{"database":"MetaboLights","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Tabular":["ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/m_MTBLS15536_LC-MS_negative_reverse-phase_v2_maf.tsv","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/m_MTBLS15536_LC-MS_positive_reverse-phase_v2_maf.tsv"],"Txt":["ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/s_MTBLS15536.txt","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/a_MTBLS15536_LC-MS_negative_reverse-phase.txt","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/a_MTBLS15536_LC-MS_positive_reverse-phase.txt","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/i_Investigation.txt"],"Raw":["ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/C_NEG_2.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/H_POS_4.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/HCS9_POS_2.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/H_NEG_2.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/C_NEG_6.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/HCS9_POS_6.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/C_POS_4.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/H_NEG_3.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/HCS9_NEG_5.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/HCS9_POS_3.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/C_NEG_1.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/C_POS_3.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/HCS9_POS_5.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/HCS9_NEG_1.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/C_NEG_5.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/H_POS_5.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/H_NEG_1.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/H_NEG_6.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/HCS9_NEG_6.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/H_POS_2.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/HCS9_POS_4.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/C_POS_6.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/C_NEG_4.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/H_POS_6.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/HCS9_NEG_2.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/H_NEG_5.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/C_POS_2.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/H_POS_3.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/C_POS_5.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/H_POS_1.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/HCS9_NEG_3.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/HCS9_POS_1.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/HCS9_NEG_4.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/C_POS_1.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/H_NEG_4.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536/FILES/C_NEG_3.raw"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"ftp_download_link":["ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15536"],"metabolite_identification_protocol":["<p>Metabolite annotation was performed using MS-DIAL (version 4.9.221218) based on the PerSonalbio Next-Generation Metabolomics Database (PSNGM), which integrates an in-house standard library with mzCloud, LIPID MAPS, HMDB, MoNA, NIST 2020 MS/MS, and AI-predicted MS/MS spectral libraries. The main identification parameters were set as follows: MS1 tolerance, 0.01; MS2 tolerance, 0.05; smoothing level, 3; minimum peak height, 10,000; minimum peak width, 5; mass slice width, 0.05; and identification score cutoff, 70. Metabolite identities were assigned based on accurate mass, retention behavior, and MS/MS spectral matching where available.