which was developed using R and based on XCMS, for feature detection, extraction, alignment, and integration.
"],"repository":["MetaboLights"],"study_status":["Public"],"ptm_modification":[""],"instrument_platform":["Liquid Chromatography MS - alternating - hilic","Liquid Chromatography MS - alternating - reverse-phase"],"chromatography_protocol":["For the polar system, chromatographic separation of the target compounds was performed on an Agilent 1290 Infinity II ultra-high performance liquid chromatography (UHPLC) system equipped with an
Atlantis Premier BEH Z-HILIC Column (1.7 µm, 2.1 mm × 150 mm). The mobile phase A consisted of ultrapure water/acetonitrile (10:90, v/v) containing 10 mmol/L ammonium acetate, and mobile phase B was ultrapure water/acetonitrile (90:10, v/v) containing 10 mmol/L ammonium acetate. The temperature of the sample tray was set at 6 °C with an injection volume of 2 μL (Note: the original volume value was garbled).
For the non-polar system, the target compounds were subjected to chromatographic separation on the same Agilent 1290 Infinity II UHPLC system with an ACQUITY UPLC BEH C18 Column (1.7 µm, 2.1 mm × 150 mm). The mobile phase A was ultrapure water with 0.1% formic acid, and mobile phase B was methanol/ultrapure water (95:5, v/v) containing 10 mmol/L ammonium formate. The temperature of the sample tray was maintained at 6 °C, with an injection volume of 1 μL (Note: the original volume value was garbled).
"],"publication":["13(S)-HODE Generated by Rhizopus microsporus var. rhizopodiformis Aggravates MASLD via the Elane-PAR2-SREBP-1c Axis."],"submitter_affiliation":["Hainan medical university"],"submitter_name":["Daya Zhang"],"organism_part":["supernate"],"technology_type":["mass spectrometry assay"],"disease":[""],"extraction_protocol":["The frozen samples were thawed on ice and vortexed for 30 s to homogenize thoroughly; 100 μL of each liquid sample was aliquoted into 1.5 mL Eppendorf (EP) tubes, followed by the addition of 400 μL of methanol as the extraction solution with subsequent vortexing for complete mixing. The mixtures were sonicated in an ice-water bath for 15 min and then incubated at -40 °C for 1 h, prior to centrifugation at 12,000 rpm and 4 °C for 15 min. The resulting supernatants were carefully transferred into injection vials for instrumental analysis. In addition, equal volumes of supernatants from all individual samples were pooled to prepare quality control (QC) samples, which were analyzed under the same instrumental conditions for quality assessment.
"],"organism":["Rhizopus microsporus var.rhizopodiformis"],"full_dataset_link":["https://www.ebi.ac.uk/metabolights/MTBLS15760"],"author":["Daya Zhang. Hainan medical university. 875025464@qq.com."],"data_transformation_protocol":["The raw data were converted to the mzXML format using ProteoWizard and processed with an in-house program.
"],"study_factor":["Group"],"submitter_email":["875025464@qq.com"],"sample_collection_protocol":["All sample pretreatment procedures were performed on ice.
"],"omics_type":["Metabolomics"],"study_design":["Thermo Scientific Vanquish UHPLC System","Fluxomics","ProteoWizard msconvert","metabolic flux analysis","untargeted analysis","Thermo Scientific Orbitrap Exploris 120","Rhizopus microsporus var.rhizopodiformis","Rhizopus microsporus","supernate","13(S)-HODE"],"curator_keywords":["Thermo Scientific Vanquish UHPLC System","Fluxomics","ProteoWizard msconvert","metabolic flux analysis","untargeted analysis","Thermo Scientific Orbitrap Exploris 120","Rhizopus microsporus var.rhizopodiformis","Rhizopus microsporus","supernate","13(S)-HODE"],"mass_spectrometry_protocol":["Mass spectrometric data acquisition for full scan MS and MS/MS spectra was conducted on an Orbitrap Exploris 120 mass spectrometer under the control of Xcalibur software (Version 4.4, Thermo Fisher Scientific). The detailed mass spectrometry parameters were set as follows: Sheath gas flow rate: 50 Arb; Aux gas flow rate: 15 Arb; Capillary temperature: 320 °C; Full MS resolution: 60000; MS/MS resolution: 15000; Collision energy: SNCE 20/30/40; Spray Voltage: 3.8 kV (positive ion mode) or -3.4 kV (negative ion mode).
"],"metabolite_name":["2,7-diamino-9H-xanthen-9-one","(2S,3R)-2-[[(2R)-2-amino-4-methylsulfanylbutanoyl]amino]-3-hydroxybutanoic acid","Muricarpone B","Panaxacol","3-Hydroxyestran-17-one","2,5-Di-tert-butylhydroquinone","Xestoaminol C","N-(2-(Dimethylamino)ethyl)-N-methyl-4-(((4-(4-morpholin-4-yl-7-(2,2,2-trifluoroethyl)-7H-pyrrolo(2,3-d)pyrimidin-2-yl)phenyl)carbamoyl)amino)benzamide","O-Methylarmepavine","5alpha-Androstan-3alpha,17beta-diol disulfate","3-[(3-carboxycyclohexyl)carbamoyl]-4-[3-[4-(4-cyclohexyloxybutoxy)phenyl]propoxy]benzoic acid","1-(2-Diethylaminoethyl)-3-phenyl-2-thiourea","1-(5-Fluoropentyl)-N-2-naphthalenyl-1H-indole-3-carboxamide","PA(18:3(6Z,9Z,12Z)/18:1(9Z))","Ectoine","1,2-Bis(3,4-dimethoxyphenyl)propane-1,3-diol","Isolupabigenin","2-Methoxyethyl 4-(3-hydroxyphenyl)-7-(2-methoxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate","Val-Met","(1-(2-Morpholin-4-ylethyl)indol-3-yl)-4-methoxynaphthalen-1-ylmethanone","Andrographiside","4-O-beta-glucosyl-indol-3-yl formamide","(2S,3R,E)-2-Aminopentadec-4-ene-1,3-diol","Anhydrocinnzeylanine","(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]pent-1-enyl]cyclopentyl]hept-5-enoic acid","N-(1-Deoxy-1-fructosyl)tyrosine","jasmonoyl-phenylalanine","Z-Tyr-Leu-NHOH","methyl (3Z)-3-[[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylate","Coumatetralyl","5-Amino-1-cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid","5-[4-(diethylamino)phenyl]-4-ethyl-4H-1,2,4-triazole-3-thiol","2,3-Dinor-TXB2","Methyl 3-(4-Methyl-2,5-dioxo-4-imidazolidinyl)propanoate","2-[1-[1-hydroxy-10,13-dimethyl-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethyl]-5-(hydroxymethyl)-4-methyl-2,3-dihydropyran-6-one","Trenbolone","Laudanosine","N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(4-hydroxypentyl)-1H-indazole-3-carboxamide","Tofacitinib","Glycylphenylalanylarginine","2-Heptenoic acid","Propacetamol","Methyl 3-(3,4-dimethoxyphenyl)propanoate","20alpha-hydroxycortisol","Licoarylcoumarin","N-(stearoyl)-sphinganine","Desmethylemetine","N2-Acetylornithine","Tyr-Ile","N-Citryl-spermidine","Glycylalanyltyrosine","4-hydroxy-6-[1-[1-(2-hydroxyethyl)-4,7-dimethyl-3,4-dihydro-1H-isochromen-3-yl]ethyl]-3-methylpyran-2-one","6-Methyl-2-oxo-1,2-dihydroquinoline-3-carbaldehyde","Deacetylchloronectrin","3-Methoxytyrosine","2,7-(Epoxypentadeca[1,11,13]trienimino)benzofuro[4,5-e]pyrido[1,2-a]benzimidazole-1,15(2H)-dione,25-(acetyloxy)-5,6,21,23-tetrahydroxy-27-methoxy-2,4,11,16,20,22,24,26-octamethyl-,(2S,16Z,18E,20S,21S,22R,23R,24R,25S,26R,27S,28E)-","5-Bromo-5'-hexyl-2,2'-bithiophene","3',5'-Cyclic GMP","2'-O-Methylguanosine","Arginine","Succinylcarnitine (C4:0,COOH)","Chlormadinone Acetate","Taurohyocholate","3-(prop-1-en-2-yl)heptanedioate","4-Pyridinecarboxaldehyde","9,10-Dihydrokadsurenone","Ala-Phe","2-[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-acetylamino]-4-methyl-pentanoic acid","Silodosin","N-(2-oxooxolan-3-yl)tetradecanamide","N3-(4-methoxyfumaroyl)-2,3-diaminopropanoate","Streptomycin","8,9-Dihydro-6H-pyrido[2,1-b]quinazolin-11(7H)-one","2-cyano-N-[4-(trifluoromethoxy)phenyl]acetamide","5-Hydroxylysine","2-[2-(3-fluorophenyl)ethynyl]-4,6-dimethylpyridin-3-amine","Estramustine","4,4,7a-trimethyl-3a,5,6,7-tetrahydro-3H-indene-1-carboxylic acid","5-Methylheptan-3-one","N,N',N''-triacetylchitotriose","3-Hydroxy-beta-ionol 3-[glucosyl-(1->6)-glucoside]","15,15-Difluoro-9alpha,11alpha-dihydroxy-16-phenoxy-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid, isopropyl ester","4-Acetamidobenzoic acid","Oleamide","Pro-Gly","methyl 4,10-diacetyloxy-5-hydroxy-1,4a-dimethyl-9-oxo-7-propan-2-yl-3,4,10,10a-tetrahydro-2H-phenanthrene-1-carboxylate","beta-Asp-Phe","methyl (1S,2R,4R,8R,9S,10R,13R,15R)-2-acetyloxy-13-(furan-3-yl)-9-(2-methoxy-2-oxoethyl)-4,8,10,12-tetramethyl-7-oxo-16-oxatetracyclo[8.6.0.03,8.011,15]hexadeca-5,11-diene-4-carboxylate","Succinyldisalicylic acid","N-acetyl-glucosaminyl-tunicaminyl-uracil","gamma-Glutamyl-alanine","Glyceraldehyde","Ergometrine","Leu-Val","4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]piperidine","[(2R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate","Epoxyfumitremorgin C","Deacetyldiltiazem","1-a-Linolenoyl-2-vaccenoyl-3-a-linolenoyl-glycerol","(9-acetyloxy-3,6,6,13-tetramethyl-12-oxo-8-tetracyclo[11.2.1.01,10.02,7]hexadec-2-enyl) benzoate","H-Arg-pro-pro-OH sulfate salt","2-[[2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]acetyl]amino]-3-(1H-indol-3-yl)propanoic acid","(2S)-2-[[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoic acid","(Z)-3-methyl-5-(1,2,5,5-tetramethyl-7-oxo-3,4,4a,6-tetrahydro-2H-naphthalen-1-yl)pent-2-enoic