{"database":"MetaboLights","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Tabular":["ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/m_MTBLS15562_LC-MS_positive_reverse-phase_v2_maf.tsv","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/m_MTBLS15562_LC-MS_negative_reverse-phase_v2_maf.tsv"],"Txt":["ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/a_MTBLS15562_LC-MS_negative_reverse-phase.txt","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/a_MTBLS15562_LC-MS_positive_reverse-phase.txt","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/i_Investigation.txt","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/s_MTBLS15562.txt"],"Raw":["ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/Con5-pos.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/Con6-neg.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/Con6-pos.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/Con5-neg.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/Con3-pos.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/Con4-pos.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/CrH5-pos.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/Con4-neg.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/Con2-pos.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/CrH6-pos.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/Con1-pos.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/CrH4-neg.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/CrH2-pos.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/Con1-neg.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/QC4-neg.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/QC2-pos.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/CrH3-neg.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/Con2-neg.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/CrH6-neg.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/CrH3-pos.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/Con3-neg.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/CrH5-neg.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/CrH4-pos.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/CrH1-neg.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/CrH2-neg.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/QC1-neg.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/QC1-pos.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/QC4-pos.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/CrH1-pos.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/QC2-neg.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/QC3-pos.raw","ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562/FILES/RAW_FILES/QC3-neg.raw"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"ftp_download_link":["ftp://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS15562"],"metabolite_identification_protocol":["Metabolites were annotated by matching accurate mass, retention time, and MS/MS fragmentation information against mzCloud, mzVault, and MassList databases. Positive and negative ion mode datasets were processed separately."],"repository":["MetaboLights"],"study_status":["Public"],"ptm_modification":[""],"instrument_platform":["Liquid