ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/002/ERR5206932/ERR5206932_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/007/ERR5206917/ERR5206917_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/005/ERR5206905/ERR5206905_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/000/ERR5206920/ERR5206920_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/003/ERR5206883/ERR5206883.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/004/ERR5206934/ERR5206934_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/001/ERR5206901/ERR5206901.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/008/ERR5206878/ERR5206878.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/009/ERR5206919/ERR5206919_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/001/ERR5206871/ERR5206871.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/007/ERR5206927/ERR5206927_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/007/ERR5206897/ERR5206897.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/003/ERR5206913/ERR5206913_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/000/ERR5206890/ERR5206890.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/000/ERR5206910/ERR5206910_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/002/ERR5206922/ERR5206922_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/006/ERR5206926/ERR5206926_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/004/ERR5206914/ERR5206914_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/005/ERR5206885/ERR5206885.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/006/ERR5206866/ERR5206866.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/007/ERR5206907/ERR5206907_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/006/ERR5206876/ERR5206876.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/009/ERR5206929/ERR5206929_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/005/ERR5206925/ERR5206925_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/007/ERR5206937/ERR5206937_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/005/ERR5206895/ERR5206895.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/003/ERR5206903/ERR5206903_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/004/ERR5206904/ERR5206904_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/004/ERR5206914/ERR5206914_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/008/ERR5206918/ERR5206918_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/006/ERR5206886/ERR5206886.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/003/ERR5206923/ERR5206923_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/003/ERR5206933/ERR5206933_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/003/ERR5206893/ERR5206893.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/005/ERR5206935/ERR5206935_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/000/ERR5206910/ERR5206910_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/008/ERR5206868/ERR5206868.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/006/ERR5206916/ERR5206916_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/008/ERR5206908/ERR5206908_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/003/ERR5206923/ERR5206923_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/001/ERR5206881/ERR5206881.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/002/ERR5206932/ERR5206932_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/001/ERR5206891/ERR5206891.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/008/ERR5206888/ERR5206888.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/003/ERR5206913/ERR5206913_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/004/ERR5206904/ERR5206904_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/008/ERR5206898/ERR5206898.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/007/ERR5206907/ERR5206907_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/006/ERR5206936/ERR5206936_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/003/ERR5206873/ERR5206873.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/006/ERR5206926/ERR5206926_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/000/ERR5206900/ERR5206900.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/005/ERR5206915/ERR5206915_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/003/ERR5206903/ERR5206903_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/000/ERR5206870/ERR5206870.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/004/ERR5206934/ERR5206934_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/006/ERR5206896/ERR5206896.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/002/ERR5206922/ERR5206922_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/007/ERR5206877/ERR5206877.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/006/ERR5206936/ERR5206936_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/001/ERR5206911/ERR5206911_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/000/ERR5206930/ERR5206930_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/009/ERR5206929/ERR5206929_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/007/ERR5206917/ERR5206917_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/004/ERR5206884/ERR5206884.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/004/ERR5206894/ERR5206894.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/004/ERR5206924/ERR5206924_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/002/ERR5206912/ERR5206912_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/005/ERR5206875/ERR5206875.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/009/ERR5206909/ERR5206909_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/005/ERR5206905/ERR5206905_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/001/ERR5206931/ERR5206931_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/007/ERR5206927/ERR5206927_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/008/ERR5206908/ERR5206908_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/007/ERR5206867/ERR5206867.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/000/ERR5206920/ERR5206920_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/001/ERR5206931/ERR5206931_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/006/ERR5206916/ERR5206916_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/002/ERR5206892/ERR5206892.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/001/ERR5206921/ERR5206921_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/006/ERR5206906/ERR5206906_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/002/ERR5206902/ERR5206902_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/005/ERR5206935/ERR5206935_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/009/ERR5206899/ERR5206899.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/000/ERR5206880/ERR5206880.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/008/ERR5206918/ERR5206918_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/007/ERR5206937/ERR5206937_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/004/ERR5206874/ERR5206874.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/007/ERR5206887/ERR5206887.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/003/ERR5206933/ERR5206933_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/002/ERR5206912/ERR5206912_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/008/ERR5206928/ERR5206928_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/005/ERR5206915/ERR5206915_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/001/ERR5206911/ERR5206911_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/009/ERR5206879/ERR5206879.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/002/ERR5206872/ERR5206872.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/000/ERR5206930/ERR5206930_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/009/ERR5206869/ERR5206869.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/006/ERR5206906/ERR5206906_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/005/ERR5206925/ERR5206925_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/009/ERR5206889/ERR5206889.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/002/ERR5206882/ERR5206882.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/008/ERR5206928/ERR5206928_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/004/ERR5206924/ERR5206924_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/009/ERR5206919/ERR5206919_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/009/ERR5206909/ERR5206909_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/002/ERR5206902/ERR5206902_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR520/001/ERR5206921/ERR5206921_1.fastq.gzprimaryOK200GenomicsEuropean Bioinformatics InstituteAstraZenecahttps://www.ebi.ac.uk/ena/browser/view/PRJEB42741ArrayExpressRNAseq profiling of AZD3458 monotherapy and combination treatment with anti-PD-1 of whole tumors, isolated tumor macrophages (Mac) (CD45+CD11b+F4/80+), whole blood (PB) and tumor draining lymph nodes (TDLN) were assessed to elucidate further mechanisms leading to enhanced combination activity.ENAfalseRNAseq profiling of tumor, tumor-draining-lymph nodes, blood and tumor-associated macrophages of MC38 mice treated with the PI3Kg inhibitor AZD3458 and a combination of AZD3458 and anti-PD-1RNAseq profiling of tumor, tumor-draining-lymph nodes, blood and tumor-associated macrophages of MC38 mice treated with the PI3Kg inhibitor AZD3458 and a combination of AZD3458 and anti-PD-12021-01-282021-03-01PRJEB42741