{"database":"PAXDB","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["http://pax-db.org/downloads/latest/datasets/bioprojects-abundance-files-v4.0.zip"]},"type":"primary"},"statusCodeValue":200,"statusCode":"OK"}],"scores":{"citationCount":0,"reanalysisCount":0,"viewCount":0,"searchCount":0},"additional":{"omics_type":["Proteomics"],"submitter":["Christian von Mering"],"species":["257313"],"full_dataset_link":["https://pax-db.org/dataset/257313/295479343"],"submitter_email":["mering@imls.uzh.ch"],"submitter_affiliation":["University of Zurich"],"sample_protocol":[""],"repository":["PAXDB"],"data_protocol":["For the rescaling, the\ndatasets are first parsed or processed such that the data reflect\nproportional abundances of whole protein molecules\n(i.e. proportionality to counts of complete, individual protein\nmolecules, not to molecular weights, protein volumes, or digested\npeptides). In the case of spectral counting data protein. The proportional abundances are rescaled linearly to add up\nto one million; this means the abundance of each protein of\ninterest is finally expressed in (parts per million,) relative to\nall other proteins in a sample. \nFor a given protein abundance dataset, we then compute\nthe absolute log abundance ratios of all pairs of proteins\nannotated to be functionally linked. The median of these absolute\nlog abundance ratios represents an indirect quality\nmetric: the closer it is to zero, the better (i.e. the more there\nis consistency between abundance values and functional annotations\nsuch as protein complexes or pathways). We then\ncompute a background expectation for this metric, by permuting\nthe abundance values in a given dataset randomly,\nand recomputing the median log abundance ratios. The permutation\nis repeated several times, yielding a distribution of\nmedians. The actually observed median is then expressed as a\nZ-score distance to the random distribution ofmedians—this\ndistance is termed the interaction consistency score."],"pubmed_abstract":["Previous studies have shown that B. pertussis survives inside human macrophages in non-acidic compartments with characteristics of early endosomes. In order to gain new insight into the biology of B. pertussis survival in host cells, we have analyzed the adaptation of the bacterial proteome during intracellular infection. The proteome of B. pertussis 3 h and 48 h after infection of human macrophage-like THP-1 cells was examined by nano-liquid chromatography combined with tandem MS and compared to the protein profile of extracellular B. pertussis growing in the same cell culture medium. Compared with extracellular bacteria, almost 300 proteins out of 762 identified proteins displayed altered levels in intracellular B. pertussis. Functional analyses of the proteins displaying altered abundance revealed enrichment of proteins involved in stress response, iron uptake, cellular metabolism, transcriptional regulation, and virulence. To our knowledge, this is the first analysis of the B. pertussis proteome during adaptation to the intramacrophage environment and the data provide new clues for understanding B. pertussis adaptation and pathogenesis.