Chromatography MS - negative - reverse-phase","Liquid Chromatography MS - positive - reverse-phase"],"chromatography_protocol":["Chromatographic separation was performed using a Vanquish UHPLC system equipped with a Hypersil GOLD C18 column (100 x 2.1 mm, 1.9 um; Thermo Fisher Scientific). The column temperature was maintained at 40 degrees C and the flow rate was 0.2 mL/min. For positive ion mode, mobile phase A was 0.1% formic acid in water and mobile phase B was methanol. For negative ion mode, mobile phase A was 5 mmol/L ammonium acetate in water adjusted to pH 9.0 and mobile phase B was methanol."],"publication":["Colostrum metabolomic profiling of periparturient dairy cows supplemented with high-dose chromium propionate before calving."],"submitter_name":["yuzhen Sui"],"submitter_affiliation":["North West Agriculture and Forestry University"],"organism_part":["colostrum"],"technology_type":["mass spectrometry assay"],"disease":[""],"extraction_protocol":["Approximately 100 mg of thawed and well-mixed colostrum sample was extracted with 500 uL of pre-chilled 80% methanol. Samples were homogenized on ice, vortexed thoroughly, incubated on ice for 5 min, and centrifuged at 15,000 x g for 20 min at 4 degrees C. The supernatant was diluted with LC-MS-grade water to a final methanol concentration of 53%, centrifuged again under the same conditions, and used for LC-MS/MS analysis. Quality control samples were prepared by pooling equal aliquots of all sample extracts."],"organism":["Bos taurus"],"full_dataset_link":["https://www.ebi.ac.uk/metabolights/MTBLS15562"],"author":["yuzhen Sui. North West Agriculture and Forestry University. sui1632020@163.com."],"data_transformation_protocol":["Raw LC-MS/MS data were processed using Compound Discoverer software version 3.3. Data processing included retention time correction, peak detection, peak alignment, peak area integration, and relative quantification. Peak intensities were normalized using the total peak area method. Metabolic features with a coefficient of variation greater than 30% in quality control samples were excluded from downstream analysis."],"study_factor":["Treatment"],"submitter_email":["sui1632020@163.com"],"sample_collection_protocol":["Colostrum samples were collected from Holstein dairy cows at the first milking after calving. Teats were cleaned and disinfected before milking, and the whole first milking was mixed thoroughly before representative colostrum samples were transferred into sterile tubes. Samples were immediately frozen in liquid nitrogen and stored at -80 degrees C until untargeted LC-MS/MS metabolomic analysis. The analyzed samples were obtained from cows in the control and high-dose chromium propionate supplementation groups."],"omics_type":["Metabolomics"],"study_design":["Orbitrap Exploris 120 mass spectrometer, Thermo Fisher Scientific","Metabolomics","LC-MS/MS","untargeted metabolomics","colostrum","untargeted analysis","Vanquish UHPLC system, Thermo Fisher Scientific","Bos taurus","pooled sample"],"curator_keywords":["Orbitrap Exploris 120 mass spectrometer, Thermo Fisher Scientific","Metabolomics","LC-MS/MS","untargeted