acid","Imazaquin","Tubocurarine [M]","Oxynarcotine","4-(4-Chloro-3-nitro-benzenesulfonyl)-morpholine","Tetraxetan","prolyl-tyrosine","4-(Cyclohexylamino)-3-nitrobenzoic acid","5-Heptenamide, 7-((1R,2R,3R,5S)-2-((1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl)-3,5-dihydroxycyclopentyl)-N-ethyl-, (5Z)-","N-Acetylnorheroin","Arginyltyrosine","Loteprednol","Mono(2-ethylhexyl) phthalate","5-(4-Piperidinyl)-3(2H)-isoxazolone","1,3,6,7-tetrahydroxy-8-prenylxanthone","1,2-dibutyrin","Ile-Gln","N-[bis(methylsulfanyl)methylidene]methanesulfonamide","Prolylalanine","Hydroxyprolyl-Leucine","4'-Chloro fentanyl","(2S)-2-[[(2R)-2-amino-4-methylsulfanylbutanoyl]amino]-3-methylbutanoic acid","Apomorphine","L-Tryptophan, N-[[(6-deoxy-alpha-L-mannopyranosyl)oxy]hydroxyphosphinyl]-L-leucyl-","21-Hydroxypregn-4-ene-3,20-dione hydrogen succinate","Benzenesulfonic acid, 3-amino-4-methyl-","[(3S,4aS,7R,8R,8aS)-3,4'-dihydroxy-4,4,7,8a-tetramethyl-6'-oxospiro[2,3,4a,5,6,7-hexahydro-1H-naphthalene-8,2'-7,8-dihydro-3H-furo[2,3-e]isoindole]-2-yl] acetate","prostaglandin D2 ethanolamide","6-Amino-1-benzyl-5-methylaminouracil","Retrorsine","1-18:2-2-18:2-phosphatidylethanolamine","5a,8-Methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol, 3b,4,5,6,7,8,9,10,10a,10b-decahydro-7-hydroxy-10b-methyl-, (3balpha,5abeta,7beta,8beta,10aalpha,10bbeta)-","2-phenyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyacetamide","prefusarin","Auranticin A","5-(4-Fluorobenzylidene)rhodanine","5-O-Desmethyl Donepezil","gamma-Glu-Ile","Torvoside D","Isovalerylcarnitine","Serine","(E)-N-[(2S,3R,4R,5R)-2-[(3R,4R,5S,6R)-3-Acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[2-[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl]-4,5-dihydroxyoxan-3-yl]-14-methylpentadec-2-enamide","Arg-Pro","2-amino-5-[2-[[(3S)-2,3-dihydroxy-2-[(1S)-1-hydroxyethyl]butanoyl]oxymethyl]anilino]-5-oxopentanoic acid","methyl (2R)-2-[[1-(cyclohexylmethyl)indole-3-carbonyl]amino]-3-methylbutanoate","Dantrolene","(1-(3-Oxo-2-aza-spiro(4.5)dec-2-ylmethyl)-cyclohexyl)-acetic acid","Gln-Asn","Phe-Thr","7,8-Dihydrovomifoliol 9-[rhamnosyl-(1->6)-glucoside]","Isocitric acid","Ile-Glu","rac Alpha-Methyl Kynurenine","Undecanedioylcarnitine","17-phenyl-18,19,20-trinor-prostaglandin E2","Anthranoyllycoctonine","Cinnzeylanine","[1-(5-Hydroxypentyl)indol-3-yl]-(4-hydroxyphenyl)methanone","N-Lauroylglycine","N-Formylmethionine Leucyl-Phenylalanine","12HpEPE","20-Trihydroxy-leukotriene-B4","Adenosine","1-Arachidonoyl-2-linoleoyl-3-a-linolenoyl-glycerol","methyl 7-acetyloxy-5-hydroxy-7-methyl-1-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-4-carboxylate","N,O-Dimethyltyrosine","cyclo(phenylalanyl-tyrosyl)","tyramine 4-O-beta-glucopyranoside","Garciduol C","Clenbuterol","Orantinib","1-hydroxy-N-(3-nitrophenyl)naphthalene-2-carboxamide","2-[3-[(E)-6-acetyloxy-2-hydroxy-6-methyl-3-oxohept-4-en-2-yl]-6-(carboxymethyl)-2-hydroxy-3a,5a,9b-trimethyl-5-oxo-2,3,4,6,9,9a-hexahydro-1H-cyclopenta[a]naphthalen-7-yl]-2-methylpropanoic acid","11S,15S-dihydroxy-14R-(S-glutathionyl)-5Z,8Z,12E-eicosatrienoic acid","Acetamide, 2,2,2-trifluoro-N-(5,6,7,9-tetrahydro-10-hydroxy-1,2,3-trimethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)-","Trosec","(1R,13R)-13,24-dimethyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-2,4(8),9,14(22),15,17(21)-hexaen-12-ol","Megaphone","2,3-Dinor-8-iso prostaglandin F2alpha","Acetyl-podocarpic dimer","Glucitol","6-[[4-(1,3-Dioxoisoindol-2-yl)phenyl]carbamoyl]-3,4-dimethylcyclohex-3-ene-1-carboxylic acid","3-Hydroxybutyric acid","6-Methyl-3-hepten-2-one, (3E)-","Uniconazole P","(17S)-7,8-Didehydro-4,5alpha-epoxy-17-methylmorphinan-3,6alpha-diol 17-oxide","Melatonin","Dodecanamide","Galdosol","(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]naphthalen-1-yl]oxyoxane-2-carboxylic acid","Isoapocodeine","Trp-Glu","2-hydroxyoct-1-enoylglycine","Afzelin","21-Deoxycortisone","Traumatic acid","Cinalukast","(14R,27R)-22,33-dimethoxy-13,28-dimethyl-2,5,7,20-tetraoxa-13,28-diazaoctacyclo[25.6.2.216,19.13,10.121,25.04,8.031,35.014,39]nonatriaconta-1(33),3(39),4(8),9,16(38),17,19(37),21,23,25(36),31,34-dodecaene","3-hydroxy-3-methyl-5-oxo-5-[[3,4,5-trihydroxy-6-[(6E)-8-methoxy-3,7-dimethyl-8-oxoocta-1,6-dien-3-yl]oxyoxan-2-yl]methoxy]pentanoic acid","N-Desmethylverapamil","tunicamycin A0","Glycidyl oleate","Tetrahydrodicranenone B","(E)-7-[3,5-dihydroxy-2-[(E)-3-hydroxy-4-thiophen-3-yloxybut-1-enyl]cyclopentyl]hept-5-enoic acid","(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-(2-methoxypropan-2-yl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate","(1R,2R,4aS,6aS,6bR,10S,11R,12aR)-1,10,11-trihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid","1-Hydroxy-3,5-dimethoxy-2,4-diprenylxanthone","[3-Azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl 2-amino-3-methylpentanoate","2-Amino-5,6,7,8-tetrahydro-cis-6,7-dimethyl-4(1H)-pteridinone","6-Gingesulfonic acid","gamma-Glutamylmethionine","Gibberellin A4","3-[4-[2-(2-methylphenyl)ethynyl]phenyl]propanoic acid","3-Amino-5-methyl-1-phenylpyrrolidin-2-one","Cycleanine","7-Hydroxysecoisolariciresinol","N-Undecanoylglycine","Cloperidone","1,26-Dicaffeoylhexacosanediol","New fuchsin free base","Valeric acid","N-(alpha-linolenoyl)tyrosine","Lysine","Cyclobenzaprine","Mono-(2-ethyl-5-oxohexyl) phthalate","(6Z,9Z,12Z,15Z)-1,1,1-Trifluoro-6,9,12,15-heneicosatetraen-2-one","5-[Bis(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester","(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[(1R)-4-(3-hydroxybutyl)-3,5,5-trimethylcyclohex-3-en-1-yl]oxyoxan-2-yl]methoxy]oxane-3,4,5-triol","S-(3-Methylbutanoyl)-dihydrolipoamide-E","PE(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/16:1(9Z))","Trehalose","[6]-Gingerdiol acetate methyl ether","(gamma-Glutamyl-gamma-glutamyl)-S-methylcysteine","Dihydroresveratrol 3-O-glucoside","1-(4-{[tert-Butyl(dimethyl)silyl]oxy}-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-{[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxyethyl]amino}ethan-1-ol","16-Phenoxy tetranor prostaglandin F2alpha methyl amide","4,7'-Epoxy-3'-methoxy-4',5,9,9'-lignanetetrol 9'-glucoside","1-O-E-Cinnamoyl-(6-arabinosylglucose)","Alanyl-gamma-glutamyl-lysine","(R)-6'-O-(4-Geranyloxy-2-hydroxycinnamoyl)-marmin","Octadecylamine","12-hydroxy-19-[(Z)-4-hydroxy-3-methylbut-2-enyl]-8,8,21,21-tetramethyl-5-(3-methylbut-2-enyl)-3,7,20-trioxahexacyclo[15.4.1.02,15.02,19.04,13.06,11]docosa-4(13),5,9,11,15-pentaene-14,18-dione","3-Phenylpropyl hexanoate","4-[5-[[4-[5-[Acetyl(hydroxy)amino]pentylamino]-4-oxobutanoyl]-hydroxyamino]pentylamino]-4-oxobutanoic acid","Leu-Met","10,11-Dihydro-12R-hydroxy-leukotriene E4","Malabaricone B","(3R,5R,8R,9S,10S,13S,14S,17R)-17-(1-hydroxyethyl)-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthrene-3,17-diol","Piperazine-2-carbonitrile","1-Methoxy-4-(1-phenylvinyl)benzene","7-Aminonimetazepam","Armillyl orsellinate","Methyl (9Z)-8'-oxo-6,8'-diapo-6-carotenoate","N-Acetylphenylalanine","2-hydroxy-1-[2-(hydroxymethyl)-2-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]cyclopropyl]-2-(1,3,11,16-tetrahydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)propan-1-one","Pergolide sulfone","(S)-Neomammein","JWH 018 7-hydroxyindole metabolite","Nitrobenzene","N-acetylleucyl-leucyl-methioninal","3-oxo-3-[[3,4,5-trihydroxy-6-[[7-hydroxy-4-[(Z)-5-hydroxy-3-methylpent-3-enyl]-4a,8,8-trimethyl-3-methylidene-2,4,5,6,7,8a-hexahydro-1H-naphthalen-2-yl]oxy]oxan-2-yl]methoxy]propanoic acid","phosphatidylcholine (1-18:2-2-18:2)","L-Tryptophyl-L-Threonine","2-Hydroxyoctanoic acid","cis-4-Octenedioic acid","5-[3-(4-Ethylnaphthalene-1-carbonyl)indol-1-yl]pentanoic acid","3-Oxo-alpha-ionol 9-[apiosyl-(1->6)-glucoside]","Acylcarnitine C14:3,COOH","(15Z)-9,12,13-Trihydroxy-15-octadecenoic acid","Desaminotyrosine","19-Hydroxy-4-androstene-3,17-dione","4-Hydroxytriamterene","Methyldopate","Glycylleucine","(R)-[(1R,2S,4S,5R)-5-ethenyl-1-oxido-1-azoniabicyclo[2.2.2]octan-2-yl]-(6-methoxy-1-oxidoquinolin-1-ium-4-yl)methanol","4-(Phenylmethyl)-1-piperazineacetic Acid 2-[[2-Hydroxy-3-(2-propen-1-yl)phenyl]","phosphatidylethanolamine (1-cis-vaccenoyl, 2-palmitoleoyl)","Di-n-hexyl phthalate","cis-9-Palmitoleic acid","8'-amino-1,1,4a,6-tetramethylspiro[3,4,6,7,8,8a-hexahydro-2H-naphthalene-5,2'-3,6-dihydrofuro[2,3-e]isoindole]-2,4'-diol","N-(4,6-dimethylpyrimidin-2-yl)-N'-[2-(4-methoxyphenyl)ethyl]guanidine","3-(4-Morpholino-1-methyl-1H-pyrazolo[3,4-d]pyrimidine-6-yl)phenol","Docosanamide","2-Amino-6-(methylthio)pyridine-3,5-dicarbonitrile","2-Deoxychamaedroxide","1-[(Furan-2-yl)methyl]-5-oxopyrrolidine-3-carboxylic acid","1-Oleoyl-2-oleoyl-3-gamma-linolenoyl-glycerol","Glutamylvaline","Acetylpterosin C","19-Hydroxydeacetylnomilinic acid 17-beta-D-glucopyranoside","Penicilloic V