<h4>Biological significance</h4>B. pertussis is a respiratory pathogen that has adapted exclusively to the human host. Despite high vaccination rates, whooping cough remains a serious threat to human health and its incidence has been increasing in recent years in vaccinated populations. The mechanisms that allow this pathogen to evade immune clearance, persist in the host, and cause a prolonged paroxysmal cough are still poorly understood. Recent studies regarding B. pertussis survival inside host cells and the cellular response to this bacterial infection indicate that B. pertussis may have an intracellular phase during infection which probably contributes to persistence and vaccine failure. In this study we provide the first global proteome profile of B. pertussis within macrophages. The data provide novel insights into the adaptive responses elicited by these bacteria for physiological adaptation to the host environment."],"pubmed_title":["Proteome analysis of Bordetella pertussis isolated from human macrophages."],"pubmed_authors":["Lamberti Yanina Y, Cafiero Juan Hilario JH, Surmann Kristin K, Valdez Hugo H, Holubova Jana J, Večerek Branislav B, Sebo Peter P, Schmidt Frank F, Völker Uwe U, Rodriguez Maria Eugenia ME"],"data_synonyms":["Add, DmelCG43443, ADD, ADD-87, Hts-RC, data, AU023367, Data Set, protein complex, supply, Proteins, Ovhts, Gene, HtsRC, CG9325, protein, neutral molecular compounds, protein-containing complex, Dmel_CG9325, Xt, Peptide, 1B1, add, Polypeptides, anon-EST:Posey9, protein polypeptide chains, native protein, peptido, htsRC, GLI3-190, natural protein, polypeptide chain, Add-hts, Protein, CG43443, Gene Products, l(2)k14523, Dmel_CG34197, l(2)00634, median, Ovhts-RC, background, supply and distribution, protein aggregate, all_pairs, molecule, Bph, molecula, Random selection by shearing, oligonucleotide random primer, proportion, HTS-R1, HTS, Hts, molecules, peptides, l(2)k06121, adducin, GLI3FL, distribution, AI854843, proportionality, add-like, HTS-RC, rate, proteins, Molekuel, Pdn, sample population, introduction, Protein Gene Products, Gene Proteins, Adducin, RANDOM, 10^[-6], ppm, sample, supply., quotient, Peptid, peptidos, Polypeptide, Attention Deficit Hyperactivity Disorder, l(2)01103, EST D, CG34197, HtsF, ratio"],"description_synonyms":["DmelCG5125, Nina C, DRONINAC., NinaC, ninac, Dm NinaC, CT42491, NINA C, CG5125, 2.2, NINAC, CT16120, CG54125, CG 5125"],"pubmed_title_synonyms":["Haemophilus pertussis, human being, Bacterium tussis-convulsivae, Man (Taxonomy), determination, Monocyte Derived Macrophages, Macrophages, Modern, total expressed