metabolomics","colostrum","untargeted analysis","Vanquish UHPLC system, Thermo Fisher Scientific","Bos taurus","pooled sample"],"mass_spectrometry_protocol":["Mass spectrometric detection was performed using an Orbitrap Exploris 120 high-resolution mass spectrometer equipped with an electrospray ionization source. Samples were analyzed separately in positive and negative ion modes. The spray voltage was set to 3.5 kV, and full-scan MS data were acquired over an m/z range of 100-1,500. MS/MS spectra were acquired in data-dependent acquisition mode for metabolite structural annotation."],"metabolite_name":["Cer 20:0;2O/15:0;O(FA 16:0)","LPS 16:0","Corticosterone","Leu-Pro","N-Acetyl-伪-D-glucosamine 1-phosphate","Riboflavin","DL-Panthenol","LPA 14:0","FAHFA 18:0/18:2","13(S)-HOTrE","Lysope 14:0","Deoxyinosine","Cytidine-5'-monophosphate","D-(-)-Mannitol","Cer 25:1;2O/15:0;O(FA 18:1)","2-Butoxyacetic acid","SM 8:1;2O/27:0","Deoxycholic Acid","Isobutyryl carnitine","SM 9:1;2O/30:1","PG 18:2_18:2","Dl-Glyceraldehyde3-phosphate","FAHFA 20:1/20:3","LPE O-14:1","(卤)11-HETE","Prostaglandin H1","D-(-)-Quinic acid","PS 18:0_18:1;3O","Prostaglandin H2","2,3-Dinor-8-epi-prostaglandin F2伪","2,3-Dinor-TXB2","N2-Methylguanosine","FAHFA 18:2/20:4","D-Glucuronic acid","PG O-22:0_18:1","2-Ketoadipic acid","1a,1b-Dihomo prostaglandin F2伪","13,14-dihydro-15-keto Prostaglandin D1","Cer 23:0;2O/13:0;O(FA 14:0)","SM 8:1;2O/16:0","PI 16:0_18:3","FAHFA 19:1/18:0","PE O-16:1_18:1","PI 16:0_18:2","Ursolic acid","LNAPE 18:1/N-6:0","PE 18:1_20:1","PG 16:0_18:2","PG 16:0_18:1","Dl-Indole-3-lactic acid","LPS 17:1","Prostaglandin E2","2-deoxyglucose-6-phosphate","Prostaglandin E1","Ethyl-尾-D-glucuronide","Roquefortine C","6尾-Prostaglandin I1","LPI 22:4","LPI 22:5","Cer 25:0;2O/13:0;O(FA 14:0)","LNAPS 15:0/N-9:0","Paracetamol","2-Methoxyestrone","PC 14:0_14:0","PC 10:0_14:0","CerP 15:0;2O/10:0","17伪-Hydroxyprogesterone","LPE O-13:1","FAHFA 20:4/22:5","MGDG O-12:0_16:0","Methyltestosterone","FAHFA 16:0/22:5","Cer 16:1;2O/16:2;O(FA 18:2)","all-cis-4,7,10,13,16-Docosapentaenoic acid","(+/-)12(13)-DiHOME","LNAPE 18:1/N-24:0","Isoferulic acid","PE O-15:1_14:0","FAHFA 18:1/14:1","PE O-17:0_22:4","trans-10-Heptadecenoic acid","Deoxyribose 5-Phosphate","N-Acetylneuraminic acid","Pantothenic acid","PMeOH 16:0_18:3","Glycerol 3-phosphate","PMeOH 16:0_18:2","Tyrosylalanine","PE 16:0_18:1","Guanosine","N-Acetyl-L-methionine","3-Hydroxydecanoic acid","Adenosine diphosphate (ADP)","PE 16:0_18:2","HexCer 18:1;3O/22:0;(2OH)","LPA 16:0","D-Glucosamine 6-phosphate","FAHFA 6:0/15:0","N-Acetyl-DL-norvaline","PE O-17:1_20:4","Spiculisporic Acid","Lysope 16:0","PE O-19:2_20:4","LNAPE 10:0/N-16:0","2-Hydroxy-2-methylbutanedioic acid","LPE 22:4","LPE 22:5","Ethyl chrysanthemumate","LPE 22:6","Hexadecanedioic acid","11(Z),14(Z)-Eicosadienoic Acid","Prostaglandin D1","Prostaglandin D3","1-(4-methylphenyl)-3-(2-pyridylthio)pyrrolidine-2,5-dione","PC 16:0_18:1;3O","LPA 16:3","FAHFA 18:2/22:4","PMeOH 18:2_18:2","FAHFA 18:2/22:5","8Z,11Z,14Z-Eicosatrienoic acid","PE O-16:1_16:1","trans-Petroselinic Acid","Uridine","UMP","D-Gluconic acid","SM 8:1;2O/18:1","N-Acetyl-DL-tryptophan","LPC 