Acid","N-cyclohexyl-2-(N-(3-fluorophenyl)-2-(2-methyl-1H-imidazol-1-yl)acetamido)-2-(o-tolyl)acetamide","3-Hydroxydeca-4,6-dienoylcarnitine","Pipecolic acid","Phe-Val","3,5,5-trimethyl-4-[(E)-3-[3,4,5-trihydroxy-6-[(3,4,5-trihydroxyoxan-2-yl)oxymethyl]oxan-2-yl]oxybut-1-enyl]cyclohex-2-en-1-one","2-[4-(2-carboxy-5-oxopyrrolidin-1-yl)-6,6,9a-trimethyl-5-[(2E,4E,6E)-octa-2,4,6-trienoyl]oxy-1-oxo-4,5,5a,7,8,9-hexahydro-3H-benzo[e]isoindol-2-yl]pentanedioic acid","N-Desmethyl Ulipristal Acetate","Lysylisoleucine","N-(4-nitrophenyl)pyrrolidine-2-carboxamide","1-Hydroxy-13-(4-oxoquinazolin-3-yl)-10-propan-2-yl-8,11-diazatetracyclo[6.6.1.02,7.011,15]pentadeca-2,4,6-triene-9,12-dione","Ilomastat","Acrimarine J","Bicyclo[3.2.1]octane-1-carboxaldehyde, 2-[(3S,3aS,4S,7aR)-3-(beta-D-glucopyranosyloxy)octahydro-4,7a-dimethyl-1-oxo-4-isobenzofuranyl]-6-hydroxy-6-(hydroxymethyl)-, (1R,2R,5R,6R)-","(2S,3R,4S,5S,6R)-2-[4-[(3S,3aR,6R,6aR)-6-[3-methoxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol","Acrimarine N","Stachyose","Verimol A","1-Octen-3-yl primeveroside","5F-3,5-Ab-pfuppyca","1,3,8-Triazaspiro(4.5)decane-2,4-dione, 8-(phenylmethyl)-","N-(Naphthalen-1-yl)-1-pentyl-1H-indole-3-carboxamide","4-Hexyloxyphenol","Albanin E","Carbobenzyloxyglycylglycyl-L-proline benzyl ester","Eleutherazine B","N-Undecylbenzenesulfonic acid","5-(4-Butoxyphenyl)-3,5-dimethyl-2,4-imidazolidinedione","H-Asp(OBzl)-OH","Oxyacanthine","Undecanoylcholine [M]","Acuminoside","Unii-73hdp58zfk","(2S,3S)-2-[[(2S)-2-azaniumyl-3-phenylpropanoyl]amino]-3-methylpentanoate","(E)-3-[4-hydroxy-3-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)phenyl]prop-2-enoic acid","Garcinone D","Zolpidem","7-[2-(1,2-Dihydroxy-3-oxooctyl)-3,5-dihydroxycyclopentyl]hept-5-enoic acid","Dukunolide E","Garcinone C","LPC(16:0)","3-Cyclohexyl-2-hydroxypropanoic acid","(2R)-2-[[(2R)-2-amino-4-methylsulfanylbutanoyl]amino]-3-(1H-indol-3-yl)propanoic acid","(1S,3S,12S,14R,27S)-12-hydroxy-1,3-dimethyl-2,5,15,23,25-pentazaheptacyclo[12.10.2.12,5.06,11.015,24.017,22.012,27]heptacosa-6,8,10,17,19,21,23-heptaene-4,16,26-trione","7H-(1)Benzopyrano(3',2':3,4)pyrido(1,2-a)benzimidazole-6-carbonitrile, 3-(diethylamino)-7-imino-","Leucyl-leucyl-norleucine","(E)-2,6-Dimethyl-2,5-heptadienoic acid","PE(18:2(9Z,12Z)/18:3(6Z,9Z,12Z))","Cyclo(L-leucyl-L-phenylalanyl)","Cinitapride","6S,9R-Dihydroxy-4,7E-megastigmadien-3-one 9-[apiosyl-(1->6)-glucoside]","methyl (2S)-3-methyl-2-[(1-pentylindole-3-carbonyl)amino]butanoate","Allopurinol riboside","Estra-1,3,5-(10)-trien-17-one-3-oxyacetic acid","Piperolein B","(4Z,7Z,10Z,13Z,15E,19Z)-17-Oxodocosahexaenoic acid","Austocystinb","2-Amino-3-[4-[2-amino-3-phenylpropanoyl]oxyphenyl]propanoic acid","4-Benzyl-7-hydroxy-3-phenylcoumarin","2-Amino-5-[2-[[2,3-dihydroxy-2-(1-hydroxyethyl)butanoyl]oxymethyl]-4-hydroxyanilino]-5-oxopentanoic acid","[(E,6R)-6-hydroxy-6-[(8S,9R,10R,13R,14S,17R)-16-hydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthren-17-yl]-2-methyl-5-oxohept-3-en-2-yl] acetate","Dulciol B","(-)-Kanzonol F","N-(2-benzamido-1,3-benzothiazol-6-yl)adamantane-1-carboxamide","9-Benzyl-5-[(furan-2-ylmethyl)amino]-7,8,9,10-tetrahydro[1,2,4]triazolo[3,4-a][2,7]naphthyridine-6-carbonitrile","Benzamide, N-(4-amino-2-chlorophenyl)-5-chloro-2-hydroxy-","Methyl 4-(4,6-dihydroxy-5-methoxy-2,5-dimethyl-3-oxocyclohexen-1-yl)oxy-2-hydroxy-3,6-dimethylbenzoate","3-Oxopentanoic acid","Neoacrimarine G","Valyltryptophan","3-(N-morpholino)propanesulfonate","11beta,21-Dihydroxypregn-4-ene-3,20-dione 21-acetate","Leucyl-Asparagine","2-[[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-6-(trifluoromethyl)-1H-benzimidazole","naphthalen-2-yl1-(2-fluorophenyl)-1H-indazole-3-carboxylate","2-Hydroxycarbazole-3-carboxylic acid 4-chloroanilide","Pinolenic acid","5-Oxo-prolyl-glycyl-arginine-4-nitroanilide","12b-Acetoxy-3b-hydroxy-4,4,14-trimethyl-7,11,15-trioxochol-8-en-24-oic acid, 9CI","(8Z,22Z)-4-hydroxy-2-oxa-11,16,20-triazatricyclo[22.2.2.13,7]nonacosa-1(26),3,5,7(29),8,22,24,27-octaene-10,21-dione","Licochalcone A","6beta-Naltrexol","Leukotriene F4","2-(2-Butoxyethoxy)acetic acid","5-Methyl-2-oxo-1,3-oxazolidine-4-carboxylic acid","6-Chloro-3-(trifluoromethyl)pyridine-2-carbonitrile","2-(((6-Chloropyridin-3-yl)methyl)thio)ethanamine","Isolariciresinol","17beta-Estradiol 17-(beta-glucuronide)","1,2-Diphenyl-3-pyrrolidin-1-ylpropan-1-one","Kaempferol-3-O-(6'''-trans-p-coumaroyl-2''-glucosyl)rhamnoside","trans-2-Bromo-1-indanol)","Ergocristin","jwh 018 n-(2,2-dimethylpropyl) isomer","Argenteane","2-(4-Methylphenyl)-1-(1-pentylindol-3-YL)ethanone","phomamide","Pyrraline","4-Hydroxytetradecanedioylcarnitine","Norlaudanine","Veratraldehyde azine","Vanillin propylene glycol acetal","beta-hydroxyprednisolone","4-hydroxy-3-[2-(1H-imidazol-5-yl)ethyl]-4,5,5-trimethyl-1,3-oxazolidin-2-one","propan-2-yl (1S,2R,3S,5R)-3-benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate","N-Trityl-homoserine","(2R)-2-[[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid","3-(1H-benzimidazol-2-yl)propanehydrazide","Leukotriene D5","4-phenylpyrimido[1,2-a]benzimidazol-2(1H)-one","Ixocarpanolide","6-(3,7-Dimethyl-2,6-octadienyl)-2,3-dihydro-7-hydroxy-5-methoxy-2-(2-phenylethyl)-1H-isoindol-1-one, 9CI","Isorhamnetin 3-galactoside","Diosbulbin F","(2R,3R,4S,5S,6R)-2-octoxy-6-[[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxymethyl]oxane-3,4,5-triol","Diosbulbin E","6-[(8a-Carboxy-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl)oxy]-4-[2-carboxy-1-(carboxymethoxy)-2-hydroxyethoxy]-3,5-dihydroxyoxane-2-carboxylic acid","5-oxo-prolyl-valine","4-fluoro-N-(1H-indol-5-yl)benzamide","8-Methoxy-3-methylbenzo[a]anthracen-1-ol","13-Ethenyl-5,7,9,11,13-pentamethyl-2-oxa-18-azahexacyclo[20.2.2.13,10.04,9.016,20.014,27]heptacosa-1(24),11,22,25-tetraene-15,17,19-trione","2-(4-Tert-butylphenyl)quinoline-4-carboxylic acid","2-{[(4-Bromo-2-fluorophenyl)methyl]sulfanyl}acetic acid","2alpha-Methylpregn-4-ene-3,11,20-trione","2,5-Difluorobenzaldehyde","Methyl 2-(3-ethenyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl)-3-methoxyprop-2-enoate","Leukotriene C5","6-Ethoxy-4-methyl-3-phenylcoumarin","gamma-Glu-epsilon-Lys dizwitterion","11,12-Dihydroxy-7,14-dimethoxy-8,11,13-abietatrien-20,6-olide","3-Aminoazepan-2-one","H-Arg(NO2)-Obzl","[(1R,2R,3E,5R,7S,9E,11R,12S,15R,16S)-16-Benzyl-5,12-dihydroxy-5,7,13,14-tetramethyl-6,18-dioxo-17-azatricyclo[9.7.0.01,15]octadeca-3,9,13-trien-2-yl] acetate","Pro-Arg","N-(2-Fluorenyl)-para-toluamide","Dulxanthone E","19-Oxo-deoxycorticosterone","TG(18:2(9Z,12Z)/18:2(9Z,12Z)/18:3(6Z,9Z,12Z))","N-Eicosapentaenoyl Tryptophan","Larreatricin","5-[[4,5-dihydroxy-6-[(6E)-8-methoxy-3,7-dimethyl-8-oxoocta-1,6-dien-3-yl]oxy-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]methoxy]-3-hydroxy-3-methyl-5-oxopentanoic acid","2,3-dinor-thromboxane B2","2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]propanoic acid","4-[2-[[(1S,2R)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]amino]ethyl]phenol","(threonyl)adenylate","2-Benzamido-4-methylpentanoic acid","Monoethyl fumarate","rac trans-3-Hydroxy-1-methyl-2-pyrrolidinone-5-(3-pyridinyl)carboxylic Acid","2-(2-methoxyphenyl)-1-(1-pentylindol-3-yl)ethanone","Harringtonine","4-[5-(Hydroxymethyl)-8-methyl-3-oxabicyclo[3.3.1]non-7-en-2-yl]phenol","3-Hydroxy-2H-pyran-2-one","Corynanthine","N-oleoylglycine","5-(2-(Furan-3-YL)ethyl)-8A-(hydroxymethyl)-5,6-dimethyl-3,4,4A,6,7,8-hexahydronaphthalene-1-carboxylic acid","Medazomide","11-Dehydrocorticosterone","H-Glu-Val-D-Phe-OH","2-bromo-1H-pyrrolo[2,3-b]pyridine","4-Oxo-L-proline","Asp-Tyr","(2E,4E)-12-hydroxy-13-(hydroxymethyl)-14-methoxy-3,5,7-trimethyl-14-oxotetradeca-2,4-dienoic acid","6-(2-(tert-Butyl)-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl)quinoxaline","5-Aminolevulinic acid","Methyl Decanoate","Caprylic acid","5-[4-(4-Hydroxyphenyl)phenyl]benzene-1,3-diol","Rubraflavone B","N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]amino]benzoyl]glutamic acid","14-Acetyloxy-14-methoxycarbonyl-5,9-dimethyltetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acid","Kuwanon E","Carbobenzoxyglutamine","Tyr-Asn","Tyr-Asp","(4-Fluorophenyl)(2-(4-methoxyphenyl)-1H-imidazol-4-yl)methanone","L-2-Cyanophenylalanine","Pro-Phe","Rubraflavone C","(3-Oxopiperazin-2-yl)acetic acid","Harderoporphyrinogen","Phenethyl sophoroside","Methionyl-Glutamate","3-(2-Oxocyclohexyl)propanoic acid","Tryptophan Tryptophan dipeptide","Isonoruron","N-Acetylglycylglycine","7-[5-[Oct-2-en-1-ylidene]-4-oxocyclopent-2-en-1-yl]hept-5-enoylcarnitine","1-(9Z-tetradecenoyl)-sn-glycero-3-phosphocholine","2-Bromo-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol","6alpha-Fluoroprednisolone","(1S,3R,6R,7S,8S,9R,10S,13S,16S,17R)-8-tert-butyl-6,9,12,17-tetrahydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione","N-Lactoylglycine","2-(Dimethylamino)-6-Methyl-Pyrido[4,3-D]pyrimidin-5-One","Trp-Phe","alpha-Neup5Ac-(2->6)-D-Galp","2-Hydroxy-4-methoxy-3,5-bis(3-methylbut-2-enyl)-6-(2-phenylethyl)benzoic