</p>"],"repository":["MetaboLights"],"study_status":["Public"],"ptm_modification":[""],"instrument_platform":["Liquid Chromatography MS - negative - reverse-phase","Liquid Chromatography MS - positive - reverse-phase"],"chromatography_protocol":["<p>Chromatographic separation was performed using a Thermo Vanquish Flex UHPLC system equipped with an ACQUITY UPLC HSS T3 column (100 Å, 1.8 μm, 2.1 × 100 mm). The column temperature was maintained at 40 °C, the autosampler temperature was set at 8 °C, the flow rate was 0.4 mL/min, and the injection volume was 2 μL. For both positive and negative ion modes, mobile phase A consisted of water containing 0.1% formic acid, and mobile phase B consisted of acetonitrile containing 0.1% formic acid. The gradient elution program was as follows: 5% B at 0–1.0 min, increased to 95% B at 4.7 min, maintained at 95% B until 6.0 min, returned to 5% B at 6.1 min, and maintained at 5% B until 8.5 min.</p>"],"publication":["Dietary Cetobacterium somerae LY-01 improves lipid metabolism and intestinal health in largemouth bass (Micropterus salmoides) fed a high-fat diet."],"submitter_name":["Ya-wei wang"],"submitter_affiliation":["Henan normal university"],"organism_part":["Intestinal Content"],"technology_type":["mass spectrometry assay"],"disease":[""],"extraction_protocol":["<p>Approximately 20 mg of each intestinal content sample was placed into a 2 mL centrifuge tube. A total of 300 μL of pre-cooled methanol containing 5 ppm L-2-chlorophenylalanine as an internal standard was added, together with two steel beads. Samples were vortexed for 30 s and homogenized at 55 Hz for 60 s twice, followed by sonication for 10 min. The extracts were incubated at −20 °C for 30 min and then centrifuged at 12,000 rpm for 10 min at 4 °C. The supernatant was collected and filtered through a 0.22 μm membrane prior to LC-MS analysis. A pooled quality-control (QC) sample was prepared by combining 10–20 μL aliquots from each filtered sample and was used to evaluate analytical stability and data quality.</p>"],"organism":["Micropterus salmoides"],"full_dataset_link":["https://www.ebi.ac.uk/metabolights/MTBLS15536"],"author":["Ya-wei wang. Henan normal university. w17637617653@163.com."],"data_transformation_protocol":["<p>Raw LC-MS data files in Thermo .raw format were imported into MS-DIAL (version 4.9.221218) for data processing. The workflow included peak detection, peak alignment, filtering, gap filling of missing values, and normalization. Features not detected in more than 50% of quality-control (QC) samples were removed. Missing values were subsequently filled using the Gap Filling algorithm implemented in MS-DIAL, followed by data normalization to generate the processed feature intensity matrix for downstream analysis.</p>"],"study_factor":["Treatment"],"submitter_email":["w17637617653@163.com"],"sample_collection_protocol":["<p>Largemouth bass (Micropterus salmoides) were subjected to different dietary treatments, including a control diet (C), a high-fat diet (H), and a high-fat diet supplemented with Cetobacterium somerae LY-01 (HCS9). Intestinal contents were collected on June 16, 2025. For each biological replicate, intestinal contents collected from randomly selected fish were pooled to generate one sample. Samples were collected aseptically after dissection, immediately frozen in liquid nitrogen, and stored at −80 °C until untargeted LC-MS metabolomic analysis.