20:5","3-Hydroxybenzoic acid","LPC 20:3","Decanoic acid","FAHFA 4:0/18:1","LPC 20:4","FAHFA 18:3/18:3","trans-2-Butene-1,4-dicarboxylic Acid","FAHFA 4:0/18:2","PG 8:0_10:0","1-[(1R,2S,3R,5R)-5-Cyclohexyl-2,3-dihydroxycyclopentyl]-3-ethylurea","Prostaglandin F3伪","LPI 20:1","Dulcitol","LPI 20:2","LPI 20:3","LPI 20:4","LPC 20:1","Nor-9-carboxy-未9-THC","LPI 20:5","Prostaglandin A1","LPC 20:2","FAHFA 6:0/16:0","PG 10:0_14:0","PA 18:3_18:3","PE O-15:0_18:2","FAHFA 20:4/20:4","Testosterone sulfate","6-Keto-prostaglandin f1alpha","FAHFA 20:4/20:3","LNAPE 18:1/N-15:1","DL-3,4-Dihydroxyphenyl glycol","D-Ribose-1-phosphate","Cer 17:1;2O/12:1;O(FA 17:0)","PE 18:1_22:4","PE 18:1_22:5","PC 15:0_18:1","Hex2Cer 40:1;2O","Glycoursodeoxycholic acid","Cytidine 5'-Monophosphate-N-Acetylneuraminic Acid","FAHFA 16:0/20:2","MAM2201 N-pentanoic acid metabolite","HexCer 18:1;2O/18:0","LNAPE 18:2/N-18:0","LNAPE 18:2/N-18:2","2-Hydroxycinnamic acid","L-(+)-Tartaric acid","Linoleic acid","3-Hydroxy-3-methylglutaric acid","23-Norcholic acid","LPE 12:0","FAHFA 16:1/18:3","(卤)18-HEPE","Fumaric acid","Cer 25:1;2O/17:0;O(FA 18:0)","PE 18:0_20:4","Cyclohexaneacetic acid","PS 20:0_18:2","PS 20:0_18:1","2-Isopropylmalate","Phenylpyruvic acid","Cer 18:1;2O/18:0","2-Deoxyuridine","Phe-Pro","4-Hydroxyretinoic Acid","FAHFA 6:0/17:1","FAHFA 4:0/17:1","HexCer 16:1;2O/22:0","2-Methylbutyl beta-D-glucopyranoside","D-伪-Hydroxyglutaric acid","Methylsuccinic acid","Traumatic acid","Tetradecanedioic acid","PG O-25:0_18:1","Propionyl-L-carnitine","Docosahexaenoic acid","FAHFA 17:0/18:0","FAHFA 17:0/18:2","LPE 20:1","伪-D-Glucose-1,6-bisphosphate","LPE 20:2","LPE O-18:0","LPE O-18:1","LPE O-18:2","PC 18:1_18:2;O","LPC 18:2","LPC 18:3","LPE 20:5","N-Acetyl-L-tyrosine","D-Fructose 1,6-bisphosphate","LNAPE 18:2/N-4:0","MGDG O-20:0_16:0","LPI 16:0","FAHFA 2:0/20:0","LPC 18:0","Oleoyl-L-伪-lysophosphatidic acid","4-(octyloxy)benzoic acid","LPA 18:0","PE 18:1_20:5;3O","LPA 18:2","LNAPE 18:1/N-2:0","12,13-EODE","6-Sialyllactose","LNAPE 16:1/N-22:4","(卤)9-HpODE","DGGA 16:0_18:3","FAHFA 4:0/16:1","DGGA 16:0_18:2","FAHFA 4:0/16:0","FAHFA 6:0/18:1","cis-7-Hexadecenoic Acid","(卤)12(13)-DiHOME","PE 16:0_17:1","HexCer 16:1;2O/23:0","MGDG O-16:4_12:0","HexCer 18:1;2O/20:0","cis-2-Decenoic acid","LPE O-17:1","PE 18:2_20:4","FAHFA 18:1/22:4","D-Fructose 1-phosphate","N2-(2,3-dihydrobenzo[b]furan-5-ylmethyl)-2-thiophenesulfonamide","LPI 15:0","11(E)-Eicosenoic Acid","Xanthosine","PA 16:0_18:3","PA 16:0_18:2","2,2-Dimethylsuccinic acid","6-Phosphogluconic acid","Cer 25:0;2O/13:0;O(FA 16:1)","Citric acid","LPA 17:1","LPE 10:0","PE O-19:1_18:2","PE 18:1_18:2;2O","LPG 20:3","LPG 20:4","13Z,16Z-Docosadienoic Acid","SM 8:1;2O/19:0","LPG 20:0","tetranor-12(R)-HETE","MGDG O-24:4_16:0","HexCer 18:0;2O/20:2","Prostaglandin K1","PE 17:0_18:1","ST 29:2;O;Hex;FA 18:1","LNAPE 20:4/N-15:1","Cer 16:0;2O/18:0","Glycocholic acid","P-Coumaroyl Agmatine","FAHFA 20:3/18:2","LPC 8:0","LPE O-16:1","PE O-15:1_20:3","PE O-18:2_20:3","Cer 27:0;2O/12:0;O(FA 18:2)","(+/-)11-HETE","Levodopa","Stearic acid","Flavin adenine dinucleotide","LNAPE 18:2/N-2:0","Orotidine","Jasmonic acid","L-Ascorbate","LPG 10:0","Tretinoin","N'1-phenylpropanohydrazide","LPI 