydroxyacetic acid","N-Lactoylleucine","3-hydroxypentadecanoic acid","Suberic acid","PA(2:0/22:6(4Z,8Z,10Z,13Z,16Z,19Z)-OH(7))","Acetylenedicarboxylic acid","6-Gingerol","Penoxsulam","(-)-3-dehydroshikimic acid","Picolinic acid","4-Nitrophenol","Hydroxyacetone","L-Threonic acid-1,4-lactone","(+/-)-3-Hydroxynonanoic acid","15-acetyldeoxynivalenol","(2E)-2-{6-[(E)-2-Carboxyethenyl]-2,3-dihydroxyphenyl}-3-(3,4-dihydroxyphenyl)prop-2-enoic acid","Malabaricone B","3-Hydroxyoctanoic acid","1-(9H-Pyrido[3,4-b]indol-1-yl)-1,4-butanediol","Sodium dodecanoate","Jurubine","Melengestrol","L-(+)-Leucic Acid","Hydroxyphenyllactic acid","2-O-Methylascorbic acid","N-Lactoylphenylalanine","Salicylic acid","Hydroxymethyl hydrogen carbonate","Dodecanedioic acid","cis-Acetylacrylate","cis-4-Octenedioic acid","Isomaltose","5-Hydroxyhexadecanoic acid","14,19-Didehydrocondyfolan","Citric acid","4,10-Longipinanedione","Norgestrel","3-Hydroxyhexadecanoic acid","Bicyclo prostaglandin E2","L-(-)-Phenylalanine","LysoPG(16:0/0:0)","Beta-D-Fructose 2-phosphate","N-Decanoylglycine","INDOLELACTIC ACID","(S)-Laudanosine","METHYLSUCCINIC ACID","Dibutyl phthalate","Glyoxalic acid","Tauroursodeoxycholic acid","Bilirubin","Glyphosate","1-(Difluoromethyl)-2,3,4-trifluorobenzene","Zingerone","3-Hydroxysebacic acid","(8R,9R,10S,13S,14S)-13-Methyl-1,4,5,6,7,8,9,10,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene","3-(Hydroxymethyl)-5-oxopentanoic acid","2-hydroxyacrylic Acid","Tetradecyl sulfate","N-Methylhydantoin","Zymonic acid","3-Methoxyphenol sulfate","Norethindrone acetate","Lomerizine","sorbitol lactate","1-Carboxyethyltyrosine","3-Amino-4-methylpentanoic acid","DIMBOA trihexose","2-Aminothiazole","2-Hydroxy-3-methylbutyric acid","3-hydroxytridecanoic acid","D-(+)-Galactose","4-O-Methylmelleolide","Nonate","1,1-Dichloroethane","Undecanedioic acid","10-(Phosphonooxy)decyl methacrylate","N-Acetyl-L-aspartic acid","Dehydroascorbic acid","(12S,15S)-15-O-Demethyl-10,29-dideoxy-11,12-dihydro-striatin C","2-Hydroxy-2-methylbutyric acid","(+/-)-Phyllodulcin","Acetaminophen glucuronide","alpha-ketoadipic acid","chrysoeriol 6-hexoside (use chrysoeriol_6_glucoside.mol)","(R)-3-Hydroxy myristic acid","2-Amino-3,4,8-trimethyl-3H-imidazo[4,5-f]quinoxaline","Hexafluoroisopropanol","Chaetoglobosin N","(2S)-2-(3,8-Dimethylazulen-5-yl)propanoic acid","8-Hydroxy-2-methoxy-6-methyl-1,4-naphthoquinone","Hydrocortisone","2-Hydroxy-3-morpholinopropanesulfonic Acid","Citramalic acid","Dihydrothymine","Azelaic acid","Methylpyrogallol sulfate 1","Allopurinol riboside","2,2'-Methylenebis(4-methyl-6-tert-butylphenol)","Camalexin","2-Carboxy-4-dodecanolide","LTD4","-Muricholic Acid","2-Methylpropyl phenylacetate","1-Palmitoyl-sn-glycero-3-phosphocholine","(6beta,7alpha,12beta,13beta)-7-Hydroxy-11,16-dioxo-8,14-apianadien-22,6-olide","Didesmethylsibutramine","2-Methoxy-N-(1-phenethylpiperidin-4-yl)-N-phenylacetamide","2-[(2R)-2-Aminopropyl]-5-hydroxybenzoic acid","Olomoucine","1-Propanol, 3,3,3-trichloro-","Traumatic Acid","1H-Imidazo[1,2-b]pyrazole","Bergapten","Thiophene-4,5-epoxide","Ethyl 2-phenyl-3-furancarboxylate","3,5-Dichlorophenyl