</p>"],"omics_type":["Metabolomics"],"study_design":["Metabolomics","Thermo Orbitrap Exploris 120","untargeted metabolomics","Thermo Vanquish Flex UHPLC system","untargeted analysis","high-fat diet","Micropterus salmoides","Intestinal Content","MS-DIAL","intestinal metabolome","largemouth bass","experimental sample"],"curator_keywords":["Metabolomics","Thermo Orbitrap Exploris 120","untargeted metabolomics","Thermo Vanquish Flex UHPLC system","untargeted analysis","high-fat diet","Micropterus salmoides","Intestinal Content","MS-DIAL","intestinal metabolome","largemouth bass","experimental sample"],"mass_spectrometry_protocol":["<p>Mass spectrometric analysis was performed using a Thermo Orbitrap Exploris 120 high-resolution mass spectrometer controlled by Xcalibur software (version 4.7). Data were acquired in negative ion mode using a heated electrospray ionization (HESI) source. The spray voltage was set to −3.0 kV, with sheath gas at 40 arb and auxiliary gas at 10 arb. The capillary temperature was 320 °C and the auxiliary gas heater temperature was 300 °C. Full-scan MS data were acquired over an m/z range of 70–1000 at a resolution of 60,000, with AGC target set to Standard and a maximum injection time of 100 ms. Data-dependent acquisition (DDA) was performed by selecting the top four precursor ions for MS/MS fragmentation. The dynamic exclusion time was 4 s. MS/MS spectra were acquired at a resolution of 15,000 using higher-energy collisional dissociation (HCD) with a collision energy of 30%, an AGC target of Standard, and automatic maximum injection time.</p>"],"metabolite_name":["Soyasapogenol B 3-O-b-D-glucuronide","(10betaH,11xi)-11-Hydroxy-13-nor-6-eremophilen-8-one","Pyocyanin","4-Phenyl-1,2,4-triazoline-3,5-dione","2'-O-Methyluridine","3-Hydroxy-3-carboxymethyl-adipic acid","(3S,8As)-7-hydroxy-3-(hydroxymethyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione","Streptidine","N-Acetyldopamine","Valylglycine","isomaltulose","N-Stearoyl Proline","N-Acetylvaline","L-Histidine","2-Keto-6-acetamidocaproate","Anhydrocinnzeylanine","N-Oleoyl Alanine","Auxin a","2-Naphthalen-1-ylbutanoic acid","coumatetralyl","XANTHURENIC ACID","Dezocine","Scopoletin","()12(13)-DiHOME","2-Ethyl-1-hexanol sulfate","3-Hydroxy-3-methylglutarate","(R)-Bitalin A","Calystegine A7","tetracosahexaenoic acid","PHTHALIC ACID","MG(0:0/LTE4/0:0)","Asebotoxin","PGB2","Propan-2-yl 3-[ethylamino(methoxy)phosphinothioyl]oxybut-2-enoate","Ile-Val-Val","(S)-(+)-1-(p-Hydroxy-trans-cinnamoyl)-glycerol","(2E,8E)-Piperamide-C9:2","Proline-hydroxyproline","Roquefortine C","LysoPE(P-16:0/0:0)","Phe-Pro-Ile","3b,6b-Diangeloyloxy-7(11)-eremophilen-12,8b-olide","L-3-phenyllactic acid","N-Palmitoyl Lysine","Felbinac","N-Palmitoyl Aspartic acid","(6R,8Z)-6-Hydroxy-3-oxotetradecenoic acid","()9(10)-DiHOME","2-Methoxy-3,4-dimethylphenyl acetate","THYMIDINE","N-Acetylglutamic acid","Methionyl-Alanine","N-Arachidonoyl Leucine","Glycitein","N-Eicosapentaenoyl Serine","Caffeic acid","ketomethylvaleric acid","LysoPE(16:1(9Z)/0:0)","Dihydroxyphenylacetic acid sulfate","gamma-Glu-Glu","Ferrioxamine B","Chloropyramine","(S)-N-(4,5-Dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)alanine","isocitric acid","3-Hydroxydodecanedioic acid","4-Pyridoxic acid","p-Tolyl isobutyrate","Glyceraldehyde","N-Acetyl-L-methionine","Allyl chloride","Leu-Val","Glutamylphenylalanine","Cytochalasin A","2-methoxy-hexadecanoic acid","Decanedioic acid","Carboxyfentanyl","Soyasaponin II","Hydroxyprolyl-Tryptophan","N-Palmitoyl