{"database":"ENA","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Fastqsanger.gz":["ftp://ftp.sra.ebi.ac.uk/vol1/fastq/DRR066/DRR066829/DRR066829.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/DRR066/DRR066831/DRR066831.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/DRR066/DRR066830/DRR066830.fastq.gz"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Kazusa DNA Research Institute"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJDB5073"],"scientific_name":["Mus musculus"],"long_description":["Virus infection induces T follicular helper (TFH) and T helper 1 (TH1) cells. Although TFH cells are important in anti-viral humoral immunity, the role of TH 1 cells is still elusive. IgG2 antibodies predominate in the response to vaccination with inactivated Influenza A virus (IAV) and were responsible for protective immunity to lethal challenge with pathogenic H5N1 and pandemic H1N1 IAVs even in mice lacking TFH cells owing to B or T cell-specific ablation of the Bcl6. B cells of wild type (WT) and conditional Bcl6-/- mice were sorted and the transcription of IgG were analyzed by using Illumina MiSeq."],"repository":["ENA"],"additional_accession":[]},"is_claimable":false,"name":"Mus musculus","description":"Next Generation Sequencing Facilitates Quantitative Analysis of IgG transcription in Wild Type and Bcl6-/- B cells","dates":{"last_updated":"2025-09-24","first_public":"2016-10-15"},"accession":"PRJDB5073","cross_references":{"taxon":["10090"]}}