ENA0000GenomicsHarvard, Brigham and Women's Hospitalhttps://www.ebi.ac.uk/ena/browser/view/PRJNA415811Mus musculusThe aim of the study was to gain mechanistic insights of the protective effect of forskolin on thapsigargin-induced podocyte death by assessing, analyzing and comparing the respective gene expression profiles. Overall design: Gene expression profiles of vehicle (DMSO)-, thapsi-, and thapsi+fors-treated podocytes were analyzed. 3 replicates per condition. Vehicle (DMSO)-treated cells were served as control/reference samples.ENA6beta, Coleonolk., 9-trimethyl-8-[(2-methyl-1-oxo-2-butenyl)oxy]-2-oxo-4-(1-oxobutoxy)-azuleno[4, data, 3aR, 9b-decahydro-3, colforsinum, 10b-trihydroxy-3, 5-b]furan-7-yl octanoate, 3a, 7beta, thapsigargine, Tg, 10bS)-3-ethenyl-6, 5-b]furan-7-yl ester, 10S, 13-epoxy-1alpha, Glomerular Visceral, 8S, 9alpha-trihydroxylabd-14-en-11-one, 4S, 10, 8alpha(Z), 9b-decahydroazuleno[4, Glomerular, (3R, (3S, 4a, 3, 4, 5, 6, 7, Forskolin, 8, 3a-dihydroxy-3, octanoic acid {3S-[3alpha, 9bS)-6-(acetyloxy)-4-(butanoyloxy)-3, 5S, Colforsin, 4aR, 6aR, 6aS, Coleonol, Thapsigargin, 10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-5-yl acetate, Visceral Epithelial Cells, 9-trimethyl-8-{[(2Z)-2-methylbut-2-enoyl]oxy}-2-oxo-2, FORSKOLIN, 6S, colforsina, 9balpha]}-6-(acetoxy)-2, colforsine, 10aR, Epithelial Cells, 6a, Glomerular Visceral Epithelial Cells, 7beta-acetoxy-8, 4alpha, Podocyte, 6abeta, 3abeta, colforsin, 7S6beta, Coleonolk., 9-trimethyl-8-[(2-methyl-1-oxo-2-butenyl)oxy]-2-oxo-4-(1-oxobutoxy)-azuleno[4, data, 3aR, 9b-decahydro-3, colforsinum, 10b-trihydroxy-3, 5-b]furan-7-yl octanoate, 3a, 7beta, thapsigargine, Tg, 10bS)-3-ethenyl-6, 5-b]furan-7-yl ester, 10S, 13-epoxy-1alpha, Glomerular Visceral, 8S, 9alpha-trihydroxylabd-14-en-11-one, 4S, 10, 8alpha(Z), 9b-decahydroazuleno[4, Glomerular, (3R, (3S, 4a, 3, 4, 5, 6, 7, Forskolin, 8, 3a-dihydroxy-3, octanoic acid {3S-[3alpha, 9bS)-6-(acetyloxy)-4-(butanoyloxy)-3, 5S, Colforsin, 4aR, 6aR, 6aS, Coleonol, Thapsigargin, 10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-5-yl acetate, Visceral Epithelial Cells, 9-trimethyl-8-{[(2Z)-2-methylbut-2-enoyl]oxy}-2-oxo-2, FORSKOLIN, 6S, colforsina, 9balpha]}-6-(acetoxy)-2, colforsine, 10aR, Epithelial Cells, 6a, Glomerular Visceral Epithelial Cells, 7beta-acetoxy-8, 4alpha, Podocyte, 6abeta, 3abeta, colforsin, 7S00.00.00.00.00.0falseExpression data from podocytes cultured in vitro treated with thapsigargin +/- forskolinExpression data from podocytes cultured in vitro treated with thapsigargin +/- forskolin2022-05-122017-10-27PRJNA415811GSE1061722924969510090