<HashMap><database>PAXDB</database><file_versions><headers><Content-Type>application/xml</Content-Type></headers><body><files><Other>http://pax-db.org/downloads/latest/datasets/bioprojects-abundance-files-v4.0.zip</Other></files><type>primary</type></body><statusCode>OK</statusCode><statusCodeValue>200</statusCodeValue></file_versions><scores><citationCount>0</citationCount><reanalysisCount>0</reanalysisCount><viewCount>0</viewCount><searchCount>0</searchCount></scores><additional><omics_type>Proteomics</omics_type><submitter>Christian von Mering</submitter><species>9606</species><full_dataset_link>https://pax-db.org/dataset/9606/377562898</full_dataset_link><submitter_email>mering@imls.uzh.ch</submitter_email><submitter_affiliation>University of Zurich</submitter_affiliation><sample_protocol></sample_protocol><repository>PAXDB</repository><data_protocol>For the rescaling, the
datasets are first parsed or processed such that the data reflect
proportional abundances of whole protein molecules
(i.e. proportionality to counts of complete, individual protein
molecules, not to molecular weights, protein volumes, or digested
peptides). In the case of spectral counting data protein. The proportional abundances are rescaled linearly to add up
to one million; this means the abundance of each protein of
interest is finally expressed in (parts per million,) relative to
all other proteins in a sample. 
For a given protein abundance dataset, we then compute
the absolute log abundance ratios of all pairs of proteins
annotated to be functionally linked. The median of these absolute
log abundance ratios represents an indirect quality
metric: the closer it is to zero, the better (i.e. the more there
is consistency between abundance values and functional annotations
such as protein complexes or pathways). We then
compute a background expectation for this metric, by permuting
the abundance values in a given dataset randomly,
and recomputing the median log abundance ratios. The permutation
is repeated several times, yielding a distribution of
medians. The actually observed median is then expressed as a
Z-score distance to the random distribution ofmedians—this
distance is termed the interaction consistency score.</data_protocol><data_synonyms>Add, DmelCG43443, ADD, ADD-87, Hts-RC, data, AU023367, Data Set, protein complex, supply, Proteins, Ovhts, Gene, HtsRC, CG9325, protein, neutral molecular compounds, protein-containing complex, Dmel_CG9325, Xt, Peptide, 1B1, add, Polypeptides, anon-EST:Posey9, protein polypeptide chains, native protein, peptido, htsRC, GLI3-190, natural protein, polypeptide chain, Add-hts, Protein, CG43443, Gene Products, l(2)k14523, Dmel_CG34197, l(2)00634, median, Ovhts-RC, background, supply and distribution, protein aggregate, all_pairs, molecule, Bph, molecula, Random selection by shearing, oligonucleotide random primer, proportion, HTS-R1, HTS, Hts, molecules, peptides, l(2)k06121, adducin, GLI3FL, distribution, AI854843, proportionality, add-like, HTS-RC, rate, proteins, Molekuel, Pdn, sample population, introduction, Protein Gene Products, Gene Proteins, Adducin, RANDOM, 10^[-6], ppm, sample, supply., quotient, Peptid, peptidos, Polypeptide, Attention Deficit Hyperactivity Disorder, l(2)01103, EST D, CG34197, HtsF, ratio</data_synonyms><name_synonyms>cortical plate (CTXpl), brain cortex, cortex of cerebral hemisphere, Allocortices, cortical plate (areas), Cortex, Periallocortex, Cortex Cerebrus, Cerebral Cortices, Cortical, Periallocortices, Plate, Paleocortex, Cortical Plates, Archipalliums, pallium of the brain, Allocortex, Cortex Cerebri, cortex cerebri, Cerebral, cortex cerebralis, Archipallium, Paleocortices, Cortical Plate.