acid","3-aminotridecan-4-one","2-Acetyltetrahydroxybutylimidazole, (1R,2S,3R)-","Pelanserin","16-phenyl tetranor Prostaglandin E2","N-[(4-hydroxy-2-iodo-5-methoxyphenyl)methyl]-8-methylnonanamide","9(10)-EpOME","Difenoxuron","(2R)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid","Vincamine","gamma-Glu-Ser-Gly","LPC(18:0/0:0)","Cyclo(Gly-Glu)","4-Ethenyl-21-hydroxy-6,8,10,12-tetramethyl-15,23-dioxa-25-azaheptacyclo[19.2.2.216,19.13,7.01,22.08,13.014,28]octacosa-5,16(27),17,19(26)-tetraene-2,24-dione","Bis(benzyloxy)(diisopropylamino)phosphine","Isoleucine","4-Hydroxytamoxifen","2,6-Difluoro-4-[4-[4-(4-methylpiperazin-1-yl)phenyl]pyridin-3-yl]phenol","Methionyl-Tryptophan","6-chloro-N-cyclohexyl-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine","Acetylleucyl-leucyl-norleucinal","Trp-Ala","Pyruvate","Fructose","(3R)-3-hydroxy-12'-apo-beta-carotenal","9-Methoxy-4,4-dimethyl-13-phenyl-6,14-dioxatetracyclo[8.4.0.02,7.03,5]tetradeca-1,7,9-trien-11-one","N-acetyl-5-methoxykynurenamine","Taurolithocholate sulfate","N-[(9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-1-oxo-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2', 1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-11-yl]-N-methyl-benzamide","Blumenol C O-[apiosyl-(1->6)-glucoside]","Hydroxyprolyl-Tyrosine","7-Bromopyrrolo[1,2-A]quinoxalin-4(5h)-One","Asp-Leu","Nbeta-aspartyl-phenylalanine methyl ester","tetranor-PGAM","Caproic acid","1-[4-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy]-3-methoxyphenyl]ethanol","[(6E,10Z)-10-(acetyloxymethyl)-6-formyl-3-methylidene-2-oxo-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-4-yl] 2-methylbutanoate","1-(3,4-Dichlorobenzyl)piperazine","4-(chloromethyl)-7-hydroxy-8-methyl-2H-chromen-2-one","Desthiobiotin","(2R,3S,4S,5R,6S)-2-[[(2R,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxymethyl]-6-(1H-indol-3-yloxy)oxane-3,4,5-triol","2-Hydroxy-4-methoxy-7-methyl-7,8,9,10,11,12,13,14-octahydro-6-oxabenzocyclododecen-5-one","Glycerol 1,3-di-(9Z,12Z-octadecadienoate) 2-hexadecanoate","2-[[2-[(2-Amino-3-phenylpropanoyl)amino]acetyl]amino]-3-phenylpropanoic acid","N6-benzyloxycarbonyl-lysine","8-[5-(5,7-Dihydroxy-4-oxo-2,3-dihydrochromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one","methylglutaconyl hydroxy ornithine","b-D-Xylopyranosyl-(1->4)-a-L-rhamnopyranosyl-(1->2)-D-fucose","(3S)-1H,2H,3H,4H,9H-pyrido(3,4-b)indole-3-carboxylic acid","Canarigenin 3-[glucosyl-(1->4)-6-deoxy-alloside]","Sambacin","Ser-Phe","22-Hydroxy Mifepristone","1-20:0-2-18:2-phosphatidylethanolamine","8-keto-7-aminoperlagonate","(2E,4E,10Z)-N-(2-methylpropyl)hexadeca-2,4,10-trienamide","N-(furan-2-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine","N-cyclohexyl-N'-(tetrahydro-2-furanylmethyl)urea","Dextilidine","Tyramine","Erysubin F","(4R)-4-amino-5-[[(1R)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-oxopentanoic acid","Quinaprilat","Arnicolide C","4-Isopropyl-4'-methylchalcone","Methyl 1-(cyclohexylmethyl)indole-3-carboxylate","3-Aminopyrazin-2-ol","4-Deoxyphysalolactone","1-alpha-Acevaltrate","Glyco-beta-muricholic acid","(2S)-2-[[(2S)-2-azaniumyl-3-(1H-indol-3-yl)propanoyl]amino]-4-methylsulfanylbutanoate","5-Benzoylamino-isophthalic acid","1-(1-(9-Methyl-9-azabicyclo[3.3.1]nonan-3-yl)indolin-2-one","4H-1-Benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (2S)-","Argatroban anhydrous, (21R)-","2,4,5-Trihydroxyphenylalanine","Isopetasoside","Dorrigocin B","Prednicarbate","alpha-Pbt","2-[2-Hydroxyethyl-(1-methylpyrazolo[3,4-d]pyrimidin-4-yl)amino]ethanol","Napropamide","12,13-Epoxyoctadeca-9,11-dienoic acid","N-[4-(dimethylamino)phenyl]-N'-(4-methoxyphenyl)urea","[(2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[2-(4-hydroxyphenyl)ethoxy]oxan-2-yl]methyl 2-(2-oxo-1,3-dihydroindol-3-yl)acetate","2,3-Dinor-8-iso prostaglandin F1alpha","S-Octyl GSH","8,11-Tridecadienoic acid, 13-(3-pentyl-2-oxiranyl)-, (8z,11z)-","Royal jelly acid","Suberoyl-carnitine","Quillaic acid 3-[rhamnosyl-(1->3)-[galactosyl-(1->2)]-glucuronide]","2-Heptylbenzothiazole","Non-5-enedioylcarnitine","1beta,3alpha,7alpha-Trihydroxy-5beta-cholan-24-oic Acid","2-Fluoro-4-biphenylboronic Acid","8beta-Angeloyloxy-15-hydroxy-1alpha,10R-dimethoxy-3-oxo-11(13)-germacren-12,6alpha-olide","Paramethasone","1-Methyl-1H-pyrazolo[3,4-d]pyrimidin-4-ol","3-Hydroxyoctanoic acid","2-(Hydroxymethyl)-6-{[2,3,5-trihydroxy-6-(hydroxymethyl)-4-{[4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}cyclohexyl]oxy}oxane-3,4,5-triol","2-(3,4-Dimethoxyphenoxy)-6-[(3,4,5-trihydroxyoxan-2-yl)oxymethyl]oxane-3,4,5-triol","1,1-Dioxo-1lambda6-thiolane-3-carboxylic acid","Isolariciresinol 9-O-beta-glucoside","Benzyl b-sophoropyranoside","2-Oxazolidinone, 3-amino-5-(4-morpholinylmethyl)-","Tryptophan","Triacetate","Methyl 4-[6-[4-(methoxycarbonylamino)phenyl]-4-morpholin-4-ylpyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate","(6E,12E)-8,9,16,18-tetrahydroxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),6,12,15,17-pentaen-2-one","Rosellichalasin","Dodecyl isobutyrate","Tyr-Tyr","2,6-Di-tert-butyl-4-methylphenol","4-(1H-indol-3-yl)-1-(morpholin-4-yl)butan-1-one","Br-Xanthone A","6-Prenylpinocembrin","(E,3R,5S)-7-[4-(4-fluorophenyl)-6-[(2S)-1-hydroxypropan-2-yl]-5-(methoxymethyl)-2-propan-2-ylpyridin-3-yl]-3,5-dihydroxyhept-6-enoic acid","ergotamam","Asparagine","10-Formyltetrahydropteroyldiglutamate","Cibaric acid","Lafutidine","Tanshinone Iia","Edulisin II","(E)-2'-Geranyl-3',4',7-trihydroxyflavanone","4'-Chloro-4-biphenylol","Daidzin 4'-O-glucuronide","[4,5-dihydroxy-2-(hydroxymethyl)-6-(2,3,4,5,6-pentahydroxycyclohexyl)oxyoxan-3-yl] 4-hydroxy-2-methoxy-6-methylbenzoate","4-hydroperoxyoctadeca-t-2-nonenal","Aldosterone","3-(2,5-Dioxopyrrolidin-1-yl)propanoic acid","Cpa(18:2(9Z,12Z)/0:0)","(1-hexyl-5-phenyl-1H-pyrrol-3-yl)(naphthalen-1-yl)methanone","C20915","Adenosine monophosphate (AMP)","2-Palmitoyl-sn-glycero-3-phosphocholine","Pentafluorobenzaldehyde","(1E,4Z,6E)-5-Hydroxy-1,7-Bis(4-Hydroxyphenyl)Hepta-1,4,6-Trien-3-One","2,2-Bis(3-amino-4-hydroxylphenyl)propane","7-Methylxanthine","Garcimangosone C","3,11-Dihydroxytetradecanoylcarnitine","2-Amino-3-(4-(4-hydroxyphenoxy)phenyl)propanoic acid","2-Amino-4,6-dichloropyrimidine-5-carboxaldehyde","N'-[2-(Oxidanylcarbamoyl)phenyl]-N-phenyl-octanediamide","beta-Ala-Phe","2-(Pyridin-4-yl)-1,3-thiazole-4-carboxylic acid","1-(3,4-Dihydroxyphenyl)-2-pyrrolidin-1-yl-pentan-1-one","Cornudentanone","(E)-8-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-2,6-dimethyloct-6-enoic acid","(4-Ethyl-1-naphthalenyl)(1-(5-fluoropentyl)-1H-indol-3-yl)methanone","Dicentrine","[(2R,3S,4R,5S,6R)-2-(acetyloxymethyl)-4,5-dihydroxy-6-[(2S,3R)-2,3,4-trihydroxybutoxy]oxan-3-yl] hexanoate","3,5-Dihydroxydodecanoylcarnitine","(3R,7R,8R,8aS)-3,4'-dihydroxy-4,4,7,8a-tetramethylspiro[2,3,4a,5,6,7-hexahydro-1H-naphthalene-8,2'-7,8-dihydro-3H-furo[2,3-e]isoindole]-6'-one","Ser-Leu","Caryoptosidic acid","2,3,5-Trimethyl-6-[3-Oxo-3-(Piperidin-1-Yl)propyl]-7h-Furo[3,2-G][1]benzopyran-7-One","(1R,3S,6S,7E,13S,16R,17R,21S,22S)-17-[(2R,4R,5S,6R)-5-[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-28-hydroxy-3,22-dimethyl-23,26-dioxo-24,27-dioxapentacyclo[23.2.1.01,6.013,22.016,21]octacosa-4,7,14,25(28)-tetraene-4-carboxylic acid","N1-citryl-N3-dec-2-enoyl-N3-hydroxy-1,3-diaminopropane","Naloxone N-Oxide","Threonylmethionine","Tetradecylamine","Pyruvaldehyde","gamma-Glu-Thr-Gly","(6E)-Piperamide-C7:1","N-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide","N-(4-oxo-3,1-benzothiazin-2-yl)-4-phenylbutanamide","2-[[2-[(2-Amino-3-methylpentanoyl)amino]acetyl]amino]-3-methylpentanoic acid","Sedoheptulosan","2-Amino-N-benzyl-3-(1H-indol-3-yl)-propionamide","Remifentanil","sphing-8-enine","Citramalic acid","Docosa-7,10,13-trienoylcarnitine","(9Z,11E,13E,15Z)-4-Oxo-9,11,13,15-octadecatetraenoic acid","[(4E,6Z,8S,9S,10Z,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-enylamino)-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate","Ribose","Leu-Ser","3,4-Dihydroxyallylbenzene 3,4-di-O-glucoside","Val-Gln","Kelampayoside A","Pimelylcarnitine (C7:0,COOH)","alpha-Methylthiofentanyl","Acylcarnitine C15:2,COOH","Vomifoliol 9-[xylosyl-(1->6)-glucoside]","Trp-Tyr","Pro-Pro","Arg-Ala","4-Fluorooxane-4-carboxylic acid","Metapristone","Cortisol 21-mesylate","Tyrosyl-Phenylalanine","2-[(3,17-Dihydroxy-13-methyl-8,9,11,12,14,15,16,17-octahydro-7H-cyclopenta[a]phenanthren-6-ylidene)amino]oxyacetic acid","Artemoin C","Meteloidine","Dethiobiotin","3-Hydroxy-2-[[3-(3-hydroxy-6-methyloctanoyl)oxy-8-methylnonanoyl]amino]propanoic acid","N-(2,3-Dimethylphenyl)-4-methylbenzenesulfonamide","Methyl