protein, Bone Marrow Derived Macrophages, Bone Marrow-Derived Macrophage, Monocyte Derived, man, human, Human, Bone Marrow-Derived, Monocyte-Derived Macrophage., Monocyte-Derived, Homo sapiens, Modern Man, chemical analysis, Bone Marrow-Derived Macrophages, assay, Hemophilus pertussis, Proteomes, Man, Monocyte-Derived Macrophages, Microbe de la coqueluche, Macrophage"],"name_synonyms":["Koerper., organism, whole body, multi-cellular organism, whole organism, animal, body"],"pubmed_abstract_synonyms":["host organism, nucleocytoplasm, determination, Incidences, Feature, positive regulation by symbiont of host non-apoptotic programmed cell death, Infestations and Infections, Person-time Rates, Pertusses, Proportion, protein, Environmental., infectivity, Social Controls, Active Immunization, protein polypeptide chains, Readability, macrophage, responsivity, Monocyte-Derived Macrophage, pathogenesis, Impacts, 26Fe, Incidence Rate, Environmental Impacts, protein aggregate, Fs(3)Hor, Formal Social Controls, average, viral infection, modification by symbiont of host biological process, DmelCG2684, Eubacteria, Man (Taxonomy), stimulation by symbiont of host programmed cell death, proteins, NTef2, Bacteria Woese et al. 2024, Social, Environmental Impact, Bacteria <bacteria>, Respiratory, Prokaryotae, intermediary metabolism, Infections and Infestations, Procaryotae, intracellular, functional failure, typical plasmatocyte, Modern, frequency, Pertussis, Liquid Chromatography, Normalcy, infections, monocyte-derived macrophage, Fs(3)Sz11, Immunization, active immunization, Incidence Rates, Iron 56, Pathogenicity, modulation by symbiont of host system process, prokaryotes, Individual, failure, internal to cell, Person-time Rate, Monocyte-Derived Macrophages, Culture Technique, Epistemology, death rate, Iron, MS/MS, Bacterial Diseases, Control, bacterial, Infection and Infestation, Controls, Features, surveillance, induction by organism of programmed cell death in other organism during symbiotic interaction, morbidity, human, Coughing, early, modification by symbiont of host morphology or physiology, Fe, Cell Line, Eisen, Health, Horka, activation by symbiont of host programmed cell death, Cells, CG2684, Fs(3)Horka, Cell Cultures, histiocyte, Secondary Attack Rates, iron, Regulation, Proteomes, Prokaryota, Regulations, Bacterial Disease, human being, Monocyte Derived Macrophages, THP-1 Cell, regulation by symbiont of host system process, Coughs, Gene, Bordetella pertussis Infection, eubacteria, Immunizations, disfunctional, protein-containing complex, Normalcies, Human, Secondary Attack Rate, Rate, Homo sapiens, polypeptide chain, induction by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction, Gene Products, DmF2, THP-1 Cell Lines, Bacteriobiota, Attack Rates, Cell Culture, agranular plasmatocyte, Man, lod, protoplasm, Normalities, THP-1 Cell