</name_synonyms><citation_count>0</citation_count></additional><is_claimable>false</is_claimable><name>H.sapiens - Cerebral cortex, SC (Wilhelm,nature,2014)</name><description>abundance based on Spectral counting, Interaction consistency score: 4.5, Coverage: 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ot><uniprot>XRCC6_HUMAN</uniprot><uniprot>QCR1_HUMAN</uniprot><uniprot>CA2D2_HUMAN</uniprot><uniprot>FETUB_HUMAN</uniprot><uniprot>B4E171_HUMAN</uniprot><uniprot>TIM22_HUMAN</uniprot><uniprot>HSPB1_HUMAN</uniprot><uniprot>AAMP_HUMAN</uniprot><uniprot>PSA6_HUMAN</uniprot><uniprot>PGM1_HUMAN</uniprot><uniprot>UB2D2_HUMAN</uniprot><uniprot>ECH1_HUMAN</uniprot><uniprot>PGAM1_HUMAN</uniprot><uniprot>HLAG_HUMAN</uniprot><uniprot>CO4A_HUMAN</uniprot><uniprot>CCD57_HUMAN</uniprot><uniprot>AGRL2_HUMAN</uniprot><uniprot>TEBP_HUMAN</uniprot><uniprot>XRCC5_HUMAN</uniprot><uniprot>APLP2_HUMAN</uniprot><uniprot>E9PLN8_HUMAN</uniprot><uniprot>PGAM4_HUMAN</uniprot><uniprot>CD59_HUMAN</uniprot><uniprot>CREL1_HUMAN</uniprot><uniprot>RUXE_HUMAN</uniprot><uniprot>BGAL_HUMAN</uniprot><uniprot>PAL4D_HUMAN</uniprot><uniprot>LYAG_HUMAN</uniprot><uniprot>CALM1_HUMAN</uniprot><uniprot>PAL4G_HUMAN</uniprot><uniprot>GRB2_HUMAN</uniprot><uniprot>RANG_HUMAN</uniprot><uniprot>ATP4A_HUMAN</uniprot><uniprot>TSPO_HUMAN</uniprot><uniprot>ACON_HUMAN</uniprot><uniprot>PAP1L_HUMAN</uniprot><uniprot>ACE_HUMAN</uniprot><uniprot>KNG1_HUMAN</uniprot><uniprot>PSA7_HUMAN</uniprot><uniprot>S10A4_HUMAN</uniprot><uniprot>H4_HUMAN</uniprot><uniprot>PLA2R_HUMAN</uniprot><uniprot>NCKX3_HUMAN</uniprot><uniprot>GRP75_HUMAN</uniprot><uniprot>PZP_HUMAN</uniprot><uniprot>FSCN1_HUMAN</uniprot><uniprot>GPIX_HUMAN</uniprot><uniprot>B3AT_HUMAN</uniprot><uniprot>KAP2_HUMAN</uniprot><uniprot>THTR_HUMAN</uniprot><uniprot>CA2D1_HUMAN</uniprot><uniprot>TXNL1_HUMAN</uniprot><uniprot>TXD17_HUMAN</uniprot><uniprot>FAAA_HUMAN</uniprot><uniprot>CX6B1_HUMAN</uniprot><uniprot>DRA_HUMAN</uniprot><uniprot>AOXA_HUMAN</uniprot><uniprot>PLGT3_HUMAN</uniprot><uniprot>QSPP_HUMAN</uniprot><uniprot>UB2D4_HUMAN</uniprot><uniprot>NDUBA_HUMAN</uniprot><uniprot>DREB_HUMAN</uniprot><uniprot>EF1G_HUMAN</uniprot><uniprot>JAG1_HUMAN</uniprot><uniprot>CRYAB_HUMAN</uniprot><uniprot>APT_HUMAN</uniprot><uniprot>WIPF1_HUMAN</uniprot><uniprot>SSR2_HUMAN</uniprot><uniprot>CTL2_HUMAN</uniprot><uniprot>ST1A1_HUMAN</uniprot><uniprot>RNZ2_HUMAN</uniprot><uniprot>PGAM2_HUMAN</uniprot><uniprot>BIN1_HUMAN</uniprot><uniprot>NQO2_HUMAN</uniprot><uniprot>SQOR_HUMAN</uniprot><uniprot>HSP13_HUMAN</uniprot><uniprot>GALT2_HUMAN</uniprot><uniprot>KRT84_HUMAN</uniprot><uniprot>KAP0_HUMAN</uniprot><uniprot>PLF4_HUMAN</uniprot><uniprot>FIBG_HUMAN</uniprot><uniprot>DRB5_HUMAN</uniprot><uniprot>CH60_HUMAN</uniprot><uniprot>THOP1_HUMAN</uniprot><uniprot>H2A1J_HUMAN</uniprot><uniprot>F234B_HUMAN</uniprot><uniprot>CTL1_HUMAN</uniprot><uniprot>OGA_HUMAN</uniprot><uniprot>ST1A2_HUMAN</uniprot><uniprot>CLIP1_HUMAN</uniprot><uniprot>MRP_HUMAN</uniprot><TAXONOMY>2184181</TAXONOMY></cross_references></HashMap>