ent-16a-acetoxy-19-oxo-17-kauranoate","3-Hydroxystanozolol glucuronide","Lobaric Acid","2-(4-Methoxyphenyl)-1-(1-pentylindol-3-YL)ethanone","Geranyl linalool","Ehretioside B","Desmethylcarvedilol","Trp-Asp","2,8-diamino-5-[(E)-2-[1-(5-amino-5-carboxypentyl)-3,5-bis(3-amino-3-carboxypropyl)pyridin-1-ium-2-yl]ethenyl]nonanedioic acid","(glutathion-S-yl)-4-hydroxy-2-nonenal","5-Oxo-L-prolyl-L-proline","5,6-Dihydroxyprostaglandin F1a","3-[(2,4-Dimethoxyphenyl)amino]-3-oxopropanoic acid","epoxy-maresin","Methyllycaconitine Perchlorate, Delphinium sp.","Norbuprenorphine","2,4-Dodecadienamide, N-(2-methylpropyl)-, (2E,4E)-","Spinacoside D","N-(1-Deoxy-1-fructosyl)phenylalanine","Thr-Phe","cyclo(D-tyrosyl-arginyl-arginyl-3-(2-naphthyl)alanyl-glycyl)","Acidissiminol","3b-Hydroxy-6b-(2,3-epoxy-2-methylbutanoyloxy)-7(11)-eremophilen-12,8b-olide","N-[2-(5,6-Dimethyl-1h-Benzimidazol-2-Yl)ethyl]-4-(4h-1,2,4-Triazol-4-Yl)benzamide","8-Oxononanoic acid","2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline","Hepps","1-(2-Amino-3-phenylpropanoyl)-4-hydroxypyrrolidine-2-carboxylic acid","(19-Hydroxy-4,5,24-trimethyl-22-oxo-26,27-dioxa-7-azaheptacyclo[21.3.1.01,20.04,19.05,16.06,14.08,13]heptacosa-6(14),8,10,12,20-pentaen-24-yl) acetate","2-[4-Hydroxy-2-(hydroxymethyl)-6-[(10,14,16,20-tetramethyl-22-azahexacyclo[12.10.0.02,11.05,10.015,23.017,22]tetracos-4-en-7-yl)oxy]-5-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol","Glu-Leu","3-Hydroxy-4-(4-hydroxybenzoyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid","6,2',4'-Trimethoxyflavone","6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid, (S)-","Phorbol 12,13-dibutanoate","3-Hydroxy-7,8,3'-trimethoxyflavone","4-chloro-N'-(2-chloroacetyl)benzohydrazide","5-(3,4-Dihydroxyphenyl)-6,7-dimethyl-5,6,7,8-tetrahydronaphthalene-2,3-diol","Tyrosylhydroxyproline","capsiconiate","(1S,4R,7S,9R)-4-benzyl-9-(2-methylbut-3-en-2-yl)-2,5,16-triazatetracyclo[7.7.0.02,7.010,15]hexadeca-10,12,14-triene-3,6-dione","Fulvestrant sulfone","(10e,15z)-9,12,13-Trihydroxyoctadeca-10,15-dienoic acid","Ketologanic acid","caffeoylserotonin","(14alpha,17beta,20S,22R)-14,20-Epoxy-17-hydroxy-1-oxowitha-3,5,24-trienolide","Methyl 1-((2'-cyano(1,1'-biphenyl)-4-yl)methyl)-2-ethoxy-1H-benzimidazole-7-carboxylate","5-O-Methylembelin","DG(18:4(6Z,9Z,12Z,15Z)/15:0/0:0)","2-(5-chloro-2-methyl-1H-indol-3-yl)ethanamine","[4]-Gingerdiol 3,5-diacetate","estradiol alone","3-Hydroxy-6,8-dimethoxy-7(11)-eremophilen-12,8-olide","(1R,2E,7R,10E,12S,13S,15R)-12,15-dihydroxy-7-methyl-8-oxabicyclo[11.3.0]hexadeca-2,10-dien-9-one","Leu-Asn","Troxipide","Glycolide","pyridin-2-ylmethyl N-(3-chlorophenyl)carbamate","4,4'-Dihydroxy-3,3'-dimethoxy-9,9'-epoxylignan","Pentobarbital","1-Carbobenzoxy-2-piperidinecarboxylic Acid","Mesaconic acid","N6-Benzyladenine","D-xylo-Pentitol, 1,4,5-trideoxy-1,4-imino-5-(4-methoxyphenyl)-, 3-acetate","Desomorphine","N-Desmethyl imatinib","D-erythro-Sphingosine C-20","4-allyl-5-(2-methylphenyl)-4H-1,2,4-triazole-3-thiol","6,7-Bis(2-methoxyethoxy)quinazolin-4(3H)-one","4-amino-3-hydroxyhexadecanoate","N-Isopropylethylenediamine","2-(Aminomethyl)pyrazine","5-(4-chlorophenyl)-N-(4-piperazin-1-ylphenyl)-N-(pyridin-2-ylmethyl)furan-2-carboxamide","n-arachidonylethanolamine","2-[[2-[[2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]acetic acid","Fludrocortisone Acetate","Val-Ala","3-tert-butyl-1-methyl-1H-pyrazole-5-carboxylic acid","4-Methyl-6-(1-methyl-1H-benzimidazol-2-yl)-2-propyl-1H-benzimidazole","2-Ethyl-3-oxo-1,2,3,4-tetrahydroquinoxaline-6-carboxylic acid","N-Acetylsphinganine","(2R,3R)-1-methyl-5-oxo-2-(pyridin-3-yl)pyrrolidine-3-carboxylic acid","Anhydrocinnzeylanol","Fradiamine A","Phenylalanylglutamine","3-hydroxyphenylpropionylglycine","3,4-Diphenyl-6-methylcoumarin","7-Hydroxychroman-2-one","Dodeca-3,6,9-trienoylcarnitine","3-Chloro-4-fluorophenylhydrazine","Acylcarnitine C16:2,COOH","2-(Hydroxymethyl)-6-[[3,4,5-trihydroxy-6-(19-hydroxy-4',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-oxane]-16-yl)oxyoxan-2-yl]methoxy]oxane-3,4,5-triol","(2S)-3-methyl-2-[[(2R)-5-oxopyrrolidine-2-carbonyl]amino]butanoic acid","4-Hydroxy-1-propanoylproline","5S-Hydroxy-6R-(S-gamma-glutamylcysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid","Anhydronotoptol","Val-Phe","N-phenyl-2-[4-(pyridin-2-yl)piperazin-1-yl]acetamide","Acylcarnitine C14:0,COOH","Altenuene","Lemmatoxin","5-phenyl-3-prop-2-enyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol","5'-Hydroxyphenyl Carvedilol","1H-Purine, 6-[(1-phenylethyl)thio]-","5-(2-Diethylamino-ethyl)-2-(5-fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-3-methyl-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one","3,9-Dihydroeucomin","His-Val","Blumealactone A","Dihydro-¦Â-erythroidine (hydrobromide)","11-alpha-O-beta-D-Glucopyranosyl-16alpha-O-methylneoquassin","Ochromycinone","3-Hydroxytetradec-4-enedioylcarnitine","Oleanoglycotoxin-A","g-Chaconine","1-hydroxy-4-[(4-hydroxy-2,2-dimethyl-1-oxo-3,3a-dihydroimidazo[1,2-a]indol-4-yl)methyl]-1-propan-2-yl-2,4-dihydropyrazino[2,1-b]quinazoline-3,6-dione","sphingofungin D","3'-Hydroxylarreatricin","9-[(3aR,4S,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]-2-amino-3H-purin-6-one","L-gamma-Glutamyl-S-((1R,2E,4E,6Z,9Z)-1-((1S)-1-hydroxy-5-methoxy-5-oxopentyl)-2,4,6,9-pentadecatetraen-1-yl)-L-cysteinylglycine","Linalool oxide D 3-[apiosyl-(1->6)-glucoside]","H-DL-Arg-Gly-DL-Arg-OH","Sativic acid","Tyrosylalanine","Ribothymidine","Cytochalasin D","Androst-4-ene-3,6,17-trione","S-(Prostaglanding A1)-glutathione","Esprocarb","3-[6-[(E)-4,6-dimethyloct-2-en-2-yl]-5-methyloxan-2-yl]-4-hydroxy-5-(4-hydroxyphenyl)-1H-pyridin-2-one","(-) Syringaresinol","(3Z)-3-Dibenz(b,e)oxepin-11(6H)-ylidene-N-methyl-1-propanamine","Ketoprofen","cis-Hexahydro-N-(4-chlorophenyl)phthalamic acid","Buxifoliadine A","Dihydroxyoctadecenoic acid","2-Methyl-3-[(tetrahydro-2-furanylcarbonyl)amino]benzoic acid","1-[(1-ethyl-3,5-dimethyl-1H-pyrazol-4-yl)sulfonyl]piperidine-4-carboxylic acid","Fluvoxamine Acid","[5-Chloro-2-(4-propionylpiperazin-1-yl)phenyl]amine","21-Deacetoxy 11-Oxodeflazacort","Clusiacyclol A","8-Acetamido-2-methyl-7-oxononanoic acid","Ampeloside Bs1","Cinereain","Fusidic Acid","Glyceric acid","Narceine","1-[3-methoxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxyphenyl]ethanone","Histidylisoleucine","rac-2-Despiperidyl-2-amino Repaglinide","4-(Trifluoromethyl)piperidine","11-Oxo-androsterone glucuronide","gamma-glutamyl-leucine","2-(6-oxo-1-oxaspiro[2.5]octa-4-glucosyl)-6-hydroxy-1-benzofuran-3-one","6,7-Diethoxy-4-methylcoumarin","Trilinolein","Pyripyropene A","Hydroxybutorphanol","2,11-Dimethoxy-9-(2-methylbut-3-en-2-yl)-14-propan-2-yl-2,13,16-triazatetracyclo[7.7.0.01,13.03,8]hexadeca-3,5,7,10-tetraene-12,15-dione","N-[7-(1H-Indol-3-ylmethyl)-3-(1-methylethyl)-5,8-dioxo-2-oxa-6,9-diazabicyclo[10.2.2]hexadeca-10,12,14,15-tetraen-4-yl]-3-methyl-2-(methylamino)butanamide, 9CI","2,4-Di-tert-butylphenol","Amphibine H","N-Stearoyl Threonine","N-[2-[4-(5-chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]-1-methylethyl]-2-naphthalenecarboxamide","1,2,10-Trihydroxydihydro-trans-linalyl oxide 7-O-beta-D-glucopyranoside","[(3R,3aR,4S,9bR)-9-(hydroxymethyl)-3,6-dimethyl-2,7-dioxo-3,3a,4,5,9a,9b-hexahydroazuleno[4,5-b]furan-4-yl] 2-(4-hydroxyphenyl)acetate","Gambogic Acid","Uridine","5-(3-((quinolin-8-yloxy)carbonyl)-1H-indol-1-yl)pentanoicacid","Glutamic acid diethyl ester","3,7-Dihydro-8-((2-hydroxyethyl)amino)-1,3,7-trimethyl-1H-purine-2,6-dione","17-Methylene-4-androsten-3-one","4-(Dodecylamino)Phenol","(3R,4R)-3,4-dihydroxyoxolan-2-one","O-Acetylpsilocin","2-[(2,2-diphenylacetyl)amino]benzoic Acid","13-Hydroxydihydromelleolide","[3-(3-carbamoylphenyl)phenyl] N-(6-phenylhexyl)carbamate","2-(3,4-Dihydroxy-2,2-dimethyl-3,4-dihydrochromen-6-yl)-7-hydroxy-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one","Opiniazide","Glaudine","1-cis-vaccenoyl-2-palmitoleoyl-sn-glycerol-3-phosphate","Beclomethasone","Pyridinoline","Ethyl apovincaminate","N,N'-bis-(4-Ethoxyphenyl)formamidine","Acetamide, N-hydroxy-N-(1-(4-(phenylmethoxy)phenyl)ethyl)-","Beta-Asarone","1-16:0-2-18:3-phosphatidylethanolamine","2-phenyl-N-(1-phenylethyl)quinoline-4-carboxamide","Tetradeca-7,9,11-trienoylcarnitine","Ile-Ser","(Z)-7-[(2R)-2-amino-2-carboxyethyl]sulfanyl-2-[[(1R)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoic acid","(1S,9R,11S,14S,15S)-15-methyl-9-[9-(4,4,5,5,5-pentafluoropentanesulfinyl)nonyl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-triene-5,14-diol","3-(4-Carboxybenzylidene)camphor","Suberylglycine","2,3-dihydroxy-4-methyloct-6-enoate","(2R,3R,4R,5R,6S)-2-[[(2R,3S,4S,5R,6R)-6-[1,7-bis(4-hydroxyphenyl)heptan-3-yloxy]-3,4,5-trihydroxyoxan-2-yl]methoxy]-6-methyloxane-3,4,5-triol","Deoxycohumulone","N-(2-bromophenyl)pyridine-4-carboxamide","4-Propanoyl-HT2 