ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR380/004/ERR3804474/ERR3804474_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR380/003/ERR3804473/ERR3804473_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR380/005/ERR3804475/ERR3804475_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR380/000/ERR3804500/ERR3804500_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR380/005/ERR3804475/ERR3804475_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR380/004/ERR3804474/ERR3804474_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR380/000/ERR3804500/ERR3804500_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR380/003/ERR3804473/ERR3804473_1.fastq.gzprimaryOK200GenomicsCARDIFF SCHOOL OF BIOSCIENCEShttps://www.ebi.ac.uk/ena/browser/view/PRJEB32932The propensity of Burkholderia bacteria to develop adaptive resistance to the proprietary preservative ethylzingerone [4-(3-ethoxy-4-hydroxyphenyl) butan-2-one)] was evaluated using Burkholderia vietnamiensis strain G4. The model organism was progressively sub-cultured in increasing concentrations of ethylzingerone starting at up to eight-fold lower than the minimum inhibitory concentration (>0.03125% w/v active). Genomic alterations in three ethylzingerone-adapted derivatives of B.vietnamiensis strain G4 were identified using whole-genome sequencing and analysis with a rapid haploid variant calling and core genome alignment tool (SNIPPY).ENAfalseWhole-genome sequencing of Burkholderia vietnamiensis strain G4 following exposure to sub-lethal concentrations of ethylzingeroneGenomic alterations in Burkholderia vietnamiensis strain G4 exposed to sub-lethal concentrations of ethylzingerone identified by whole-genome sequencing analysis.2019-06-072020-01-11PRJEB32932