GABA","N-Docosahexaenoyl Serine","4-oxo-4-(3-pyridyl)butanoic acid","trans-4-[4-(4-Amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexaneacetic acid","Hexadecanedioic acid","Glycocholenate sulfate","Estradiol 17-sulfate","(1R*,2R*,4R*,8S*)-p-Menthane-1,2,8,9-tetrol 9-glucoside","16alpha-Fluoroestradiol","(1R,7S,13S,15S)-2,15-Dihydroxy-7-methyl-6-oxabicyclo[11.3.0]hexadeca-3,11-dien-5-one","PI(PGJ2/20:1(11Z))","Alanyltyrosine","N-[(6R)-6-(Dimethylamino)-6,7,8,9-tetrahydro-5H-carbazol-3-yl]-4-fluorobenzamide","N-Docosahexaenoyl Leucine","glycochenodeoxycholic acid 7-sulfate","1-Hydroxy-2,2,5,5-tetramethylpyrrolidine-3-carboxylic acid","N-Arachidonoyl Phenylalanine","Uridine","N-Palmitoyl Alanine","Bis(2-ethylhexyl) hydrogen phosphate","1-Carboxyethylphenylalanine","N-Palmitoyl Taurine","Glutamylproline","3-oxovaleric acid","Torvoside G","Austinol","Malonic acid","(1r,3r)-1-Aminocyclopentane-1,3-dicarboxylic acid","Isophthalic acid","N-Linoleoyl Isoleucine","Cymarin","Triterpenoid","4-Formylsalicylic acid","Asn-Val","()19(20)-DiHDPA","NALPHA-ACETYL-L-LYSINE","Famitinib","Glaudine","Ethyl gallate 3-sulfate","Lactamide","LysoPI(16:0/0:0)","2(R)-hydroxydocosanoic acid","LysoPE(20:4(8Z,11Z,14Z,17Z)/0:0)","Codeine N-oxide","Tiaprost","LysoPE(20:5(5Z,8Z,11Z,14Z,17Z)/0:0)","3-(4-(2-Dimethylamino-1-methylethoxy)phenyl)-1H-pyrazolo(3,4-b)pyridine-1-acetic acid","GLYCERIC ACID","Glutaminylarginine","XANTHINE","Gln-Tyr","6-Hydroxypseudooxynicotine","20-HDoHE","-Linolenic acid","N-Palmitoyl tyrosine","Uric acid","Drospirenone","2-Stearamidoacetic Acid","3-Hydroxytetradecanedioic acid","L-galacto-2-Heptulose","Glu-ala","Myrsinone","5-ethyl-5-methyl-2,4-oxazolidinedione","Chrysophanol 8-gentiobioside","4'-Dihydroabscisic acid","Salsolinol-1-carboxylic acid","Valyltyrosine","Oleoyl Glycine","Tyrosyl-Proline","Sulfoacetic acid","Glycylprolylhydroxyproline","N-Acetyl-cysteine","Benzoic acid","3-Hydroxycinnamic acid","Daidzin","Anthra(1,9-cd)pyrazol-6(2H)-one, 2-(2-((2-hydroxyethyl)amino)ethyl)-5-((2-((2-hydroxyethyl)amino)ethyl)amino)-","LysoPE(22:5(7Z,10Z,13Z,16Z,19Z)/0:0)","Ala-Leu","Biotin sulfoxide","Traumatic acid","Guanidinoethyl Sulfonate","Tetradecanedioic acid","gamma-Glutamyltyrosine","O-Acetylserine","Ecabet","3'-O-Methylguanosine","N-Palmitoyl Proline","Levoinositol","taurolithocholic acid sulfate","Eglumetad","(+/-)13-HODE","Albaconazole","Asparagoside B","Pelubiprofen","N-Acetyl-L-tyrosine","Integerrimine","Methoxyacetic acid","N-Palmitoyl Histidine","gamma-Glutamylleucine","LysoPE(20:4(5Z,8Z,11Z,14Z)/0:0)","gamma-Glutamylmethionine","kainic acid","Hydroxytyrosol 3'-sulfate","2-Dodecylbenzenesulfonic acid","N-ACETYL-L-PHENYLALANINE","Acetylsalvipisone","3-hydroxyundecanoyl carnitine","carglumic acid","Pancopride","AdipoRon","N-Undecanoylglycine","N-Acetylanthranilic acid","11,12,15-TriHETRE","Cinnavalininate","7-Hydroxyoctadecanoic acid","Oxindanac","Asp-Met","Humilixanthin","Valsartan","S-Sulfocysteine","Galactonic acid","PGP(18:1(12Z)-2OH(9,10)/i-19:0)","5-Benzylacyclouridine","7-Hydroxyamoxapine","Mammeisin","LysoPE(22:4(7Z,10Z,13Z,16Z)/0:0)","Loperamide oxide","(2S,3R)-3-Hydroxy-2-methylbutanoic acid","2-O-Methylascorbic acid","Stachyflin","Acamprosate","RAFFINOSE","Xanthosine","[(2S)-2-Amino-3-(1H-imidazol-5-yl)propanoyl] (2S,3S)-2-amino-3-methylpentanoate","Safynol","val-phe","3-N-Methylspiperone","Monoketocholic acid","Norgestrel","Cynaroside","N-Acetylleucine","4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl Chloride","(2R,3R,6S)-4-Methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.02,6.06,10.015,19]icosa-1(20),4,13,15(19)-tetraen-3-ol","N-ACETYLTRYPTOPHAN","Leucyl-Tyrosine","Tanacetol A","Sulfoglycolithocholate(2-)","1-oleoyl-sn-glycero-3-phosphoglycerol","INDOLELACTIC ACID","3,4-Dehydrocilostazol","D-()-Erythrose","LysoPE(20:2(11Z,14Z)/0:0)","Medicagenic acid","tectoridin","Levonantradol","4-Androsten-3beta,17beta-diol 17-sulfate","schaftoside","Monatepil","gamma-Glutamylvaline","(-)-Pyrifolidine","cholesteryl sulfate","Tetraazacyclododecanetetraacetic acid","Methyl neopentyl phthalic acid","Abeado","N-Palmitoyl Valine","(5R)-5-[(1S)-1,2-Dihydroxyethyl]-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxolane-2,4-dione","N-Methylhydantoin","Stachyose","Flavan-3-ol","N-[(3a,5b,7a,12a)-3,12-dihydroxy-24-oxo-7-(sulfooxy)cholan-24-yl]-Glycine","(1E)-1-(4-Hydroxy-3-methoxyphenyl)-7-phenyl-1-hepten-3-one","gamma-Glutamylacetamide","Norethindrone acetate","Capsicoside A1","4-Acetamidobutanoic acid","18-HEPE","Sinalbin B","L-SORBOSE","Floionolic acid","3alpha-Hydroxyoreadone","1,1-Dichloroethane","N-Undecylbenzenesulfonic acid","Norbinaltorphimine","Vulgarin","LysoPE(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)","Tanespimycin","apigenin 7-glucuronide","Lumiflavin","Proline glutamate","12-O-D-Glucuronoside-13-hydroxyoctadec-9Z-enoate","2-Methylcitric acid","BENPERIDOL","MES","Monobutyl phthalate","N-Docosahexaenoyl Proline","(2S)-2-(3,8-Dimethylazulen-5-yl)propanoic acid","PI(16:0/18:0)","Cholylisoleucine","11'-Carboxy-gamma-tocotrienol","N-Stearoyltaurine","N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-3,5-dimethoxyaniline","Pyridone 6","()-Ribaline","Nafamostat","10-Hydroxydecanoic acid","1,3,11(13)-Eudesmatrien-12-oic acid","Lumateperone","6-trans-Leukotriene B4","4-Phenyl-1H,3H-naphtho[1,8-cd]pyran-1,3-dione","Glycochenodeoxycholic acid","N-Stearoyl Aspartic acid","Tolnaftate","[2-Amino-2-(hydroxymethyl)-5-(4-octylphenyl)pentyl] dihydrogen phosphate","2-Carboxy-5,7-dimethyl-4-octanolide","N-Stearoyl Valine","Mono-(2-ethyl-5-hydroxyhexyl) phthalate","Cholylcysteine","Caffeic acid 4-O-sulfate","Lactic acid","N-Oleoyl Aspartic acid","bis(Benzyloxy)methane","genistin","5b-Cyprinol sulfate","Phenol sulfate","Hydroxyprolyl-Alanine","16-HDoHE","PGP(20:3(5Z,8Z,11Z)/5-iso PGF2VI)","Gln-Glu","Gentianose","Ala-Val","Janthitrem G","Naringenin-7-O-glucoside","2-Chloro-L-alanine","xi-7-Hydroxyhexadecanedioic acid","Trifluoroacetic acid","L-Lysopine","LysoPE(18:3(9Z,12Z,15Z)/0:0)","Tridecanedioic acid","N-Formylmethionine","Asn-Met","Biriperone","Phenylalanylleucine","Pyrraline","2'-Deoxyinosine","Gly-Leu","Leu-Leu-Leu","Trophicardyl","4-Oxoproline","Sativol","4-[(S)-Amino(carboxy)methyl]-3-methylbenzoic acid","1-Dodecanesulfonic acid, 1-hydroxy-3-oxo-","N2,N5-Diacetylornithine","N-Stearoyl Isoleucine","Cholylarginine","Aquex","3-HYDROXYISOBUTYRIC ACID","Austalide K","N-Arachidonoyl Proline","Docosapentaenoic acid","1-Heptadecanoylglycerophosphoethanolamine","Taraxacine","Glycolic acid","5-((1-Ethyl-4-piperidinyl)oxy)-9H-pyrrolo(2,3-b:5,4-c')dipyridine-6-carbonitrile","LysoPE(22:5(4Z,7Z,10Z,13Z,16Z)/0:0)","Carbocyclic thromboxane A2","Phaseolus epsilon","PI(16:1(9Z)/6 keto-PGF1alpha)","Olopatadine","l-Lys-l-glu","PC(6:2(3E,5E)/14:2(11E,13E))","Cinncassiol C3","Val-Val-Val","Cyheptamide","GUANOSINE","N-Myristoyl Asparagine","Valylmethionine","4-(2-((4-(2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl)oxy)ethyl)morpholine","N-Linoleoyl Valine","Leucylproline","Anhydroglycinol","2(R)-hydroxyicosanoic acid","5alpha-cholesta-8,24-dien-3-one","L-Cysteinesulfinic acid","Eicosapentaenoic