toxin","4-methyl-N-(4-nitrophenyl)piperazine-1-carboximidothioic acid","2,4-Dihydroxybutanoic acid","N-[(benzyloxy)carbonyl]glycylglycylnorleucine","3,8-dihydroxy-3,8-dimethyl-5-propan-2-ylidene-1,2,3a,4,7,8a-hexahydroazulen-6-one","Dibutyl sulfosuccinate","5-Hydroxy-2-hydroxymethylpyridine","D-Lysergic acid N,N-diethylamide","delta6-Testosterone enanthate","Malaoxon","5-chloro-2,4-dihydroxy-6-methyl-3-[(2E,4E)-3-methyl-5-(1,2,6-trimethyl-5-oxocyclohex-3-en-1-yl)penta-2,4-dienyl]benzaldehyde","Ethyl 2-hydroxy-3-(3-indolyl)propanoate glucoside","Phe-Pro","Auraptene","methionyl-alanyl-alanine tripeptide","1-[2-(1H-Imidazol-4-yl)ethyl]-3-phenethylthiourea","RCTR3","(+/-)14(15)-Eet-SI","Saucernetin","Mannose","Biotin sulfoxide","4-[(E)-3-[4,5-dihydroxy-6-(hydroxymethyl)-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxybut-1-enyl]-4-hydroxy-3,5,5-trimethylcyclohex-2-en-1-one","LPE(16:0)","Glycylproline","(3R)-5-(2-fluorophenyl)-3-(1H-indol-3-ylmethyl)-1-methyl-3H-1,4-benzodiazepin-2-one","Forsythin","Diphenoxylate","N-cyclooctyl-4-methylbenzenesulfonamide","Biapigenin","Triethylamine","Forasartan","8-Hydroxy-3-(7-hydroxyheptyl)-6-oxo-3,4-dihydroisochromene-7-carboxylic acid","(5Z)-7-((1S,2R,3R,4R)-3-((2-((Phenylamino)carbonyl)hydrazinyl)methyl)-7-oxabicyclo(2.2.1)hept-2-yl)-5-heptenoic acid","Mitomycin C","5,13,15-Trihydroxy-9-methyl-10-oxabicyclo[10.4.0]hexadeca-1(12),13,15-triene-3,11-dione","Atalaphylline","JWH 250 5-hydroxyindole metabolite","N,N'-Diacetyllysine","Sorbitan laurate","3-[(1E,3E)-hepta-1,3-dienyl]pentanedioic acid","Pubescine","Acylcarnitine C19:0,COOH","(4-Benzylpiperidin-1-yl)(2-fluorophenyl)methanone","[3,4,5-Trihydroxy-6-[(3,4,5-trihydroxyoxan-2-yl)oxymethyl]oxan-2-yl] 2,6,6-trimethylcyclohexene-1-carboxylate","Tubulosine","1-Isobutyl-5-methylpyrimidine-2,4(1h,3h)-dione","[(1R,13R)-13,24-dimethyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-2,4(8),9,14(22),15,17(21)-hexaen-12-yl] acetate","Octa-2,6-dienoylcarnitine","3-(1,3-Benzodioxol-5-ylmethyl)-4-[(3,4,5-trimethoxyphenyl)methyl]oxolan-2-one","Dodecylbenzenesulphonic acid","17beta-Carboxy-17alpha-formyloxy Dexamethasone","1beta-Acetoxyeudesma-4(15),7(11)-dien-8alpha,12-olide","Diisononyl phthalate","2-[(2-Methoxyphenyl)amino]pyridine-3-carboxylic acid","Raltegravir","(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-6b-Acetyl-5-hydroxy-4a,6a,8-trimethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]oxazol-2-one","MAM-2201 N-(4-hydroxypentyl)metabolite","Obscurolide A1","Semilepidinoside B","Ethyl 8-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate","Arg-Gly","1-{[1,3-dimethyl-7-(3-methylbutyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl]methyl}piperidine-4-carboxamide","bicyclo prostaglandin E2","N-Arachidonoyl-3-hydroxy-|A-aminobutyric acid","trichostatin A","3,3',5,5'-Tetra-tert-butyl-4,4'-dibenzoquinone","Nefazodone","(2R)-2-[[(2R)-2,6-diaminohexanoyl]amino]-3-phenylpropanoic acid","ethyl malonate","3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione","Caffeoylferuloylspermidine","Brivanib","N-Benzoyl-phe-ala-pro","Hydroxyacetone","Masoprocol","N-(7-chloroquinolin-4-yl)-N',N'-diethylethane-1,2-diamine","4-butyl-N-(quinolin-3-yl)benzamide","[(1S,2S,5S,6S,7S)-5-hydroxy-5-(hydroxymethyl)-10-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-3,8-dioxatricyclo[4.4.0.02,4]dec-9-en-7-yl] 3-methylbutanoate","Cyclo(seryltyrosyl)","Casegravol isovalerate","Lewis A trisaccharide","Diethyl 2-((4-hydroxyanilino)methylidene)malonate","(2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-5-Hydroxy-6-(hydroxymethyl)-2-[[(1S,2S,7S,10R,11S,14S,15R,16S,17S,20S,23S)-10,14,16,20-tetramethyl-22-azahexacyclo[12.10.0.02,11.05,10.015,23.017,22]tetracos-4-en-7-yl]oxy]-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol","coniferyl alcohol 9-methyl ether","9-methoxy-2,8-bis(3-methylbut-2-enyl)-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromene-1,3-diol","Acylcarnitine C10:3,COOH","Modrefen","Polyethylene, oxidized","(3S,4aR,6S,8aR)-6-[(4-carboxyphenyl)methyl]-decahydroisoquinoline-3-carboxylic acid","Parapropamol","Moexipril","5-(3-Methyl-5-pentylfuran-2-yl)pentanoylcarnitine","Val-Asp","Corticosterone acetate","7-[2-(furan-3-yl)ethyl]-5-hydroxy-7,8-dimethyl-5,6,6a,8,9,10-hexahydro-1H-benzo[d][2]benzofuran-3-one","1H-Indole-2-carboxylic acid, 1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydro-, (2S,3aR,7aS)-","Canavalioside","5-Oxo-1-propyl-2-pyrrolidineacetic Acid","(2R,3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-{[(1S,4S,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}oxan-2-yl]oxy}-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6-(hydroxymethyl)oxane-2,3,4-triol","R-1 Methanandamide Phosphate","Remifentanil Acid","2,6-Dihydroxy-1,1,7-trimethyl-2,9,10,10a-tetrahydrophenanthren-3-one","3'-Methoxy-[6]-Gingerdiol 3,5-diacetate","Galactose 1-phosphate","7-{4,6-Dihydroxy-2-[3-hydroxyocta-1,5-dien-1-yl]oxan-3-yl}hept-5-enoylcarnitine","Isothebaine","Bornyl ferulate","1-(3,5-Dichlorophenyl)piperazine","9-Oxo-10(E),12(E)-octadecadienoic acid","Dexamethasone-21-acetate","Itaconic acid","Leu-Leu","7-Sulfocholic acid","3',4'-Dihydroxyacetophenone","2-[(5-Chloro-1,3-benzothiazol-2-yl)sulfanyl]acetic acid","DG(18:4(6Z,9Z,12Z,15Z)/18:1(11Z)/0:0)","sorbitol lactate","2-Phenylquinoline","(2-Methylpropyl)(propyl)amine","7-chloro-6-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid","phosphatidylglycerol (1-palmitoyl, 2-palmitoleoyl)","N-(2,3-Dihydro-1h-Inden-5-Yl)tetrazolo[1,5-B]pyridazin-6-Amine","N-undecanoyl-L-Homoserine lactone","Acpd","Methyl 3-[7-acetyloxy-8-(2-hydroxypropan-2-yl)-11-methoxy-4,5a,9-trimethyl-1-oxo-3,6,7,8,9a,10-hexahydro-[2]benzofuro[5,6-b]chromen-9-yl]propanoate","2-tert-Amylanthraquinone","Platensimycin","2-Hydroxy-3-methylpentanoic acid","Pipernonaline","RCS-8 3-methoxy isomer","(3R,7R,8R,8aS)-3,4'-dihydroxy-7'-(2-hydroxyethyl)-4,4,7,8a-tetramethylspiro[2,3,4a,5,6,7-hexahydro-1H-naphthalene-8,2'-3,8-dihydrofuro[2,3-e]isoindole]-6'-one","5-Nitro-2-(piperidin-1-yl)benzoic acid","Melleolide H","(2R)-[[4-(2,6-di-1-Pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]methyl]-3,4-dihydro-2,5,7,8-tetramethyl-2H-1-benzopyran-6-ol","3-ethyl-2-oxosuccinate","1-Demethyl-4,5-dihydrodiazepam","1H-Indol-2-ol","21-Fluoro-11beta-hydroxypregn-4-ene-3,20-dione","N-(2-Aminoethyl)-1-naphthylacetamide","2,6-Naphthalenedicarboxylic acid","O-Succinylhomoserine","1,3,5-Tris(4-hydroxyphenyl)benzene","(2R)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid","8-Deoxy-11-hydroxy-13-chlorogrosheimin","5,11,17,19-Tetrahydroxy-15-methyl-2-oxapentacyclo[9.8.0.01,3.04,9.012,17]nonadeca-4(9),5,7-triene-10,13-dione","(3aS,4R,9bR)-4-(6-bromo-1,3-benzodioxol-5-yl)-8-propan-2-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline","((((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)(hydroxy)phosphoryl)oxy)methyl pivalate","Dodecanoic acid","rac-methyl (2R,3R)-1-methyl-5-oxo-2-(pyridin-3-yl)pyrrolidine-3-carboxylate, trans","4-[(1R,5R)-4,4,8-Trimethyl-3-oxabicyclo[3.3.1]non-7-EN-2-YL]phenol","2-[2-(4-Hydroxy-3-meyhoxyphenyl)ethyl]tetrahydro-6-(4,5-dihydroxy-3-methoxyphenyl)-2H-pyran-4-ol","N-Acetyl-ala-ala-ala-methylester","6-Ethyl-7-hydroxy-3-phenyl-2-(trifluoromethyl)-4H-1-benzopyran-4-one","Taxiresinol","Leu-Arg","N-(2-Oxo-1-Propyl-1,2,3,4-Tetrahydroquinolin-6-Yl)-1-Phenylmethanesulfonamide","Pipotiazine","4-Methylbenzamide","(S)-2-acetamido-4-methyl-N-((S)-4-methyl-1-oxo-1-(((R)-1-oxohexan-2-yl)amino)pentan-2-yl)pentanamide","Pulcherriminic acid","Deacetylvindoline","DG(20:5(5Z,8Z,11Z,14Z,17Z)/18:2(9Z,12Z)/0:0)","Ethyl 4-methyl-5-(1-methylethoxy)-9H-pyrido(3,4-b)indole-3-carboxylate","(10R,11R,12Z,17Z,19E,21S)-21-hydroxy-11,19-dimethyl-10-propan-2-yl-9,26-dioxa-3,15,28-triazatricyclo[23.2.1.03,7]octacosa-1(27),6,12,17,19,25(28)-hexaene-2,8,14,23-tetrone","Geranyl benzoate","ardeemin FQ","APC","Beveno","(9E)-5-hydroxy-17-(1H-indol-3-ylmethyl)-4-methoxy-7,14,15-trimethyl-13-oxa-18-azatetracyclo[9.8.0.01,16.012,14]nonadec-9-ene-2,19-dione","4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline","Gln-Ile","Farnesyl acetone","4-Hydroxy-6-methyl-2-pyrone","D-Urobilinogen","Glycodehydrocholic acid","Tozasertib","10-Butan-2-yl-1-hydroxy-13-(4-oxoquinazolin-3-yl)-8,11-diazatetracyclo[6.6.1.02,7.011,15]pentadeca-2,4,6-triene-9,12-dione","Methionyl-Phenylalanine","Ketanserin","6-(6-Aminohexanamido)hexanoic acid","Sodium (4-methoxybenzoyloxy)acetate","(2-diethoxyphosphoryl-2-methyl-1-oxido-3,4-dihydropyrrol-1-ium-3-yl)methyl N-[3-[5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanoylamino]propyl]carbamate","Sotuletinib","Ile-Asp","3-hydroxytridecanoyl carnitine","Ala-Val","6-Nitro-2H-benzo[b][1,4]thiazin-3(4H)-one","2-((3-Carboxypropyl)carbamoyl)benzoic