NODETranscriptomicsWenyun GuoRNA-Seqhttps://www.biosino.org/node/experiment/detail/OEX00024511Illumina HiSeq 2500SingleRANDOM1['hcc']['Mouse Mosavirus']For diethylnitrosamine (DEN)-CCL4 mouse model establishment, male mice (Kdm6a flox/Y) were administered a single injection (i.p.) of 25 mg/kg DEN at 14 d of age. Thereafter , mice were administered 100 µl CCl4 (25%) i.p. one time per week for up to 12 weeks,17 starting at 8 weeks of age. Mice were then sacrificed, and livers and sera were collected for subsequent analysis.We subjected HCC tumor tissue to RNA-seq.NODEfalseOEX_Wenyun_2307281325Mice with conditional (floxed) alleles of KDM6A were generated by the company (Shanghai Model Organisms Center, Inc.). Genotypes of interest in this study were KDM6Aflox/Y Alb-Cre+; KDM6A flox/YAlb-Cre-. We only subjected HCC tumor tissue to RNA-seq.2023-08-022023-07-28OEX00024511OEP00004319