NODEOtherZiyun LiWGSIllumina HiSeq 2000https://www.biosino.org/node/experiment/detail/OEX00027843PairedRANDOMN1['fecal']['mouse metagenome']Firstly, sixteen male BALB/c mice weighing 14–18 g were purchased from Pengyue Experimental Animal Breeding Co., Ltd. (Jinan, China) and kept under a 12h light/12h dark cycle in standard specific-pathogen-free (SPF) individually vented cages. The mice were given a common diet and free access to water. Mice aged 3 weeks were randomly divided into experimental groups of eight mice, as follows: Control group (gavage with physiological saline (0.9 % NaCl) (150 µL) for 12 days and intraperitoneal injection with physiological saline (0.9 % NaCl) on the 13th day) (Fig.1a); B. infantis group (gavage with 109 CFU/mL B. infantis 15697 (150 µL) for 12 days and intraperitoneal injected physiological saline (0.9 % NaCl) in 13th days) (Fig.1a). After 4 h of intraperitoneal injection, mice were anesthetized and cervical dislocated. Samples (e.g. liver tissue, ileum tissue, ileum chyme, and feces) were taken, and stored in 4 % paraformaldehyde and liquid nitrogen respectively.NODEfalseOEX_Ziyun_2405131055AMRBABIHere, we treated seven mice with Bifidobacterium infantis by gavage for 13 days, while eight mice were set up as a control group to observe the effects of B. infantis supplementation on the fecal metagenomics of mice.2024-05-132024-05-13OEX00027843OEP00005300