acid","2-Methylthioadenosine","2-(Hydroxymethyl)-6-[[3,4,5-trihydroxy-6-(4-prop-2-enylphenoxy)oxan-2-yl]methoxy]oxane-3,4,5-triol","2-[(Biphenyl-4-ylcarbonyl)amino]benzoic acid","9-(2,3-Dihydroxypropoxy)-9-oxononanoic acid","Bisbenzimide","Enalapril","1-O-(15-carboxypentadecyl)-2-O-acetylglycero-3-phosphorylcholine","Glutarylcarnitine (C5:0,COOH)","5-Hydroxyvalproic acid","4-Guanidinobutyric acid","9-Hydroxyjasmesoside","5-Hydroxytryptophan","gamma-Glutamyl-propargylglycine","1-Trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea","Acetic acid 16-benzyl-5,12-dihydroxy-5,7,14-trimethyl-13-methylene-18-oxo-17-aza-tricyclo[9.7.0.01,15]octadeca-3,9-dien-2-yl ester","2-[[2-Amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-hydroxybutanoic acid","1H,3H-Naphtho[1,8-cd]pyran-1-one, 3-hydroxy-","3-Aminophenol","[(2R,7R,9R,10R,11S)-11-acetyloxy-10-hydroxy-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-2-yl]methyl acetate","N-Formylmethionine","Dehydroemetine","(+/-)-Pandamarine","Fumaricine","1-Methylpyrrolidine","Eremopetasitenin C3","[2-(Acetyloxymethyl)-10,11-dihydroxy-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-yl] 3-methylbutanoate","Ethyl 2-amino-1,4-dihydro-4-oxopyrimidine-5-carboxylate","PCTR3","beta-glucuronosyl-2-methyl-4-(3-methyl-1,4-dioxonaphthalen-2-yl)butanoate","11-dehydro-thromboxane B3","Cepharanthine","Presqualene Diphosphate","2-Despiperidyl-2-(5-carboxypentylamine) Repaglinide","1,3-dihydroxy-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one","2-[(5Z)-tetradec-5-en-1-yl]cyclobutan-1-one","2-Methyl-6-[[3,4,5-trihydroxy-6-(4-prop-2-enylphenoxy)oxan-2-yl]methoxy]oxane-3,4,5-triol","Methyl acetyl ricinoleate","N-[4-(benzylamino)-3-cyanoquinolin-2-yl]-4-methoxybenzamide","5-Formiminotetrahydrofolate","H-Tyr-val-OH","Villosinol","Carnequinazoline A","Go 6983","2-[[2-[[2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoic acid","4-Oxoretinal","1,6-Dihydroxy-3,7-dimethoxy-2-(2-hydroxy-3-methyl-3-butenyl)-8-(3-methyl-2-butenyl)-xanthone","Oral-Turinabol","(12Z,15Z)-9,10,11-trihydroxyoctadeca-12,15-dienoic acid","4-(7-Hydroxy-6-methoxy-2,3-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)benzene-1,2-diol","4-Methoxybenzyl glucoside","3-Hydroxy-4'-methyl-2-naphthanilide","5,5,7,12,12,14-Hexamethyl-1,4,8,11-tetrazacyclotetradecane","2,3-Dihydroxy-9,10,11-trimethoxy-5,8,13,13a-tetrahydroxy-6H-dibenzo(a,g)chinolysin","N-Carbamoylphenylalanine","Isopropyl tartaric acid","2-[(2-amino-3-hydroxypropanoyl)amino]-3-(1H-indol-3-yl)propanoic acid","Withaperuvin F","Dl-Phenylalanine","2-({[3-Ethyl-6,9,11,15-tetrahydroxy-3-methyl-10-(methylamino)-7-(propan-2-yl)-2-oxa-5,8-diazabicyclo[10.3.1]hexadeca-1(15),5,8,12(16),13-pentaen-4-yl](hydroxy)methylidene}amino)acetic acid","2-Ethyl butylamine","1-((9E)-10-(3,4-Methylenedioxyphenyl)-9-Decenoyl)Pyrrolidine","4-(Naphthalen-2-ylamino)-4-oxobutanoic acid","Diethylene glycol dimethacrylate","6-[(6,8-Dihydroxy-7-methoxy-3-methyl-1-oxo-3,4-dihydroisochromen-4-yl)oxy]-4,8-dihydroxy-7-methoxy-3-methyl-3,4-dihydroisochromen-1-one","Valeryl-4-hydroxyvalsartan","hexadeca-6,9,12-trienedioylcarnitine","2,6-Dimethylpyridine-4-carboxylic acid","4,4'-Dihydroxy-2',6'-dimethoxychalcone","1-[4-(Acetylamino)phenyl]-5-oxopyrrolidine-3-carboxylic acid","Tetracaine","4-(4,4,10,13,14-pentamethyl-3,7,11,15-tetraoxo-2,5,6,12,16,17-hexahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid","Robalzotan","(E)-3-[4-[(E)-3-[4-(4,5-dihydro-1H-imidazol-2-yl)anilino]-3-oxo-prop-1-enyl]phenyl]-N-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]prop-2-enamide","N-(4-ethylphenyl)-4-fluorobenzenesulfonamide","6-hydroxypinoresinol","3-Phenylpropanoic acid","N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)hydrazinecarbothioamide","2-Amino-3-[4-[2-amino-4-methylsulfanylbutanoyl]oxyphenyl]propanoic acid","Capsicum annuum Fluorescent chlorophyll catabolite","C20 sphinganine","diethyl 1H-pyrazole-3,5-dicarboxylate","1,7-Bis(3,4-dihydroxyphenyl)heptan-3-yl acetate","Ferimzone","1-(9Z,12Z,15Z-octadecatrienoyl)-glycero-3-phosphate","PC(36:6)","Acylcarnitine C9:1,OH","Pyributicarb","prolyl-methionine","Budesonide","Fragransol B","(2,2,3,3-Tetramethylcyclopropyl)-[1-(4,4,4-trifluorobutyl)indol-3-yl]methanone","(9R,10R)-10-hydroxy-9-methoxy-10-(4-methoxyphenyl)-2-methyl-2-(4-methylpent-3-enyl)-7,9-dihydropyrano[2,3-]quinolin-8-one","cyclo(alanyl-leucyl)","Ala-Ile","4,4'-(1-Phenylethylidene)bisphenol","4-(Dimethylamino)phenylalanine","N-(3-hydroxyphenyl)-2-[4-(2-methylpropyl)phenyl]propanamide","Dehydrocholic acid","Barbital","L-phenylalanyl-L-glutamic acid","Heterophyllin","Tyrosylglutamic acid","PC(36:3)","Fluvastatin","12-oxo-10,11-dihydro-20-COOH-LTB4","N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-4-[(3S,5R)-3,5-dimethylpiperazin-1-yl]benzamide","Asparaginyl-Phenylalanine","Tyrosine","3-(3,3-Dimethylbutylamino)-4-[(1-methoxy-1-oxo-3-phenylpropan-2-yl)amino]-4-oxobutanoic acid","Fluorohydrocortisone","2'-Norberbamunine","3-Ureidopropionic acid","3-Amino-3-(4-hydroxyphenyl)propanoic acid","xylo-hex-3-ulono-1,4-lactone","Diethyl phenyl phosphate","3-methoxy[1]benzothieno[2,3-c]quinolin-6(5H)-one","Piperchabamide B","Lys-Ala","Ginnalin B","3-Methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one","Cholyltryptophan","8-Acetoxy-4'-methoxypinoresinol","alpha-Eleostearic acid","5-(4-Methylpiperazin-1-yl)-5-oxopentanoic acid","Phe-Arg","Quercetin 3-(6''-malonyl-glucoside)","(1S,4R)-4-[[(2S,3aS,4S)-4-hydroxy-1-oxo-2-propan-2-yl-3,3a-dihydro-2H-imidazo[1,2-a]indol-4-yl]methyl]-1-methyl-2,4-dihydro-1H-pyrazino[2,1-b]quinazoline-3,6-dione","4-Hydroxyestrone","Homoserine","1-Linoleoyl-2-palmitoyl-3-eicosapentaenoyl-glycerol","Triletide","(2R)-2-[[(2R)-2-amino-4-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid","3-Methoxy-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybenzoic acid","N-Docosahexaenoyl Glycine","Hippuric acid","N-Acetylaspartylglutamate","Uridine 5'-monophosphate (UMP)","Antimycin A3","sorbosone 1,4-lactone","Phe-Asp","(5Z,8Z,11Z,14Z)-N-(4-hydroxy-2-methylphenyl)icosa-5,8,11,14-tetraenamide","Isopyrazam","Phe-Asn","Tauro-gamma-muricholic acid","Glycylalanylprolylmethionylphenylalanylvalinamide","Palmatine [M]","1H-3b,8-(Epoxyethano)cyclopent[a]inden-10-one, 3a,4,5,6,7,7a,8,8a-octahydro-3a,4,7a,8a-tetrahydroxy-2-(2-hydroxy-1-methylethyl)-3,5,8-trimethyl-","Acylcarnitine C14:2,COOH","2,4-Dihydroxy-5-tert-butylbenzophenone","Nebivolol","Vernolic acid","3-(11,12-Dihydroxy-15,19-dotriacontadienyl)-5-methyl-2(5H)-furanone, 9CI","L-Tyrosyl-L-Threonine","3-Hydroxy-cis-5-octenoylcarnitine","(2S,4S)-4-cyclohexyl-1-[2-[(2-methyl-1-propanoyloxypropoxy)-(4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carboxylic acid","N-[3-[(1R)-1-[(2R)-6-hydroxy-4-oxo-2-(2-phenylethyl)-2-propyl-3H-pyran-5-yl]propyl]phenyl]-5-(trifluoromethyl)pyridine-2-sulfonamide","1-(Dimethylcarbamoyl)piperidine-3-carboxylic acid","Cavipetin D","cyclo-(seryl-tyrosyl)","Bis(2-ethylhexyl) phthalate","Ppack","Mangostanol","6',7,7,10',10',13'-Hexamethylspiro[1,8-dihydropyrano[2,3-g]indole-3,11'-3,13-diazatetracyclo[5.5.2.01,9.03,7]tetradecane]-2,9,14'-trione","cis-3-hexenol glucoside","5-(Benzyloxy)tryptamine","20-Trifluoroleukotriene B4","Inosine","Kanzonol O","H-Gly-Pro-Arg-OH","Purine deoxyribonucleoside","(2S)-2-[[(2S)-2-azaniumyl-3-(4-hydroxyphenyl)propanoyl]amino]-3-(1H-indol-3-yl)propanoate","9,13-Epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-10-methoxy-9-methyl-11-(methylamino)-, (9S,10R,11R,13R)-","D-Histidine","Estradiol benzoate","4-Biphenylthiocarboxamide","Diethyl 3-hydroxyphenylphosphonate","Leu-Ile","Ilicicolin H","N-(2-Hydroxypropyl)methacrylamide","LPC(18:2/0:0)","Lucidenic acid K","1-Octadecyl Lysophosphatidic Acid","H-Asp-ala-his-lys-OH","Cyclo-Ile-Pro-diketopiperazine","Ala-Gly","10-Deacetyltaxayunnanine A","(E)-2-(2,4-Hexadiynylidene)-1,6-dioxaspiro[4.5]dec-3-ene","4'-Methoxymucidin","2-[(4-Amino-6-anilino-1,3,5-triazin-2-yl)methoxy]benzaldehyde","Dec-4-enedioylcarnitine","N-Tert-butylphenothiazine-10-carboxamide","Serylproline","1-(Morpholin-4-ylsulfonyl)piperidine-4-carboxylic acid","2,4-difluoro-N-[2-(1H-indol-3-yl)ethyl]benzamide","5-Hydroxymethyl-2-furoic acid","Acylcarnitine C17:0,COOH","N-(1,3-benzodioxol-5-yl)-2-(piperidin-1-yl)acetamide","Methamphetamine","Taxol C","Maltotriose","Tryptophyl-Isoleucine","6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol","(2R,7S,13R,14R,16S,19S,20S)-19-(furan-3-yl)-11-hydroxy-9,9,13,20-tetramethyl-4,8,15,18-tetraoxahexacyclo[11.9.0.02,7.02,10.014,16.014,20]docos-10-ene-5,12,17-trione","Sebacic acid","Ilicicolin A","beta-D-gentiobiosyl crocetin","10-hydroxy-1-(2-methylpropylidene)-4-propan-2-yl-4H-pyrazino[2,1-b]quinazoline-3,6-dione","(22E, 24x)-Ergosta-4,6,8,22-tetraen-3-one","Monascoflavin","1,2-bis(Heptanoylthio)glycerophosphocholine","Remoxipride","9-hydroxynonanoate","N,N'-propane-1,3-diyldipyridine-3-carboxamide","RCS-4 