ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/000/ERR3379630/ERR3379630_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/005/ERR3379615/ERR3379615_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/001/ERR3379621/ERR3379621_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/000/ERR3379620/ERR3379620_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/008/ERR3379618/ERR3379618_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/009/ERR3379629/ERR3379629_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/007/ERR3379617/ERR3379617_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/008/ERR3379628/ERR3379628_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/006/ERR3379616/ERR3379616_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/009/ERR3379629/ERR3379629_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/000/ERR3379630/ERR3379630_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/006/ERR3379626/ERR3379626_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/005/ERR3379625/ERR3379625_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/007/ERR3379627/ERR3379627_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/005/ERR3379615/ERR3379615_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/002/ERR3379622/ERR3379622_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/001/ERR3379621/ERR3379621_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/003/ERR3379623/ERR3379623_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/004/ERR3379624/ERR3379624_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/000/ERR3379620/ERR3379620_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/008/ERR3379628/ERR3379628_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/007/ERR3379627/ERR3379627_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/009/ERR3379619/ERR3379619_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/004/ERR3379624/ERR3379624_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/006/ERR3379626/ERR3379626_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/009/ERR3379619/ERR3379619_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/005/ERR3379625/ERR3379625_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/008/ERR3379618/ERR3379618_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/002/ERR3379622/ERR3379622_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/006/ERR3379616/ERR3379616_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/007/ERR3379617/ERR3379617_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR337/003/ERR3379623/ERR3379623_2.fastq.gzprimary200OKGenomicsEuropean Bioinformatics InstituteUCLA School of Medicine Division of Hematology and Oncology Center for Iron Disordershttps://www.ebi.ac.uk/ena/browser/view/PRJEB33085ArrayExpressWhole exome sequencing to determine whether acquisition of resistance to MK2206 in MDA-MB-361 is mediated by a new AKT1 mutation. Cells were exposed in vitro to drug for 12 weeks. Surviving cells were expanded for another 2 weeks in the presence of drug before sequencing.ENAfalseMDA-MB-361 breast adenocarcinoma cells treated in vitro with allosteric AKT inhibitor MK2206 until development of resistance.MDA-MB-361 breast adenocarcinoma cells treated in vitro with allosteric AKT inhibitor MK2206 until development of resistance.2023-06-022023-06-02PRJEB33085