acid","Chenodeoxycholyl-L-dopa","Crotonic acid","PI(18:1(9Z)/0:0)","8-hydroxy-deoxyguanosine","Linsitinib","Ala-Ile","Creatine","Leucyl-Gamma-glutamate","5-HYDROXY-TRYPTOPHAN","Carbazolepropanoic acid","PI(PGJ2/18:2(9Z,12Z))","N-Oleoyl Leucine","L-Ascorbic acid 2-sulfate","(2S)-3-Hydroxy-1-[(2S)-pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid","(+)-dethiobiotin","8-Cyclopentyl-1,3-dimethylxanthine","N-Linoleoyl Lysine","10-(2,3-Dihydroxypropoxy)-10-oxodecanoic acid","2-(3,4,5-Trimethoxybenzoyl)-4,4-diethyl-3,5-isoxazolidinedione","LysoPS(18:0/0:0)","3-Oxooctadecanoic acid","Succinic Acid","alpha-Hydroxyisobutyric acid","L-Malic acid","Doramapimod","Cyanuric acid","PI(18:3(6Z,9Z,12Z)/PGE2)","Oxalic acid","Calactin","Cholyltryptophan","Oclacitinib","bendazac","N-Tert-butyl-1-(2-sulfophenyl)methanimine oxide","4-Dodecylbenzenesulfonic acid","hydroxyoctadecadienoic acid","Islatravir","3-Hydroxyglabrol","LysoPG(18:2(9Z,12Z)/0:0)","D-Allose","7-Amino-4-(trifluoromethyl)coumarin","Cholylmethionine","TREHALOSE","Leucyl-Lysine","Nolomirole","Threonic acid","GALACTITOL","p-Cresylsulfate","Ciproxifan","Verbascose","N-Eicosapentaenoyl Leucine","Aceglutamide","Cholylalanine","Protectin D1","(1S,3R)-3-(2,2-Dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid","Sulfolithocholylglycine","Serylleucine","MOPS","Corchorifatty acid F","AMPA","9-Hydroxy-10-O-D-glucuronoside-12Z-octadecenoate","Coumestan","5-Oxozaleplon","Diprotin A","Myristoylglycine","N-Stearoyl Serine","Arachidonic acid","(8R,9S,13S,14S)-3-Hydroxy-13-methyl-4,6,7,8,9,11,12,14,15,16-decahydro-3H-cyclopenta[a]phenanthren-17-one","Pitheduloside A","Fenhexamid","CITRATE","N-Oleoyl GABA","Picrinine","1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine","PA(10:0/8:0)","Phosphoric acid","Menadione bisulfite","N-Linoleoyl Glutamic acid","N-Docosahexaenoyl Alanine","Cholestane-3,7,12,25-tetrol-3-glucuronide","N-[2-(3,4-Dimethoxyphenyl)ethyl]-3,4-dimethoxycinnamic acid amide","N-Palmitoyl Serine","6-Aminopenicillanic acid","PI(18:1(9Z)/16:1(9Z))","Ribonolactone","N-Myristoyl Serine","alpha-CEHC","(S)-N1-((1H-Benzo[d]imidazol-2-yl)methyl)-N1-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine","O-Methylpsychotrine","Dehydromonocrotaline","Glycerophospho-N-Arachidonoyl Ethanolamine","Valylhydroxyproline","(S)-3,4-Dihydroxybutyric acid","epi-dihydrophaseic acid","13-HPODE","Homovanillic acid sulfate","N-Lactoylleucine","N-oleoyl taurine","(S)-8-Prenylphaseollinisoflavan","5-HEPE","6-Hydroxydaidzein 4'-glucoside","1-Aminocyclopropane-1-carboxylate","Acetylenedicarboxylic acid","N-Acetylornithine","Palmitoyl Glycine","Pyroglutamic acid","Cholyllysine","Setoperone","N(5)-ethyl-L-glutamine","L-ASPARTATE","Tyrosyl-Isoleucine","LysoPE(20:3(11Z,14Z,17Z)/0:0)","L-(+)-Leucic Acid","Frangulanine","Dodecanedioic acid","(S)-Oleuropeic acid","Isomaltose","Ethyl formate","Methyl sulfate","Lansioside B","14,19-Didehydrocondyfolan","Imepitoin","(3a,5b,7a,12a)-24-[(carboxymethyl)amino]-1,12-dihydroxy-24-oxocholan-3-yl-b-D-Glucopyranosiduronic acid","SUBERIC ACID","3-Hydroxyhexadecanoic acid","L-Glutamine","Tyrosyl-Threonine","N-Salicyloylaspartic acid","Khellin","3-Hydroxy-4-isopentenyl-5-methoxybibenzyl-2-carboxylic acid","(S)-Laudanosine","Cholesterol phosphate","Filipin II","Gln-Trp","Dibutyl phthalate","m-hydroxy-Hydrocinnamic acid","LysoPC(6:0/0:0)","Methionyl-Leucine","BIDISOMIDE","16alpha-Hydroxytestosterone","Glu-Thr","LysoPE(P-18:1(9Z)/0:0)","N-Stearoyl phenylalanine","3-Hydroxysebacic acid","Maculine","2-[(6-Aminopurin-9-yl)methoxy]ethyl dihydrogen