{"database":"panorama","file_versions":[],"scores":null,"additional":{"omics_type":["Proteomics"],"submitter":["Wendy Heywood"],"species":["Homo Sapiens"],"full_dataset_link":["https://panoramaweb.org/SARCOV2immunocomplex.url"],"submitter_email":["wendy.heywood@ucl.ac.uk"],"submitter_affiliation":["Translational Mass Spectrometry Research Group, UCL"],"sample_protocol":[""],"repository":["PanoramaPublic"],"data_protocol":[""],"name_synonyms":["mtSerRS, SerRS, liquid chromatography tandem mass spectroscopy, LC-MS2, SerRSmt, LCMSMS, SARS coronavirus caused disease or disorder, SARS coronavirus infectious disease, severe acute respiratory syndrome, LC-MS/MS, SARS-CoV infection, SARS-associated coronavirus, SARS ASSOC CORONAVIRUS, Sars1, SARS coronavirus disease or disorder, Strs, serRS, LC/MS/MS, Acute, acute respiratory coronavirus infection, SARS, liquid chromatography-tandem mass spectroscopy, SYS, SARSM, LC-MSMS, Severe acute respiratory syndrome (disorder), liquid chromatography tandem mass spectrometry, SERRS, LC-MS-MS., SERS, Respiratory Syndrome, Severe, Severe Acute"],"description_synonyms":["liquid chromatography tandem mass spectroscopy, single-organism developmental process, determination, P62, postnatal development, Infestations and Infections, Gene, SARS-CoV infection, growth and development, protein, Immunizations, sci, Complement Protein, SARS ASSOC CORONAVIRUS, protein-containing complex, LC-MS-MS, Active Immunization, serRS, SARS, LC-MSMS, Gene Products, HOW, How, SERRS, SERS, protein aggregate, l(3)j5D5, SerRS, 24B, LCMSMS, l(3)s2612, SARS coronavirus infectious disease, stru, l(3)S053606, CG10293, Sars1, SARS coronavirus disease or disorder, l(3)j5B5, Infestation and Infection, scientific observation, DmelCG10293, Hemolytic, Infections and Infestations, Respiratory Syndrome, Vaccinations, LC-MS2, mtSerRS, measuring, SerRSmt, 0904/17, SARS coronavirus caused disease or disorder, protein complex, clone 2.39, Proteins, LC-MS/MS, SARS-associated coronavirus, qkr, antibodies, l(3)S090417, development, Immunization, active immunization, LC/MS/MS, Strs, native protein, SZ1, SYS, KH93F, chemical analysis, Protein, SARSM, Severe acute respiratory syndrome (disorder), Infection, Active, Hemolytic Complement, clinical infection., Severe Acute, who, Complement, severe acute respiratory syndrome, postnatal growth, Infection and Infestation, Who/How, Active Immunizations, Protein Gene Products, Gene Proteins, Complement Proteins, Acute, acute respiratory coronavirus infection, liquid chromatography-tandem mass spectroscopy, Complement System, qkr[93F], liquid chromatography tandem mass spectrometry, anon-EST:Liang-2.39, assay, growth, Severe"],"additional_accession":[]},"is_claimable":false,"name":"SARS-CoV2 Immunocomplex by LC-MS/MS on vaccinated cohort","description":"We describe the development of a highly specific, mulitplexed targeted proteomic LC-MS/MS assay for accurate quantitation of immunoprotective-proteins  (including several classes of antibodies and complement) to SARS CoV2 S1 spike protein. We demonstrate how antibodies/complement levels can be monitored in response to vaccination with or without previous infection and show their altered level of protection against variants of concern.","dates":{"publication":"Thu Jul 14 00:00:00 BST 2022"},"accession":"PXD028450","cross_references":{"TAXONOMY":["9606"]}}