M9 metabolite","eugenyl-O-beta-glucopyranoside","SEP-460","3-(1-methyl-1H-pyrazol-5-yl)propanoic acid","beta-Bixin","(3S)-3-(3,4-dihydroxyphenyl)-8-hydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6R)-3,4,5,6-tetrahydroxyoxan-2-yl]oxymethyl]oxan-2-yl]oxy-3,4-dihydro-2H-naphthalen-1-one","Carinol","(2-Amino-4-phenyl-1,3-thiazol-5-yl)(phenyl)methanone","1-(cystein-S-yl)-N-hydroxy-omega-(methylsulfanyl)nonan-1-imine","7-[2-[3-Hydroxyoct-1-en-1-yl]-5-oxocyclopent-2-en-1-yl]hept-5-enoylcarnitine","Gliocladic Acid","naphthalen-1-yl(1-propyl-1H-indol-3-yl)methanone","PE(18:0/18:2)","Cyprodime","8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-2H-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-one","2-[(2,3-dimethyl-5-nitroimidazol-4-yl)amino]ethanol","2-phenylethyl beta-glucopyranoside","4'-Methoxy-alpha-pyrrolidinopropiophenone","myo-Inositol","Heteroartonin A","Methyl n-acetylanthranilate","3-Hydroxychavicol 1-[rhamnosyl-(1->6)-glucoside]","(5R)-5-[(E,3R)-4,4-difluoro-3-hydroxy-4-phenylbut-1-enyl]-1-[6-(2H-tetrazol-5-yl)hexyl]pyrrolidin-2-one","Guaiacin","[17-(5,6-dimethylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] (Z)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate","Penitrem A","Grandisin","S-[Prop-1-enyl]-cysteine S-oxide","Taurocholic acid 3-sulfate","2-(2-Methoxyphenyl)-1-(1-((1-methyl-2-piperidinyl)methyl)-1H-indol-3-yl)ethanone","Dodecanedioic acid","Thalicpureine","gamma-Glutamyl-beta-phenyl-beta-alanine","1-Methylpseudouridine","Isomaltose","(2S,3R,4R,5R,6R)-2-methyl-6-[[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[2-(4-methylcyclohex-3-en-1-yl)propan-2-yloxy]oxan-2-yl]methoxy]oxane-3,4,5-triol","1-{4-[4-Amino-1-(1-Methylethyl)-1h-Pyrazolo[3,4-D]pyrimidin-3-Yl]phenyl}-3-[3-(Trifluoromethyl)phenyl]urea","4-Quinolone-3-Carboxamide Furan CB2 Agonist","(+)-Xanthoplanine","2-[4-(Dibutylamino)-2-hydroxybenzoyl]benzoic acid","Platyphyllenone","12-Oxo-20-carboxy-leukotriene B4","[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[2-hydroxy-4,4,6,6-tetramethyl-2-(2-methylprop-1-enyl)-3,5-dioxocyclohexyl]oxyoxan-2-yl]methyl 3,4,5-trihydroxybenzoate","6-methoxy-N-(2-propylpyrazol-3-yl)pyridazin-3-amine","Nylidrin","Quinic acid","Vorinostat","6-(Dimethylamino)naphthalene-2-carboxylic acid","5-methoxy-1H-benzo[d]imidazole-2-carboxylic acid","5-OxoETE","N-Decanoylglycine","Lactate","Margrapine B","Armepavine","1-Oxazolo[4,5-b]pyridin-2-yl-6-phenyl-hexan-1-one","(1R,3R,5S,8S,13R,14S)-1-Hydroxy-14-(2-hydroxypropan-2-yl)-13-methyl-4,7,10-trioxapentacyclo[6.4.1.19,12.03,5.05,13]tetradecane-6,11-dione","Sph(t18:0)","Noopept","Dibutyl phthalate","6-Ketoestriol","(2S,3R,4R,5R,6R)-2-methyl-6-[[(2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[(2E,4E)-3-methyl-5-[2,6,6-trimethyl-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxycyclohexen-1-yl]penta-2,4-dienoxy]oxan-2-yl]methoxy]oxane-3,4,5-triol","3-(Cyclohexylamino)-2-hydroxy-1-propanesulfonic acid","20-hydroxy-13-14 epoxy-prefusarin","[[(1S,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]-phenylphosphoryl]benzene","Bogoroside","4-[2-(Trifluoromethyl)phenyl]piperidine","10-Hydroxy-7,9-dimethyl-1,3,4,4a,7,7a-hexahydrobenzo[e]naphthalene-2,8,11-trione","3-Hydroxysebacic acid","ethyl (1S,2R,3S,5S)-3-benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate","Val-Ser","Furmecyclox","Benzotest","Abscisic acid","7b-Hydroxy-3-oxo-5b-cholanoic acid","Malic acid","(2R)-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid","1,1'-(1,8-Dioxo-1,8-octanediyl)bis[glycyl-glycine","13-HoTrE","3-Aminothieno[2,3-b]pyridine-2-carboxylic acid","3-(3,4-Dimethoxybenzamido)-3-(4-fluorophenyl)propanoic acid","Arbutamine","Aeglin","Methanone, (1-(5-chloropentyl)-1H-indol-3-yl)(4-methyl-1-naphthalenyl)-","Enterocin 900","(6aS)-1,2,10-trimethoxy-6-methyl-6-oxido-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-6-ium-9-ol","Glaucamine","(8S,9S,10R,11S,13R,14S,17S)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10-methyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-13-carbaldehyde","Prednisolone Phosphate","5-methoxytryptophan","Aloxistatin","Imiprothrin","Histamine","L-Seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginyl-L-asparagine","Chrodrimanin B","Benzoic acid, 4-(1,3-dimethyl-5-phenoxy-1H-pyrazol-4-yl)methyleneaminooxymethyl-, 1,1-dimethylethyl ester","Narceine imide","Traumatin","Oxypurinol","Altersetin","Chaetoglobosin N","Tryptophylaspartic acid","Tetrahydrocolumbamine","1-[(5,5,8a-Trimethyl-2-methylidene-6-oxo-1,3,4,4a,7,8-hexahydronaphthalen-1-yl)methyl]-5-hydroxy-4-(hydroxymethyl)-7-oxabicyclo[4.1.0]hept-3-en-2-one","p-Toluquinone","6-Methyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile","Glycylphenylalanylphenylalanine","Acylcarnitine C13:1,OH","N-formylmethionyl-leucyl-phenylalanyl-lysine","2-(2,6-Dimethylmorpholin-4-yl)-6-(3-methylpiperidin-1-yl)-5-nitropyrimidin-4-amine","Chaetoglobosin A","6',7'-Dihydroxybergamottin","17-Dihydroexemestane","2,3,9,10,11,12-Hexahydro-10S-hydroxy-9-methyl-1-oxo-9R,12S-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, hexyl ester","(E)-Piperolein A","4-Oxohexanoic acid","2-[(2-acetamido-3-phenylpropanoyl)amino]-3-methylbutanoic acid","Pomiferin","Pyrrolidine","Cratoxyarborenone E","7-O-(Triethylsilyl)-10-deacetyl Baccatin III","Denudatin B","Nicotinate","(2S)-2-[[(2R)-2-amino-3-methylbutanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid","[8-[2-[Acetyl(methyl)amino]ethyl]-3,6-dimethoxyphenanthren-4-yl] acetate","(8~{R},9~{S},13~{S},14~{S},16~{E})-13-methyl-3-oxidanyl-16-(phenylmethylidene)-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-17-one","Actinonin","3-Oxocyclobutane-1-carboxylic acid","Laprafylline","1-18:2-2-18:3-phosphatidate","Abyssinone V 4'-methyl ether","S-(2-methylpropanoyl)-dihydrolipoamide","4,4,4-Trifluorobutanoic acid","Dihydroethidium","Taraxacolide 1-O-b-D-glucopyranoside","Phe-Ala","N-Demethyldiltiazem","Advantame","4-Chloro-N-phenylpicolinamide","N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]-N-nitrosoacetamide","Arbaprostil"],"additional_accession":[]},"is_claimable":false,"name":"13(S)-HODE Generated by Rhizopus microsporus var. rhizopodiformis Aggravates MASLD via the Elane-PAR2-SREBP-1c Axis","description":"Abstract Objective:Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) poses a major public health challenge. Increasing data suggest a role of gut fungi in liver disease, yet their diversity and biological function in MASLD are still poorly understood. Methods:Internal transcribed spacer (ITS) sequencing was conducted on fecal samples from 107 individuals with MASLD and 120 matched healthy controls (HC). A high-fat diet (HFD)-induced MASLD mouse model was established, and multi-omics analyses, including liver transcriptomic sequencing, qPCR, WB, and immunofluorescence, were performed to elucidate the molecular mechanisms underlying key gut fungi associated with MASLD. Microbial-derived metabolites involved in MASLD were investigated through multi-omics analyses in vitro and in vivo. Results:MASLD patients showed significantly reduced fungal diversity and richness compared with HC. The gut mycobiota of MASLD patients exhibited a marked increase in the pathogenic genus Rhizopus, particularly Rhizopus microsporus var. rhizopodiformis and R. microsporus var. chinensis, which were positively associated with hepatic steatosis and body mass index (BMI). Fecal microbiota transplantation from MASLD patients into antibiotic-treated mice induced MASLD-like phenotypes, while amphotericin B treatment mitigated disease progression. Oral administration of R. microsporus var. rhizopodiformis in HFD-fed mice aggravated gut dysbiosis, disrupted intestinal barrier integrity, and activated hepatic SREBP-1c signaling, leading to upregulation of key lipogenic enzymes ACC1 and FASN. These changes were mediated through a pro-inflammatory cascade involving the hepatic LPS–TLR4–NF-κB axis and enhanced neutrophil degranulation. 13(S)-HODE, potentially identified as a key metabolite produced by R. microsporus var. rhizopodiformis, aggravated MASLD. 13(S)-HODE promotes neutrophil trafficking to the liver, where released elastase (Elane) directly cleaves and activates the master transcription factor SREBP-1c via a non-canonical PAR2 signaling pathway, leading to uncontrolled hepatic de novo lipogenesis. Conclusion:Our findings suggest that Rhizopus microsporus var. rhizopodiformis and its candidate metabolite 13(S)-HODE are associated with MASLD progression, potentially via the Elane-PAR2-SREBP-1c axis. These observations provide a preliminary basis for further investigating the role of gut fungi in MASLD pathogenesis.","dates":{"publication":"2026-09-22","submission":"2026-09-22"},"accession":"MTBLS15760","cross_references":{}}