Line, reactivity, study, induction of non-apoptotic programmed cell death by other organism, hierro, Bacterial Infection, protoplast, Infections, Whooping, occurrence, Receptosome, MS2, prevalence, infection due to Bordetella pertussis, Bone Marrow-Derived Macrophage, causes, man, clinical infection, Monera, Cell Culture Technique, Bone Marrow-Derived, Bacteria (ex Cavalier-Smith 1987), Cumulative, Infestation and Infection, lamellocyte, time of survival, Person-time, causality, Person time Rate, THP 1 Cell Line, Characteristics, fungi, Incidence Proportions, THP 1 Cells, Vaccinations, incidence, macrophagocyte, Individual Health, bacteria, data, Culture Techniques, disruption by symbiont of host cell, activation by organism of non-apoptotic programmed cell death in other organism, hemolysin activity, Formal Social Control, protein complex, Attack Rate, Cumulative Incidence, Incidence, Proteins, Cell Lines, fer, total expressed protein, Secondary Attack, Monocyte Derived, defective, Endosome, Cell, Impact, Environmental, Cumulative Incidences, Monocyte-Derived, uptake, Characteristic, survival, native protein, natural protein, Social Control, Protein, chemical analysis, Infection, Active, Receptosomes, outbreaks, tandem MS, Macrophage, THP-1, Bacterial, ferrum, Normality, Macrophages, not Bacteria Haeckel 1894, Bone Marrow Derived Macrophages, Iron-56, Understanding, Active Immunizations, Lds, endemics, Protein Gene Products, Gene Proteins, extracellular, Secondary, Incidence Proportion, Vaccine, prokaryote, Attack, Modern Man, Cough, Bone Marrow-Derived Macrophages, granulocyte, Environments, epidemics, regulation, virulence, assay, response, cellular metabolism"],"citation_count":["0"],"additional_accession":[]},"is_claimable":false,"name":"Bpertussis Tohama I - Whole organism, normalized spectral counts (Lambertietal,jproteomics2016)","description":"abundance based on normalized spectral counts, Interaction consistency score: 2.2, Coverage: 20","dates":{"publication":"2016"},"accession":"295479343","cross_references":{"pubmed":["26873878"],"uniprot":["Q79GE3_BORPE","Q7VVD8_BORPE","Q7VT26_BORPE","RL5_BORPE","EFTU_BORPE","Q7VY14_BORPE","MNME_BORPE","HIS4_BORPE","Q7VSG0_BORPE","Q7VT13_BORPE","Q7VS70_BORPE","Q7VWW9_BORPE","GLYA_BORPE","Q7VWF6_BORPE","SYR_BORPE","Q7VS35_BORPE","Q7U364_BORPE","Q7VWJ6_BORPE","Q7VT00_BORPE","COAD_BORPE","HTPG_BORPE","BAMB_BORPE","RL24_BORPE","DCUP_BORPE","EX7S_BORPE","Q7VTF6_BORPE","Q7VU04_BORPE","Q7W0K3_BORPE","PNP_BORPE","Q7VYK5_BORPE","Q7VVJ2_BORPE","Q7VZ45_BORPE","Q7VTG4_BORPE","Q7VXZ5_BORPE","PTLF_BORPE","Q7VVD3_BORPE","ARGD2_BORPE","Q7VU92_BORPE","Q7VUP4_BORPE","Q7VTE3_BORPE","Q7VSW7_BORPE","ATPF_BORPE","Q7VZJ6_BORPE","Q7VXB3_BORPE","FIMC_BORPE","RL18_BORPE","RL11_BORPE","Q7VZG2_BORPE","LEUD2_BORPE","Q7VZC9_BORPE","RECA_BORPE","Q7VW66_BORPE","MASZ_BORPE","Q7VVU6_BORPE","UPP_BORPE","ENO_BORPE","HPRK_BORPE","SYM_BORPE","ISPH_BORPE","RS9_BORPE","GCH4_BORPE","SYH_BORPE","FUR_BORPE","RS2_BORPE","RL29_BORPE","ARGB_BORPE","Q7VXA2_BORPE","SYA_BORPE","DCD_BORPE","HEM6_BORPE","PROB_BORPE","ACP_BORPE","GLMM_BORPE","ATPA_BORPE","Q7VS83_BORPE","RIMP_BORPE","Q7VUQ7_BORPE","BVGS_BORPE","Q7VTT7_BORPE","Q7W078_BORPE","CYAA_BORPE","Q7VUE7_BORPE","MRAZ_BORPE","Q7W0S8_BORPE","TOX1_BORPE","Q7VW37_BORPE","Q7VVR7_BORPE","BFRD_BORPE","Q7VUT9_BORPE","TOLB_BORPE","Q7VUG6_BORPE","Q7VVD1_BORPE","Q7VSC7_BORPE","SYK_BORPE","Q7VTI5_BORPE","Q7VVA1_BORPE","NUOD_BORPE","Y1550_BORPE","Q7VTF8_BORPE","Q7VTN8_BORPE","RS15_BORPE","Q7VYZ9_BORPE","Q7VUK3_BORPE","Q7VUS3_BORPE","SYY_BORPE","Q7VTT5_BORPE","Q7VUW6_BORPE","Q7VZX2_BORPE","Q7VZ16_BORPE","Q7VS27_BORPE","SYDND_BORPE","Q7VVY4_BORPE","Y3529_BORPE","ORN_BORPE","Q7VWY8_BORPE","Q7VV94_BORPE","Q7VYB0_BORPE","RLMB_BORPE","TPIS_BORPE","Q7VUZ7_BORPE","Q7VS41_BORPE","Q7VVC7_BORPE","Q7VYR0_BORPE","Q7VUG8_BORPE","Q7VYD1_BORPE","Q7VU82_BORPE","GATB_BORPE","Q7VX60_BORPE","Q7W0A9_BORPE","RL7_BORPE","Q7VV70_BORPE","Q7W0G5_BORPE","GCSP_BORPE","SSB_BORPE","Q7VUP1_BORPE","Q7VW69_BORPE","Q7VV08_BORPE","Q7VZ24_BORPE","Q7VYA4_BORPE","EFTS_BORPE","Q7VXD9_BORPE","Q7VXL9_BORPE","Q7VY59_BORPE","Y2767_BORPE","GSHB_BORPE","Q7VYP8_BORPE","Q7VZ18_BORPE","RSMH_BORPE","Q7VW51_BORPE","Q7VSF2_BORPE","Q7VVK5_BORPE","Q7VS29_BORPE","NDK_BORPE","Q7VXN0_BORPE","Q7VW74_BORPE","Q7VU02_BORPE","Q7VVS5_BORPE","Q7VUP2_BORPE","Q7VYH8_BORPE","Q7VZ00_BORPE","Q7VYN5_BORPE","PYRD_BORPE","OTC_BORPE","ARLY_BORPE","SECA_BORPE","Q7VZQ0_BORPE","PSRP_BORPE","Q7VSN6_BORPE","Q7VVG8_BORPE","Q7VY97_BORPE","Q7TTK0_BORPE","HLDD_BORPE","Q7VZ62_BORPE","Q7VY37_BORPE","DER_BORPE","Q7VYQ2_BORPE","Q7VZ22_BORPE","Q7VW30_BORPE","TOX3_BORPE","Q7VT03_BORPE","Q7VXS4_BORPE","Q7VY44_BORPE","Q7VXP1_BORPE","QUEF_BORPE","Q7VWS6_BORPE","Q7VTK7_BORPE","Q7VVS3_BORPE","AROQ_BORPE","MDH_BORPE","Q7VSY3_BORPE","HIS7_BORPE","Q7VWT3_BORPE","FM2_BORPE","METXS_BORPE","Q7VTU1_BORPE","Q7VZU6_BORPE","PANB_BORPE","Q7W0J8_BORPE","Q7W010_BORPE","Q7VU19_BORPE","Q7W0A0_BORPE","Q7VZ68_BORPE","RL27_BORPE","Q7W008_BORPE","Q7VZG0_BORPE","Q7VUV7_BORPE","HIS1_BORPE","Q7W0D8_BORPE","PTLH_BORPE","Q7VT09_BORPE","Q7VSU4_BORPE","Q7VT64_BORPE","Q7VXM9_BORPE","IF3_BORPE","DNLJ_BORPE","Q7VTF3_BORPE","Q7VVX5_BORPE","TOX2_BORPE","Q7VZ67_BORPE","Q7VTU2_BORPE","DNAK_BORPE","Q7VW36_BORPE","Q7VWL8_BORPE","Q7VYD4_BORPE","LPTD_BORPE","Q7VYY7_BORPE","Q7VTV5_BORPE","Q7VV20_BORPE","PANC_BORPE","Q7W0L2_BORPE","GLMU_BORPE","Q7VSN5_BORPE","Q7VTJ3_BORPE","Q7VZP9_BORPE","Q79H47_BORPE","Q7VYT4_BORPE","Q7VV73_BORPE","Q7VVG2_BORPE","Q7VXX6_BORPE","Q7VY56_BORPE","Q7VUM0_BORPE","ILVC_BORPE","Q7VZF7_BORPE","PURA_BORPE","SYT_BORPE","Q7W0G1_BORPE","Q7W0Q5_BORPE","Q7VXC5_BORPE","Q7VYP5_BORPE","RS11_BORPE","CLPP_BORPE","Q7VVC2_BORPE","Q7VYT5_BORPE","Q7VY05_BORPE","HGD_BORPE","RPOZ_BORPE","SAHH_BORPE","Q7VWX5_BORPE","DAPD_BORPE","RPOB_BORPE","Q7W011_BORPE","ACCA_BORPE","DAPA_BORPE","Q7VTV0_BORPE","