phosphate","Orotic acid","6-Oxopiperidine-2-carboxylic acid","2-hydroxyacrylic Acid","LysoPE(18:2(9Z,12Z)/0:0)","Bicyclo Prostaglandin E2","THIAMIPRINE","Leucylalanine","N-Docosahexaenoyl Lysine","Propiverine N-oxide","Isoforskolin","Cortistatin A","Apigetrin","o-Tyrosine","GLUCONIC ACID","Atevirdine","Undecanedioic acid","N-oleoyl L-serine","Canrenoic acid","Diamidino-2-phenylindole","1,4,8,11-Tetraoxacyclotetradecane","1,3-Dipyrenylpropane","Pyruvaldehyde","Cholylphenylalanine","LysoPC(22:5(4Z,7Z,10Z,13Z,16Z)/0:0)","(R)-3-Hydroxy myristic acid","PGP(18:1(11Z)/20:4(5Z,8Z,11Z,14Z)-OH(16R))","Gln-Phe","N-Palmitoyl Isoleucine","DL-Carbidopa","Cerebronic acid","pantoic acid","NOTA","5-HETE","Nutriacholic acid","Citramalic acid","Gly-Tyr","Norquetiapine","Azelaic acid","5-(2,3-Dihydroxy-3-methylbutyl)-4-(3,4-epoxy-4-methylpentanoyl)-3,4-dihydroxy-2-isopentanoyl-2-cyclopenten-1-one","Vatinoxan","Glycyl-Methionine","Binaltorphimine","Dibenzo[a,c]cyclooctene, 5,6,7,8-tetrahydro-","L-2-Hydroxyglutaric acid","(+/-)9-HpODE","Tripdiolide","Asn-Leu","CYCLIC GMP","gamma-Glutamylserine","(6beta,7alpha,12beta,13beta)-7-Hydroxy-11,16-dioxo-8,14-apianadien-22,6-olide","Ser-Trp","2-Hydroxymyristic acid","Asp-Val","Met-Ile","fulvic acid","-Muricholic acid","PI(20:2(11Z,14Z)/PGE2)","7-Methyl-cholic acid","(3R)-beta-leucine","Pyro-L-glutaminyl-L-glutamine","Uridine 5'-diphospho-N-acetylglucosamine","2,5-Furandicarboxylic acid","Deoxycholic acid","4-HDoHE","gamma-Glutamylglycine","N-Linoleoyl Serine","Mesoporphyrin IX dichloride","2-Hydroxyphenylacetic acid","Licoagroside B","LTC4","Juniperic acid","PROPOFOL GLUCURONIDE","Asiaticoside","CMPF","Glutamyltryptophan"],"additional_accession":[]},"is_claimable":false,"name":"Dietary Cetobacterium somerae LY-01 improves lipid metabolism and intestinal health in largemouth bass (Micropterus salmoides) fed a high-fat diet","description":"Non-targeted metabolomics sequencing was performed on the control group diet (C), the high-fat group diet (H), and the high-fat + Cetobacterium somerae LY-01 (HCS9) diet to investigate their effects on intestinal health.","dates":{"publication":"2026-09-03","submission":"2026-09-03"},"accession":"MTBLS15536","cross_references":{"HMDB":["HMDB0000696","HMDB0000158","HMDB0000210","HMDB0000517","HMDB0028823","HMDB0028822","HMDB0037942","HMDB0002005","HMDB0000194","HMDB0000036","HMDB0000269","HMDB0000651","HMDB0000946","HMDB0000167","HMDB0028844","HMDB0013122","HMDB0000706","HMDB0029087","HMDB0000062","HMDB0028801","HMDB0010384","HMDB0029093","HMDB0240783","HMDB0000148","HMDB0029096","HMDB0000756","HMDB0034276","HMDB0001325","HMDB0000791","HMDB0028854","HMDB0000954","HMDB0028912","HMDB0244507","HMDB0000258","HMDB0011180","HMDB0000848","HMDB0061859","HMDB0254979","HMDB0259191","HMDB0037061","HMDB0000301","HMDB0001161","HMDB0028756","HMDB0011149","HMDB0000043","HMDB0002250","HMDB0029930","HMDB0000925","HMDB0028825","HMDB0242219","HMDB0002117","HMDB0000875","HMDB0028954","HMDB0000824","HMDB0000619","HMDB0000870","HMDB0011718","HMDB0004949","HMDB0000883","HMDB0256501","HMDB0000562","HMDB0000251","HMDB0000182","HMDB0029042","HMDB0000252","HMDB0011749","HMDB0001488","HMDB0028918","HMDB0028810","HMDB0000722","HMDB0012273","HMDB0028909","HMDB0001065","HMDB0251215","HMDB0028898","HMDB0007991","HMDB0000168","HMDB0000352","HMDB0034587","HMDB0000244","HMDB0029090","HMDB0000132","HMDB0062590","HMDB0028831","HMDB0000187","HMDB0002100","HMDB0000097","HMDB0240780","HMDB0062195","HMDB0007965","HMDB0000721","HMDB0041878","HMDB0028803","HMDB0003217","HMDB0011177","HMDB0029091","HMDB0240