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Recently, attention has turned to molecular mechanisms, which could uncover potential biomarkers of fertility. One of these mechanisms is DNA methylation, which together with other epigenetic mechanisms is essential for the fertilising sperm to drive normal embryo development and establish a viable pregnancy. In this study we hypothesised that bull sperm DNA methylation patterns are related to bull fertility. We therefore investigated DNA methylation patterns from bulls used in artificial insemination with contrasting fertility scores.ENAPostnidation Embryo, Subfecundity, Materials, Pre-implantation Embryo Development, World, Marital Fertility., World Fertility Surveys, Post implantation Embryo Development, Post-implantation Embryo Development, Post-implantation, Preimplantation, Gene, Fertility, DNA Methylations, Development, Cistrons, Pre implantation Embryo Development, embryonic aspects, Embryonic Programming, World Fertility Survey, Prenidation Embryo Development, Fertility Preferences, Embryo Development, Determinant, Below Replacement, Embryonic Developments, Natural Fertility, Genetic Materials, Survey, Preference, Animal, World Fertility, Determinants, Genetic Material, Postimplantation Embryo Development, Fertility Surveys, Fecundity, Embryonic, Postnidation, Embryo, Fertility Incentives, DNA methylation maintenance, Genetic, Natural, Postnidation Embryo Development, Embryogenesis, Pre-implantation, DNA methylation, Preferences, fetal development, Preimplantation Embryo Development, Fertility Determinants, Differential, embryonic development, Marital, Material, prenatal development, Below Replacement Fertility, Fertility Determinant, Surveys, Fertility Preference, Cistron, Fertility Incentive, DNA, Fecundability, Methylations, Postimplantation, Differential Fertility, Methylation, Embryonic Programmings, Fertility SurveyY-Chromosome-Bearing, X-Bearing Sperm, Subfecundity, Sperm, World, Marital Fertility., World Fertility Surveys, Fertility, DNA Methylations, Y-Chromosome-Bearing Sperm, spermatozoon, World Fertility Survey, Fertility Preferences, Determinant, Below Replacement, Spermatozoon, Natural Fertility, Survey, Preference, World Fertility, Determinants, Y-Bearing, Y Bearing Sperm, Fertility Surveys, Fecundity, X-Chromosome-Bearing Sperm, sperm cell, X-Chromosome-Bearing, Fertility Incentives, X-Bearing, DNA methylation maintenance, Natural, X-Bearing Sperms, DNA methylation, spermatozoid, X Bearing Sperm, Preferences, X-Chromosome-Bearing Sperms, Fertility Determinants, seminal fluid, Y Chromosome Bearing Sperm, Y-Bearing Sperms, Differential, Y-Bearing Sperm, Marital, sperm, X Chromosome Bearing Sperm, Sperms, Y-Chromosome-Bearing Sperms, Below Replacement Fertility, Fertility Determinant, Surveys, Fertility Preference, SPERM, Fertility Incentive, DNA, Fecundability, Methylations, Differential Fertility, Methylation, Fertility Survey, ejaculatefalseDNA methylation in the sperm of Holstein bulls with contrasting fertilityDNA methylation at discrete CpGs and genes involved in embryonic development is related to bull fertility2022-04-282022-04-28PRJEB49406