14:0","Cinnamoylglycine","LNAPE 18:1/N-18:1","Adrenosterone","D-(+)-Galactose","1-Palmitoyl-Sn-Glycero-3-Phosphocholine","Hydroquinone","2-Furoylglycine","2,5-Dimethylphenol","HexCer 27:1;2O/11:0","LNAPE 18:1/N-4:0","PE 18:1_18:1;3O","Monobutyl phthalate","Taurochenodeoxycholic acid","FAHFA 22:4/18:0","PE O-18:0_20:4","Vanillyl alcohol","Cer 18:0;2O/16:0","PG 18:0_18:2","(卤)8(9)-DiHET","Hydrocortisone","LPE O-15:1","10-Hydroxydecanoic acid","PS 18:1_22:4","L-Adrenaline","4-Methylvaleric Acid","Cer 18:2;2O/23:0","FAHFA 17:1/20:4","PS 18:1_18:2;O","Deoxycorticosterone 21-glucoside","cis-Aconitic acid","MGDG O-20:0_17:1","LPS 22:4","LPS 22:5","7-Ketolithocholic acid","Prostaglandin J2","LPS 22:6","LNAPE 18:1/N-19:1","FAHFA 18:0/2:0","D-(+)-Malic acid","Biocytin","PE O-21:2_18:2","4-Hydroxy-2-Oxoglutaric Acid","PS 18:0_17:1","D-Ribose","4-Hydroxyisoleucine","Tridecylic acid","LPG 22:5","Ethyl myristate","LPG 22:4","FAHFA 14:1/16:3","(卤)11(12)-DiHET","Taurine","Naringenin","Allantoin","12-epi Leukotriene B4","7-Hydroxy-3,4-dihydrocarbostyril","Arachidic acid","DL-4-Hydroxyphenyllactic acid","LPA 6:0","FAHFA 16:0/18:0","FAHFA 16:0/18:2","2-Hydroxyhippuric acid","N-Acetylsphingosine","HexCer 18:1;3O/24:0;(2OH)","8(S),15(S)-DiHETE","FAHFA 18:2/17:0","Tetrahydroaldosterone","o-Toluic Acid","FAHFA 18:2/17:2","LPG 12:0","LPC O-14:1","LPC 14:0","15(R),19(R)-Hydroxy prostaglandin F1伪","DL-Malic acid","LPC 14:1","ST 24:2;O4","8,12-iso-iPF2伪-VI","MGDG O-13:1_20:4","1,5,8-Trihydroxy-9-oxo-9H-xanthen-3-yl beta-D-glucopyranoside","Catechol","Porphobilinogen","FAHFA 17:1/18:3","PE O-18:1_18:1","FAHFA 17:1/18:2","2-Oxoglutaric acid","Docosatrienoic Acid","PE-Cer 12:1;2O/22:0","PE O-21:1_18:1","PI 18:0_18:1","Lysops 22:5","FAHFA 19:1/20:2","HexCer 18:1;2O/24:0","HexCer 18:1;2O/24:1","FAHFA 19:1/20:3","Undecanoic acid","Lauric acid","trans-Aconitic acid","PS 18:1_20:3","MGDG O-28:6_18:1","PS 18:1_20:1","PE O-17:0_18:3","Docosapentaenoic acid","Octanedioic acid","LNAPE 18:2/N-9:0","Gentisic acid","6-Deoxy-D-glucose","4-Butylresorcinol","3-Methyladipic acid","Lithocholic Acid","Cer 18:1;2O/24:0","Pentadecanoic acid","Lysops 22:6","LPS 20:3","LPI 6:0","LPC 15:0","LPS 20:4","13,14-Dihydro-15-keto Prostaglandin A2","FAHFA 20:5/16:2","FAHFA 18:0/20:2","Thymidine 5'-monophosphate","UDP-galactose","Phenylacetylglycine","Sorbitan monopalmitate","DGDG 18:3_18:3","(卤)9(10)-DiHOME","LPS 20:1","Pyrogallol","2-(Formylamino)Benzoic Acid","2-Methoxyestradiol","Dibutyl sebacate","SM 8:1;2O/30:1","LysoPE 18:0","(+/-)7(8)-DiHDPA","Eicosapentaenoic acid","4-Aminobutyric acid","Lysopc 17:0","acetyl phospahte","D-Xylonic Acid","PE O-19:1_20:4","PE 18:1_20:5;O","LPA 8:0","HexCer 18:1;2O/23:0","LNAPE 18:2/N-6:0","PE O-16:1_20:4","Caprylic acid","PI 18:0_18:1;3O","3,4-Dihydroxyphenylpropionic acid","LPG 14:0","D-Glucose 6-phosphate","(S)-Leucic acid","FAHFA 20:5/17:2","LPC 16:0","LPC 16:1","4-[3,5-di(tert-butyl)-1H-pyrazol-1-yl]benzoic acid","N-[3-(aminosulfonyl)phenyl]-2,3-dihydro-1,4-benzodioxine-2-carboxamide","L-aspartic Acid","LPI 18:3","LPI 18:2","LPI 18:1","Lauric acid ethyl ester","PC 8:0_10:0","N-acetyl-D-glucosamine","6,15-diketo-13,14-dihydro Prostaglandin