643","HMDB0000162","HMDB0255912","HMDB0011567","HMDB0302261","HMDB0000157","HMDB0029135","HMDB0001432","HMDB0000138","HMDB0000214","HMDB0002335","HMDB0029737","HMDB0031345","HMDB0029109","HMDB0000917","HMDB0035214","HMDB0008043","HMDB0251169","HMDB0000874","HMDB0005065","HMDB0259044","HMDB0251526","HMDB0000673","HMDB0250981","HMDB0029052","HMDB0030776","HMDB0255056","HMDB0028993","HMDB0028893","HMDB0032616","HMDB0000949","HMDB0031199","HMDB0008100","HMDB0254199","HMDB0000101","HMDB0001008","HMDB0249482","HMDB0000518","HMDB0013302","HMDB0004610","HMDB0243946","HMDB0034146","HMDB0000212","HMDB0249033","HMDB0029094","HMDB0034301","HMDB0011506","HMDB0002134","HMDB0033529","HMDB0012275","HMDB0029118","HMDB0034297","HMDB0245404","HMDB0028848","HMDB0000510","HMDB0000271","HMDB0030670","HMDB0000050","HMDB0034198","HMDB0012209","HMDB0246597","HMDB0028913","HMDB0028929","HMDB0028906","HMDB0243496","HMDB0000889","HMDB0011130","HMDB0028694","HMDB0011179","HMDB0303570","HMDB0001336","HMDB0029068","HMDB0028765","HMDB0004207","HMDB0028818","HMDB0002183","HMDB0034381","HMDB0010382","HMDB0253028","HMDB0000766","HMDB0008039","HMDB0000583","HMDB0002322","HMDB0029044","HMDB0000235","HMDB0028920","HMDB0028795","HMDB0010169","HMDB0256449","HMDB0039517","HMDB0000201","HMDB0000687","HMDB0029030","HMDB0029008","HMDB0028910","HMDB0004363","HMDB0006455","HMDB0255027","HMDB0254014","HMDB0029001","HMDB0031599","HMDB0005049","HMDB0002068","HMDB0303539","HMDB0028738","HMDB0259742","HMDB0028739","HMDB0011131","HMDB0001320","HMDB0032055","HMDB0247327","HMDB0003331","HMDB0011637","HMDB0243960","HMDB0000896","HMDB0029029","HMDB0000300","HMDB0013078","HMDB0028998","HMDB0000573","HMDB0005862","HMDB0028695","HMDB0010224","HMDB0000015","HMDB0028743","HMDB0031810","HMDB0240219","HMDB0003231","HMDB0304810","HMDB0029010","HMDB0029000","HMDB0244898","HMDB0014513","HMDB0031641","HMDB0002088","HMDB0304413","HMDB0000640","HMDB0028896","HMDB0258243","HMDB0258202","HMDB0029126","HMDB0029028","HMDB0254854","HMDB0031581","HMDB0029081","HMDB0000522","HMDB0244776","HMDB0029104","HMDB0000163","HMDB0029131","HMDB0029069","HMDB0029045","HMDB0000192","HMDB0029112","HMDB0000089","HMDB0004824","HMDB0033936","HMDB0008097","HMDB0029528","HMDB0253384","HMDB0039323","HMDB0031195","HMDB0000220","HMDB0028693","HMDB0028994","HMDB0029559","HMDB0256612","HMDB0029308","HMDB0028917","HMDB0029140","HMDB0257877","HMDB0028747","HMDB0028800","HMDB0256518","HMDB0248208","HMDB0002815","HMDB0029046","HMDB0034649","HMDB0041263","HMDB0000086","HMDB0252495","HMDB0259337","HMDB0028995","HMDB0031659","HMDB0251566","HMDB0039489","HMDB0030689","HMDB0246143","HMDB0029005","HMDB0028846","HMDB0028764","HMDB0034355","HMDB0015361","HMDB0000241","HMDB0000305","HMDB0000307","HMDB0004669","HMDB0302622","HMDB0248759","HMDB0003312","HMDB0000564","HMDB0244876","HMDB0246947","HMDB0304396","HMDB0256086","HMDB0007978","HMDB0244975","HMDB0007945","HMDB0029016","HMDB0000827","HMDB0028892","HMDB0028901","HMDB0028944","HMDB0250258","HMDB0031103","HMDB0000067","HMDB0241100","HMDB0000032","HMDB0028988","HMDB0000070","HMDB0029015","HMDB0031331","HMDB0015104","HMDB0028905","HMDB0012252","HMDB0112078","HMDB0008330","HMDB0256157","HMDB0060997","HMDB0039937","HMDB0000852","HMDB0014257","HMDB0029074","HMDB0242431","HMDB0029006","HMDB0259122","HMDB0029076","HMDB0302136","HMDB0007938","HMDB0031463","HMDB0032672","HMDB0252743","HMDB0041996","HMDB0245812","HMDB0060717","HMDB0039150","HMDB0000245","HMDB0112092","HMDB0010404","HMDB0011477","HMDB0029368","HMDB0000898","HM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