ENA0000GenomicsMultiomicsKorea Universityhttps://www.ebi.ac.uk/ena/browser/view/PRJNA102877Bos taurusTo identify transcriptional markers for beef traits related to meat tenderness and moisture, we measured the transcriptome of the Longissimus dorsi skeletal muscle in 10 Korean native cattle (KNC). We analyzed the correlation between the beef transcriptome and measurements of four different beef traits, shear force (SF), water holding capacity (WHC), cooking loss (CL), and loin eye area (LEA). We obtained non-overlapping and unique panels of genes showing strong correlations (|r| > 0.8) with SF, WHC, CL, and LEA, respectively. Functional studies of these genes indicated that SF was mainly related to energy metabolism, and LEA to rRNA processing. Interestingly, our data suggested that WHC is influenced by protein metabolism. Overall, the skeletal muscle transcriptome pointed to the importance of energy and protein metabolism in determining meat quality after the aging process. The panels of transcripts for beef traits may be useful for predicting meat tenderness and moisture. Overall design: Gene expression profiles were correlated with beef traits measured at the same cattle.ENATaurine, dairy cow, Beef Cows, musculus longissimus thoracis, cow, Taurus Cattles, Bos indicus Cattles, Holstein Cow, Taurus Cattle, Cattle, Taurine Cattles, Indicine, Bos indicus, Dairy Cows, Domestic Cows., musculus longissimus dorsi, Bos grunniens, cattle, Bos taurus, Bos primigenius taurus, domestic cattle, Indicine Cattles, Yaks, Holstein, longissimus dorsi muscle, Cattles, longissimus thoracis, Yak, Cows, Domestic Cow, Dairy Cow, longissimus dorsi, Bos bovis, Domestic, Dairy, Taurine Cattle, Beef, Bos Tauurus, Beef Cow, oxen, ox, Cow, Taurus, Indicine Cattle, Zebu, domestic cow, Zebus, Bos indicus Cattle, bovineBos bovis, dairy cow, Bos Tauurus, domestic cattle, domestic cow, oxen, Bos primigenius taurus., bovine, ox, cattle, cow0.00.00.00.00.00falseBos taurusTranscriptomes from Longissimus dorsi samples of Korean Native Cattle (Hanwoo)2022-07-162014-02-11PRJNA102877GSE9256184434169913