F1伪","Myristic acid","1,3-Dimethyluric Acid","1-(4-Methoxyphenyl)-2-propanone","5-Sulfosalicylic acid","1,2-Dipalmitoylphosphatidylglycerol","2-(1-{2-[(3-furylmethyl)amino]-2-oxoethyl}cyclohexyl)acetic acid","Succinic acid","17-AAG","Prostaglandin A1 ethyl ester","LPE 19:2","L-Malate","FAHFA 20:4/18:3","Adipic acid","PE 18:1_20:4;2O","Gluconolactone","(+/-)8(9)-DiHET","HexCer 13:2;2O/40:9","Phosphatidylinositol-1,2-dipalmitoyl","Adrenic acid","Cer 24:0;2O/15:0;O(FA 18:1)","N-Acetyl-DL-phenylalanine","15-OxoEDE","Hex2Cer 36:1;2O","MGDG O-22:4_15:0","FAHFA 18:1/20:2","Hippuric acid","PE 18:1_20:6;O","HexCer 18:1;2O/22:0","FAHFA 17:0/19:2","(2S)-4-Oxo-2-phenyl-3,4-dihydro-2H-chromen-7-yl beta-D-glucopyranoside","DGDG 18:2_18:2","ST 28:1;O;Hex;FA 18:1","ST 28:1;O;Hex;FA 18:2","FAHFA 18:2/18:2","SM 8:1;2O/20:0","FAHFA 18:2/18:3","LPG 15:0","2-Hydroxybutyric acid","Cer 18:1;2O/22:0","MGDG O-24:6_16:1","Quinolinic acid","FAHFA 18:1/20:3","5-Methyluridine","DGDG 16:0_18:1","LPI 17:0","DGDG 16:0_18:2","2-[({4-[3,5-di(tert-butyl)-1H-pyrazol-1-yl]phenyl}imino)methyl]phenol","PE 16:0_22:4","N'1-[1-(2-hydroxyphenyl)ethylidene]-3-methoxybenzene-1-carbohydrazide","DGDG 16:0_18:3","LPC 17:0","FAHFA 20:5/18:3","Glutaconic acid","Cer 16:1;2O/24:1","Cer 16:1;2O/24:0","MGDG 22:1_18:2","JWH 018 N-pentanoic acid metabolite","LPI 17:1","HexCer 18:1;2O/10:0","8-iso Prostaglandin A1","8-iso Prostaglandin A2","8(S)-Hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoic acid","SM 8:1;2O/32:1","SM 8:1;2O/32:0","Citraconic acid","2-Ethylhexanoic acid","FAHFA 20:4/17:2","Inosine","Cer 18:1;2O/10:0","15(S)-HpETE","Purine","PE O-17:1_18:2","PE 18:1_18:2","Uridine monophosphate (UMP)","Corchorifatty acid F","Oxoadipic Acid","尾-D-Glucopyranuronic acid","N-Acetyl-L-phenylalanine","MGDG O-20:4_14:0","LPA 10:0","Cholic acid","Arachidonic acid","螖17-6-keto prostaglandin F1伪","2'-Deoxyinosine 5'-monophosphate","2,3-dinor Prostaglandin E1","PA 18:0_18:2","Prostaglandin F1尾","16-Hydroxyhexadecanoic acid","LPG 16:1","Cer 14:0;2O/12:0;O(FA 18:1)","LPG 16:0","LNAPE 16:0/N-14:1","Ureidosuccinic acid","Cer 23:0;2O/13:0;O(FA 16:1)","N1-(1,3,4-thiadiazol-2-yl)-2-(benzoylamino)benzamide","N-Oleoyl Glycine","3,5-Dihydroxybenzoic acid","LPC O-18:0","LPC O-18:1","FAHFA 17:0/22:4","Cer 16:0;2O/20:0","Nonanoic acid","12-Hydroxydodecanoic acid","NSI-189","Maltotriose","Valproic acid","LPC 10:0","Cer 16:1;2O/23:0","PC 16:0_20:4;O","Sebacic acid","FAHFA 16:1/17:2","(3-Methoxy-4-hydroxyphenyl)ethylene glycol sulfate","carbamazepine-d10","3-Methoxyphenylacetic acid","LPE 17:1","O-Phosphorylethanolamine","LPE 17:2","N4-Acetylcytidine","11-Deoxy prostaglandin F2尾","PA 18:2_18:3","11(Z),14(Z),17(Z)-Eicosatrienoic acid","PA 18:2_18:2","LPC 22:4","Dihydroroseoside","Ethylmalonate","3-Indoxyl sulphate","Flavin mononucleotide (FMN)","D-(-)-Fructose","PE 18:0_20:4;O","LPC 22:5","4-Methyl-2-Oxopentanoic Acid","PE 18:2_28:4","FAHFA 2:0/18:0","Cer 16:1;2O/10:0","6-Hydroxymelatonin","D-Glucarate","Thr-Leu","4-Hydroxy-3-methylbenzoic acid","Glucose 1-phosphate","LPG 6:0","(+/-)9,10-dihydroxy-12Z-octadecenoic acid","15(R)-Prostaglandin E2","Salicylic acid","SM 8:0;2O/29:0","Dodecanedioic acid","PI 