ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/005/ERR4190135/ERR4190135_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/007/ERR4190137/ERR4190137_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/003/ERR4190133/ERR4190133_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/006/ERR4190136/ERR4190136_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/001/ERR4190131/ERR4190131_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/000/ERR4190130/ERR4190130_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/004/ERR4190124/ERR4190124_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/003/ERR4190123/ERR4190123_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/002/ERR4190122/ERR4190122_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/005/ERR4190135/ERR4190135_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/006/ERR4190136/ERR4190136_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/004/ERR4190124/ERR4190124_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/001/ERR4190121/ERR4190121_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/007/ERR4190137/ERR4190137_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/005/ERR4190125/ERR4190125_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/000/ERR4190120/ERR4190120_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/007/ERR4190127/ERR4190127_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/008/ERR4190128/ERR4190128_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/006/ERR4190126/ERR4190126_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/003/ERR4190123/ERR4190123_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/002/ERR4190122/ERR4190122_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/003/ERR4190133/ERR4190133_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/009/ERR4190129/ERR4190129_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/001/ERR4190121/ERR4190121_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/001/ERR4190131/ERR4190131_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/000/ERR4190120/ERR4190120_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/000/ERR4190130/ERR4190130_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/005/ERR4190125/ERR4190125_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/006/ERR4190126/ERR4190126_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/009/ERR4190129/ERR4190129_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/007/ERR4190127/ERR4190127_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR419/008/ERR4190128/ERR4190128_1.fastq.gzftp://primaryOK200GenomicsCenter for Spatial and Functional Genomics, Children’s Hospital of Philadelphia, Philadelphia, 19104, PA, USA Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, 19104, PA, USA Divisions of Genetics and Endocrinology, Children’s Hospital of Philadelphia, Philadelphia, 19104, PA, USAEuropean Bioinformatics Institutehttps://www.ebi.ac.uk/ena/browser/view/PRJEB38644ArrayExpressTo connect the neuronal developmental disorders associated GWAS signal to their target effector genes, we performed an integrated analysis of transcriptomics, epigenomics and chromatin conformation changes in an in vitro cellular model. Induced human pluripotent stem cell–derived neural progenitor cells (NPCs) were differentiated into neurons and then subjected to a combination of high-resolution promoter-focused Capture C, ATAC-seq and RNA-seq.ENANerve, Neuron, iPS cell, iPSC, Nerve Cells, Nerve Cell, Nerve., INSDC_feature:regulatory, Cell, CellsNerve, Neuron, iPS cell, iPSC, Nerve Cells, Nerve Cell, Nerve., INSDC_feature:regulatory, Cell, CellsfalsePromoter Capture-C of iPSC-derived NPCs and neuronsPromoter Capture-C of iPSC-derived NPCs and neurons2021-05-272021-05-08PRJEB38644