methyl sulphone","Deoxycholic acid","5-Hydroxy Diclofenac","Methyl 4-phenylbutanoate","5-Hydroxy-6-methoxy-1h-indole-2-carboxylic acid","Mitotane","Glycodeoxycholic acid","5-Hydroxy-L-tryptophan","Estrone","Lactic acid","N-Acetylalanine","bis(Benzyloxy)methane","Valylglutamic acid","Phenyl sulfate","CMPF"],"additional_accession":[]},"is_claimable":false,"name":"Tryptophan Metabolism and AHR Signaling in the Intraocular Fluid of Uveitis: An Exploratory Study Integrating Metabolomics, Single-Cell Transcriptomics, Molecular Docking, and Mendelian Randomization within a Gut–Eye Axis Framework","description":"Uveitis is a highly heterogeneous intraocular inflammatory disease, and recurrent attacks can lead to irreversible visual impairment. Gut microbiota may contribute to its pathogenesis through metabolic products and immune modulation, but existing evidence is largely derived from cross-sectional associations, leaving the causal direction unclear. This study investigated the potential involvement of the tryptophan metabolism-aryl hydrocarbon receptor (AHR) signaling axis in uveitis within a gut-eye axis framework, integrating evidence at four levels: metabolic, structural, cellular, and genetic.","dates":{"publication":"2026-08-28","submission":"2026-08-28"},"accession":"MTBLS15487","cross_references":{"HMDB":["HMDB0000517","HMDB0246350","HMDB0000696","HMDB0006344","HMDB0250769","HMDB0032358","HMDB0000158","HMDB0000651","HMDB0000201","HMDB0000791","HMDB0000756","HMDB0002013","HMDB0000062","HMDB0037942","HMDB0246326","HMDB0000824","HMDB0001921","HMDB0000064","HMDB0000594","HMDB0244507","HMDB0000684","HMDB0004825","HMDB0259275","HMDB0062735","HMDB0013128","HMDB0000641","HMDB0000182","HMDB0011171","HMDB0000925","HMDB0061115","HMDB0061189","HMDB0251526","HMDB0013839","HMDB0000258","HMDB0000043","HMDB0061859","HMDB0014494","HMDB0000301","HMDB0000068","HMDB0000148","HMDB0001929","HMDB0029540","HMDB0000162","HMDB0251169","HMDB0000883","HMDB0251527","HMDB0031702","HMDB0000562","HMDB0001046","HMDB0000138","HMDB0062225","HMDB0034587","HMDB0001932","HMDB0000210","HMDB0240689","HMDB0001065","HMDB0000097","HMDB0011718","HMDB0006029","HMDB0246429","HMDB0002250","HMDB0240780","HMDB0000637","HMDB0034159","HMDB0259193","HMDB0005065","HMDB0001859","HMDB0041878","HMDB0001860","HMDB0014426","HMDB0014947","HMDB0015503","HMDB0240783","HMDB0012458","HMDB0244166","HMDB0008043","HMDB0029134","HMDB0014441","HMDB0008100","HMDB0000161","HMDB0002815","HMDB0001200","HMDB0000294","HMDB0001406","HMDB0000157","HMDB0251245","HMDB0249149","HMDB0000715","HMDB0251174","HMDB0253028","HMDB0015654","HMDB0061822","HMDB0034301","HMDB0256280","HMDB0040045","HMDB0001161","HMDB0008039","HMDB0011749","HMDB0258626","HMDB0003243","HMDB0245344","HMDB0007991","HMDB0251214","HMDB0002825","HMDB0010169","HMDB0031641","HMDB0001889","HMDB0000423","HMDB0245813","HMDB0000549","HMDB0029737","HMDB0000564","HMDB0010384","HMDB0059876","HMDB0003073","HMDB0304941","HMDB0008057","HMDB0029559","HMDB0244898","HMDB0000050","HMDB0031342","HMDB0001847","HMDB0002322","HMDB0252495","HMDB0000252","HMDB0000086","HMDB0249001","HMDB0004610","HMDB0000271","HMDB0254979","HMDB0062656","HMDB0245112","HMDB0004193","HMDB0002117","HMDB0034292","HMDB0029599","HMDB0251189","HMDB0000112","HMDB0000030","HMDB0251319","HMDB0000827","HMDB0251571","HMDB0003681","HMDB0257910","HMDB0014730","HMDB0015095","HMDB0002088","HMDB0240552","HMDB0011262","HMDB0004240","HMDB0000195","HMDB0246938","HMDB0000220","HMDB0060997","HMDB0245345","HMDB0038462","HMDB0004363","HMDB0251144","HMDB0031404","HMDB0243945","HMDB0040915","HMDB0014850","HMDB0258579","HMDB0245220","HMDB0000462","HMDB0014954","HMDB0001173","HMDB0254682","HMDB0245970","HMDB0248974","HMDB0242431","HMDB0012273","HMDB0256982","HMDB0251156","HMDB0061875","HMDB0242481","HMDB0243567","HMDB0250209","HMDB0006406","HMDB0243795","HMDB0012107","HMDB0256217","HMDB0012252","HMDB0258202","HMDB0002994","HMDB0015197","HMDB0039780","HMDB0252498","HMDB0247976","HMDB0000429","HMDB0032055","HMDB0259770","HMDB0034690","HMDB0003626","HMDB0060065","HMDB0031540","HMDB0241067","HMDB0032567","HMDB0240752","HMDB0000403","HMDB0012275","HMDB0254998","HMDB0001427","HMDB0301805","HMDB0246585","HMDB0251557","HMDB0037844","HMDB0244918","HMDB0240779","HMDB0061165","HMDB0247472","HMDB0002428","HMDB0000015","HMDB0247556","HMDB0061384","HMDB0004705","HMDB0013654","HMDB0030967","HMDB0029852","HMDB0259191","HMDB0260290","HMDB0060550","HMDB0061634","HMDB0244181","HMDB0060959","HMDB0246202","HMDB0256810","HMDB0289581","HMDB0245431","HMDB0031548","HMDB0029455","HMDB0031642","HMDB0032964","HMDB0243985","HMDB0001547","HMDB0252369","HMDB0244259","HMDB0250270","HMDB0033127","HMDB0037593","HMDB0007972","HMDB0304736","HMDB0029449","HMDB0037845","HMDB0039827","HMDB0289743","HMDB0247722","HMDB0062558","HMDB0248559","HMDB0029368","HMDB0008366","HMDB0061699","HMDB0014514","HMDB0240781","HMDB0061131","HMDB0248746","HMDB0155722","HMDB0258432","HMDB0015238","HMDB0038601","HMDB0247463","HMDB0013159","HMDB0241360","HMDB0257511","HMDB0241787","HMDB0242286","HMDB0004620","HMDB0289641","HMDB0032669","HMDB0241658","HMDB0012162","HMDB0251415","HMDB0245258","HMDB0254448","HMDB0033713","HMDB0036940","HMDB0241868","HMDB0060451","HMDB0289655","HMDB0241703","HMDB0259072","HMDB0241472","HMDB0301838","HMDB0244641","HMDB0062236","HMDB0034146","HMDB0259164","HMDB0289759","HMDB0032456","HMDB0062193","HMDB0255826","HMDB0241217","HMDB0035761","HMDB0008097","HMDB0249296","HMDB0028832","HMDB0241494","HMDB0244636","HMDB0010163","HMDB0254641","HMDB0013139","HMDB0246264","HMDB0241375","HMDB0037840","HMDB0244235","HMDB0241096","HMDB0030374","HMDB0244067","HMDB0304236","HMDB0013078","HMDB0015673","HMDB0245294","HMDB0248284","HMDB0243782","HMDB0040380","HMDB0247903","HMDB0257682","HMDB0245176","HMDB0258042","HMDB0246988","HMDB0244047","HMDB0255129","HMDB0014429","HMDB0249119","HMDB0245159","HMDB0257911","HMDB0002053","HMDB0000156","HMDB0242051","HMDB0014857","HMDB0243808","HMDB0039153","HMDB0245815","HMDB0252085","HMDB0036328","HMDB0013318","HMDB0259299","HMDB0245517","HMDB0241821","HMDB0251594","HMDB0244416","HMDB0038638","HMDB0251336","HMDB0241744","HMDB0247110","HMDB0244317","HMDB0244822","HMDB0255980","H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