18:1_18:2","LPA 20:3","Diflorasone","Cer 16:1;2O/22:0","Cer 20:0;2O/15:0;O(FA 18:1)","FAHFA 16:1/16:2","D-Sedoheptulose 7-phosphate","FAHFA 18:1/18:2","SM 8:1;2O/34:0","Quinic acid","17伪-Hydroxypregnenolone","ST 24:1;O4;T","LPE 18:0","LPE 18:1","PE O-15:1_18:1","LPE 18:2","PE O-15:1_18:2","LPE 18:3","Adenosine 5'-monophosphate","PE 18:0_20:5;O","Hex2Cer 39:1;2O","Cer 16:0;2O/10:0","LPS 18:0","L-Hydroxyproline","LPS 18:1","FAHFA 15:0/16:2","PS 18:1_18:2","PE 15:0_18:1","Thymidine","LNAPE 18:1/N-22:6","LPG 18:3","DGGA 18:2_18:3","5-Phenyl-N-(4-(trifluoromethyl)phenyl)oxazol-2-amine","DGGA 18:2_18:2","LPG 18:1","LPG 18:0","PS 18:0_22:5","LPS 18:2","N-Tigloylglycine","Nicotinamide N-oxide","LPS 18:3","(卤)11(12)-EET","Flavin adenine dinucleotide (FAD)","3-Phosphoglyceric acid","LPC O-16:1","Gluconic acid","LPC 12:0","15-Deoxy-螖12,14-prostaglandin D2","7-Methylxanthine","Cer 24:0;2O/15:0;O(FA 16:0)","SM 8:0;2O/26:0","2-Hydroxy-3-methylbutanoic acid","2-Furoic acid","Cer 16:0;2O/22:0","Homo-Gamma-Linolenic Acid (C20:3)","FAHFA 20:3/22:5","Erythronolactone","PS 16:0_18:1","PS 16:0_18:2","Phenobarbital","FAHFA 18:1/19:2","13,14-dihydro-15-keto-tetranor Prostaglandin F1尾","LNAPE 18:1/N-21:0","Protoporphyrin IX","LPE 15:0","13,14-dihydro-15-keto-tetranor Prostaglandin E2","(R)-3-Hydroxy myristic acid","1a,1b-Dihomo prostaglandin E1","Lipoic acid","Phe-Phe","20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid","MGDG O-20:0_20:3","伪-D-Mannose 1-phosphate","HexCer 18:2;2O/23:0","Elaidic acid","FAHFA 15:0/17:2","4-oxo-4,5,6,7-tetrahydrobenzo[b]furan-3-carboxylic acid","3-Oxo-7alpha,12alpha-hydroxy-5beta-cholanoic acid","HexCer 18:1;3O/23:0;(2OH)","PC O-16:0_18:1","Cynaropicrin","Azelaic acid","LPS 19:1","Cer 18:1;2O/4:0","Medroxyprogesterone","Palmitic Acid","Cer 24:0;2O/17:0;O(FA 18:0)","LPC O-17:0","Cer 16:1;2O/20:0","2-Hydroxymyristic acid","Dimetghyl 4-Hydroxyisophthalate","5-Methoxyindole-3-Carbaldehyde","FAHFA 20:2/18:0","SQDG 16:0_16:0","PC 18:2_18:3","Rutin","Guanosine monophosphate (GMP)","PA 12:0_16:0","Prostaglandin F2尾","Lysopc 16:2 (2N Isomer)","11-keto Testosterone (CRM)","N-Isobutyrylglycine","N-Isovalerylglycine","Mestranol","LPI 4:0","LPE 16:1"],"additional_accession":[]},"is_claimable":false,"name":"Colostrum metabolomic profiling of periparturient dairy cows supplemented with high-dose chromium propionate before calving","description":"This study contains untargeted LC-MS/MS metabolomic profiles of colostrum samples collected at the first milking after calving from Holstein dairy cows in the control and high-dose chromium propionate supplementation groups. Cows received either a basal total mixed ration without supplemental chromium propionate or the same ration supplemented with 20 g chromium propionate per cow per day, providing 8 mg Cr(III) per cow per day, from 21 days before expected calving until parturition. Colostrum samples were collected after teat cleaning and disinfection, mixed thoroughly from the whole first milking, and analyzed to characterize colostrum metabolic responses associated with prepartum chromium propionate supplementation during the periparturient 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