Q7VZZ7_BORPE","GLMS_BORPE","Q7VUV6_BORPE","Q7VW31_BORPE","Q7VUG0_BORPE","Q7VTK5_BORPE","Q7VU20_BORPE","Q7VUA3_BORPE","Q7VTT8_BORPE","Q7VTE8_BORPE","Q7W0A4_BORPE","DUT_BORPE","IF2_BORPE","PGK_BORPE","SECB_BORPE","RS10_BORPE","Q7VSD4_BORPE","Q7VWM5_BORPE","Q7VZE7_BORPE","Q79GJ5_BORPE","HIS81_BORPE","SURA_BORPE","Q7VVF9_BORPE","Q7VWW8_BORPE","Q7VY98_BORPE","Q7VXD5_BORPE","DNAJ_BORPE","Q7VWC5_BORPE","ASSY_BORPE","Q7VRY1_BORPE","SYFA_BORPE","RS4_BORPE","Q7VUA5_BORPE","Q7VRY2_BORPE","OBG_BORPE","Q79GE1_BORPE","SYP_BORPE","Q7VZ57_BORPE","Q7W0Q1_BORPE","Q7VX44_BORPE","Q79GP1_BORPE","Q7VUL1_BORPE","Q7W0L1_BORPE","Q7VVC0_BORPE","NTPPB_BORPE","RS6_BORPE","Q7VZE9_BORPE","Q7VSE2_BORPE","MURG_BORPE","Q7W0J9_BORPE","THIC_BORPE","Q7VT05_BORPE","Q7VVM3_BORPE","Q79GT7_BORPE","Q7VW86_BORPE","Q7VTA0_BORPE","Q7VWI0_BORPE","Q7VW33_BORPE","GRPE_BORPE","Q7VZQ1_BORPE","Q7VS00_BORPE","Q79GE2_BORPE","Q7VYP1_BORPE","RPOC_BORPE","Q7VTV1_BORPE","RISB_BORPE","Q7W012_BORPE","Q7VVA9_BORPE","Q7VUW1_BORPE","PTLC_BORPE","DSBA_BORPE","Q7VU09_BORPE","SYQ_BORPE","Q7VSE1_BORPE","LEPA_BORPE","Q7VZF3_BORPE","TOX4_BORPE","Q7VSU1_BORPE","RSMA_BORPE","Q7VT04_BORPE","Q7VZE8_BORPE","Q7W0E8_BORPE","ISPG_BORPE","Q7VT06_BORPE","RRF_BORPE","Q7VXJ4_BORPE","Q7VWM9_BORPE","Q7VYL2_BORPE","Q7VY87_BORPE","Q7VVE5_BORPE","CLPB_BORPE","Q7VWG3_BORPE","Q7VVB8_BORPE","Q7VW73_BORPE","Q7VVV3_BORPE","Q7VUY8_BORPE","Q7VX91_BORPE","PROA_BORPE","Q7VXM1_BORPE","RS8_BORPE","THIG_BORPE","GCSH_BORPE","CLPX_BORPE","RDGC_BORPE","Q7VW38_BORPE","Q7VUK2_BORPE","HSLU_BORPE","TATB_BORPE","DXR_BORPE","Q7VYA5_BORPE","EFP_BORPE","FHAE_BORPE","Q7VZ25_BORPE","SYL_BORPE","Q7W0D5_BORPE","Q7VZC3_BORPE","Q7VTM4_BORPE","Q7VTQ4_BORPE","Q7VU64_BORPE","CH10_BORPE","Q7VT54_BORPE","Q7VU69_BORPE","ARGC_BORPE","Q7W0C2_BORPE","RS3_BORPE","Q7VWH1_BORPE","Q7W0C9_BORPE","Y2308_BORPE","Q7VWQ4_BORPE","SYS_BORPE","Q7VUX0_BORPE","Q7VVA0_BORPE","MURD_BORPE","Q7VV21_BORPE","TRMB_BORPE","Q7VUH5_BORPE","AROC_BORPE","ERPA_BORPE","Q7VVZ8_BORPE","RPOA_BORPE","Q79GM4_BORPE","Q7VXZ9_BORPE","Q79GN7_BORPE","Q7VSM5_BORPE","Q7VUQ8_BORPE","Q7VXY1_BORPE","Q7VYW4_BORPE","Q7VZ84_BORPE","Q7VU98_BORPE","Q7VSH9_BORPE","GCST_BORPE","Q7VTE9_BORPE","Q7VY28_BORPE","Q7VYN8_BORPE","Q7VU05_BORPE","MOBA_BORPE","Q7VWY4_BORPE","Q7VUU1_BORPE","ARGD1_BORPE","Q7VXM8_BORPE","Q7VWA4_BORPE","Q7VUA1_BORPE","RL17_BORPE","Q7VS71_BORPE","Q7VXY8_BORPE","ATPG_BORPE","Q7VW65_BORPE","Q7VUN9_BORPE","Q7VSS1_BORPE","Q7VSL9_BORPE","RL4_BORPE","Q7VYZ8_BORPE","Q7VZF0_BORPE","Q7VZB0_BORPE","SUCC_BORPE","RL23_BORPE","Q7VZN7_BORPE","RL10_BORPE","APT_BORPE","Q7VTP8_BORPE","Q7VZH1_BORPE","MNMA_BORPE","NRDR_BORPE","Q7VTG5_BORPE","Q7VVN1_BORPE","Q7VUU6_BORPE","Q7VYW1_BORPE","Q79GE7_BORPE","Q7VSU5_BORPE","Q7VYH9_BORPE","Q7VYP9_BORPE","Q7VUP3_BORPE","GLPK_BORPE","Q7VU53_BORPE","Q7VU00_BORPE","Q7VVC4_BORPE","Q7VTN5_BORPE","FETP_BORPE","BRKA_BORPE","RL19_BORPE","Q7VXM3_BORPE","RL6_BORPE","BVGA_BORPE","RL9_BORPE","CATA_BORPE","Q7VYV3_BORPE","Q7VWG5_BORPE","Q7VWW5_BORPE","Q79GX8_BORPE","Q7VWM2_BORPE","Q7VW67_BORPE","Q7VXH5_BORPE","SYI_BORPE","Q7VZ50_BORPE","SYV_BORPE","Q7VY09_BORPE","Q7VUR4_BORPE","RL25_BORPE","Q7VYP7_BORPE","Q7VZ17_BORPE","Q7VZG6_BORPE","KPRS_BORPE","Q7VV40_BORPE","Q7VXW9_BORPE","Q7VY89_BORPE","Q7VSA2_BORPE","FMT_BORPE","KGUA_BORPE","Q7VY71_BORPE","Q7W080_BORPE","Q7VSV3_BORPE","FOLD1_BORPE","CSPA_BORPE","Q7VZG5_BORPE","Q7VZT6_BORPE","Q7VSK4_BORPE","Q7VRZ4_BORPE","METE_BORPE","Q7VVA2_BORPE","FABH_BORPE","CH60_BORPE","ATPD_BORPE","Q7VZ75_BORPE","Q7VUT2_BORPE","Y690_BORPE","Q7VVC8_BORPE","Q7VVI8_BORPE","Q7VU01_BORPE","Q7VSR6_BORPE","TRPC_BORPE","GPMA_BORPE","RL31B_BORPE","Q7VXZ7_BORPE","Q7VW70_BORPE","Q7VSH0_BORPE","Q7VXG4_BORPE","Q7VT23_BORPE","PUR5_BORPE","FHAC_BORPE","GATA_BORPE","Q7VS25_BORPE","Q7VSN0_BORPE","Q7VX06_BORPE","Q7VXH1_BORPE","Q7W0G6_BORPE","Q7VV05_BORPE","Q7VTY1_BORPE","Q7VZC0_BORPE","Q7VTF9_BORPE","GSA_BORPE","TIG_BORPE","Q7VYQ8_BORPE","Q7VT91_BORPE","Q7VXA4_BORPE","Q7VYC2_BORPE","SODF_BORPE","Q7VS73_BORPE","RL2_BORPE","HISX_BORPE","Q7VY72_BORPE","Q7VYK8_BORPE","Q7W0C0_BORPE","Q7VT29_BORPE","Q7VS26_BORPE","Q7VVJ6_BORPE","Q7VV97_BORPE","RS16_BORPE","Q7VV04_BORPE","Q7VY32_BORPE","MINE_BORPE","AMPA_BORPE","Q79GG1_BORPE","Q7VZ27_BORPE","RL3_BORPE","Q7VY16_BORPE","Q7VU33_BORPE","Q7VXX1_BORPE","ARGJ_BORPE","ILVD1_BORPE","NUOB_BORPE","Q7VVC9_BORPE","Q7VYH5_BORPE","Q7VXK5_BORPE","EFG_BORPE","LPXD_BORPE","RS17_BORPE","RUVB_BORPE","Q7VU86_BORPE","Q7W083_BORPE","Q7VWL2_BORPE","Q7VZ83_BORPE","RL22_BORPE","Q7VX12_BORPE","HISZ_BORPE","Q7VUS9_BORPE","Q7VXW0_BORPE","Q7VW04_BORPE","Q7VVJ1_BORPE","Q7VYB3_BORPE","KDSA_BORPE","Q7VUX9_BORPE","Q7VXA8_BORPE","Q7VW64_BORPE","Q7VSW2_BORPE","Q7VXW3_BORPE","LOLA_BORPE","Q7VU40_BORPE","Q7VTS0_BORPE","PYRH_BORPE","Q7VYQ9_BORPE","Q7VZ29_BORPE","Q7VTM8_BORPE","Q7W0I4_BORPE","Q7VUN3_BORPE","Q7VTG8_BORPE","Q7VZN4_BORPE","Q7VZS4_BORPE","Q7VZ89_BORPE","Q7VYL9_BORPE","Q7VZC4_BORPE","Q7VZC7_BORPE","Q7VT25_BORPE","Q7VSQ5_BORPE","HFQ_BORPE","TRPD_BORPE","OMP_BORPE","RF3_BORPE","Q7VYS1_BORPE","Q7VUT1_BORPE","Q7VYR6_BORPE","Q7VUZ1_BORPE","Q7VSL7_BORPE","Q7VW07_BORPE","NADK_BORPE","Q7VWP7_BORPE","Q7VXM0_BORPE","Q7VYR3_BORPE","Q7VWE5_BORPE","ATPB_BORPE","Q7VVZ2_BORPE","Q7VS81_BORPE","Q7VWA2_BORPE","Q7VVI7_BORPE","Q7VYC1_BORPE","Q7VUH8_BORPE","FHAB_BORPE","Q7VSM1_BORPE","APAG_BORPE","Q7VXP9_BORPE","Q7VWE8_BORPE","Q7VXF6_BORPE","RL15_BORPE","Q7VZ87_BORPE","HEM3_BORPE","KAD_BORPE","Q7VX14_BORPE","LOLB_BORPE","SYE_BORPE","Q7W0S4_BORPE","Q7VZ34_BORPE","Q7VWA1_BORPE","Q7VY26_BORPE","Q7VSA8_BORPE","Q7VSG5_BORPE","Q7VUS8_BORPE","Q7VZB9_BORPE","Q7VT90_BORPE","RL14_BORPE","Q7VY76_BORPE","Q7VXF7_BORPE","Q7VTN0_BORPE","PUR7_BORPE","Q7VUX8_BORPE","Q7VUH9_BORPE","PERT_BORPE","Q7VTM5_BORPE","DHAS_BORPE","METK_BORPE","TRPB_BORPE","RL1_BORPE","Q7VTC2_BORPE","IHFA_BORPE","PLP1_BORPE","Q7VY25_BORPE","GUAA_BORPE","Q7VZC5_BORPE","Q7VYL8_BORPE"]}}